메뉴 건너뛰기




Volumn 22, Issue 1, 2009, Pages 115-128

Thrombosis associated with angiogenesis inhibitors

Author keywords

angiogenesis; anti angiogenic agents; bavacizumab; cancer; lenalidomide; semaxibin; sorafenib; sunitinib; thalidomide; thrombosis

Indexed keywords

ACETYLSALICYLIC ACID; ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; BEVACIZUMAB; CAPECITABINE; CARBOPLATIN; CISPLATIN; DEXAMETHASONE; DOXORUBICIN; ERYTHROPOIETIN; FLUOROURACIL; FOLINIC ACID; GEMCITABINE; IRINOTECAN; LENALIDOMIDE; LOW MOLECULAR WEIGHT HEPARIN; MELPHALAN; OXALIPLATIN; PACLITAXEL; PLACEBO; POMALIDOMIDE; PREDNISONE; SEMAXANIB; SORAFENIB; SUNITINIB; THALIDOMIDE; THALIDOMIDE DERIVATIVE; UNINDEXED DRUG; VASCULOTROPIN INHIBITOR; VATALANIB;

EID: 61649127110     PISSN: 15216926     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.beha.2009.01.001     Document Type: Review
Times cited : (101)

References (100)
  • 1
    • 0025289680 scopus 로고
    • Heparin abolishes the chemotherapy-induced increases in plasma fibrinopeptide A levels
    • Edwards R.L., Klaus M., Matthews E., et al. Heparin abolishes the chemotherapy-induced increases in plasma fibrinopeptide A levels. Am J Med 89 (1990) 25-28
    • (1990) Am J Med , vol.89 , pp. 25-28
    • Edwards, R.L.1    Klaus, M.2    Matthews, E.3
  • 2
    • 0034949453 scopus 로고    scopus 로고
    • Anticancer drugs induce necrosis of human endothelial cells involving both oncosis and apoptosis
    • Mailloux A., Grenet K., Bruneel A., et al. Anticancer drugs induce necrosis of human endothelial cells involving both oncosis and apoptosis. Eur J Cell Biol 80 (2001) 442-449
    • (2001) Eur J Cell Biol , vol.80 , pp. 442-449
    • Mailloux, A.1    Grenet, K.2    Bruneel, A.3
  • 3
    • 55549105814 scopus 로고    scopus 로고
    • Hemostatic complications of angiogenesis inhibitors in cancer patients
    • Elice F., Jacoub J., Rickles F.R., et al. Hemostatic complications of angiogenesis inhibitors in cancer patients. Am J Hematol 83 (2008) 862-870
    • (2008) Am J Hematol , vol.83 , pp. 862-870
    • Elice, F.1    Jacoub, J.2    Rickles, F.R.3
  • 4
    • 33748446247 scopus 로고    scopus 로고
    • The pathogenesis of thrombosis in cancer
    • Falanga A., and Rickles F.R. The pathogenesis of thrombosis in cancer. New Oncol Thromb 1 (2005) 9-16
    • (2005) New Oncol Thromb , vol.1 , pp. 9-16
    • Falanga, A.1    Rickles, F.R.2
  • 5
    • 28344456074 scopus 로고    scopus 로고
    • The role of endothelial cell apoptosis in inflammatory and immune diseases
    • Winn R., and Harlan J. The role of endothelial cell apoptosis in inflammatory and immune diseases. J Thromb Haemost 3 (2005) 1815-1824
    • (2005) J Thromb Haemost , vol.3 , pp. 1815-1824
    • Winn, R.1    Harlan, J.2
  • 6
    • 33845781028 scopus 로고    scopus 로고
    • From Trousseau to angiogenesis: the link between the haemostatic system and cancer
    • Nijziel M.R., van Oerle R., Hillen H.F.P., et al. From Trousseau to angiogenesis: the link between the haemostatic system and cancer. Neth J Med 64 (2006) 403-410
    • (2006) Neth J Med , vol.64 , pp. 403-410
    • Nijziel, M.R.1    van Oerle, R.2    Hillen, H.F.P.3
  • 7
    • 0031882775 scopus 로고    scopus 로고
    • Activation of coagulation and angiogenesis in cancer: immunohistochemical localization in situ of clotting proteins and vascular endothelial growth factor in human cancer
    • Shoji M., Hancock W.W., Abe K., et al. Activation of coagulation and angiogenesis in cancer: immunohistochemical localization in situ of clotting proteins and vascular endothelial growth factor in human cancer. Am J Pathol 52 (1998) 399-411
    • (1998) Am J Pathol , vol.52 , pp. 399-411
    • Shoji, M.1    Hancock, W.W.2    Abe, K.3
  • 8
    • 0027935431 scopus 로고
    • Tissue factor controls the balance of angiogenic and antiangiogenic properties of tumor cells in mice
    • Zhang Y., Deng Y., Luther T., et al. Tissue factor controls the balance of angiogenic and antiangiogenic properties of tumor cells in mice. J Clin Invest 94 (1994) 1320-1327
    • (1994) J Clin Invest , vol.94 , pp. 1320-1327
    • Zhang, Y.1    Deng, Y.2    Luther, T.3
  • 9
    • 13044277569 scopus 로고    scopus 로고
    • Regulation of vascular endothelial growth factor production and angiogenesis by the cytoplasmic tail of tissue factor
    • Abe K., Shoji M., Chen J., et al. Regulation of vascular endothelial growth factor production and angiogenesis by the cytoplasmic tail of tissue factor. Proc Natl Acad Sci U S A 96 (1999) 8663-8668
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 8663-8668
    • Abe, K.1    Shoji, M.2    Chen, J.3
  • 10
    • 0021193823 scopus 로고
    • Increased incidence of thromboembolism in stage IV breast cancer patients treated with a five day chemotherapy regimen. A study of 159 patients
    • Goodnough L.T., Saito H., Manni A., et al. Increased incidence of thromboembolism in stage IV breast cancer patients treated with a five day chemotherapy regimen. A study of 159 patients. Cancer 54 (1984) 1264-1268
    • (1984) Cancer , vol.54 , pp. 1264-1268
    • Goodnough, L.T.1    Saito, H.2    Manni, A.3
  • 11
    • 0023818427 scopus 로고
    • The thrombogenic effect of anticancer drug therapy in women with stage II breast cancer
    • Levine M.N., Gent M., Hirsh J., et al. The thrombogenic effect of anticancer drug therapy in women with stage II breast cancer. N Engl J Med 318 (1988) 404-407
    • (1988) N Engl J Med , vol.318 , pp. 404-407
    • Levine, M.N.1    Gent, M.2    Hirsh, J.3
  • 12
    • 0034828362 scopus 로고    scopus 로고
    • Epidemiology of thrombosis in cancer
    • Rickles F.R., and Levine M.N. Epidemiology of thrombosis in cancer. Acta Haematol 106 Suppl. (2001) 6-12
    • (2001) Acta Haematol , vol.106 , Issue.SUPPL , pp. 6-12
    • Rickles, F.R.1    Levine, M.N.2
  • 13
    • 13444256137 scopus 로고    scopus 로고
    • Malignancies, prothrombotic mutations, and the risk of venous thrombosis
    • Blom J.W., Doggen C.J., Osanto S., et al. Malignancies, prothrombotic mutations, and the risk of venous thrombosis. JAMA 293 (2005) 715-722
