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Volumn 238, Issue 3, 2009, Pages 581-594

Mouse mutagenesis identifies novel roles for left-right patterning genes in pulmonary, craniofacial, ocular, and limb development

Author keywords

Cilia; ENU; Left right; Mouse; Pulmonary

Indexed keywords

DYNEIN ADENOSINE TRIPHOSPHATASE; ETHYLNITROSOUREA;

EID: 61649114214     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.21874     Document Type: Article
Times cited : (34)

References (58)
  • 1
    • 0023658298 scopus 로고
    • 5′ cleavage site in eukaryotic pre-mRNA splicing is determined by the overall 5′ splice region, not by the conserved 5′ GU
    • Aebi M, Hornig H, Weissmann C. 1987. 5′ cleavage site in eukaryotic pre-mRNA splicing is determined by the overall 5′ splice region, not by the conserved 5′ GU. Cell 50:237-246.
    • (1987) Cell , vol.50 , pp. 237-246
    • Aebi, M.1    Hornig, H.2    Weissmann, C.3
  • 2
    • 0035879412 scopus 로고    scopus 로고
    • Clinical aspects of defects in the determination of laterality
    • Aylsworth AS. 2001. Clinical aspects of defects in the determination of laterality. Am J Med Genet 101:345-355.
    • (2001) Am J Med Genet , vol.101 , pp. 345-355
    • Aylsworth, A.S.1
  • 4
    • 0029873599 scopus 로고    scopus 로고
    • Cell proliferation in mammalian gastrulation: The ventral node and notochord are relatively quiescent
    • Bellomo D, Lander A, Harragan I, Brown NA. 1996. Cell proliferation in mammalian gastrulation: the ventral node and notochord are relatively quiescent. Dev Dyn 205:471-485.
    • (1996) Dev Dyn , vol.205 , pp. 471-485
    • Bellomo, D.1    Lander, A.2    Harragan, I.3    Brown, N.A.4
  • 6
    • 0029993646 scopus 로고    scopus 로고
    • Relationship between asymmetric nodal expression and the direction of embryonic turning [see comments]
    • Collignon J, Varlet I, Robertson EJ. 1996. Relationship between asymmetric nodal expression and the direction of embryonic turning [see comments]. Nature 381:155-158.
    • (1996) Nature , vol.381 , pp. 155-158
    • Collignon, J.1    Varlet, I.2    Robertson, E.J.3
  • 10
    • 29444439981 scopus 로고    scopus 로고
    • Oral-facial-digital type I protein is required for primary cilia formation and left-right axis specification
    • Ferrante MI, Zullo A, Barra A, Bimonte S, Messaddeq N, Studer M, Dolle P, Franco B. 2006. Oral-facial-digital type I protein is required for primary cilia formation and left-right axis specification. Nat Genet 38:112-117.
    • (2006) Nat Genet , vol.38 , pp. 112-117
    • Ferrante, M.I.1    Zullo, A.2    Barra, A.3    Bimonte, S.4    Messaddeq, N.5    Studer, M.6    Dolle, P.7    Franco, B.8
  • 12
    • 40749144679 scopus 로고    scopus 로고
    • Gli2 and gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function
    • Haycraft CJ, Banizs B, Aydin-Son Y, Zhang Q, Michaud EJ, Yoder BK. 2005. Gli2 and gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function. PLoS Genet 1:e53.
    • (2005) PLoS Genet , vol.1
    • Haycraft, C.J.1    Banizs, B.2    Aydin-Son, Y.3    Zhang, Q.4    Michaud, E.J.5    Yoder, B.K.6
  • 14
    • 0022369586 scopus 로고
    • Dose-repetition increases the mutagenic effectiveness of N-ethyl-N-nitrosourea in mouse spermatogonia
    • Hitotsumachi S, Carpenter DA, Russell WL. 1985. Dose-repetition increases the mutagenic effectiveness of N-ethyl-N-nitrosourea in mouse spermatogonia. Proc Natl Acad Sci U S A 82:6619-6621.
