Novel point mutations in sulfadoxine resistance genes of Plasmodium falciparum from India

Acta Tropica

Volumn 110, Issue 1, 2009, Pages 75-79

  Garg, Shilpi ^a   Saxena, Vishal ^a   Kanchan, Swarna ^a   Sharma, Pooja ^a   Mahajan, Siddharth ^a   Kochar, Dhanpat ^b   Das, Ashis ^a  

^a BIRLA INSTITUTE OF TECHNOLOGY AND SCIENCE   (India)

^b S P MEDICAL COLLEGE   (India)

Author keywords

Dihydrofolate reductase (DHFR); Dihydropteroate synthase (DHPS); Plasmodium falciparum; Pyrimethamine; Sulfadoxine

Indexed keywords

DIHYDROFOLATE REDUCTASE; DIHYDROPTEROATE SYNTHASE; GENOMIC DNA; MUTANT PROTEIN; PYRIMETHAMINE; RIBOSOME RNA; SULFADOXINE;

ALLELE; DRUG RESISTANCE; ENZYME ACTIVITY; GENE EXPRESSION; MALARIA; MUTATION;

ARTICLE; BINDING AFFINITY; DRUG PROTEIN BINDING; GENE SEQUENCE; INDIA; MALARIA; MOLECULAR DOCKING; MULTIDRUG RESISTANCE; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE ISOLATION; PLASMODIUM FALCIPARUM; POINT MUTATION; POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY;

AMINO ACID SUBSTITUTION; ANIMALS; ANTIMALARIALS; DIHYDROPTEROATE SYNTHASE; DNA, PROTOZOAN; DRUG RESISTANCE; HUMANS; INDIA; MALARIA, FALCIPARUM; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PLASMODIUM FALCIPARUM; POINT MUTATION; PROTEIN STRUCTURE, TERTIARY; PROTOZOAN PROTEINS; SEQUENCE ANALYSIS, DNA; SULFADOXINE; TETRAHYDROFOLATE DEHYDROGENASE;

PLASMODIUM FALCIPARUM;

EID: 61449175961     PISSN: 0001706X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actatropica.2009.01.009     Document Type: Article

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