    • (2005) JAMA , vol.293 , pp. 715-722
    • Blom, J.W.1    Doggen, C.J.2    Osanto, S.3
  • 14
    • 0026760990 scopus 로고
    • Deep-vein thrombosis and incidence of subsequent symptomatic cancer
    • Prandoni P., Lensing A.W., Buller H.R., et al. Deep-vein thrombosis and incidence of subsequent symptomatic cancer. N Engl J Med 327 (1992) 1128-1133
    • (1992) N Engl J Med , vol.327 , pp. 1128-1133
    • Prandoni, P.1    Lensing, A.W.2    Buller, H.R.3
  • 15
    • 33644801469 scopus 로고    scopus 로고
    • The interactions between inflammation and coagulation
    • Esmon C. The interactions between inflammation and coagulation. Br J Haematol 131 (2005) 417-430
    • (2005) Br J Haematol , vol.131 , pp. 417-430
    • Esmon, C.1
  • 16
    • 53449093751 scopus 로고    scopus 로고
    • High plasma levels of soluble P-selectin are predictive of venous thromboembolism in cancer patients: results from the Vienna Cancer and Thrombosis Study (CATS)
    • Ay C., Simanek R., Vormittag R., et al. High plasma levels of soluble P-selectin are predictive of venous thromboembolism in cancer patients: results from the Vienna Cancer and Thrombosis Study (CATS). Blood 112 (2008) 2703-2708
    • (2008) Blood , vol.112 , pp. 2703-2708
    • Ay, C.1    Simanek, R.2    Vormittag, R.3
  • 17
    • 0035880229 scopus 로고    scopus 로고
    • Extended survival in advanced and refractory multiple myeloma after single-agent thalidomide: identification of prognostic factors in a phase 2 study of 169 patients
    • Barlogie B., Desikan R., Eddlemon P., et al. Extended survival in advanced and refractory multiple myeloma after single-agent thalidomide: identification of prognostic factors in a phase 2 study of 169 patients. Blood 98 (2001) 492-494
    • (2001) Blood , vol.98 , pp. 492-494
    • Barlogie, B.1    Desikan, R.2    Eddlemon, P.3
  • 18
    • 0036212935 scopus 로고    scopus 로고
    • Salvage therapy with thalidomide in patients with advanced relapsed/refractory multiple myeloma
    • Tosi P., Zamagni E., Cellini C., et al. Salvage therapy with thalidomide in patients with advanced relapsed/refractory multiple myeloma. Haematologica 87 (2002) 408-414
    • (2002) Haematologica , vol.87 , pp. 408-414
    • Tosi, P.1    Zamagni, E.2    Cellini, C.3
  • 19
    • 0037216068 scopus 로고    scopus 로고
    • Response rate, durability of response, and survival after thalidomide therapy for relapsed multiple myeloma
    • Kumar S., Gertz M.A., Dispenzieri A., et al. Response rate, durability of response, and survival after thalidomide therapy for relapsed multiple myeloma. Mayo Clin Proc 78 (2003) 34-39
    • (2003) Mayo Clin Proc , vol.78 , pp. 34-39
    • Kumar, S.1    Gertz, M.A.2    Dispenzieri, A.3
  • 20
    • 0037396605 scopus 로고    scopus 로고
    • Thalidomide as initial therapy for early-stage myeloma
    • Rajkumar S.V., Gertz M.A., Lacy M.Q., et al. Thalidomide as initial therapy for early-stage myeloma. Leukemia 17 (2003) 775-779
    • (2003) Leukemia , vol.17 , pp. 775-779
    • Rajkumar, S.V.1    Gertz, M.A.2    Lacy, M.Q.3
  • 21
    • 4544386351 scopus 로고    scopus 로고
    • Efficacy of low-dose thalidomide and dexamethasone as first salvage regimen in multiple myeloma
    • Palumbo A., Bertola A., Falco P., et al. Efficacy of low-dose thalidomide and dexamethasone as first salvage regimen in multiple myeloma. Hematol J 5 (2004) 318-324
    • (2004) Hematol J , vol.5 , pp. 318-324
    • Palumbo, A.1    Bertola, A.2    Falco, P.3
  • 22
    • 0034899464 scopus 로고    scopus 로고
    • Thalidomide and dexamethasone combination for refractory multiple myeloma
    • Dimopoulos M.A., Zervas K., Kouvatseas G., et al. Thalidomide and dexamethasone combination for refractory multiple myeloma. Ann Oncol 12 (2001) 991-995
    • (2001) Ann Oncol , vol.12 , pp. 991-995
    • Dimopoulos, M.A.1    Zervas, K.2    Kouvatseas, G.3
  • 23
    • 0036843032 scopus 로고    scopus 로고
    • Combination therapy with thalidomide plus dexamethasone for newly diagnosed myeloma
    • Rajkumar S.V., Hayman S., Gertz M.A., et al. Combination therapy with thalidomide plus dexamethasone for newly diagnosed myeloma. J Clin Oncol 20 (2002) 4319-4323
    • (2002) J Clin Oncol , vol.20 , pp. 4319-4323
    • Rajkumar, S.V.1    Hayman, S.2    Gertz, M.A.3
  • 24
    • 0037105601 scopus 로고    scopus 로고
    • Deep-vein thrombosis in patients with multiple myeloma receiving first-line thalidomide-dexamethasone therapy
    • Cavo M., Zamagni E., Cellini C., et al. Deep-vein thrombosis in patients with multiple myeloma receiving first-line thalidomide-dexamethasone therapy. Blood 100 (2002) 2272-2273
    • (2002) Blood , vol.100 , pp. 2272-2273
    • Cavo, M.1    Zamagni, E.2    Cellini, C.3
  • 25
    • 0037103292 scopus 로고    scopus 로고
    • Thrombogenic activity of doxorubicin in myeloma patients receiving thalidomide: implications for therapy
    • Zangari M., Siegel E., Barlogie B., et al. Thrombogenic activity of doxorubicin in myeloma patients receiving thalidomide: implications for therapy. Blood 100 (2002) 1168-1171
    • (2002) Blood , vol.100 , pp. 1168-1171
    • Zangari, M.1    Siegel, E.2    Barlogie, B.3
  • 26
    • 4544332965 scopus 로고    scopus 로고
    • Deep vein thrombosis in patients with multiple myeloma treated with thalidomide and chemotherapy: effects of prophylactic and therapeutic anticoagulation
    • Zangari M., Barlogie B., Anaissie E., et al. Deep vein thrombosis in patients with multiple myeloma treated with thalidomide and chemotherapy: effects of prophylactic and therapeutic anticoagulation. Br J Haematol 126 (2004) 715-721
    • (2004) Br J Haematol , vol.126 , pp. 715-721
    • Zangari, M.1    Barlogie, B.2    Anaissie, E.3
  • 27
    • 0012271566 scopus 로고    scopus 로고
    • A study of the safety and efficacy of thalidomide combined with vincristine, adriamycin and dexamethasone (T-VAD) in the treatment of younger patients with multiple myeloma: a UK Myeloma Forum Pilot Study