    • (1985) Proc Natl Acad Sci U S A , vol.82 , pp. 6619-6621
    • Hitotsumachi, S.1    Carpenter, D.A.2    Russell, W.L.3
  • 15
    • 0034425715 scopus 로고    scopus 로고
    • Hrabe de Angelis MH, Flaswinkel H, Fuchs H, Rathkolb B, Soewarto D, Marschall S, Heffner S, Pargent W, Wuensch K, Jung M, Reis A, Richter T, Alessandrini F, Jakob T, Fuchs E, Kolb H, Kremmer E, Schaeble K, Rollinski B, Roscher A, Peters C, Meitinger T, Strom T, Steckler T, Holsboer F, Klopstock T, Gekeler F, Schindewolf C, Jung T, Avraham K, Behrendt H, Ring J, Zimmer A, Schughart K, Pfeffer K, Wolf E, Balling R. 2000. Genome-wide, large-scale production of mutant mice by ENU mutagenesis. Nat Genet 25:444-447.
    • Hrabe de Angelis MH, Flaswinkel H, Fuchs H, Rathkolb B, Soewarto D, Marschall S, Heffner S, Pargent W, Wuensch K, Jung M, Reis A, Richter T, Alessandrini F, Jakob T, Fuchs E, Kolb H, Kremmer E, Schaeble K, Rollinski B, Roscher A, Peters C, Meitinger T, Strom T, Steckler T, Holsboer F, Klopstock T, Gekeler F, Schindewolf C, Jung T, Avraham K, Behrendt H, Ring J, Zimmer A, Schughart K, Pfeffer K, Wolf E, Balling R. 2000. Genome-wide, large-scale production of mutant mice by ENU mutagenesis. Nat Genet 25:444-447.
  • 16
    • 77957211015 scopus 로고
    • Visceral inversion and associated anomalies in the mouse
    • Hummel KP, Chapman DB. 1955. Visceral inversion and associated anomalies in the mouse. J Hered 50:9-13.
    • (1955) J Hered , vol.50 , pp. 9-13
    • Hummel, K.P.1    Chapman, D.B.2
  • 17
    • 1642564276 scopus 로고    scopus 로고
    • To beat or not to beat: Roles of cilia in development and disease
    • Ibanez-Tallon I, Heintz N, Omran H. 2003. To beat or not to beat: roles of cilia in development and disease. Hum Mol Genet 12 Spec No 1:R27-R35.
    • (2003) Hum Mol Genet , vol.12 , Issue.SPEC 1
    • Ibanez-Tallon, I.1    Heintz, N.2    Omran, H.3
  • 18
    • 0035577854 scopus 로고    scopus 로고
    • Hedgehog signaling in animal development: Paradigms and principles
    • Ingham PW, McMahon AP. 2001. Hedgehog signaling in animal development: paradigms and principles. Genes Dev 15:3059-3087.
    • (2001) Genes Dev , vol.15 , pp. 3059-3087
    • Ingham, P.W.1    McMahon, A.P.2
  • 19
    • 0025836071 scopus 로고
    • A reappraisal of non-consensus mRNA splice sites
    • Jackson IJ. 1991. A reappraisal of non-consensus mRNA splice sites. Nucleic Acids Res 19:3795-3798.
    • (1991) Nucleic Acids Res , vol.19 , pp. 3795-3798
    • Jackson, I.J.1
  • 21
    • 0035025182 scopus 로고    scopus 로고
    • The VACTERL association: Lessons from the Sonic hedgehog pathway
    • Kim J, Kim P, Hui CC. 2001. The VACTERL association: lessons from the Sonic hedgehog pathway. Clin Genet 59:306-315.
    • (2001) Clin Genet , vol.59 , pp. 306-315
    • Kim, J.1    Kim, P.2    Hui, C.C.3
  • 23
    • 0017050268 scopus 로고
    • Random determination of a developmental process: Reversal of normal visceral asymmetry in the mouse
    • Layton WM Jr. 1976. Random determination of a developmental process: reversal of normal visceral asymmetry in the mouse. J Hered 67:336-338.
    • (1976) J Hered , vol.67 , pp. 336-338
    • Layton Jr., W.M.1
  • 24
    • 9944241753 scopus 로고    scopus 로고
    • Left-right asymmetry in embryonic development: A comprehensive review
    • Levin M. 2005. Left-right asymmetry in embryonic development: a comprehensive review. Mech Dev 122:3-25.
