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Volumn 156, Issue 1, 2009, Pages 172-182

The effect of proteasome inhibitor MG132 on experimental inflammatory bowel disease

Author keywords

Epithelial regeneration; IBD; MDR1; NF B; Proteasome inhibitor

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR ALPHA;

EID: 61849110417     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2008.03872.x     Document Type: Article
Times cited : (58)

References (42)
  • 1
    • 0032412057 scopus 로고    scopus 로고
    • Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice
    • Sellon RK, Tonkonogy S, Schultz M et al. Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice. Infect Immun 1998 66 : 5224 31.
    • (1998) Infect Immun , vol.66 , pp. 5224-31
    • Sellon, R.K.1    Tonkonogy, S.2    Schultz, M.3
  • 2
    • 17144383927 scopus 로고    scopus 로고
    • Variable phenotype of enterocolitis in interleukin 10-deficient mice monoassociated with two different commensal bacteria
    • Kim SC, Tonkonogy SL, Albright CA et al. Variable phenotype of enterocolitis in interleukin 10-deficient mice monoassociated with two different commensal bacteria. Gastroenterology 2005 128 : 891 906.
    • (2005) Gastroenterology , vol.128 , pp. 891-906
    • Kim, S.C.1    Tonkonogy, S.L.2    Albright, C.A.3
  • 3
    • 0028069352 scopus 로고
    • Cytokines in intestinal inflammation: Pathophysiological and clinical considerations
    • Sartor RB. Cytokines in intestinal inflammation: pathophysiological and clinical considerations. Gastroenterology 1994 106 : 533 9.
    • (1994) Gastroenterology , vol.106 , pp. 533-9
    • Sartor, R.B.1
  • 4
    • 0024344814 scopus 로고
    • Enhanced production of interleukin 1-Β by mononuclear cells isolated from mucosa with active ulcerative colitis of Crohn's disease
    • Mahida YR, Wu K, Jewell DP. Enhanced production of interleukin 1-Β by mononuclear cells isolated from mucosa with active ulcerative colitis of Crohn's disease. Gut 1989 30 : 835 8.
    • (1989) Gut , vol.30 , pp. 835-8
    • Mahida, Y.R.1    Wu, K.2    Jewell, D.P.3
  • 5
    • 0027451455 scopus 로고
    • Enhanced secretion of tumor necrosis factor-alpha, IL-6, and IL-1 beta by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn's disease
    • Reinecker HC, Steffen M, Witthoeft T et al. Enhanced secretion of tumor necrosis factor-alpha, IL-6, and IL-1 beta by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn's disease. Clin Exp Immunol 1993 94 : 174 81.
    • (1993) Clin Exp Immunol , vol.94 , pp. 174-81
    • Reinecker, H.C.1    Steffen, M.2    Witthoeft, T.3
  • 6
    • 0028236232 scopus 로고
    • Tumor necrosis factor alpha-producing cells in the intestinal mucosa of children with inflammatory bowel disease
    • Breese EJ, Michie CA, Nicholls SW et al. Tumor necrosis factor alpha-producing cells in the intestinal mucosa of children with inflammatory bowel disease. Gastroenterology 1994 106 : 1455 66.
    • (1994) Gastroenterology , vol.106 , pp. 1455-66
    • Breese, E.J.1    Michie, C.A.2    Nicholls, S.W.3
  • 7
    • 0033625715 scopus 로고    scopus 로고
    • NF-κB/Rel/IκB: Implications in gastrointestinal diseases
    • Schmid RM, Adler G. NF-κB/Rel/IκB: implications in gastrointestinal diseases. Gastroenterology 2000 118 : 1208 28.
    • (2000) Gastroenterology , vol.118 , pp. 1208-28
    • Schmid, R.M.1    Adler, G.2
  • 8
    • 0034084163 scopus 로고    scopus 로고
    • Phospholylation meets ubiquitination: The control of NF-kappa B activity
    • Karin M, Ben Neriah Y. Phospholylation meets ubiquitination: the control of NF-kappa B activity. Annu Rev Immunol 2000 18 : 621 63.
    • (2000) Annu Rev Immunol , vol.18 , pp. 621-63
    • Karin, M.1    Ben Neriah, Y.2
  • 9
    • 0025266685 scopus 로고
    • Activation in vitro of NF-kappa B by phosphorylation of its inhibitor i kappa B
    • Ghosh S, Baltimore D. Activation in vitro of NF-kappa B by phosphorylation of its inhibitor I kappa B. Nature 1990 344 : 678 82.
    • (1990) Nature , vol.344 , pp. 678-82
