Elucidation of the substrate specificity, kinetic and catalytic mechanism of adenylosuccinate lyase from Plasmodium falciparum

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1794, Issue 4, 2009, Pages 642-654

  Bulusu, Vinay ^a   Srinivasan, Bharath ^a   Bopanna, Monnanda Ponnappa ^a   Balaram, Hemalatha ^a  

^a JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH   (India)

Author keywords

Adenylosuccinate lyase; AICAR; Catalysis; Plasmodium falciparum; Rapid equilibrium

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; ADENYLOSUCCINATE LYASE; SERINE;

ARTICLE; CATALYSIS; ENZYME ANALYSIS; ENZYME SPECIFICITY; ENZYME STRUCTURE; IONIZATION; KINETICS; PH MEASUREMENT; PLASMODIUM FALCIPARUM; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; SITE DIRECTED MUTAGENESIS; THERMODYNAMICS; WESTERN BLOTTING;

ADENOSINE MONOPHOSPHATE; ADENYLOSUCCINATE LYASE; AMINO ACID SEQUENCE; AMINOIMIDAZOLE CARBOXAMIDE; ANIMALS; BIOCATALYSIS; CYCLIC AMP; ESCHERICHIA COLI; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS; RECOMBINANT PROTEINS; RIBONUCLEOTIDES; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY; THERMODYNAMICS;

PLASMODIUM FALCIPARUM;

EID: 61649117504     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2008.11.021     Document Type: Article

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