    • (2005) Mech Dev , vol.122 , pp. 3-25
    • Levin, M.1
  • 25
    • 0031711075 scopus 로고    scopus 로고
    • Sonic hedgehog is essential to foregut development
    • Litingtung Y, Lei L, Westphal H, Chiang C. 1998. Sonic hedgehog is essential to foregut development. Nat Genet 20:58-61.
    • (1998) Nat Genet , vol.20 , pp. 58-61
    • Litingtung, Y.1    Lei, L.2    Westphal, H.3    Chiang, C.4
  • 26
    • 23144466931 scopus 로고    scopus 로고
    • Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors
    • Liu A, Wang B, Niswander LA. 2005. Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors. Development 132:3103-3111.
    • (2005) Development , vol.132 , pp. 3103-3111
    • Liu, A.1    Wang, B.2    Niswander, L.A.3
  • 27
    • 0033609103 scopus 로고    scopus 로고
    • Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II
    • Marszalek JR, Ruiz-Lozano P, Roberts E, Chien KR, Goldstein LS. 1999. Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II. Proc Natl Acad Sci U S A 96:5043-5048.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 5043-5048
    • Marszalek, J.R.1    Ruiz-Lozano, P.2    Roberts, E.3    Chien, K.R.4    Goldstein, L.S.5
  • 28
    • 0038784537 scopus 로고    scopus 로고
    • Two populations of node monocilia initiate left-right asymmetry in the mouse
    • McGrath J, Somlo S, Makova S, Tian X, Brueckner M. 2003. Two populations of node monocilia initiate left-right asymmetry in the mouse. Cell 114:61-73.
    • (2003) Cell , vol.114 , pp. 61-73
    • McGrath, J.1    Somlo, S.2    Makova, S.3    Tian, X.4    Brueckner, M.5
  • 30
    • 0028213962 scopus 로고
    • Complex asparagine-linked oligosaccharides are required for morphogenic events during post-implantation development
    • Metzler M, Gertz A, Sarkar M, Schachter H, Schrader JW, Marth JD. 1994. Complex asparagine-linked oligosaccharides are required for morphogenic events during post-implantation development. EMBO J 13:2056-2065.
    • (1994) EMBO J , vol.13 , pp. 2056-2065
    • Metzler, M.1    Gertz, A.2    Sarkar, M.3    Schachter, H.4    Schrader, J.W.5    Marth, J.D.6
  • 31
    • 0031683165 scopus 로고    scopus 로고
    • Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus
    • Motoyama J, Liu J, Mo R, Ding Q, Post M, Hui CC. 1998. Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus. Nat Genet 20:54-57.
    • (1998) Nat Genet , vol.20 , pp. 54-57
    • Motoyama, J.1    Liu, J.2    Mo, R.3    Ding, Q.4    Post, M.5    Hui, C.C.6
  • 33
    • 0034425410 scopus 로고    scopus 로고
    • Nolan PM, Peters J, Strivens M, Rogers D, Hagan J, Spurr N, Gray IC, Vizor L, Brooker D, Whitehill E, Washbourne R, Hough T, Greenaway S, Hewitt M, Liu X, McCormack S, Pickford K, Selley R, Wells C, Tymowska-Lalanne Z, Roby P, Glenister P, Thornton C, Thaung C, Stevenson JA, Arkell R, Mburu P, Hardisty R, Kiernan A, Erven A, Steel KP, Voegeling S, Guenet JL, Nickols C, Sadri R, Nasse M, Isaacs A, Davies K, Browne M, Fisher EM, Martin J, Rastan S, Brown SD, Hunter J. 2000. A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse. Nat Genet 25:440-443.
    • Nolan PM, Peters J, Strivens M, Rogers D, Hagan J, Spurr N, Gray IC, Vizor L, Brooker D, Whitehill E, Washbourne R, Hough T, Greenaway S, Hewitt M, Liu X, McCormack S, Pickford K, Selley R, Wells C, Tymowska-Lalanne Z, Roby P, Glenister P, Thornton C, Thaung C, Stevenson JA, Arkell R, Mburu P, Hardisty R, Kiernan A, Erven A, Steel KP, Voegeling S, Guenet JL, Nickols C, Sadri R, Nasse M, Isaacs A, Davies K, Browne M, Fisher EM, Martin J, Rastan S, Brown SD, Hunter J. 2000. A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse. Nat Genet 25:440-443.