    • Ghosh, S.1    Baltimore, D.2
  • 10
    • 0027176524 scopus 로고
    • Rapid proteolysis of i kappa B-alpha is necessary for activation of transcription factor NF-kappa B
    • Henkel T, Machleidt T, Alkalay I, Kronke M, Ben-Neriah Y, Baeuerle PA. Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B. Nature 1993 365 : 182 5.
    • (1993) Nature , vol.365 , pp. 182-5
    • Henkel, T.1    MacHleidt, T.2    Alkalay, I.3    Kronke, M.4    Ben-Neriah, Y.5    Baeuerle, P.A.6
  • 11
    • 0036234459 scopus 로고    scopus 로고
    • Missing pieces in the NF-kappa B puzzle
    • Suppl
    • Ghosh S, Karin M. Missing pieces in the NF-kappa B puzzle. Cell 2002 109 (Suppl S81 96.
    • (2002) Cell , vol.109 , pp. 81-96
    • Ghosh, S.1    Karin, M.2
  • 12
    • 4444376712 scopus 로고    scopus 로고
    • Signaling to NF-kappa B
    • Hayden MS, Ghosh S. Signaling to NF-kappa B. Genes Dev 2004 18 : 2195 224.
    • (2004) Genes Dev , vol.18 , pp. 2195-224
    • Hayden, M.S.1    Ghosh, S.2
  • 13
    • 17644383370 scopus 로고    scopus 로고
    • A pervasive role of ubiquitin conjugation in activation and termination of Ikappa B kinase pathways
    • Krappmann D, Scheidereit C. A pervasive role of ubiquitin conjugation in activation and termination of Ikappa B kinase pathways. EMBO Rep 2005 6 : 321 6.
    • (2005) EMBO Rep , vol.6 , pp. 321-6
    • Krappmann, D.1    Scheidereit, C.2
  • 14
    • 0031925362 scopus 로고    scopus 로고
    • Activation of nuclear factor κb in inflammatory bowel disease
    • Schreiber S, Nikolaus S, Hampe J. Activation of nuclear factor κB in inflammatory bowel disease. Gut 1998 42 : 477 84.
    • (1998) Gut , vol.42 , pp. 477-84
    • Schreiber, S.1    Nikolaus, S.2    Hampe, J.3
  • 15
    • 0029836444 scopus 로고    scopus 로고
    • Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-κB abrogates established experimental colitis in mice
    • Neurath MF, Pettersson S, Meyer zum Buschenfelde KH, Strober W. Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-κB abrogates established experimental colitis in mice. Nat Med 1996 2 : 998 1004.
    • (1996) Nat Med , vol.2 , pp. 998-1004
    • Neurath, M.F.1    Pettersson, S.2    Meyer Zum Buschenfelde, K.H.3    Strober, W.4
  • 16
    • 0028018268 scopus 로고
    • The ubiquitin-proteasome proteolytic pathway
    • Ciechanover A. The ubiquitin-proteasome proteolytic pathway. Cell 1994 79 : 13 21.
    • (1994) Cell , vol.79 , pp. 13-21
    • Ciechanover, A.1
  • 17
    • 2342613652 scopus 로고    scopus 로고
    • The proteasome: A suitable antineoplastic target
    • Adams J. The proteasome: a suitable antineoplastic target. Nat Rev Cancer 2004 4 : 349 60.
    • (2004) Nat Rev Cancer , vol.4 , pp. 349-60
    • Adams, J.1
  • 18
    • 0027980321 scopus 로고
    • The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B
    • Palombella VJ, Rando OJ, Goldberg AL, Maniatis T. The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B. Cell 1994 78 : 773 85.
    • (1994) Cell , vol.78 , pp. 773-85
    • Palombella, V.J.1    Rando, O.J.2    Goldberg, A.L.3    Maniatis, T.4
  • 19
    • 0028148227 scopus 로고
    • A proteasome inhibitor prevents activation of NF-kappa B and stablizes a newly phosphorylated form i kappa B-alpha that is still bound to NF-kappa B
    • Traenckner EB, Wilk S, Baeuerle PA. A proteasome inhibitor prevents activation of NF-kappa B and stablizes a newly phosphorylated form I kappa B-alpha that is still bound to NF-kappa B. EMBO J 1994 13 : 5433 41.
    • (1994) EMBO J , vol.13 , pp. 5433-41
    • Traenckner, E.B.1    Wilk, S.2    Baeuerle, P.A.3
  • 20
    • 0028970734 scopus 로고
    • Stimulation-dependent i kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway
    • Alkalay I, Yaron A, Hatzubai A, Orian A, Ciechanover A, Ben-Neriah Y. Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway. Proc Natl Acad Sci USA 1995 92 : 10599 603.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 10599-603
    • Alkalay, I.1    Yaron, A.2    Hatzubai, A.3    Orian, A.4    Ciechanover, A.5    Ben-Neriah, Y.6
