Trafficking of a ligand-receptor complex on the growth cones as an essential step for the uptake of nerve growth factor at the distal end of the axon: A single-molecule analysis

Journal of Neuroscience

Volumn 25, Issue 9, 2005, Pages 2181-2191

  Tani, Tomomi ^a   Miyamoto, Yoshikazu ^b   Fujimori, Kazuhiro E ^c   Taguchi, Takahisa ^c   Yanagida, Toshio ^b,e   Sako, Yasushi ^b,d   Harada, Yoshie ^a,e  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^d Japan Science and Technology Agency   (Japan)

^e JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Dorsal root ganglion; Endocytosis; Fluorescent single molecule imaging; Growth cone; Nerve growth factor; Rearward actin flow

Indexed keywords

ACTIN; LATRUNCULIN B; LIGAND; NERVE GROWTH FACTOR; NERVE GROWTH FACTOR RECEPTOR;

ACIDITY; ACTIN POLYMERIZATION; ANIMAL TISSUE; ARTICLE; BINDING SITE; CHICKEN; DIFFUSION; DIFFUSION COEFFICIENT; DISSOCIATION; ENDOCYTOSIS; FLOW KINETICS; FLUORESCENCE; GROWTH CONE; LAMELLIPODIUM; MOLECULE; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; RECEPTOR BINDING; RETROGRADE NERVE FIBER TRANSPORT; SPINAL GANGLION; STIMULUS RESPONSE;

ANIMALS; AXONS; BICYCLO COMPOUNDS, HETEROCYCLIC; CARBOCYANINES; CELLS, CULTURED; CHICK EMBRYO; DIAGNOSTIC IMAGING; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ENDOCYTOSIS; GANGLIA, SPINAL; GROWTH CONES; MODELS, BIOLOGICAL; NERVE GROWTH FACTOR; NEURONS; PROTEIN TRANSPORT; PSEUDOPODIA; THIAZOLES; THIAZOLIDINES; TIME FACTORS;

EID: 14644413462     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4570-04.2005     Document Type: Article

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