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Volumn 3, Issue 1, 2009, Pages 17-25

Host molecular defense mechanisms against chlamydophila pneumoniae and genetic studies of immune-response-related genes in asthma

Author keywords

Antibiotics; Asthma; Cardiovascular disease; Chlamydophila pneumoniae; Chronic obstructive pulmonary disease (COPD); Denetic polymorphisms; Glucocorticoids; Interferon ; Nod like receptors; Respiratory infections; Severity; Toll like receptors

Indexed keywords

AZITHROMYCIN; BECLOMETASONE; CD14 ANTIGEN; DEXAMETHASONE; GAMMA INTERFERON; GLUCOCORTICOID; INTERLEUKIN 1 RECEPTOR TYPE I; INTERLEUKIN 18; LEVOFLOXACIN; NITRIC OXIDE SYNTHASE; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; SIMVASTATIN; SUPPRESSOR OF CYTOKINE SIGNALING 1; TELITHROMYCIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4;

EID: 61449196989     PISSN: 1872213X     EISSN: None     Source Type: Journal    
DOI: 10.2174/187221309787158380     Document Type: Review
Times cited : (3)

References (114)
  • 2
    • 10244250341 scopus 로고    scopus 로고
    • The immunogenetics of asthma and eczema: A new focus on the epithelium
    • Cookson W. The immunogenetics of asthma and eczema: A new focus on the epithelium. Nat Rev Immunol 2004; 4: 978-988.
    • (2004) Nat Rev Immunol , vol.4 , pp. 978-988
    • Cookson, W.1
  • 3
    • 40049088465 scopus 로고    scopus 로고
    • Dendritic cells and epithelial cells: Linking innate and adaptive immunity in asthma
    • Hammad H, Lambrecht BN. Dendritic cells and epithelial cells: Linking innate and adaptive immunity in asthma. Nat Rev Immunol 2008; 8: 193-204.
    • (2008) Nat Rev Immunol , vol.8 , pp. 193-204
    • Hammad, H.1    Lambrecht, B.N.2
  • 4
    • 37549062624 scopus 로고    scopus 로고
    • Asthma and atypical bacterial infection
    • Sutherland ER, Martin RJ. Asthma and atypical bacterial infection. Chest 2007; 132: 1962-1966.
    • (2007) Chest , vol.132 , pp. 1962-1966
    • Sutherland, E.R.1    Martin, R.J.2
  • 5
    • 0026599494 scopus 로고
    • Persistent infection with Chlamydia pneumoniae following acute respiratory illness
    • Hammerschlag MR, Chirgwin K, Roblin PM, et al. Persistent infection with Chlamydia pneumoniae following acute respiratory illness. Clin Infect Dis 1992; 14: 178-182.
    • (1992) Clin Infect Dis , vol.14 , pp. 178-182
    • Hammerschlag, M.R.1    Chirgwin, K.2    Roblin, P.M.3
  • 7
    • 0032955341 scopus 로고    scopus 로고
    • Asthma, atopy and Chlamydia pneumoniae antibodies in adults
    • Von Hertzen L, Toyryla M, Gimishanov A, et al. Asthma, atopy and Chlamydia pneumoniae antibodies in adults. Clin Exp Allergy 1999; 29: 522-528.
    • (1999) Clin Exp Allergy , vol.29 , pp. 522-528
    • Von Hertzen, L.1    Toyryla, M.2    Gimishanov, A.3
  • 8
    • 0033972782 scopus 로고    scopus 로고
    • Serological evidence of infection with Chlamydia pneumoniae is related to the severity of asthma
    • Black PN, Scicchitano R, Jenkins CR, et al. Serological evidence of infection with Chlamydia pneumoniae is related to the severity of asthma. Eur Respir J 2000; 15: 254-259.
    • (2000) Eur Respir J , vol.15 , pp. 254-259
    • Black, P.N.1    Scicchitano, R.2    Jenkins, C.R.3
  • 10
    • 0036798281 scopus 로고    scopus 로고
    • Chlamydia pneumoniae immunoglobulin A reactivation and airway inflammation in acute asthma
    • Wark PA, Johnston SL, Simpson JL, Hensley MJ, Gibson PG. Chlamydia pneumoniae immunoglobulin A reactivation and airway inflammation in acute asthma. Eur Respir J 2002; 20: 834-840.
    • (2002) Eur Respir J , vol.20 , pp. 834-840
    • Wark, P.A.1    Johnston, S.L.2    Simpson, J.L.3    Hensley, M.J.4    Gibson, P.G.5
  • 12
    • 0036739189 scopus 로고    scopus 로고
    • Role of chlamydial heat shock protein 60 in the stimulation of innate immune cells by Chlamydia pneumoniae
    • Costa CP, Kirschning CJ, Busch D, et al. Role of chlamydial heat shock protein 60 in the stimulation of innate immune cells by Chlamydia pneumoniae. Eur J Immunol 2002; 32: 2460-2470.
    • (2002) Eur J Immunol , vol.32 , pp. 2460-2470
    • Costa, C.P.1    Kirschning, C.J.2    Busch, D.3
  • 13
    • 7244251610 scopus 로고    scopus 로고
    • Heat shock protein 60 from Chlamydia pneumoniae elicits an unusual set of inflammatory responses via Toll-like receptor 2 and 4 in vivo
    • Da Costa CU, Wantia N, Kirschning CJ, et al. Heat shock protein 60 from Chlamydia pneumoniae elicits an unusual set of inflammatory responses via Toll-like receptor 2 and 4 in vivo. Eur J Immunol 2004; 34: 2874-2884.
    • (2004) Eur J Immunol , vol.34 , pp. 2874-2884
    • Da Costa, C.U.1    Wantia, N.2    Kirschning, C.J.3
  • 14
    • 42049097685 scopus 로고    scopus 로고
    • Role of toll-like receptors in immune responses to chlamydial infections
    • Joyee AG, Yang X. Role of toll-like receptors in immune responses to chlamydial infections. Curr Pharm Des 2008; 14: 593-600.
    • (2008) Curr Pharm Des , vol.14 , pp. 593-600
    • Joyee, A.G.1    Yang, X.2
  • 15
    • 42149111673 scopus 로고    scopus 로고
    • Chlamydia muridarum infection subverts dendritic cell function to promote Th2 immunity and airways hyperreactivity
    • Kaiko GE, Phipps S, Hickey DK, et al. Chlamydia muridarum infection subverts dendritic cell function to promote Th2 immunity and airways hyperreactivity. J Immunol 2008; 180: 2225-3222.