    • Oakervee H., Brownell A., Cervi P., et al. A study of the safety and efficacy of thalidomide combined with vincristine, adriamycin and dexamethasone (T-VAD) in the treatment of younger patients with multiple myeloma: a UK Myeloma Forum Pilot Study. Br J Haematol 117 Suppl. 1 (2002) 65
    • (2002) Br J Haematol , vol.117 , Issue.SUPPL. 1 , pp. 65
    • Oakervee, H.1    Brownell, A.2    Cervi, P.3
  • 28
    • 33644843725 scopus 로고    scopus 로고
    • Oral melphalan and prednisone chemotherapy plus thalidomide compared with melphalan and prednisone alone in elderly patients with multiple myeloma: randomized controlled trial
    • Palumbo A., Bringhen S., Caravita T., et al., Italian Multiple Myeloma Network, GIMEMA. Oral melphalan and prednisone chemotherapy plus thalidomide compared with melphalan and prednisone alone in elderly patients with multiple myeloma: randomized controlled trial. Lancet 367 (2006) 825-831
    • (2006) Lancet , vol.367 , pp. 825-831
    • Palumbo, A.1    Bringhen, S.2    Caravita, T.3
  • 29
    • 0035469858 scopus 로고    scopus 로고
    • Increased risk of deep-vein thrombosis in patients with multiple myeloma receiving thalidomide and chemotherapy
    • Zangari M., Anaissie E., Barlogie B., et al. Increased risk of deep-vein thrombosis in patients with multiple myeloma receiving thalidomide and chemotherapy. Blood 98 (2001) 1614-1615
    • (2001) Blood , vol.98 , pp. 1614-1615
    • Zangari, M.1    Anaissie, E.2    Barlogie, B.3
  • 30
    • 33746054911 scopus 로고    scopus 로고
    • Acquired resistance to activated protein C (aAPCR) in multiple myeloma is a transitory abnormality associated with an increased risk of venous thromboembolism
    • Elice F., Fink L., Tricot G., et al. Acquired resistance to activated protein C (aAPCR) in multiple myeloma is a transitory abnormality associated with an increased risk of venous thromboembolism. Br J Haematol 134 (2006) 399-405
    • (2006) Br J Haematol , vol.134 , pp. 399-405
    • Elice, F.1    Fink, L.2    Tricot, G.3
  • 31
    • 38049113182 scopus 로고    scopus 로고
    • Phase 2 study of lenalidomide in transfusion-dependent, low-risk, and intermediate-1 risk myelodysplastic syndromes with karyotypes other than deletion 5q
    • Raza A., Reeves J.A., Feldman E.J., et al. Phase 2 study of lenalidomide in transfusion-dependent, low-risk, and intermediate-1 risk myelodysplastic syndromes with karyotypes other than deletion 5q. Blood 111 (2008) 86-93
    • (2008) Blood , vol.111 , pp. 86-93
    • Raza, A.1    Reeves, J.A.2    Feldman, E.J.3
  • 32
    • 36349023319 scopus 로고    scopus 로고
    • Lenalidomide plus dexamethasone for relapsed or refractory multiple myeloma
    • Dimopoulos M., Spencer A., Attal M., et al., Multiple Myeloma (010) Study Investigators. Lenalidomide plus dexamethasone for relapsed or refractory multiple myeloma. N Engl J Med 357 (2007) 2123-2132
    • (2007) N Engl J Med , vol.357 , pp. 2123-2132
    • Dimopoulos, M.1    Spencer, A.2    Attal, M.3
  • 33
    • 33745590139 scopus 로고    scopus 로고
    • Thrombotic complications in patients with newly diagnosed multiple myeloma treated with lenalidomide and dexamethasone: benefit of aspirin prophylaxis
    • Zonder J.A., Barlogie B., Durie B.G., et al. Thrombotic complications in patients with newly diagnosed multiple myeloma treated with lenalidomide and dexamethasone: benefit of aspirin prophylaxis. Blood 108 (2006) 403
    • (2006) Blood , vol.108 , pp. 403
    • Zonder, J.A.1    Barlogie, B.2    Durie, B.G.3
  • 34
    • 33750607347 scopus 로고    scopus 로고
    • A randomized phase 2 study of lenalidomide therapy for patients with relapsed or relapsed and refractory multiple myeloma
    • Richardson P.G., Blood E., Mitsiades C.S., et al. A randomized phase 2 study of lenalidomide therapy for patients with relapsed or relapsed and refractory multiple myeloma. Blood 108 (2006) 3458-3464
    • (2006) Blood , vol.108 , pp. 3458-3464
    • Richardson, P.G.1    Blood, E.2    Mitsiades, C.S.3
  • 35
    • 33744822953 scopus 로고    scopus 로고
    • Prophylactic low-dose aspirin is effective as antithrombotic therapy in patients receiving combination thalidomide or lenalidomide. ASH Annual Meeting Abstracts
    • (abstract)
    • Niesvizky R., Martinez-Banos D.M., Gelbshtein U.Y., et al. Prophylactic low-dose aspirin is effective as antithrombotic therapy in patients receiving combination thalidomide or lenalidomide. ASH Annual Meeting Abstracts. Blood 106 (2005) 3454 (abstract)
    • (2005) Blood , vol.106 , pp. 3454
    • Niesvizky, R.1    Martinez-Banos, D.M.2    Gelbshtein, U.Y.3
  • 36
    • 27744492561 scopus 로고    scopus 로고
    • Combination therapy with lenalidomide plus dexamethasone (Rev/Dex) for newly diagnosed myeloma
    • Rajkumar S.V., Hayman S.R., Lacy M.Q., et al. Combination therapy with lenalidomide plus dexamethasone (Rev/Dex) for newly diagnosed myeloma. Blood 106 (2005) 4050-4053
    • (2005) Blood , vol.106 , pp. 4050-4053
    • Rajkumar, S.V.1    Hayman, S.R.2    Lacy, M.Q.3
  • 37
    • 35348923502 scopus 로고    scopus 로고
    • Melphalan, prednisone, and lenalidomide treatment for newly diagnosed myeloma: a report from the GIMEMA-Italian Multiple Myeloma Network
    • Palumbo A., Falco P., Corradini P., et al., GIMEMA-Italian Multiple Myeloma Network. Melphalan, prednisone, and lenalidomide treatment for newly diagnosed myeloma: a report from the GIMEMA-Italian Multiple Myeloma Network. J Clin Oncol 25 (2007) 4459-4465
    • (2007) J Clin Oncol , vol.25 , pp. 4459-4465
    • Palumbo, A.1    Falco, P.2    Corradini, P.3
  • 38
    • 33845350847 scopus 로고    scopus 로고
    • Lenalidomide and pegylated liposomal doxorubicin-based chemotherapy for relapsed or refractory multiple myeloma: safety and efficacy
    • Baz R., Walker E., Karam M., et al. Lenalidomide and pegylated liposomal doxorubicin-based chemotherapy for relapsed or refractory multiple myeloma: safety and efficacy. Ann Oncol 17 (2006) 1766-1771
    • (2006) Ann Oncol , vol.17 , pp. 1766-1771
    • Baz, R.1    Walker, E.2    Karam, M.3
  • 39
