-
1
-
-
0033897173
-
A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse
-
Yung WK, Albright RE, Olson J, et al. A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse. Br J Cancer. 2000;83:588-593.
-
(2000)
Br J Cancer
, vol.83
, pp. 588-593
-
-
Yung, W.K.1
Albright, R.E.2
Olson, J.3
-
2
-
-
0032855728
-
Multicenter phase II trial of temozolomide in patients with anaplastic astrocytoma or anaplastic oligoastrocytoma at first relapse
-
Yung WK, Prados MD, Yaya-Tur R, et al. Multicenter phase II trial of temozolomide in patients with anaplastic astrocytoma or anaplastic oligoastrocytoma at first relapse. J Clin Oncol. 1999;17:2762-2771.
-
(1999)
J Clin Oncol
, vol.17
, pp. 2762-2771
-
-
Yung, W.K.1
Prados, M.D.2
Yaya-Tur, R.3
-
3
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
Stupp R, Mason WP, van den Bent MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med. 2005;352:987-996.
-
(2005)
N Engl J Med
, vol.352
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
van den Bent, M.J.3
-
4
-
-
0023605735
-
-
Stevens MFG, Hickman JA, Langdon SP, et al. Antitumor activity and pharmacokinetics in mice of 8-carbamoyl-3-methyl-imidazo[5,1-d]-1,2,3,5- tetrazin-4(3H)-one (CCRG 81045; M & B 39831), a novel drug with potential as an alternative to dacarbazine. Cancer Res. 1987;47:5846-5852.
-
Stevens MFG, Hickman JA, Langdon SP, et al. Antitumor activity and pharmacokinetics in mice of 8-carbamoyl-3-methyl-imidazo[5,1-d]-1,2,3,5- tetrazin-4(3H)-one (CCRG 81045; M & B 39831), a novel drug with potential as an alternative to dacarbazine. Cancer Res. 1987;47:5846-5852.
-
-
-
-
5
-
-
0026513077
-
Phase I trial of temozolomide (CCRG 81045: M&B 39831: NSC 362856)
-
Newlands ES, Blackledge GR, Slack JA, et al. Phase I trial of temozolomide (CCRG 81045: M&B 39831: NSC 362856). Br J Cancer. 1992;65:287-291.
-
(1992)
Br J Cancer
, vol.65
, pp. 287-291
-
-
Newlands, E.S.1
Blackledge, G.R.2
Slack, J.A.3
-
6
-
-
0030993717
-
Temozolomide: A review of its discovery, chemical properties, pre-clinical development and clinical trials
-
Newlands ES, Stevens MFG, Wedge SR, Wheelhouse RT, Brock C. Temozolomide: a review of its discovery, chemical properties, pre-clinical development and clinical trials. Cancer Treat Rev. 1997;23: 35-61.
-
(1997)
Cancer Treat Rev
, vol.23
, pp. 35-61
-
-
Newlands, E.S.1
Stevens, M.F.G.2
Wedge, S.R.3
Wheelhouse, R.T.4
Brock, C.5
-
7
-
-
0032188739
-
Phase I trial of temozolomide using an extended continuous oral schedule
-
Brock CS, Newlands ES, Wedge SR, et al. Phase I trial of temozolomide using an extended continuous oral schedule. Cancer Res. 1998;58:4363-4367.
-
(1998)
Cancer Res
, vol.58
, pp. 4363-4367
-
-
Brock, C.S.1
Newlands, E.S.2
Wedge, S.R.3
-
8
-
-
0032694518
-
Pharmaco-logic disruption of base excision repair sensitizes mismatch repair- deficient and-proficient colon cancer cells to methylating agents
-
Liu L, Taverna P, Whitacre CM, Chatterjee S, Gerson SL. Pharmaco-logic disruption of base excision repair sensitizes mismatch repair- deficient and-proficient colon cancer cells to methylating agents. Clin Cancer Res. 1999;5:2908-2917.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 2908-2917
-
-
Liu, L.1
Taverna, P.2
Whitacre, C.M.3
Chatterjee, S.4
Gerson, S.L.5
-
9
-
-
22244448679
-
The role of base excision repair in the sensitivity and resistance to temozolomide-mediated cell death
-
Trivedi RN, Almeida KH, Fornsaglio JL, Schamus S, Sobol RW. The role of base excision repair in the sensitivity and resistance to temozolomide-mediated cell death. Cancer Res. 2005;65:6394-6400.
