ISN1 nucleotidases and HAD superfamily protein fold: In silico sequence and structure analysis

In Silico Biology

Volumn 7, Issue 2, 2007, Pages 187-193

  Srinivasan, Bharath ^a   Balaram, Hemalatha ^a  

^a JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH   (India)

Author keywords

Distant homology modeling; HAD superfamily; ISN1 nucleotidase; Phylogenetic analysis; Purine nucleotidase

Indexed keywords

GUANOSINE PHOSPHATE; HALOACID DEHALOGENASE; HYDROLASE; IMP SPECIFIC 5' NUCLEOTIDASE 1; INOSINE PHOSPHATE; NUCLEOTIDASE; UNCLASSIFIED DRUG;

ARTICLE; COMPUTER MODEL; CONTROLLED STUDY; ENZYME SPECIFICITY; ENZYME STRUCTURE; FUNGUS; HUMAN; MOLECULAR EVOLUTION; MOLECULAR PHYLOGENY; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMODIUM; PROTEIN FAMILY; PROTEIN FOLDING; PROTEIN MOTIF; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS; YEAST;

5'-NUCLEOTIDASE; COMPUTATIONAL BIOLOGY; EVOLUTION, MOLECULAR; HYDROLASES; MODELS, MOLECULAR; MULTIGENE FAMILY; PEPTIDE FRAGMENTS; PHYLOGENY; PROTEIN CONFORMATION; PROTEIN FOLDING; SACCHAROMYCES CEREVISIAE; SEQUENCE ALIGNMENT;

EID: 34548356520     PISSN: 13866338     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Allen, K. N. and Dunaway-Mariano, D. (2004). Phosphoryl group transfer: evolution of a catalytic scaffold. Trends Biochem. Sci. 29, 495-503.
2. Altschul, S. F., Madden, T. L., Schf̈fer, A. A., Zhang, J., Zhang, Z., Miller, W. and Lipman, D. J. (1997). Gapped BLAST and PSI-BLAST: A new generation of protein database search programs. Nucleic Acids Res. 25 3389-3402.
3. Bretonnet, A. S., Jordheim, L. P., Dumontet, C. and Lancelin, J. M. (2005). Regulation and activity of cytosolic 5′-nucleotidase II. A bifunctional allosteric enzyme of the Haloacid Dehalogenase superfamily involved in cellular metabolism. FEBS Lett. 579, 3363-3368.
4. Edgar, R. C.(2004). MUSCLE: Multiple sequence alignment with high accuracy and high throughput. Nucleic Acids Res. 32, 1792-1797.
5. Hunsucker, S. A., Mitchell, B. S. and Spychala, J. (2005). The 5′-nucleotidases as regulators of nucleotide and drug metabolism. Pharmacol. Ther. 107, 1-30.
6. Itoh, R., Saint-Marc, C., Chaignepain, S., Katahira, R., Schmitter, J.-M. and Daignan-Fornier, B. (2003). The yeast ISN1 (YOR155c) gene encodes a new type of IMP-specific 5′-nucleotidase. BMC Biochem. 4, 4.
7. Jones, D. T. (1999). GenTHREADER: An efficient and reliable protein fold recognition method for genomic sequences. J. Mol. Biol. 287, 797-815.
8. Kumar, S., Tamura, K. and Nei, M. (2004). MEGA3: Integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment. Brief. Bioinform. 5, 150-163.
9. Lu, Z., Dunaway-Mariano, D. and Allen, K. N. (2005). HAD superfamily phosphotransferase substrate diversification: Structure and function analysis of HAD subclass IIB sugar phosphatase BT4131. Biochemistry 44, 8684-8696.
10. Notredame, C., Higgins, D. G. and Heringa, J. (2000). T-Coffee: A novel method for fast and accurate multiple sequence alignment. J. Mol. Biol. 302, 205-217.
11. Zhang, G., Morais, M. C., Dai, J., Zhang, W., Dunaway-Mariano, D. and Allen, K. N. (2004). Investigation of metal ion binding in phosphonoacetaldehyde hydrolase identifies sequence markers for metal-activated enzymes of the HAD enzyme supertamily. Biochemistry 43, 4990-4997.