    • (2008) J Immunol , vol.180 , pp. 2225-3222
    • Kaiko, G.E.1    Phipps, S.2    Hickey, D.K.3
  • 16
    • 40049100646 scopus 로고    scopus 로고
    • Discovering susceptibility genes for asthma and allergy
    • Vercelli D. Discovering susceptibility genes for asthma and allergy. Nat Rev Immunol 2008; 8: 169-182.
    • (2008) Nat Rev Immunol , vol.8 , pp. 169-182
    • Vercelli, D.1
  • 17
    • 4344648938 scopus 로고    scopus 로고
    • CD14 and toll-like receptor 4: A link between infection and acute coronary events?
    • Arroyo-Espliguero R, Avanzas P, Jeffery S, Kaski JC. CD14 and toll-like receptor 4: A link between infection and acute coronary events? Heart 2004; 90: 983-988.
    • (2004) Heart , vol.90 , pp. 983-988
    • Arroyo-Espliguero, R.1    Avanzas, P.2    Jeffery, S.3    Kaski, J.C.4
  • 18
    • 14044268789 scopus 로고    scopus 로고
    • Nod1-mediated endothelial cell activation by Chlamydophila pneumoniae
    • Opitz B, Forster S, Hocke AC, et al. Nod1-mediated endothelial cell activation by Chlamydophila pneumoniae. Circ Res 2005; 96: 319-326.
    • (2005) Circ Res , vol.96 , pp. 319-326
    • Opitz, B.1    Forster, S.2    Hocke, A.C.3
  • 19
    • 0034193992 scopus 로고    scopus 로고
    • Regulation and role of IFN-gamma in the innate resistance to infection with Chlamydia pneumoniae
    • Rottenberg ME, Gigliotti Rothfuchs A, Gigliotti D, et al. Regulation and role of IFN-gamma in the innate resistance to infection with Chlamydia pneumoniae. J Immunol 2000; 164: 4812-4818.
    • (2000) J Immunol , vol.164 , pp. 4812-4818
    • Rottenberg, M.E.1    Gigliotti Rothfuchs, A.2    Gigliotti, D.3
  • 20
    • 0346734115 scopus 로고    scopus 로고
    • Transcriptome analysis of chlamydial growth during IFN-gamma-mediated persistence and reactivation
    • Belland RJ, Nelson DE, Virok D, et al. Transcriptome analysis of chlamydial growth during IFN-gamma-mediated persistence and reactivation. Proc Natl Acad Sci U S A 2003; 100: 15971-15976.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 15971-15976
    • Belland, R.J.1    Nelson, D.E.2    Virok, D.3
  • 21
    • 0036259796 scopus 로고    scopus 로고
    • Proteomic analysis of differentially expressed Chlamydia pneumoniae genes during persistent infection of HEp-2 cells
    • Molestina RE, Klein JB, Miller RD, Pierce WH, Ramirez JA, Summersgill JT. Proteomic analysis of differentially expressed Chlamydia pneumoniae genes during persistent infection of HEp-2 cells. Infect Immun 2002; 70: 2976-2981.
    • (2002) Infect Immun , vol.70 , pp. 2976-2981
    • Molestina, R.E.1    Klein, J.B.2    Miller, R.D.3    Pierce, W.H.4    Ramirez, J.A.5    Summersgill, J.T.6
  • 22
    • 0034916866 scopus 로고    scopus 로고
    • Regulation by IFN-beta of inducible nitric oxide synthase and interleukin-12/p40 in murine macrophages cultured in the presence of Chlamydia pneumoniae antigens
    • Yao SY, Ljunggren-Rose A, Stratton CW, Mitchell WM, Sriram S. Regulation by IFN-beta of inducible nitric oxide synthase and interleukin-12/p40 in murine macrophages cultured in the presence of Chlamydia pneumoniae antigens. J Interferon Cytokine Res 2001; 21: 137-146.
    • (2001) J Interferon Cytokine Res , vol.21 , pp. 137-146
    • Yao, S.Y.1    Ljunggren-Rose, A.2    Stratton, C.W.3    Mitchell, W.M.4    Sriram, S.5
  • 23
    • 0034715859 scopus 로고    scopus 로고
    • Inhibition of the constitutive and induced IFN-beta production by IL-4 and IL-10 in murine peritoneal macrophages
    • Varano B, Fantuzzi L, Puddu P, Borghi P, Belardelli F, Gessani S. Inhibition of the constitutive and induced IFN-beta production by IL-4 and IL-10 in murine peritoneal macrophages. Virology 2000; 277: 270-277.
    • (2000) Virology , vol.277 , pp. 270-277
    • Varano, B.1    Fantuzzi, L.2    Puddu, P.3    Borghi, P.4    Belardelli, F.5    Gessani, S.6
  • 24
    • 0034881918 scopus 로고    scopus 로고
    • New insights into the role of cytokines in asthma
    • Renauld JC. New insights into the role of cytokines in asthma. J Clin Pathol 2001; 54: 577-589.
    • (2001) J Clin Pathol , vol.54 , pp. 577-589
    • Renauld, J.C.1
  • 25
    • 0031226738 scopus 로고    scopus 로고
    • Allergen-induced cytokine production in atopic disease and its relationship to disease severity
    • Leonard C, Tormey V, Burke C, Poulter LW. Allergen-induced cytokine production in atopic disease and its relationship to disease severity. Am J Respir Cell Mol Biol 1997; 17: 368-375.
    • (1997) Am J Respir Cell Mol Biol , vol.17 , pp. 368-375
    • Leonard, C.1    Tormey, V.2    Burke, C.3    Poulter, L.W.4
  • 26
    • 0036739989 scopus 로고    scopus 로고
    • Polyclonal and allergen-induced cytokine responses in adults with asthma: Resolution of asthma is associated with normalization of IFNgamma responses
    • Smart JM, Horak E, Kemp AS, Robertson CF, Tang ML. Polyclonal and allergen-induced cytokine responses in adults with asthma: resolution of asthma is associated with normalization of IFNgamma responses. J Allergy Clin Immunol 2002; 110: 450-456.
    • (2002) J Allergy Clin Immunol , vol.110 , pp. 450-456
    • Smart, J.M.1    Horak, E.2    Kemp, A.S.3    Robertson, C.F.4    Tang, M.L.5
  • 28
    • 17144403499 scopus 로고    scopus 로고
    • Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus
    • Wark PA, Johnston SL, Bucchieri F, et al. Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus. J Exp Med 2005; 201: 937-947.
    • (2005) J Exp Med , vol.201 , pp. 937-947
    • Wark, P.A.1    Johnston, S.L.2    Bucchieri, F.3
  • 29
    • 0029052324 scopus 로고
    • Negative transcriptional regulation of the interferon-gamma promoter by glucocorticoids and dominant negative mutants of c-Jun
    • Cippitelli M, Sica A, Viggiano V, et al. Negative transcriptional regulation of the interferon-gamma promoter by glucocorticoids and dominant negative mutants of c-Jun. J Biol Chem 1995; 270: 12548-12556.