    • 57049113927 scopus 로고    scopus 로고
    • Effective prophylaxis of thromboembolic complications with low molecular weight heparin in relapsed multiple myeloma patients treated with lenalidomide and dexamethasone
    • Klein U., Kosely F., Hillengaß J., et al. Effective prophylaxis of thromboembolic complications with low molecular weight heparin in relapsed multiple myeloma patients treated with lenalidomide and dexamethasone. Ann Hematol 88 1 (2009) 67-71
    • (2009) Ann Hematol , vol.88 , Issue.1 , pp. 67-71
    • Klein, U.1    Kosely, F.2    Hillengaß, J.3
  • 40
    • 4344693453 scopus 로고    scopus 로고
    • Phase I study of an immunomodulatory thalidomide analog, CC-4047, in relapse or refractory multiple myeloma
    • Schey S.A., Fields P., Bartlett J.B., et al. Phase I study of an immunomodulatory thalidomide analog, CC-4047, in relapse or refractory multiple myeloma. J Clin Oncol 22 (2004) 3269-3276
    • (2004) J Clin Oncol , vol.22 , pp. 3269-3276
    • Schey, S.A.1    Fields, P.2    Bartlett, J.B.3
  • 41
    • 40449135275 scopus 로고    scopus 로고
    • Alternate day pomalidomide retains anti-myeloma effect with reduced adverse events and evidence of in vivo immunomodulation
    • Streetly M.J., Gyertson K., Daniel Y., et al. Alternate day pomalidomide retains anti-myeloma effect with reduced adverse events and evidence of in vivo immunomodulation. Br J Haematol 141 (2008) 41-51
    • (2008) Br J Haematol , vol.141 , pp. 41-51
    • Streetly, M.J.1    Gyertson, K.2    Daniel, Y.3
  • 42
    • 0036526384 scopus 로고    scopus 로고
    • Activated protein C resistance in the absence of factor V Leiden mutation is a common finding in multiple myeloma and is associated with an increased risk of thrombotic complications
    • Zangari M., Saghafifar F., Anaissie E., et al. Activated protein C resistance in the absence of factor V Leiden mutation is a common finding in multiple myeloma and is associated with an increased risk of thrombotic complications. Blood Coagul Fibrinolysis 13 (2002) 187-192
    • (2002) Blood Coagul Fibrinolysis , vol.13 , pp. 187-192
    • Zangari, M.1    Saghafifar, F.2    Anaissie, E.3
  • 43
    • 0642341991 scopus 로고    scopus 로고
    • Extremely high levels of von Willebrand factor antigen and of procoagulant factor VIII found in multiple myeloma patients are associated with activity status but not with thalidomide treatment
    • Minnema M.C., Fijnheer R., De Groot P.G., et al. Extremely high levels of von Willebrand factor antigen and of procoagulant factor VIII found in multiple myeloma patients are associated with activity status but not with thalidomide treatment. J Thromb Haemost 1 (2003) 445-449
    • (2003) J Thromb Haemost , vol.1 , pp. 445-449
    • Minnema, M.C.1    Fijnheer, R.2    De Groot, P.G.3
  • 44
    • 16244363678 scopus 로고    scopus 로고
    • Markers of endothelial and haemostatic function in the treatment of relapsed myeloma with the immunomodulatory agent Actimid (CC-4047) and their relationship with venous thrombosis
    • Streetly M., Hunt B.J., Parmar K., et al. Markers of endothelial and haemostatic function in the treatment of relapsed myeloma with the immunomodulatory agent Actimid (CC-4047) and their relationship with venous thrombosis. Eur J Haematol 74 (2005) 293-296
    • (2005) Eur J Haematol , vol.74 , pp. 293-296
    • Streetly, M.1    Hunt, B.J.2    Parmar, K.3
  • 45
    • 0345322934 scopus 로고    scopus 로고
    • Correlation of thrombotic/embolic events (T/E) with features of hypercoagulability in previously untreated patients before and after treatment with thalidomide (T) or thalidomide-dexamethasone(TD)
    • (abstract)
    • Weber D., Ginsberg C., Walker P., et al. Correlation of thrombotic/embolic events (T/E) with features of hypercoagulability in previously untreated patients before and after treatment with thalidomide (T) or thalidomide-dexamethasone(TD). Blood 100 (2002) 787 (abstract)
    • (2002) Blood , vol.100 , pp. 787
    • Weber, D.1    Ginsberg, C.2    Walker, P.3
  • 46
    • 4444308010 scopus 로고    scopus 로고
    • Modification of thrombomodulin plasma levels in refractory myeloma patients during treatment with thalidomide and dexamethasone
    • Corso A., Lorenzi A., Terulla V., et al. Modification of thrombomodulin plasma levels in refractory myeloma patients during treatment with thalidomide and dexamethasone. Ann Hematol 83 (2004) 588-591
    • (2004) Ann Hematol , vol.83 , pp. 588-591
    • Corso, A.1    Lorenzi, A.2    Terulla, V.3
  • 47
    • 0037108279 scopus 로고    scopus 로고
    • A high rate of venous thromboembolism in a multi-institutional phase II trial of weekly intravenous gemcitabine with continuous infusion fluorouracil and daily thalidomide in patients with metastatic renal cell carcinoma
    • Desai A.A., Vogelzang N.J., Rini B.I., et al. A high rate of venous thromboembolism in a multi-institutional phase II trial of weekly intravenous gemcitabine with continuous infusion fluorouracil and daily thalidomide in patients with metastatic renal cell carcinoma. Cancer 95 (2002) 1629-1636
    • (2002) Cancer , vol.95 , pp. 1629-1636
    • Desai, A.A.1    Vogelzang, N.J.2    Rini, B.I.3
  • 48
    • 0344928503 scopus 로고    scopus 로고
    • Analysis of prothrombotic mechanisms and endothelial perturbation during treatment with angiogenesis inhibitors
    • Kuenen B.C. Analysis of prothrombotic mechanisms and endothelial perturbation during treatment with angiogenesis inhibitors. Pathophysiol Haemost Thromb 33 Suppl. 1 (2003) 13-14
    • (2003) Pathophysiol Haemost Thromb , vol.33 , Issue.SUPPL. 1 , pp. 13-14
    • Kuenen, B.C.1
  • 49
    • 4644316831 scopus 로고    scopus 로고
    • Thalidomide protects endothelial cells from doxorubicin-induced apoptosis but alters cell morphology
    • Kaushal V., Kaushal G.P., Melkaveri S.N., et al. Thalidomide protects endothelial cells from doxorubicin-induced apoptosis but alters cell morphology. J Thromb Haemost 2 (2004) 327-334
    • (2004) J Thromb Haemost , vol.2 , pp. 327-334