-
(2005)
Cancer Res
, vol.65
, pp. 6394-6400
-
-
Trivedi, R.N.1
Almeida, K.H.2
Fornsaglio, J.L.3
Schamus, S.4
Sobol, R.W.5
-
10
-
-
0036287678
-
Pharmacological strategies to increase the anti- tumor activity of methylating agents
-
Tentori L, Graziani G. Pharmacological strategies to increase the anti- tumor activity of methylating agents. Curr Med Chem. 2002;9:1285-1301.
-
(2002)
Curr Med Chem
, vol.9
, pp. 1285-1301
-
-
Tentori, L.1
Graziani, G.2
-
11
-
-
0034027358
-
Unmasking a killer: DNA O(6)-methylguanine and the cytotoxicity of methylating agents
-
Bignami M, O'Driscoll M, Aquilina G, Karran P. Unmasking a killer: DNA O(6)-methylguanine and the cytotoxicity of methylating agents. Mutat Res. 2000;462:71-82.
-
(2000)
Mutat Res
, vol.462
, pp. 71-82
-
-
Bignami, M.1
O'Driscoll, M.2
Aquilina, G.3
Karran, P.4
-
13
-
-
0036499085
-
Promising survival for patients with newly diagnosed glioblastoma multiforme treated with concomitant radiation plus temozolomide followed by adjuvant temozolomide
-
Stupp R, Dietrich P-Y, Ostermann Kraljevic S, et al. Promising survival for patients with newly diagnosed glioblastoma multiforme treated with concomitant radiation plus temozolomide followed by adjuvant temozolomide. J Clin Oncol. 2002;20:1375-1382.
-
(2002)
J Clin Oncol
, vol.20
, pp. 1375-1382
-
-
Stupp, R.1
Dietrich, P.-Y.2
Ostermann Kraljevic, S.3
-
14
-
-
20044372154
-
MGMT gene silencing and benefit from temozolomide in glioblastoma
-
Hegi ME, Diserens A-C, Gorlia T, et al. MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med. 2005;352:997-1003.
-
(2005)
N Engl J Med
, vol.352
, pp. 997-1003
-
-
Hegi, M.E.1
Diserens, A.-C.2
Gorlia, T.3
-
15
-
-
0034626988
-
Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents
-
Esteller M, Garcia-Foncillas J, Andion E, et al. Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. N Engl J Med. 2000;343:1350-1354.
-
(2000)
N Engl J Med
, vol.343
, pp. 1350-1354
-
-
Esteller, M.1
Garcia-Foncillas, J.2
Andion, E.3
-
16
-
-
1142310735
-
6- methylguanine- deoxyribonucleic acid methyltransferase gene and prognosis in patients with high-grade astrocytic tumors treated with surgery, radiotherapy, and 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3- (2-chloroethyl)-3-nitrosourea- based chemotherapy
-
6- methylguanine- deoxyribonucleic acid methyltransferase gene and prognosis in patients with high-grade astrocytic tumors treated with surgery, radiotherapy, and 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3- (2-chloroethyl)-3-nitrosourea- based chemotherapy. Neurosurgery. 2004;54:349-357.