    • (1995) J Biol Chem , vol.270 , pp. 12548-12556
    • Cippitelli, M.1    Sica, A.2    Viggiano, V.3
  • 30
    • 33644772191 scopus 로고    scopus 로고
    • Variation in the type I interferon gene cluster on 9p21 influences susceptibility to asthma and atopy
    • Chan A, Newman DL, Shon AM, Schneider DH, Kuldanek S, Ober C. Variation in the type I interferon gene cluster on 9p21 influences susceptibility to asthma and atopy. Genes Immun 2006; 7: 169-178.
    • (2006) Genes Immun , vol.7 , pp. 169-178
    • Chan, A.1    Newman, D.L.2    Shon, A.M.3    Schneider, D.H.4    Kuldanek, S.5    Ober, C.6
  • 31
    • 13444283466 scopus 로고    scopus 로고
    • Roles of interferon-regulatory factors in Thelper-cell differentiation
    • Lohoff M, Mak TW. Roles of interferon-regulatory factors in Thelper-cell differentiation. Nat Rev Immunol 2005; 5: 125-135.
    • (2005) Nat Rev Immunol , vol.5 , pp. 125-135
    • Lohoff, M.1    Mak, T.W.2
  • 32
    • 0033891418 scopus 로고    scopus 로고
    • IFNgamma and IL-4 differently regulate inducible NO synthase gene expression through IRF-1 modulation
    • Coccia EM, Stellacci E, Marziali G, Weiss G, Battistini A. IFNgamma and IL-4 differently regulate inducible NO synthase gene expression through IRF-1 modulation. Int Immunol 2000; 12: 977-985.
    • (2000) Int Immunol , vol.12 , pp. 977-985
    • Coccia, E.M.1    Stellacci, E.2    Marziali, G.3    Weiss, G.4    Battistini, A.5
  • 33
    • 0035090628 scopus 로고    scopus 로고
    • Association of IFN-gamma and IFN regulatory factor 1 polymorphisms with childhood atopic asthma
    • Nakao F, Ihara K, Kusuhara K, et al. Association of IFN-gamma and IFN regulatory factor 1 polymorphisms with childhood atopic asthma. J Allergy Clin Immunol 2001; 107: 499-504.
    • (2001) J Allergy Clin Immunol , vol.107 , pp. 499-504
    • Nakao, F.1    Ihara, K.2    Kusuhara, K.3
  • 34
    • 44849088072 scopus 로고    scopus 로고
    • A single nucleotide polymorphism (A -> G) in intron 3 of IFNgamma gene is associated with asthma
    • Kumar A, Ghosh B. A single nucleotide polymorphism (A -> G) in intron 3 of IFNgamma gene is associated with asthma. Genes Immun 2008; 9: 294-301.
    • (2008) Genes Immun , vol.9 , pp. 294-301
    • Kumar, A.1    Ghosh, B.2
  • 35
    • 44849105646 scopus 로고    scopus 로고
    • SOCS-1 protects against Chlamydia pneumoniae-induced lethal inflammation but hampers effective bacterial clearance
    • Yang T, Stark P, Janik K, Wigzell H, Rottenberg ME. SOCS-1 protects against Chlamydia pneumoniae-induced lethal inflammation but hampers effective bacterial clearance. J Immunol 2008; 180: 4040-4049.
    • (2008) J Immunol , vol.180 , pp. 4040-4049
    • Yang, T.1    Stark, P.2    Janik, K.3    Wigzell, H.4    Rottenberg, M.E.5
  • 36
    • 34247265510 scopus 로고    scopus 로고
    • Functional polymorphism in the suppressor of cytokine signaling 1 gene associated with adult asthma
    • Harada M, Nakashima K, Hirota T, et al. Functional polymorphism in the suppressor of cytokine signaling 1 gene associated with adult asthma. Am J Respir Cell Mol Biol 2007; 36: 491-496.
    • (2007) Am J Respir Cell Mol Biol , vol.36 , pp. 491-496
    • Harada, M.1    Nakashima, K.2    Hirota, T.3
  • 37
    • 0028092958 scopus 로고
    • Nitric oxide synthases: Roles, tolls, and controls
    • Nathan C, Xie QW. Nitric oxide synthases: Roles, tolls, and controls. Cell 1994; 78: 915-918.
    • (1994) Cell , vol.78 , pp. 915-918
    • Nathan, C.1    Xie, Q.W.2
  • 38
    • 0038801326 scopus 로고    scopus 로고
    • Acute Chlamydia pneumoniae infection causes coronary endothelial dysfunction in pigs
    • Liuba P, Pesonen E, Paakkari I, et al. Acute Chlamydia pneumoniae infection causes coronary endothelial dysfunction in pigs. Atherosclerosis 2003; 167: 215-222.
    • (2003) Atherosclerosis , vol.167 , pp. 215-222
    • Liuba, P.1    Pesonen, E.2    Paakkari, I.3
  • 39
    • 33845465495 scopus 로고    scopus 로고
    • Analysis of the inducible nitric oxide synthase gene polymorphisms in Czech patients with atopic diseases
    • Holla LI, Stejskalova A, Znojil V, Vasku A. Analysis of the inducible nitric oxide synthase gene polymorphisms in Czech patients with atopic diseases. Clin Exp Allergy 2006; 36: 1592-1601.
    • (2006) Clin Exp Allergy , vol.36 , pp. 1592-1601
    • Holla, L.I.1    Stejskalova, A.2    Znojil, V.3    Vasku, A.4
  • 40
    • 0034861113 scopus 로고    scopus 로고
    • Chlamydia pneumoniae expresses genes required for DNA replication but not cytokinesis during persistent infection of HEp-2 cells
    • Byrne GI, Ouellette SP, Wang Z, et al. Chlamydia pneumoniae expresses genes required for DNA replication but not cytokinesis during persistent infection of HEp-2 cells. Infect Immun 2001; 69: 5423-5429.
    • (2001) Infect Immun , vol.69 , pp. 5423-5429
    • Byrne, G.I.1    Ouellette, S.P.2    Wang, Z.3
  • 41
    • 23844502982 scopus 로고    scopus 로고
    • MyD88 is pivotal for the early inflammatory response and subsequent bacterial clearance and survival in a mouse model of Chlamydia pneumoniae pneumonia
    • Naiki Y, Michelsen KS, Schroder NW, et al. MyD88 is pivotal for the early inflammatory response and subsequent bacterial clearance and survival in a mouse model of Chlamydia pneumoniae pneumonia. J Biol Chem 2005; 280: 29242-29249.