    • Kaushal, V.1    Kaushal, G.P.2    Melkaveri, S.N.3
  • 50
    • 0037393945 scopus 로고    scopus 로고
    • Thromboembolic events in patients with myelodysplasia syndrome receiving thalidomide in combination with darbepoietin-alpha
    • Steurer M., Sudmeier I., Stauder R., et al. Thromboembolic events in patients with myelodysplasia syndrome receiving thalidomide in combination with darbepoietin-alpha. Br J Haematol 121 (2003) 101-103
    • (2003) Br J Haematol , vol.121 , pp. 101-103
    • Steurer, M.1    Sudmeier, I.2    Stauder, R.3
  • 51
    • 4644333793 scopus 로고    scopus 로고
    • Recombinant human erythropoietin and the risk of thrombosis in patients receiving thalidomide for multiple myeloma
    • Galli M., Elice F., Crippa C., et al. Recombinant human erythropoietin and the risk of thrombosis in patients receiving thalidomide for multiple myeloma. Haematologica 89 (2004) 1141-1142
    • (2004) Haematologica , vol.89 , pp. 1141-1142
    • Galli, M.1    Elice, F.2    Crippa, C.3
  • 52
    • 41149161749 scopus 로고    scopus 로고
    • Thromboembolic events with lenalidomide-based therapy for multiple myeloma
    • Menon S.P., Rajkumar S.V., Lacy M., et al. Thromboembolic events with lenalidomide-based therapy for multiple myeloma. Cancer 112 (2008) 1522-1528
    • (2008) Cancer , vol.112 , pp. 1522-1528
    • Menon, S.P.1    Rajkumar, S.V.2    Lacy, M.3
  • 53
    • 0037208589 scopus 로고    scopus 로고
    • Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer
    • Kabbinavar F., Hurwitz H.I., and Fehrenbacher L. Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer. J Clin Oncol 21 (2003) 60-65
    • (2003) J Clin Oncol , vol.21 , pp. 60-65
    • Kabbinavar, F.1    Hurwitz, H.I.2    Fehrenbacher, L.3
  • 54
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz H., Fehrenbacher L., and Novotny W. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 350 (2004) 2335-2342
    • (2004) N Engl J Med , vol.350 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3
  • 55
    • 2942657615 scopus 로고    scopus 로고
    • Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer
    • Johnson D.H., Fehrenbacher L., Novotny W.F., et al. Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer. J Clin Oncol 22 (2004) 2184-2191
    • (2004) J Clin Oncol , vol.22 , pp. 2184-2191
    • Johnson, D.H.1    Fehrenbacher, L.2    Novotny, W.F.3
  • 56
    • 20544471876 scopus 로고    scopus 로고
    • Combined analysis of efficacy: the addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer
    • Kabbinavar F.F., Hambleton J., and Mass R.D. Combined analysis of efficacy: the addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer. J Clin Oncol 23 (2005) 3706-3712
    • (2005) J Clin Oncol , vol.23 , pp. 3706-3712
    • Kabbinavar, F.F.1    Hambleton, J.2    Mass, R.D.3
  • 57
    • 17844373871 scopus 로고    scopus 로고
    • Thromboembolic events in gastric cancer: high incidence in patients receiving irinotecan- and bevacizumab-based therapy
    • Shah M.A., Ilson D., and Kelsen D.P. Thromboembolic events in gastric cancer: high incidence in patients receiving irinotecan- and bevacizumab-based therapy. J Clin Oncol 23 (2005) 2574-2576
    • (2005) J Clin Oncol , vol.23 , pp. 2574-2576
    • Shah, M.A.1    Ilson, D.2    Kelsen, D.P.3
  • 58
    • 20044364346 scopus 로고    scopus 로고
    • Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer
    • Miller K.D., Chap L.I., Holmes F.A., et al. Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer. J Clin Oncol 23 (2005) 792-799
    • (2005) J Clin Oncol , vol.23 , pp. 792-799
    • Miller, K.D.1    Chap, L.I.2    Holmes, F.A.3
  • 59
    • 34447130180 scopus 로고    scopus 로고
    • FDA drug approval summary: bevacizumab (Avastin) plus carboplatin and paclitaxel as first-line treatment of advanced/metastatic recurrent nonsquamous non-small cell lung cancer
    • Cohen M.H., Gootenberg J., Keegan P., et al. FDA drug approval summary: bevacizumab (Avastin) plus carboplatin and paclitaxel as first-line treatment of advanced/metastatic recurrent nonsquamous non-small cell lung cancer. Oncologist 12 (2007) 713-718
    • (2007) Oncologist , vol.12 , pp. 713-718
    • Cohen, M.H.1    Gootenberg, J.2    Keegan, P.3
  • 60
    • 34248173883 scopus 로고    scopus 로고
    • Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200
    • Giantonio B.J., Catalano P.J., Meropol N.J., et al., Eastern Cooperative Oncology Group Study E3200. Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200. J Clin Oncol 25 (2007) 1539-1544
    • (2007) J Clin Oncol , vol.25 , pp. 1539-1544
    • Giantonio, B.J.1    Catalano, P.J.2    Meropol, N.J.3
  • 62
    • 18544393909 scopus 로고    scopus 로고
    • Involvement of vascular endothelial growth factor receptor-3 in maintenance of integrity of endothelial cell lining during tumor angiogenesis
    • Kubo H., Fujiwara T., Jussila L., et al. Involvement of vascular endothelial growth factor receptor-3 in maintenance of integrity of endothelial cell lining during tumor angiogenesis. Blood 96 (2000) 546-553
    • (2000) Blood , vol.96 , pp. 546-553
    • Kubo, H.1    Fujiwara, T.2    Jussila, L.3
  • 63
    • 0030022917 scopus 로고    scopus 로고
    • Effects of vascular endothelial growth factor on hemodynamics and cardiac performances
    • Yang R., Thomas G., Bunting S., et al. Effects of vascular endothelial growth factor on hemodynamics and cardiac performances. J Cardiovasc Pharmacol 27 (1996) 838-844
    • (1996) J Cardiovasc Pharmacol , vol.27 , pp. 838-844
    • Yang, R.1    Thomas, G.2    Bunting, S.3
  • 64
    • 34548141828 scopus 로고    scopus 로고
    • Arterial thromboembolic events in patients with metastatic carcinoma treated with chemotherapy and bevacizumab
    • Scappaticci F.A., Skillings J.R., Holden S.N., et al. Arterial thromboembolic events in patients with metastatic carcinoma treated with chemotherapy and bevacizumab. J Natl Cancer Inst 99 (2007) 1232-1239
    • (2007) J Natl Cancer Inst , vol.99 , pp. 1232-1239
    • Scappaticci, F.A.1    Skillings, J.R.2    Holden, S.N.3
  • 65