  • 21
    • 0037569481 scopus 로고    scopus 로고
    • Proteasome inhibition: A new anti-inflammatory strategy
    • Elliott PJ, Zollner TM, Boehncke WH. Proteasome inhibition: a new anti-inflammatory strategy. J Mol Med 2003 81 : 235 45.
    • (2003) J Mol Med , vol.81 , pp. 235-45
    • Elliott, P.J.1    Zollner, T.M.2    Boehncke, W.H.3
  • 22
    • 33845306274 scopus 로고    scopus 로고
    • Proteasome-mediated degradation of IκBα and processing of p105 in Crohn disease and ulcerative colitis
    • Visekruna A, Joeris T, Seidel D et al. Proteasome-mediated degradation of IκBα and processing of p105 in Crohn disease and ulcerative colitis. J Clin Invest 2006 116 : 3195 203.
    • (2006) J Clin Invest , vol.116 , pp. 3195-203
    • Visekruna, A.1    Joeris, T.2    Seidel, D.3
  • 24
    • 33744546642 scopus 로고    scopus 로고
    • Implication of TNF-related apoptosis-inducing ligand in inflammatory intestinal epithelial lesions
    • Begue B, Wajant H, Bambou JC et al. Implication of TNF-related apoptosis-inducing ligand in inflammatory intestinal epithelial lesions. Gastroenterology 2006 130 : 1962 74.
    • (2006) Gastroenterology , vol.130 , pp. 1962-74
    • Begue, B.1    Wajant, H.2    Bambou, J.C.3
  • 25
    • 1542514714 scopus 로고    scopus 로고
    • Aberrant Toll receptor expression and endotoxin hypersensitivity in mice lacking a functional TGF-Β1 signaling pathway
    • Francis NM, Jin W, Wahl SM. Aberrant Toll receptor expression and endotoxin hypersensitivity in mice lacking a functional TGF-Β1 signaling pathway. J Immunol 2004 172 : 3814 21.
    • (2004) J Immunol , vol.172 , pp. 3814-21
    • Francis, N.M.1    Jin, W.2    Wahl, S.M.3
  • 26
    • 0025181580 scopus 로고
    • A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice
    • Okayasu I, Hatakeyama S, Yamada M, Ohkusa T, Inagaki Y, Nakaya R. A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice. Gastroenterology 1990 98 : 694 702.
    • (1990) Gastroenterology , vol.98 , pp. 694-702
    • Okayasu, I.1    Hatakeyama, S.2    Yamada, M.3    Ohkusa, T.4    Inagaki, Y.5    Nakaya, R.6
  • 27
    • 0035123651 scopus 로고    scopus 로고
    • Enhanced survival and mucosal repair after dextran sodium sulfate-induced colitis in transgenic mice that overexpress growth hormone
    • Williams KL, Fuller CR, Dieleman LA et al. Enhanced survival and mucosal repair after dextran sodium sulfate-induced colitis in transgenic mice that overexpress growth hormone. Gastroenterology 2001 120 : 925 37.
    • (2001) Gastroenterology , vol.120 , pp. 925-37
    • Williams, K.L.1    Fuller, C.R.2    Dieleman, L.A.3
  • 29
    • 0019903249 scopus 로고
    • Monoclonal antibody to 5-bromo- and 5-iododeoxyuridine: A new reagent for detection of DNA replication
    • Gratzner HG. Monoclonal antibody to 5-bromo- and 5-iododeoxyuridine: a new reagent for detection of DNA replication. Science 1982 218 : 474 5.
    • (1982) Science , vol.218 , pp. 474-5
    • Gratzner, H.G.1
  • 30
    • 0024348029 scopus 로고
    • 3H]-thymidine for studies of hepatocellular proliferation in rodents
    • 3H]-thymidine for studies of hepatocellular proliferation in rodents. Carcinogenesis 1989 10 : 1341 3.
    • (1989) Carcinogenesis , vol.10 , pp. 1341-3
    • Lanier, T.L.1    Berger, E.K.2    Eacho, P.I.3
  • 31
    • 0026705808 scopus 로고
    • Migration of IEC-6 cells: A model for mucosal healing
    • 435.
    • Mccormack SA, Viar MJ, Johnson LR. Migration of IEC-6 cells: a model for mucosal healing. Am J Physiol 1992 263 : G426 435.
    • (1992) Am J Physiol , vol.263 , pp. 426
    • McCormack, S.A.1    Viar, M.J.2    Johnson, L.R.3
  • 32
    • 0027160764 scopus 로고
    • Transforming growth factor beta regulation of migration in wounded rat intestinal epithelial monolayers
    • Ciacci C, Lind SE, Podolsky DK. Transforming growth factor beta regulation of migration in wounded rat intestinal epithelial monolayers. Gastroenterology 1993 105 : 93 101.
    • (1993) Gastroenterology , vol.105 , pp. 93-101