    • (2005) J Biol Chem , vol.280 , pp. 29242-29249
    • Naiki, Y.1    Michelsen, K.S.2    Schroder, N.W.3
  • 42
    • 3142749068 scopus 로고    scopus 로고
    • Chlamydia pneumoniae stimulates IFN-gamma synthesis through MyD88-dependent, TLR2- and TLR4-independent induction of IL-18 release
    • Netea MG, Kullberg BJ, Jacobs LE, et al. Chlamydia pneumoniae stimulates IFN-gamma synthesis through MyD88-dependent, TLR2- and TLR4-independent induction of IL-18 release. J Immunol 2004; 173: 1477-1482.
    • (2004) J Immunol , vol.173 , pp. 1477-1482
    • Netea, M.G.1    Kullberg, B.J.2    Jacobs, L.E.3
  • 44
    • 0033136326 scopus 로고    scopus 로고
    • IL-18 is a potent coinducer of IL-13 in NK and T cells: A new potential role for IL-18 in modulating the immune response
    • Hoshino T, Wiltrout RH, Young HA. IL-18 is a potent coinducer of IL-13 in NK and T cells: A new potential role for IL-18 in modulating the immune response. J Immunol 1999; 162: 5070-5077.
    • (1999) J Immunol , vol.162 , pp. 5070-5077
    • Hoshino, T.1    Wiltrout, R.H.2    Young, H.A.3
  • 45
    • 0033598818 scopus 로고    scopus 로고
    • IL-18, although antiallergic when administered with IL-12, stimulates IL-4 and histamine release by basophils
    • Yoshimoto T, Tsutsui H, Tominaga K, et al. IL-18, although antiallergic when administered with IL-12, stimulates IL-4 and histamine release by basophils. Proc Natl Acad Sci U S A 1999; 96: 13962-13966.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 13962-13966
    • Yoshimoto, T.1    Tsutsui, H.2    Tominaga, K.3
  • 46
    • 5844310778 scopus 로고    scopus 로고
    • IL-18 induction of IgE: Dependence on CD4+ T cells, IL-4 and STAT6
    • Yoshimoto T, Mizutani H, Tsutsui H, et al. IL-18 induction of IgE: Dependence on CD4+ T cells, IL-4 and STAT6. Nat Immunol 2000; 1: 132-137.
    • (2000) Nat Immunol , vol.1 , pp. 132-137
    • Yoshimoto, T.1    Mizutani, H.2    Tsutsui, H.3
  • 47
    • 2542483648 scopus 로고    scopus 로고
    • Association of the interleukin-1 receptor antagonist gene with asthma
    • Gohlke H, Illig T, Bahnweg M, et al. Association of the interleukin-1 receptor antagonist gene with asthma. Am J Respir Crit Care Med 2004; 169: 1217-1223.
    • (2004) Am J Respir Crit Care Med , vol.169 , pp. 1217-1223
    • Gohlke, H.1    Illig, T.2    Bahnweg, M.3
  • 48
    • 33644956924 scopus 로고    scopus 로고
    • The common G-allele of interleukin-18 single-nucleotide polymorphism is a genetic risk factor for atopic asthma. The SAPALDIA Cohort Study
    • Imboden M, Nicod L, Nieters A, et al. The common G-allele of interleukin-18 single-nucleotide polymorphism is a genetic risk factor for atopic asthma. The SAPALDIA Cohort Study. Clin Exp Allergy 2006; 36: 211-218.
    • (2006) Clin Exp Allergy , vol.36 , pp. 211-218
    • Imboden, M.1    Nicod, L.2    Nieters, A.3
  • 49
    • 0041402687 scopus 로고    scopus 로고
    • Association between interleukin-18 gene polymorphism 105A/C and asthma
    • Higa S, Hirano T, Mayumi M, et al. Association between interleukin-18 gene polymorphism 105A/C and asthma. Clin Exp Allergy 2003; 33: 1097-1102.
    • (2003) Clin Exp Allergy , vol.33 , pp. 1097-1102
    • Higa, S.1    Hirano, T.2    Mayumi, M.3
  • 50
    • 20444490428 scopus 로고    scopus 로고
    • Association of interleukin 18 (IL18) polymorphisms with specific IgE levels to mite allergens among asthmatic patients
    • Shin HD, Kim LH, Park BL, et al. Association of interleukin 18 (IL18) polymorphisms with specific IgE levels to mite allergens among asthmatic patients. Allergy 2005; 60: 900-906.
    • (2005) Allergy , vol.60 , pp. 900-906
    • Shin, H.D.1    Kim, L.H.2    Park, B.L.3
  • 51
    • 33746426602 scopus 로고    scopus 로고
    • Human heat shock protein 60 stimulates vascular smooth muscle cell proliferation through Toll-like receptors 2 and 4
    • de Graaf R, Kloppenburg G, Kitslaar PJ, Bruggeman CA, Stassen F. Human heat shock protein 60 stimulates vascular smooth muscle cell proliferation through Toll-like receptors 2 and 4. Microbes Infect 2006; 8: 1859-1865.
    • (2006) Microbes Infect , vol.8 , pp. 1859-1865
    • de Graaf, R.1    Kloppenburg, G.2    Kitslaar, P.J.3    Bruggeman, C.A.4    Stassen, F.5
  • 52
    • 0033557202 scopus 로고    scopus 로고
    • Chlamydial and human heat shock protein 60s activate human vascular endothelium, smooth muscle cells, and macrophages
    • Kol A, Bourcier T, Lichtman AH, Libby P. Chlamydial and human heat shock protein 60s activate human vascular endothelium, smooth muscle cells, and macrophages. J Clin Invest 1999; 103: 571-577.
    • (1999) J Clin Invest , vol.103 , pp. 571-577
    • Kol, A.1    Bourcier, T.2    Lichtman, A.H.3    Libby, P.4
  • 53
    • 0033975855 scopus 로고    scopus 로고
    • Cutting edge: Heat shock protein (HSP) 60 activates the innate immune response: CD14 is an essential receptor for HSP60 activation of mononuclear cells
    • Kol A, Lichtman AH, Finberg RW, Libby P, Kurt-Jones EA. Cutting edge: Heat shock protein (HSP) 60 activates the innate immune response: CD14 is an essential receptor for HSP60 activation of mononuclear cells. J Immunol 2000; 164: 13-17.
    • (2000) J Immunol , vol.164 , pp. 13-17
    • Kol, A.1    Lichtman, A.H.2    Finberg, R.W.3    Libby, P.4    Kurt-Jones, E.A.5
  • 54
    • 0036467447 scopus 로고    scopus 로고
    • Chlamydial heat shock protein 60 activates macrophages and endothelial cells through Toll-like receptor 4 and MD2 in a MyD88-dependent pathway
    • Bulut Y, Faure E, Thomas L, et al. Chlamydial heat shock protein 60 activates macrophages and endothelial cells through Toll-like receptor 4 and MD2 in a MyD88-dependent pathway. J Immunol 2002; 168: 1435-1440.