    • 0042343801 scopus 로고    scopus 로고
    • Randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer
    • Yang J.C., Haworth L., Sherry R.M., et al. Randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer. N Engl J Med 349 (2003) 427-434
    • (2003) N Engl J Med , vol.349 , pp. 427-434
    • Yang, J.C.1    Haworth, L.2    Sherry, R.M.3
  • 66
    • 0038327794 scopus 로고    scopus 로고
    • Efficacy and toxicity of the angiogenesis inhibitor SU5416 as a single agent in patients with advanced renal cell carcinoma, melanoma, and soft tissue sarcoma
    • Kuenen B.C., Tabernero J., and Baselga J. Efficacy and toxicity of the angiogenesis inhibitor SU5416 as a single agent in patients with advanced renal cell carcinoma, melanoma, and soft tissue sarcoma. Clin Cancer Res 9 (2003) 1648-1655
    • (2003) Clin Cancer Res , vol.9 , pp. 1648-1655
    • Kuenen, B.C.1    Tabernero, J.2    Baselga, J.3
  • 67
    • 4444250452 scopus 로고    scopus 로고
    • Phase II study of the antiangiogenic agent SU5416 in patients with advanced soft tissue sarcomas
    • Heymach J.V., Desai J., Manola J., et al. Phase II study of the antiangiogenic agent SU5416 in patients with advanced soft tissue sarcomas. Clin Cancer Res 10 (2004) 5732-5740
    • (2004) Clin Cancer Res , vol.10 , pp. 5732-5740
    • Heymach, J.V.1    Desai, J.2    Manola, J.3
  • 68
    • 0037087585 scopus 로고    scopus 로고
    • Dose-finding and pharmacokinetic study of cisplatin, gemcitabine, and SU5416 in patients with solid tumors
    • Kuenen B.C., Rosen L., Smit E.F., et al. Dose-finding and pharmacokinetic study of cisplatin, gemcitabine, and SU5416 in patients with solid tumors. J Clin Oncol 20 (2002) 1657-1667
    • (2002) J Clin Oncol , vol.20 , pp. 1657-1667
    • Kuenen, B.C.1    Rosen, L.2    Smit, E.F.3
  • 69
    • 0036738403 scopus 로고    scopus 로고
    • Analysis of coagulation cascade and endothelial cell activation during inhibition of vascular endothelial growth factor/vascular endothelial growth factor receptor pathway in cancer patients
    • Kuenen B.C., Levi M., Meijers J.C., et al. Analysis of coagulation cascade and endothelial cell activation during inhibition of vascular endothelial growth factor/vascular endothelial growth factor receptor pathway in cancer patients. Arterioscler Thromb Vasc Biol 22 (2002) 1500-1505
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 1500-1505
    • Kuenen, B.C.1    Levi, M.2    Meijers, J.C.3
  • 70
    • 0037530506 scopus 로고    scopus 로고
    • Potential role of platelets in endothelial damage observed during treatment with cisplatin, gemcitabine, and the angiogenesis inhibitor SU5416
    • Kuenen B.C., Levi N., Meijers J.C.M., et al. Potential role of platelets in endothelial damage observed during treatment with cisplatin, gemcitabine, and the angiogenesis inhibitor SU5416. J Clin Oncol 21 (2003) 2192-2198
    • (2003) J Clin Oncol , vol.21 , pp. 2192-2198
    • Kuenen, B.C.1    Levi, N.2    Meijers, J.C.M.3
  • 71
    • 33644847440 scopus 로고    scopus 로고
    • Safety, pharmacokinetic, and antitumor activity of SU11248, a novel oral multitarget tyrosine kinase inhibitor, in patients with cancer
    • Faivre S., Delbaldo C., Vera K., et al. Safety, pharmacokinetic, and antitumor activity of SU11248, a novel oral multitarget tyrosine kinase inhibitor, in patients with cancer. J Clin Oncol 24 (2006) 25-35
    • (2006) J Clin Oncol , vol.24 , pp. 25-35
    • Faivre, S.1    Delbaldo, C.2    Vera, K.3
  • 72
    • 33749505836 scopus 로고    scopus 로고
    • Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial
    • Demetri G.D., van Oosterom A.T., Garrett C.R., et al. Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial. Lancet 368 (2006) 1329-1338
    • (2006) Lancet , vol.368 , pp. 1329-1338
    • Demetri, G.D.1    van Oosterom, A.T.2    Garrett, C.R.3
  • 73
    • 33846181370 scopus 로고    scopus 로고
    • Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
    • Motzer R.J., Hutson T.E., Tomczak P., et al. Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N Engl J Med 356 (2007) 115-124
    • (2007) N Engl J Med , vol.356 , pp. 115-124
    • Motzer, R.J.1    Hutson, T.E.2    Tomczak, P.3
  • 74
    • 36048992408 scopus 로고    scopus 로고
    • Phase II trial of sunitinib in patients with metastatic colorectal cancer after failure of standard therapy
    • Saltz L.B., Rosen L.S., Marshall J.L., et al. Phase II trial of sunitinib in patients with metastatic colorectal cancer after failure of standard therapy. J Clin Oncol 25 (2007) 4793-4799
    • (2007) J Clin Oncol , vol.25 , pp. 4793-4799
    • Saltz, L.B.1    Rosen, L.S.2    Marshall, J.L.3
  • 75
    • 39149120621 scopus 로고    scopus 로고
    • Multicenter, phase II trial of sunitinib in previously treated, advanced non-small-cell lung cancer
    • Socinski M.A., Novello S., Brahmer J.R., et al. Multicenter, phase II trial of sunitinib in previously treated, advanced non-small-cell lung cancer. J Clin Oncol 26 (2008) 650-656
    • (2008) J Clin Oncol , vol.26 , pp. 650-656
    • Socinski, M.A.1    Novello, S.2    Brahmer, J.R.3
  • 76
    • 27144527372 scopus 로고    scopus 로고
    • Phase I study to determine the safety and pharmacokinetics of the novel Raf kinase and VEGFR inhibitor BAY 43-9006, administered for 28 days on/7 days off in patients with advanced, refractory solid tumors
    • Moore M., Hirte H.W., Siu L., et al. Phase I study to determine the safety and pharmacokinetics of the novel Raf kinase and VEGFR inhibitor BAY 43-9006, administered for 28 days on/7 days off in patients with advanced, refractory solid tumors. Ann Oncol 16 (2005) 1688-1694
    • (2005) Ann Oncol , vol.16 , pp. 1688-1694
    • Moore, M.1    Hirte, H.W.2    Siu, L.3
  • 77
    • 33744984843 scopus 로고    scopus 로고
    • Phase II placebo-controlled randomized discontinuation trial of sorafenib in patients with metastatic renal cell carcinoma
    • Ratain M.J., Eisen T., Stadler W.M., et al. Phase II placebo-controlled randomized discontinuation trial of sorafenib in patients with metastatic renal cell carcinoma. J Clin Oncol 24 (2006) 2505-2512