  • 34
    • 0032428685 scopus 로고    scopus 로고
    • Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein
    • Nonaka S, Tanaka Y, Okada Y, Takeda S, Harada A, Kanai Y, Kido M, Hirokawa N. 1998. Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein. Cell 95:829-837.
    • (1998) Cell , vol.95 , pp. 829-837
    • Nonaka, S.1    Tanaka, Y.2    Okada, Y.3    Takeda, S.4    Harada, A.5    Kanai, Y.6    Kido, M.7    Hirokawa, N.8
  • 36
    • 0036638778 scopus 로고    scopus 로고
    • The Foxh1-dependent autoregulatory enhancer controls the level of Nodal signals in the mouse embryo
    • Norris DP, Brennan J, Bikoff EK, Robertson EJ. 2002. The Foxh1-dependent autoregulatory enhancer controls the level of Nodal signals in the mouse embryo. Development 129:3455-3468.
    • (2002) Development , vol.129 , pp. 3455-3468
    • Norris, D.P.1    Brennan, J.2    Bikoff, E.K.3    Robertson, E.J.4
  • 39
    • 0032563948 scopus 로고    scopus 로고
    • Sonic hedgehog regulates branching morphogenesis in the mammalian lung
    • Pepicelli CV, Lewis PM, McMahon AP. 1998. Sonic hedgehog regulates branching morphogenesis in the mammalian lung. Curr Biol 8:1083-1086.
    • (1998) Curr Biol , vol.8 , pp. 1083-1086
    • Pepicelli, C.V.1    Lewis, P.M.2    McMahon, A.P.3
  • 40
    • 28244501046 scopus 로고    scopus 로고
    • Left-right asymmetry and congenital cardiac defects: Getting to the heart of the matter in vertebrate left-right axis determination
    • Ramsdell AF. 2005. Left-right asymmetry and congenital cardiac defects: getting to the heart of the matter in vertebrate left-right axis determination. Dev Biol 288:1-20.
    • (2005) Dev Biol , vol.288 , pp. 1-20
    • Ramsdell, A.F.1
  • 41
    • 0033916281 scopus 로고    scopus 로고
    • Hedgehog signals regulate multiple aspects of gastrointestinal development
    • Ramalho-Santos M, Melton DA, McMahon AP. 2000. Hedgehog signals regulate multiple aspects of gastrointestinal development. Development 127:2763-2772.
    • (2000) Development , vol.127 , pp. 2763-2772
    • Ramalho-Santos, M.1    Melton, D.A.2    McMahon, A.P.3
  • 42
    • 0032924464 scopus 로고    scopus 로고
    • N-ethyl-N-nitrosourea mutagenesis of a 6- to 11-cM subregion of the Fah-Hbb interval of mouse chromosome 7: Completed testing of 4557 gametes and deletion mapping and complementation analysis of 31 mutations
    • Rinchik EM, Carpenter DA. 1999. N-ethyl-N-nitrosourea mutagenesis of a 6- to 11-cM subregion of the Fah-Hbb interval of mouse chromosome 7: completed testing of 4557 gametes and deletion mapping and complementation analysis of 31 mutations. Genetics 152:373-383.
    • (1999) Genetics , vol.152 , pp. 373-383
    • Rinchik, E.M.1    Carpenter, D.A.2
  • 43
    • 16644375931 scopus 로고    scopus 로고
    • OFD1 is a centrosomal/basal body protein expressed during mesenchymal-epithelial transition in human nephrogenesis
    • Romio L, Fry AM, Winyard PJ, Malcolm S, Woolf AS, Feather SA. 2004. OFD1 is a centrosomal/basal body protein expressed during mesenchymal-epithelial transition in human nephrogenesis. J Am Soc Nephrol 15:2556-2568.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 2556-2568
    • Romio, L.1    Fry, A.M.2    Winyard, P.J.3    Malcolm, S.4    Woolf, A.S.5    Feather, S.A.6
  • 45
    • 0027183187 scopus 로고
    • A Chlamydomonas outer arm dynein mutant with a truncated beta heavy chain
    • Sakakibara H, Takada S, King SM, Witman GB, Kamiya R. 1993. A Chlamydomonas outer arm dynein mutant with a truncated beta heavy chain. J Cell Biol 122:653-661.