    • (2002) J Immunol , vol.168 , pp. 1435-1440
    • Bulut, Y.1    Faure, E.2    Thomas, L.3
  • 55
    • 0034650427 scopus 로고    scopus 로고
    • Cutting edge: Heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex
    • Ohashi K, Burkart V, Flohe S, Kolb H. Cutting edge: Heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex. J Immunol 2000; 164: 558-561.
    • (2000) J Immunol , vol.164 , pp. 558-561
    • Ohashi, K.1    Burkart, V.2    Flohe, S.3    Kolb, H.4
  • 56
    • 0036893595 scopus 로고    scopus 로고
    • Polymorphisms in tolllike receptor 4 are not associated with asthma or atopy-related phenotypes
    • Raby BA, Klimecki WT, Laprise C, et al. Polymorphisms in tolllike receptor 4 are not associated with asthma or atopy-related phenotypes. Am J Respir Crit Care Med 2002; 166: 1449-1456.
    • (2002) Am J Respir Crit Care Med , vol.166 , pp. 1449-1456
    • Raby, B.A.1    Klimecki, W.T.2    Laprise, C.3
  • 57
    • 0043031387 scopus 로고    scopus 로고
    • TLR4 gene variants modify endotoxin effects on asthma
    • Werner M, Topp R, Wimmer K, et al. TLR4 gene variants modify endotoxin effects on asthma. J Allergy Clin Immunol 2003; 112: 323-330.
    • (2003) J Allergy Clin Immunol , vol.112 , pp. 323-330
    • Werner, M.1    Topp, R.2    Wimmer, K.3
  • 58
    • 4444221545 scopus 로고    scopus 로고
    • A TLR4 polymorphism is associated with asthma and reduced lipopolysaccharide-induced interleukin-12(p70) responses in Swedish children
    • Fageras BM, Hmani-Aifa M, Lindstrom A, et al. A TLR4 polymorphism is associated with asthma and reduced lipopolysaccharide-induced interleukin-12(p70) responses in Swedish children. J Allergy Clin Immunol 2004; 114: 561-567.
    • (2004) J Allergy Clin Immunol , vol.114 , pp. 561-567
    • Fageras, B.M.1    Hmani-Aifa, M.2    Lindstrom, A.3
  • 59
    • 27844508633 scopus 로고    scopus 로고
    • The effect of polymorphisms at the CD14 promoter and the TLR4 gene on asthma phenotypes in Turkish children with asthma
    • Sackesen C, Karaaslan C, Keskin O, et al. The effect of polymorphisms at the CD14 promoter and the TLR4 gene on asthma phenotypes in Turkish children with asthma. Allergy 2005; 60: 1485-1492.
    • (2005) Allergy , vol.60 , pp. 1485-1492
    • Sackesen, C.1    Karaaslan, C.2    Keskin, O.3
  • 61
    • 20244364812 scopus 로고    scopus 로고
    • NOD1 variation, immunoglobulin E and asthma
    • Hysi P, Kabesch M, Moffatt MF, et al. NOD1 variation, immunoglobulin E and asthma. Hum Mol Genet 2005; 14: 935-941.
    • (2005) Hum Mol Genet , vol.14 , pp. 935-941
    • Hysi, P.1    Kabesch, M.2    Moffatt, M.F.3
  • 62
    • 21344448610 scopus 로고    scopus 로고
    • Association of NOD1 polymorphisms with atopic eczema and related phenotypes
    • Weidinger S, Klopp N, Rummler L, et al. Association of NOD1 polymorphisms with atopic eczema and related phenotypes. J Allergy Clin Immunol 2005; 116: 177-184.
    • (2005) J Allergy Clin Immunol , vol.116 , pp. 177-184
    • Weidinger, S.1    Klopp, N.2    Rummler, L.3
  • 63
    • 33746846152 scopus 로고    scopus 로고
    • Association between exposure to farming, allergies and genetic variation in CARD4/NOD1
    • Eder W, Klimecki W, Yu L, et al. Association between exposure to farming, allergies and genetic variation in CARD4/NOD1. Allergy 2006; 61: 1117-1124.
    • (2006) Allergy , vol.61 , pp. 1117-1124
    • Eder, W.1    Klimecki, W.2    Yu, L.3
  • 64
    • 0037393553 scopus 로고    scopus 로고
    • Association between polymorphisms in caspase recruitment domain containing protein 15 and allergy in two German populations
    • Kabesch M, Peters W, Carr D, Leupold W, Weiland SK, von Mutius E. Association between polymorphisms in caspase recruitment domain containing protein 15 and allergy in two German populations. J Allergy Clin Immunol 2003; 111: 813-817.
    • (2003) J Allergy Clin Immunol , vol.111 , pp. 813-817
    • Kabesch, M.1    Peters, W.2    Carr, D.3    Leupold, W.4    Weiland, S.K.5    von Mutius, E.6
  • 65
    • 22744450775 scopus 로고    scopus 로고
    • Association of CARD15 polymorphisms with atopy-related traits in a population-based cohort of Caucasian adults
    • Weidinger S, Klopp N, Rummler L, et al. Association of CARD15 polymorphisms with atopy-related traits in a population-based cohort of Caucasian adults. Clin Exp Allergy 2005; 35: 866-872.
    • (2005) Clin Exp Allergy , vol.35 , pp. 866-872
    • Weidinger, S.1    Klopp, N.2    Rummler, L.3
  • 66
    • 0026595043 scopus 로고
    • Chronic Chlamydia pneumoniae infection as a risk factor for coronary heart disease in the Helsinki Heart Study
    • Saikku P, Leinonen M, Tenkanen L, et al. Chronic Chlamydia pneumoniae infection as a risk factor for coronary heart disease in the Helsinki Heart Study. Ann Intern Med 1992; 116: 273-278.
    • (1992) Ann Intern Med , vol.116 , pp. 273-278
    • Saikku, P.1    Leinonen, M.2    Tenkanen, L.3
  • 67
    • 0032521232 scopus 로고    scopus 로고
    • Endovascular presence of viable Chlamydia pneumoniae is a common phenomenon in coronary artery disease
    • Maass M, Bartels C, Engel PM, Mamat U, Sievers HH. Endovascular presence of viable Chlamydia pneumoniae is a common phenomenon in coronary artery disease. J Am Coll Cardiol 1998; 31: 827-832.