    • (2006) J Clin Oncol , vol.24 , pp. 2505-2512
    • Ratain, M.J.1    Eisen, T.2    Stadler, W.M.3
  • 78
    • 33749017926 scopus 로고    scopus 로고
    • Phase II study of sorafenib in patients with advanced hepatocellular carcinoma
    • Abou-Alfa G.K., Schwartz L., Ricci S., et al. Phase II study of sorafenib in patients with advanced hepatocellular carcinoma. J Clin Oncol 24 (2006) 4293-4300
    • (2006) J Clin Oncol , vol.24 , pp. 4293-4300
    • Abou-Alfa, G.K.1    Schwartz, L.2    Ricci, S.3
  • 79
    • 33846148701 scopus 로고    scopus 로고
    • Sorafenib in advanced clear-cell renal-cell carcinoma
    • Escudier B., Eisen T., Stadler W.M., et al., TARGET Study Group. Sorafenib in advanced clear-cell renal-cell carcinoma. N Engl J Med 356 (2007) 125-134
    • (2007) N Engl J Med , vol.356 , pp. 125-134
    • Escudier, B.1    Eisen, T.2    Stadler, W.M.3
  • 80
    • 33646204716 scopus 로고    scopus 로고
    • Results of a Phase I trial of sorafenib (BAY 43-9006) in combination with doxorubicin in patients with refractory solid tumors
    • Richly H., Henning B.F., Kupsch P., et al. Results of a Phase I trial of sorafenib (BAY 43-9006) in combination with doxorubicin in patients with refractory solid tumors. Ann Oncol 17 (2006) 866-873
    • (2006) Ann Oncol , vol.17 , pp. 866-873
    • Richly, H.1    Henning, B.F.2    Kupsch, P.3
  • 81
    • 31544460436 scopus 로고    scopus 로고
    • Phase I trial of sorafenib and gemcitabine in advanced solid tumors with an expanded cohort in advanced pancreatic cancer
    • Siu L.L., Awada A., Takimoto C.H., et al. Phase I trial of sorafenib and gemcitabine in advanced solid tumors with an expanded cohort in advanced pancreatic cancer. Clin Cancer Res 12 (2006) 144-151
    • (2006) Clin Cancer Res , vol.12 , pp. 144-151
    • Siu, L.L.1    Awada, A.2    Takimoto, C.H.3
  • 82
    • 20444473802 scopus 로고    scopus 로고
    • Phase I clinical and pharmacokinetic study of PTK/ZK, a multiple VEGF receptor inhibitor, in patients with liver metastases from solid tumours
    • Mross K., Drevs J., Müller M., et al. Phase I clinical and pharmacokinetic study of PTK/ZK, a multiple VEGF receptor inhibitor, in patients with liver metastases from solid tumours. Eur J Cancer 41 (2005) 1291-1299
    • (2005) Eur J Cancer , vol.41 , pp. 1291-1299
    • Mross, K.1    Drevs, J.2    Müller, M.3
  • 83
    • 23044432756 scopus 로고    scopus 로고
    • Phase I study of the safety, tolerability, pharmacokinetics, and pharmacodynamics of PTK787/ZK 222584 administered twice daily in patients with advanced cancer
    • Thomas A.L., Morgan B., Horsfield M.A., et al. Phase I study of the safety, tolerability, pharmacokinetics, and pharmacodynamics of PTK787/ZK 222584 administered twice daily in patients with advanced cancer. J Clin Oncol 23 (2005) 4162-4171
    • (2005) J Clin Oncol , vol.23 , pp. 4162-4171
    • Thomas, A.L.1    Morgan, B.2    Horsfield, M.A.3
  • 84
    • 37849009384 scopus 로고    scopus 로고
    • Phase II, open-label study of PTK787/ZK222584 for the treatment of metastatic gastrointestinal stromal tumors resistant to imatinib mesylate
    • Joensuu H., De Braud F., Coco P., et al. Phase II, open-label study of PTK787/ZK222584 for the treatment of metastatic gastrointestinal stromal tumors resistant to imatinib mesylate. Ann Oncol 19 (2008) 173-177
    • (2008) Ann Oncol , vol.19 , pp. 173-177
    • Joensuu, H.1    De Braud, F.2    Coco, P.3
  • 85
    • 33947182049 scopus 로고    scopus 로고
    • Vatalanib: the clinical development of a tyrosine kinase inhibitor of angiogenesis in solid tumours
    • Scott E.N., Meinhardt G., Jacques C., et al. Vatalanib: the clinical development of a tyrosine kinase inhibitor of angiogenesis in solid tumours. Exp Opin Investig Drugs 16 (2007) 367-379
    • (2007) Exp Opin Investig Drugs , vol.16 , pp. 367-379
    • Scott, E.N.1    Meinhardt, G.2    Jacques, C.3
  • 86
    • 21844464600 scopus 로고    scopus 로고
    • Vatalanib (PTK787/ZK 222584) in combination with FOLFOX4 versus FOLFOX4 alone as first-line treatment for colorectal cancer: preliminary results from the CONFIRM-1 trial
    • Tyagi P. Vatalanib (PTK787/ZK 222584) in combination with FOLFOX4 versus FOLFOX4 alone as first-line treatment for colorectal cancer: preliminary results from the CONFIRM-1 trial. Clin Colorectal Cancer 5 (2005) 24-26
    • (2005) Clin Colorectal Cancer , vol.5 , pp. 24-26
    • Tyagi, P.1
  • 87
    • 0142029001 scopus 로고    scopus 로고
    • Venous thromboembolism among patients with advanced lung cancer randomized to prinomastat or placebo, plus chemotherapy
    • Behrendt C.E., and Ruiz R.B. Venous thromboembolism among patients with advanced lung cancer randomized to prinomastat or placebo, plus chemotherapy. Thromb Haemost 90 (2003) 734-737
    • (2003) Thromb Haemost , vol.90 , pp. 734-737
    • Behrendt, C.E.1    Ruiz, R.B.2
  • 88
    • 20044388325 scopus 로고    scopus 로고
    • Phase III study of matrix metalloproteinase inhibitor prinomastat in non-small-cell lung cancer
    • Bissett D., O'Byrne K.J., von Pawel J., et al. Phase III study of matrix metalloproteinase inhibitor prinomastat in non-small-cell lung cancer. J Clin Oncol 23 (2005) 842-849
    • (2005) J Clin Oncol , vol.23 , pp. 842-849
    • Bissett, D.1    O'Byrne, K.J.2    von Pawel, J.3
  • 89
    • 33646594999 scopus 로고    scopus 로고
    • Phase II, parallel-design study of preoperative combined modalità therapy and the matrix metalloprotease (mmp) inhibitor prinomastat in patients with esophageal adenocarcinoma
    • Heath E.I., Burtness B.A., Kleinberg L., et al. Phase II, parallel-design study of preoperative combined modalità therapy and the matrix metalloprotease (mmp) inhibitor prinomastat in patients with esophageal adenocarcinoma. Invest New Drugs 24 (2006) 135-140
    • (2006) Invest New Drugs , vol.24 , pp. 135-140
    • Heath, E.I.1    Burtness, B.A.2    Kleinberg, L.3
  • 90
    • 0141566695 scopus 로고    scopus 로고