    • (1993) J Cell Biol , vol.122 , pp. 653-661
    • Sakakibara, H.1    Takada, S.2    King, S.M.3    Witman, G.B.4    Kamiya, R.5
  • 46
    • 33646164168 scopus 로고    scopus 로고
    • Intraflagellar transport and cilium-based signaling
    • Scholey JM, Anderson KV. 2006. Intraflagellar transport and cilium-based signaling. Cell 125:439-442.
    • (2006) Cell , vol.125 , pp. 439-442
    • Scholey, J.M.1    Anderson, K.V.2
  • 48
    • 0010753936 scopus 로고
    • Saturation germ line mutagenesis of the murine t region including a lethal allele at the quaking locus
    • Shedlovsky A, King TR, Dove WF. 1988. Saturation germ line mutagenesis of the murine t region including a lethal allele at the quaking locus. Proc Natl Acad Sci U S A 85:180-184.
    • (1988) Proc Natl Acad Sci U S A , vol.85 , pp. 180-184
    • Shedlovsky, A.1    King, T.R.2    Dove, W.F.3
  • 49
    • 33745612029 scopus 로고    scopus 로고
    • The left-right axis in the mouse: From origin to morphology
    • Shiratori H, Hamada H. 2006. The left-right axis in the mouse: from origin to morphology. Development 133:2095-2104.
    • (2006) Development , vol.133 , pp. 2095-2104
    • Shiratori, H.1    Hamada, H.2
  • 51
    • 0030656618 scopus 로고    scopus 로고
    • Mutation of an axonemal dynein affects left-right asymmetry in inversus viscerum mice
    • Supp DM, Witte DP, Potter SS, Brueckner M. 1997. Mutation of an axonemal dynein affects left-right asymmetry in inversus viscerum mice. Nature 389:963-966.
    • (1997) Nature , vol.389 , pp. 963-966
    • Supp, D.M.1    Witte, D.P.2    Potter, S.S.3    Brueckner, M.4
  • 52
    • 0033377234 scopus 로고    scopus 로고
    • Targeted deletion of the ATP binding domain of left-right dynein confirms its role in specifying development of left-right asymmetries
    • Supp DM, Brueckner M, Kuehn MR, Witte DP, Lowe LA, McGrath J, Corrales J, Potter SS. 1999. Targeted deletion of the ATP binding domain of left-right dynein confirms its role in specifying development of left-right asymmetries. Development 126:5495-5504.
    • (1999) Development , vol.126 , pp. 5495-5504
    • Supp, D.M.1    Brueckner, M.2    Kuehn, M.R.3    Witte, D.P.4    Lowe, L.A.5    McGrath, J.6    Corrales, J.7    Potter, S.S.8
  • 53
    • 0033577894 scopus 로고    scopus 로고
    • Left-right asymmetry and kinesin superfamily protein KIF3A: New insights in determination of laterality and mesoderm induction by kif3A-/- mice analysis
    • Takeda S, Yonekawa Y, Tanaka Y, Okada Y, Nonaka S, Hirokawa N. 1999. Left-right asymmetry and kinesin superfamily protein KIF3A: new insights in determination of laterality and mesoderm induction by kif3A-/- mice analysis. J Cell Biol 145:825-836.
    • (1999) J Cell Biol , vol.145 , pp. 825-836
    • Takeda, S.1    Yonekawa, Y.2    Tanaka, Y.3    Okada, Y.4    Nonaka, S.5    Hirokawa, N.6
  • 54
    • 18744406718 scopus 로고    scopus 로고
    • FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward nodal flow is critical for left-right determination
    • Tanaka Y, Okada Y, Hirokawa N. 2005. FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward nodal flow is critical for left-right determination. Nature 435:172-177.
    • (2005) Nature , vol.435 , pp. 172-177
    • Tanaka, Y.1    Okada, Y.2    Hirokawa, N.3
  • 55
    • 34249978500 scopus 로고    scopus 로고
    • Bardet-Biedl syndrome: Beyond the cilium
    • Tobin JL, Beales PL. 2007. Bardet-Biedl syndrome: beyond the cilium. Pediatr Nephrol 22:926-936.
    • (2007) Pediatr Nephrol , vol.22 , pp. 926-936
    • Tobin, J.L.1    Beales, P.L.2


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