    • (1998) J Am Coll Cardiol , vol.31 , pp. 827-832
    • Maass, M.1    Bartels, C.2    Engel, P.M.3    Mamat, U.4    Sievers, H.H.5
  • 68
    • 0032750520 scopus 로고    scopus 로고
    • de novo Induction of atherosclerosis by Chlamydia pneumoniae in a rabbit model
    • Fong IW, Chiu B, Viira E, Jang D, Mahony JB. de novo Induction of atherosclerosis by Chlamydia pneumoniae in a rabbit model. Infect Immun 1999; 67: 6048-6055.
    • (1999) Infect Immun , vol.67 , pp. 6048-6055
    • Fong, I.W.1    Chiu, B.2    Viira, E.3    Jang, D.4    Mahony, J.B.5
  • 69
    • 31944440761 scopus 로고    scopus 로고
    • Corticosteroid effects on cell signalling
    • Barnes PJ. Corticosteroid effects on cell signalling. Eur Respir J 2006; 27: 413-426.
    • (2006) Eur Respir J , vol.27 , pp. 413-426
    • Barnes, P.J.1
  • 70
    • 33644784601 scopus 로고    scopus 로고
    • Understanding the pathophysiology of severe asthma to generate new therapeutic opportunities
    • Holgate ST, Holloway J, Wilson S, et al. Understanding the pathophysiology of severe asthma to generate new therapeutic opportunities. J Allergy Clin Immunol 2006; 117: 496-506.
    • (2006) J Allergy Clin Immunol , vol.117 , pp. 496-506
    • Holgate, S.T.1    Holloway, J.2    Wilson, S.3
  • 71
    • 33646746153 scopus 로고    scopus 로고
    • TGF-beta: Its role in asthma and therapeutic potential
    • Howell JE, McAnulty RJ. TGF-beta: Its role in asthma and therapeutic potential. Curr Drug Targets 2006; 7: 547-565.
    • (2006) Curr Drug Targets , vol.7 , pp. 547-565
    • Howell, J.E.1    McAnulty, R.J.2
  • 72
    • 47549101008 scopus 로고    scopus 로고
    • Severe asthma exacerbation: Role of acute Chlamydophila pneumoniae and Mycoplasma pneumoniae infection
    • Cosentini R, Tarsia P, Canetta C, et al. Severe asthma exacerbation: role of acute Chlamydophila pneumoniae and Mycoplasma pneumoniae infection. Respir Res 2008; 9: 48.
    • (2008) Respir Res , vol.9 , pp. 48
    • Cosentini, R.1    Tarsia, P.2    Canetta, C.3
  • 74
    • 40949128223 scopus 로고    scopus 로고
    • Use of cethromycin, a new ketolide, for treatment of community-acquired respiratory infections
    • Hammerschlag MR, Sharma R. Use of cethromycin, a new ketolide, for treatment of community-acquired respiratory infections. Expert Opin Investig Drugs 2008; 17: 387-400.
    • (2008) Expert Opin Investig Drugs , vol.17 , pp. 387-400
    • Hammerschlag, M.R.1    Sharma, R.2
  • 75
    • 29744465421 scopus 로고    scopus 로고
    • Chlamydophila pneumoniae and Mycoplasma pneumoniae: A role in asthma pathogenesis?
    • Johnston SL, Martin RJ. Chlamydophila pneumoniae and Mycoplasma pneumoniae: A role in asthma pathogenesis? Am J Respir Crit Care Med 2005; 172: 1078-1089.
    • (2005) Am J Respir Crit Care Med , vol.172 , pp. 1078-1089
    • Johnston, S.L.1    Martin, R.J.2
  • 76
    • 70350248303 scopus 로고    scopus 로고
    • Meinke, A., Nagy, E., Winkler, B.: WO04113374 (2004).
    • Meinke, A., Nagy, E., Winkler, B.: WO04113374 (2004).
  • 77
    • 70350245316 scopus 로고    scopus 로고
    • Grandi, G., Ratti, G.: WO2005084306 (2005).
    • Grandi, G., Ratti, G.: WO2005084306 (2005).
  • 78
  • 81
    • 0035800872 scopus 로고    scopus 로고
    • Inhibition of AP-1 by the glucocorticoid-inducible protein GILZ
    • Mittelstadt PR, Ashwell JD. Inhibition of AP-1 by the glucocorticoid-inducible protein GILZ. J Biol Chem 2001; 276: 29603-29610.
    • (2001) J Biol Chem , vol.276 , pp. 29603-29610
    • Mittelstadt, P.R.1    Ashwell, J.D.2
  • 82
    • 3042749817 scopus 로고    scopus 로고
    • Glucocorticoids and the Th1/Th2 balance
    • Elenkov IJ. Glucocorticoids and the Th1/Th2 balance. Ann N Y Acad Sci 2004; 1024: 138-146.
    • (2004) Ann N Y Acad Sci , vol.1024 , pp. 138-146
    • Elenkov, I.J.1
  • 84
    • 0029879172 scopus 로고    scopus 로고
    • Reactivation of Chlamydia pneumoniae infection in mice by cortisone treatment
    • Laitinen K, Laurila AL, Leinonen M, Saikku P. Reactivation of Chlamydia pneumoniae infection in mice by cortisone treatment. Infect Immun 1996; 64: 1488-1490.
    • (1996) Infect Immun , vol.64 , pp. 1488-1490
    • Laitinen, K.1    Laurila, A.L.2    Leinonen, M.3    Saikku, P.4
  • 85
    • 9644257233 scopus 로고    scopus 로고
    • Glucocorticoids increase in vitro and in vivo activities of antibiotics against Chlamydophila pneumoniae
    • Caronzolo D, Lucini V, Pannacci M, et al. Glucocorticoids increase in vitro and in vivo activities of antibiotics against Chlamydophila pneumoniae. Antimicrob Agents Chemother 2004; 48: 4878-4881.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 4878-4881
    • Caronzolo, D.1    Lucini, V.2    Pannacci, M.3
  • 86
    • 20244374061 scopus 로고
    • Evaluation of the addition of cromolyn sodium to bronchodilator maintenance therapy in the long-term management of asthma
    • Eigen H, Reid JJ, Dahl R, et al. Evaluation of the addition of cromolyn sodium to bronchodilator maintenance therapy in the long-term management of asthma. J Allergy Clin Immunol 1987; 80: 612-621.
    • (1987) J Allergy Clin Immunol , vol.80 , pp. 612-621
    • Eigen, H.1    Reid, J.J.2    Dahl, R.3
  • 87
    • 1642421795 scopus 로고    scopus 로고
    • Effect of disodium cromoglycate on mast cell-mediated immediate-type allergic reactions
    • Shin HY, Kim JS, An NH, Park RK, Kim HM. Effect of disodium cromoglycate on mast cell-mediated immediate-type allergic reactions. Life Sci 2004; 74: 2877-2887.