    • A phase I/IIA trial of continuous five-day infusion of squalamine lactate (MSI-1256F) plus carboplatin and paclitaxel in patients with advanced non-small cell lung cancer
    • Herbst R.S., Hammond L.A., Carbone D.P., et al. A phase I/IIA trial of continuous five-day infusion of squalamine lactate (MSI-1256F) plus carboplatin and paclitaxel in patients with advanced non-small cell lung cancer. Clin Cancer Res 9 (2003) 4108-4115
    • (2003) Clin Cancer Res , vol.9 , pp. 4108-4115
    • Herbst, R.S.1    Hammond, L.A.2    Carbone, D.P.3
  • 91
    • 0037106261 scopus 로고    scopus 로고
    • Phase I study of recombinant human endostatin in patients with advanced solid tumors
    • Herbst R.S., Hess K.R., Tran H.T., et al. Phase I study of recombinant human endostatin in patients with advanced solid tumors. J Clin Oncol 20 (2002) 3792-3803
    • (2002) J Clin Oncol , vol.20 , pp. 3792-3803
    • Herbst, R.S.1    Hess, K.R.2    Tran, H.T.3
  • 92
    • 33645732100 scopus 로고    scopus 로고
    • Phase I clinical evaluation of weekly administration of the novel vascular-targeting agent, ZD6126, in patients with solid tumors
    • Beerepoot L.V., Radema S.A., Witteveen E.O., et al. Phase I clinical evaluation of weekly administration of the novel vascular-targeting agent, ZD6126, in patients with solid tumors. J Clin Oncol 24 (2006) 1491-1498
    • (2006) J Clin Oncol , vol.24 , pp. 1491-1498
    • Beerepoot, L.V.1    Radema, S.A.2    Witteveen, E.O.3
  • 93
    • 36849070772 scopus 로고    scopus 로고
    • American Society of Clinical Oncology guideline: recommendations for venous thromboembolism prophylaxis and treatment in patients with cancer
    • Lyman G.H., Khorana A.A., Falanga A., et al., American Society of Clinical Oncology. American Society of Clinical Oncology guideline: recommendations for venous thromboembolism prophylaxis and treatment in patients with cancer. J Clin Oncol 25 (2007) 5490-5505
    • (2007) J Clin Oncol , vol.25 , pp. 5490-5505
    • Lyman, G.H.1    Khorana, A.A.2    Falanga, A.3
  • 94
    • 46049090201 scopus 로고    scopus 로고
    • Prevention of venous thromboembolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)
    • Geerts W.H., Bergqvist D., Pineo G.F., et al., American College of Chest Physicians. Prevention of venous thromboembolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 133 Suppl. (2008) 381S-453S
    • (2008) Chest , vol.133 , Issue.SUPPL
    • Geerts, W.H.1    Bergqvist, D.2    Pineo, G.F.3
  • 95
    • 19944368366 scopus 로고    scopus 로고
    • Prevention of venous thromboembolism with low molecular-weight heparin in patients with multiple myeloma treated with thalidomide and chemotherapy
    • Minnema M.C., Breitkreutz I., Auwerda J.J., et al. Prevention of venous thromboembolism with low molecular-weight heparin in patients with multiple myeloma treated with thalidomide and chemotherapy. Leukemia 18 (2004) 2044-2046
    • (2004) Leukemia , vol.18 , pp. 2044-2046
    • Minnema, M.C.1    Breitkreutz, I.2    Auwerda, J.J.3
  • 96
    • 3242760702 scopus 로고    scopus 로고
    • First-line therapy with thalidomide and dexamethasone in preparation for autologous stem cell transplantation for multiple myeloma
    • Cavo M., Zamagni E., Tosi P., et al. First-line therapy with thalidomide and dexamethasone in preparation for autologous stem cell transplantation for multiple myeloma. Haematologica 89 (2004) 826-831
    • (2004) Haematologica , vol.89 , pp. 826-831
    • Cavo, M.1    Zamagni, E.2    Tosi, P.3
  • 97
    • 28544436819 scopus 로고    scopus 로고
    • The role of aspirin in the prevention of thrombotic complications of thalidomide and anthracycline-based chemotherapy for multiple myeloma
    • Baz R., Li L., Kottke-Marchant K., et al. The role of aspirin in the prevention of thrombotic complications of thalidomide and anthracycline-based chemotherapy for multiple myeloma. Mayo Clin Proc 80 (2005) 1568-1574
    • (2005) Mayo Clin Proc , vol.80 , pp. 1568-1574
    • Baz, R.1    Li, L.2    Kottke-Marchant, K.3
  • 98
    • 28644432332 scopus 로고    scopus 로고
    • Combining angiogenesis inhibitors with cytotoxic chemotherapy enhances PSA response in hormone refractory prostate cancer (HRPC), a randomized study of weekly docetaxel alone or in combination with thalidomide
    • (Abstract 1725)
    • Salimichokami M. Combining angiogenesis inhibitors with cytotoxic chemotherapy enhances PSA response in hormone refractory prostate cancer (HRPC), a randomized study of weekly docetaxel alone or in combination with thalidomide. Proc Am Soc Clin Oncol 22 (2003) 429 (Abstract 1725)
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 429
    • Salimichokami, M.1
  • 99
    • 33645351051 scopus 로고    scopus 로고
    • Safety of low-dose aspirin (ASA) in a pooled analysis of 3 randomized, controlled trials (RCTs) of bevacizumab (BV) with chemotherapy (CT) in patients (pts) with metastatic colorectal cancer (mCRC). ASCO Annual Meeting Proceedings
    • Hambleton J., Skillings J., Kabbinavar F., et al. Safety of low-dose aspirin (ASA) in a pooled analysis of 3 randomized, controlled trials (RCTs) of bevacizumab (BV) with chemotherapy (CT) in patients (pts) with metastatic colorectal cancer (mCRC). ASCO Annual Meeting Proceedings. J Clin Oncol 23 Suppl. (2005) 3554
    • (2005) J Clin Oncol , vol.23 , Issue.SUPPL , pp. 3554
    • Hambleton, J.1    Skillings, J.2    Kabbinavar, F.3
  • 100
    • 18744380623 scopus 로고    scopus 로고
    • Bevacizumab does not increase bleeding in patients with metastatic colorectal cancer receiving concurrent anticoagulation. ASCO Annual Meeting Proceedings (Post-Meeting Edition)
    • Hambleton J., Novotny W.F., Hurwitz H., et al. Bevacizumab does not increase bleeding in patients with metastatic colorectal cancer receiving concurrent anticoagulation. ASCO Annual Meeting Proceedings (Post-Meeting Edition). J Clin Oncol 22 Suppl. (2004) 3528
    • (2004) J Clin Oncol , vol.22 , Issue.SUPPL , pp. 3528
    • Hambleton, J.1    Novotny, W.F.2    Hurwitz, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.