    • Ciacci, C.1    Lind, S.E.2    Podolsky, D.K.3
  • 33
    • 0030954732 scopus 로고    scopus 로고
    • A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor α for Crohn's disease
    • Targan SR, Hanauer SB, van Deventer SJ et al. A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor α for Crohn's disease. N Engl J Med 1997 337 : 1029 35.
    • (1997) N Engl J Med , vol.337 , pp. 1029-35
    • Targan, S.R.1    Hanauer, S.B.2    Van Deventer, S.J.3
  • 34
    • 0037413468 scopus 로고    scopus 로고
    • Natalizumab for active Crohn's disease
    • Ghosh S, Goldin E, Gordon FH et al. Natalizumab for active Crohn's disease. N Engl J Med 2003 348 : 24 32.
    • (2003) N Engl J Med , vol.348 , pp. 24-32
    • Ghosh, S.1    Goldin, E.2    Gordon, F.H.3
  • 35
    • 0031595210 scopus 로고    scopus 로고
    • Nuclear factor κb is activated in macrophages and epithelial cells of inflamed intestinal mucosa
    • Rogler G, Brand K, Vogl D et al. Nuclear factor κB is activated in macrophages and epithelial cells of inflamed intestinal mucosa. Gastroenterology 1998 115 : 357 69.
    • (1998) Gastroenterology , vol.115 , pp. 357-69
    • Rogler, G.1    Brand, K.2    Vogl, D.3
  • 36
    • 14044250862 scopus 로고    scopus 로고
    • IL-10 gene-deficient mice lack TGF-Β/Smad signaling and fail to inhibit proinflammatory gene expression in intestinal epithelial cells after the colonization with colitogenic Enterococcus faecalis
    • Ruiz PA, Shkoda A, Kim SC, Sartor RB, Haller D. IL-10 gene-deficient mice lack TGF-Β/Smad signaling and fail to inhibit proinflammatory gene expression in intestinal epithelial cells after the colonization with colitogenic Enterococcus faecalis. Gastroenterology 2005 174 : 2990 9.
    • (2005) Gastroenterology , vol.174 , pp. 2990-9
    • Ruiz, P.A.1    Shkoda, A.2    Kim, S.C.3    Sartor, R.B.4    Haller, D.5
  • 37
    • 0027224059 scopus 로고
    • Clinicopathologic study of dextran sulfate sodium experimental murine colitis
    • Cooper HS, Murthy SNS, Shah RS, Sedergran DJ. Clinicopathologic study of dextran sulfate sodium experimental murine colitis. Lab Invest 1993 69 : 238 49.
    • (1993) Lab Invest , vol.69 , pp. 238-49
    • Cooper, H.S.1    Murthy, S.N.S.2    Shah, R.S.3    Sedergran, D.J.4
  • 39
    • 0036074018 scopus 로고    scopus 로고
    • Mammalian ABC transporters in health and disease
    • Borst P, Elferink RO. Mammalian ABC transporters in health and disease. Annu Rev Biochem 2002 71 : 537 92.
    • (2002) Annu Rev Biochem , vol.71 , pp. 537-92
    • Borst, P.1    Elferink, R.O.2
  • 40
    • 0037624566 scopus 로고    scopus 로고
    • Multidrug resistance 1 gene (P-glycoprotein 170): An important determinant in gastrointestinal disease?
    • Ho GT, Moodie FM, Satsangi J. Multidrug resistance 1 gene (P-glycoprotein 170): an important determinant in gastrointestinal disease? Gut 2003 52 : 759 66.
    • (2003) Gut , vol.52 , pp. 759-66
    • Ho, G.T.1    Moodie, F.M.2    Satsangi, J.3
  • 41
    • 0032534043 scopus 로고    scopus 로고
    • A novel model of inflammatory bowel disease: Mice deficient for the multiple drug resistance gene, mdr1a, spontaneously develop colitis
    • Panwala CM, Jones JC, Viney JL. A novel model of inflammatory bowel disease: mice deficient for the multiple drug resistance gene, mdr1a, spontaneously develop colitis. J Immunol 1998 161 : 5733 44.
    • (1998) J Immunol , vol.161 , pp. 5733-44
    • Panwala, C.M.1    Jones, J.C.2    Viney, J.L.3
  • 42
    • 0037150228 scopus 로고    scopus 로고
    • Induction of human MDR1 gene expression by 2-acetylaminofluorene is mediated by effectors of the phosphoinositide 3-kinase pathway that activate NF-kappaB signaling
    • Kuo MT, Liu Z, Wei Y et al. Induction of human MDR1 gene expression by 2-acetylaminofluorene is mediated by effectors of the phosphoinositide 3-kinase pathway that activate NF-kappaB signaling. Oncogene 2002 21 : 1945 54.
    • (2002) Oncogene , vol.21 , pp. 1945-54
    • Kuo, M.T.1    Liu, Z.2    Wei, Y.3


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