    • (2004) Life Sci , vol.74 , pp. 2877-2887
    • Shin, H.Y.1    Kim, J.S.2    An, N.H.3    Park, R.K.4    Kim, H.M.5
  • 88
    • 33645545603 scopus 로고    scopus 로고
    • The inhibitory effect of disodium cromoglycate on the growth of Chlamydophila (Chlamydia) pneumoniae in vitro
    • Yamazaki T, Yamaguchi T, Sasaki N, Inoue M, Sato K, Kishimoto T. The inhibitory effect of disodium cromoglycate on the growth of Chlamydophila (Chlamydia) pneumoniae in vitro. Biol Pharm Bull 2006; 29: 799-800.
    • (2006) Biol Pharm Bull , vol.29 , pp. 799-800
    • Yamazaki, T.1    Yamaguchi, T.2    Sasaki, N.3    Inoue, M.4    Sato, K.5    Kishimoto, T.6
  • 89
    • 34249274950 scopus 로고    scopus 로고
    • Platelet activation triggered by Chlamydia pneumoniae is antagonized by 12-lipoxygenase inhibitors but not cyclooxygenase inhibitors
    • Kalvegren H, Andersson J, Grenegard M, Bengtsson T. Platelet activation triggered by Chlamydia pneumoniae is antagonized by 12-lipoxygenase inhibitors but not cyclooxygenase inhibitors. Eur J Pharmacol 2007; 566: 20-27.
    • (2007) Eur J Pharmacol , vol.566 , pp. 20-27
    • Kalvegren, H.1    Andersson, J.2    Grenegard, M.3    Bengtsson, T.4
  • 90
    • 0942298597 scopus 로고    scopus 로고
    • Platelets are necessary for airway wall remodeling in a murine model of chronic allergic inflammation
    • Pitchford SC, Riffo-Vasquez Y, Sousa A, et al. Platelets are necessary for airway wall remodeling in a murine model of chronic allergic inflammation. Blood 2004; 103: 639-647.
    • (2004) Blood , vol.103 , pp. 639-647
    • Pitchford, S.C.1    Riffo-Vasquez, Y.2    Sousa, A.3
  • 91
    • 24144475242 scopus 로고    scopus 로고
    • Effect of simvastatin, an established lipid-lowering drug, on pulmonary Chlamydia pneumoniae infection in mice
    • Erkkila L, Jauhiainen M, Laitinen K, et al. Effect of simvastatin, an established lipid-lowering drug, on pulmonary Chlamydia pneumoniae infection in mice. Antimicrob Agents Chemother 2005; 49: 3959-3962.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 3959-3962
    • Erkkila, L.1    Jauhiainen, M.2    Laitinen, K.3
  • 93
    • 18644373824 scopus 로고    scopus 로고
    • Chlamydia pneumoniae activates IKK/I kappa B-mediated signaling, which is inhibited by 4-HNE and following primary exposure
    • Donath B, Fischer C, Page S, et al. Chlamydia pneumoniae activates IKK/I kappa B-mediated signaling, which is inhibited by 4-HNE and following primary exposure. Atherosclerosis 2002; 165: 79-88.
    • (2002) Atherosclerosis , vol.165 , pp. 79-88
    • Donath, B.1    Fischer, C.2    Page, S.3
  • 94
    • 0037718616 scopus 로고    scopus 로고
    • Aspirin inhibits Chlamydia pneumoniae-induced NF-kappa B activation, cyclooxygenase-2 expression and prostaglandin E2 synthesis and attenuates chlamydial growth
    • Yoneda H, Miura K, Matsushima H, et al. Aspirin inhibits Chlamydia pneumoniae-induced NF-kappa B activation, cyclooxygenase-2 expression and prostaglandin E2 synthesis and attenuates chlamydial growth. J Med Microbiol 2003; 52: 409-415.
    • (2003) J Med Microbiol , vol.52 , pp. 409-415
    • Yoneda, H.1    Miura, K.2    Matsushima, H.3
  • 95
    • 70350224534 scopus 로고    scopus 로고
    • US20080124338
    • Li, E., Lad, S.: US20080124338 (2008).
    • (2008)
    • Li, E.1    Lad, S.2
  • 96
    • 15544368762 scopus 로고    scopus 로고
    • Age alterations in extent and severity of experimental intranasal infection with Chlamydophila pneumoniae in BALB/c mice
    • Little CS, Bowe A, Lin R, et al. Age alterations in extent and severity of experimental intranasal infection with Chlamydophila pneumoniae in BALB/c mice. Infect Immun 2005; 73: 1723-1734.
    • (2005) Infect Immun , vol.73 , pp. 1723-1734
    • Little, C.S.1    Bowe, A.2    Lin, R.3
  • 97
    • 33747195265 scopus 로고    scopus 로고
    • The influence of age and gender on the population-based incidence of community-acquired pneumonia caused by different microbial pathogens
    • Gutierrez F, Masia M, Mirete C, et al. The influence of age and gender on the population-based incidence of community-acquired pneumonia caused by different microbial pathogens. J Infect 2006; 53: 166-174.
    • (2006) J Infect , vol.53 , pp. 166-174
    • Gutierrez, F.1    Masia, M.2    Mirete, C.3
  • 98
    • 40049104892 scopus 로고    scopus 로고
    • Immunology of asthma and chronic obstructive pulmonary disease
    • Barnes PJ. Immunology of asthma and chronic obstructive pulmonary disease. Nat Rev Immunol 2008; 8: 183-192.
    • (2008) Nat Rev Immunol , vol.8 , pp. 183-192
    • Barnes, P.J.1
  • 99
    • 33845987340 scopus 로고    scopus 로고
    • Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program
    • Moore WC, Bleecker ER, Curran-Everett D, et al. Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program. J Allergy Clin Immunol 2007; 119: 405-413.
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 405-413
    • Moore, W.C.1    Bleecker, E.R.2    Curran-Everett, D.3
  • 100
    • 34447318645 scopus 로고    scopus 로고
    • Epithelial cell proliferation contributes to airway remodeling in severe asthma
    • Cohen L, E X, Tarsi J, et al. Epithelial cell proliferation contributes to airway remodeling in severe asthma. Am J Respir Crit Care Med 2007; 176: 138-145.
    • (2007) Am J Respir Crit Care Med , vol.176 , pp. 138-145
    • Cohen, L.E.X.1    Tarsi, J.2
  • 101
    • 0141817941 scopus 로고    scopus 로고
    • Chlamydia pneumoniae activates epithelial cell proliferation via NF-kappaB and the glucocorticoid receptor
    • Gencay MM, Tamm M, Glanville A, Perruchoud AP, Roth M. Chlamydia pneumoniae activates epithelial cell proliferation via NF-kappaB and the glucocorticoid receptor. Infect Immun 2003; 71: 5814-5822.
    • (2003) Infect Immun , vol.71 , pp. 5814-5822
    • Gencay, M.M.1    Tamm, M.2    Glanville, A.3    Perruchoud, A.P.4    Roth, M.5
  • 102
    • 0036199247 scopus 로고    scopus 로고
    • von HL. Role of persistent infection in the control and severity of asthma: Focus on Chlamydia pneumoniae. Eur Respir J 2002; 19: 546-556.
    • von HL. Role of persistent infection in the control and severity of asthma: Focus on Chlamydia pneumoniae. Eur Respir J 2002; 19: 546-556.
  • 103
    • 0034085527 scopus 로고    scopus 로고
    • Chlamydia pneumoniae and other risk factors for atherosclerosis
    • Leinonen M. Chlamydia pneumoniae and other risk factors for atherosclerosis. J Infect Dis 2000; 181 (Suppl 3): S414-416.
    • (2000) J Infect Dis , vol.181 , Issue.SUPPL. 3
    • Leinonen, M.1
  • 104
    • 0031732416 scopus 로고    scopus 로고
    • Chlamydia pneumoniae infection in patients with diffuse panbronchiolitis and COPD
    • Miyashita N, Niki Y, Nakajima M, Kawane H, Matsushima T. Chlamydia pneumoniae infection in patients with diffuse panbronchiolitis and COPD. Chest 1998; 114: 969-971.
    • (1998) Chest , vol.114 , pp. 969-971
    • Miyashita, N.1    Niki, Y.2    Nakajima, M.3    Kawane, H.4    Matsushima, T.5
  • 105
    • 0031957554 scopus 로고    scopus 로고
    • Chlamydia pneumoniae and its role in chronic obstructive pulmonary disease
    • von Hertzen LC. Chlamydia pneumoniae and its role in chronic obstructive pulmonary disease. Ann Med 1998; 30: 27-37.
    • (1998) Ann Med , vol.30 , pp. 27-37
    • von Hertzen, L.C.1
  • 106
  • 107
    • 0030803032 scopus 로고    scopus 로고
    • Elevated Chlamydia pneumoniae antibodies, cardiovascular events, and azithromycin in male survivors of myocardial infarction
    • Gupta S, Leatham EW, Carrington D, Mendall MA, Kaski JC, Camm AJ. Elevated Chlamydia pneumoniae antibodies, cardiovascular events, and azithromycin in male survivors of myocardial infarction. Circulation 1997; 96: 404-407.
    • (1997) Circulation , vol.96 , pp. 404-407
    • Gupta, S.1    Leatham, E.W.2    Carrington, D.3    Mendall, M.A.4    Kaski, J.C.5    Camm, A.J.6
  • 108
    • 0032562148 scopus 로고    scopus 로고
    • Infection with Chlamydia pneumoniae accelerates the development of atherosclerosis and treatment with azithromycin prevents it in a rabbit model
    • Muhlestein JB, Anderson JL, Hammond EH, et al. Infection with Chlamydia pneumoniae accelerates the development of atherosclerosis and treatment with azithromycin prevents it in a rabbit model. Circulation 1998; 97: 633-636.
    • (1998) Circulation , vol.97 , pp. 633-636
    • Muhlestein, J.B.1    Anderson, J.L.2    Hammond, E.H.3
  • 109
    • 0032565427 scopus 로고    scopus 로고
    • Chlamydia pneumoniae in vascular tissues from heart-transplant donors
    • Taylor-Robinson D, Ong G, Thomas BJ, Rose ML, Yacoub MH. Chlamydia pneumoniae in vascular tissues from heart-transplant donors. Lancet 1998; 351: 1255-1256.
    • (1998) Lancet , vol.351 , pp. 1255-1256
    • Taylor-Robinson, D.1    Ong, G.2    Thomas, B.J.3    Rose, M.L.4    Yacoub, M.H.5
  • 110
    • 0141624402 scopus 로고    scopus 로고
    • Production of basic fibroblast growth factor and interleukin 6 by human smooth muscle cells following infection with Chlamydia pneumoniae
    • Rodel J, Woytas M, Groh A, et al. Production of basic fibroblast growth factor and interleukin 6 by human smooth muscle cells following infection with Chlamydia pneumoniae. Infect Immun 2000; 68: 3635-3641.
    • (2000) Infect Immun , vol.68 , pp. 3635-3641
    • Rodel, J.1    Woytas, M.2    Groh, A.3
  • 111
    • 33845915111 scopus 로고    scopus 로고
    • Lung function and ischemic stroke incidence: The Atherosclerosis Risk in Communities study
    • Hozawa A, Billings JL, Shahar E, Ohira T, Rosamond WD, Folsom AR. Lung function and ischemic stroke incidence: The Atherosclerosis Risk in Communities study. Chest 2006; 130: 1642-1649.
    • (2006) Chest , vol.130 , pp. 1642-1649
    • Hozawa, A.1    Billings, J.L.2    Shahar, E.3    Ohira, T.4    Rosamond, W.D.5    Folsom, A.R.6
  • 112
    • 56249083570 scopus 로고    scopus 로고
    • Prevalence and outcomes of diabetes, hypertension, and cardiovascular disease in chronic obstructive pulmonary disease
    • in press
    • Mannino DM, Thorn D, Swensen A, Holguin F. Prevalence and outcomes of diabetes, hypertension, and cardiovascular disease in chronic obstructive pulmonary disease. Eur Respir J 2008 (in press).
    • (2008) Eur Respir J
    • Mannino, D.M.1    Thorn, D.2    Swensen, A.3    Holguin, F.4
  • 113
    • 10944264671 scopus 로고    scopus 로고
    • Chronic Chlamydia pneumoniae infection is a risk factor for the development of COPD
    • Branden E, Koyi H, Gnarpe J, Gnarpe H, Tornling G. Chronic Chlamydia pneumoniae infection is a risk factor for the development of COPD. Respir Med 2005; 99: 20-26.
    • (2005) Respir Med , vol.99 , pp. 20-26
    • Branden, E.1    Koyi, H.2    Gnarpe, J.3    Gnarpe, H.4    Tornling, G.5
  • 114
    • 34247393246 scopus 로고    scopus 로고
    • Disparate innate immune responses to persistent and acute Chlamydia pneumoniae infection in chronic obstructive pulmonary disease
    • Droemann D, Rupp J, Goldmann T, et al. Disparate innate immune responses to persistent and acute Chlamydia pneumoniae infection in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2007; 175: 791-797.
    • (2007) Am J Respir Crit Care Med , vol.175 , pp. 791-797
    • Droemann, D.1    Rupp, J.2    Goldmann, T.3


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