-
(2004)
Neurosurgery
, vol.54
, pp. 349-357
-
-
Kamiryo, T.1
Tada, K.2
Shiraishi, S.3
Shinojima, N.4
Kochi, M.5
Ushio, Y.6
-
18
-
-
0025105041
-
Isolation and structural characterization of a cDNA clone encoding the human DNA repair protein for O6-alkylguanine
-
Tano K, Shiota S, Collier J, Foote RS, Mitra S. Isolation and structural characterization of a cDNA clone encoding the human DNA repair protein for O6-alkylguanine. Proc Natl Acad Sci USA. 1990;87:686-690.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 686-690
-
-
Tano, K.1
Shiota, S.2
Collier, J.3
Foote, R.S.4
Mitra, S.5
-
19
-
-
51649117107
-
Correlation of O6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity
-
Hegi ME, Liu L, Herman JG, et al. Correlation of O6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity. J Clin Oncol. 2008;26(25):4189-4199.
-
(2008)
J Clin Oncol
, vol.26
, Issue.25
, pp. 4189-4199
-
-
Hegi, M.E.1
Liu, L.2
Herman, J.G.3
-
21
-
-
0030874380
-
6-methylguanine DNA methyltransferase (MGMT) CpG island is associated with heterochro- matinization of the MGMT transcription start site and silencing of the gene
-
6-methylguanine DNA methyltransferase (MGMT) CpG island is associated with heterochro- matinization of the MGMT transcription start site and silencing of the gene. Mol Cell Biol. 1997;17:5612-5619.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 5612-5619
-
-
Watts, G.S.1
Pieper, R.O.2
Costello, J.F.3
Peng, Y.-M.4
Dalton, W.S.5
Futscher, B.W.6
-
22
-
-
3042772549
-
Correlation of clinical features and methylation status of MGMT gene promoter in glioblastomas
-
Blanc JL, Wager M, Guilhot J, et al. Correlation of clinical features and methylation status of MGMT gene promoter in glioblastomas. J Neurooncol. 2004;68:275-283.
-
(2004)
J Neurooncol
, vol.68
, pp. 275-283
-
-
Blanc, J.L.1
Wager, M.2
Guilhot, J.3
-
23
-
-
0344125975
-
Promoter hypermethylation of multiple genes in astrocytic gliomas
-
Gonzalez-Gomez P, Bello MJ, Arjona D, et al. Promoter hypermethylation of multiple genes in astrocytic gliomas. Int J Oncol. 2003;22:601-608.
-
(2003)
Int J Oncol
, vol.22
, pp. 601-608
-
-
Gonzalez-Gomez, P.1
Bello, M.J.2
Arjona, D.3
-
24
-
-
0028171276
-
O6-alkylguanine-DNA alkyltrans- ferase activity of human malignant glioma and its clinical implications
-
Hotta T, Saito Y, Fujita H, et al. O6-alkylguanine-DNA alkyltrans- ferase activity of human malignant glioma and its clinical implications. J Neurooncol. 1994;21:135-140.
-
(1994)
J Neurooncol
, vol.21
, pp. 135-140
-
-
Hotta, T.1
Saito, Y.2
Fujita, H.3
-
25
-
-
32944469010
-
Changing paradigmsan update on the multidisciplinary management of malignant glioma
-
Stupp R, Hegi ME, van den Bent MJ, et al. Changing paradigmsan update on the multidisciplinary management of malignant glioma. Oncologist. 2006;11:165-180.
-
(2006)
Oncologist
, vol.11
, pp. 165-180
-
-
Stupp, R.1
Hegi, M.E.2
van den Bent, M.J.3
-
26
-
-
0033561807
-
6-benzylguanine: A clinical trial establishing the biochemical modulatory dose in tumor tissue for alkyltransferase-directed DNA repair
-
6-benzylguanine: a clinical trial establishing the biochemical modulatory dose in tumor tissue for alkyltransferase-directed DNA repair. Cancer Res. 1999;59:2402-2410.
-
(1999)
Cancer Res
, vol.59
, pp. 2402-2410
-
-
Spiro, T.P.1
Gerson, S.L.2
Liu, L.3
-
28
-
-
0028174027
-
Inactivation of O6-alkylguanine-DNA alkyltransferase in human peripheral blood mononuclear cells by temozolomide
-
Lee SM, Thatcher N, Crowther D, Margison GP. Inactivation of O6-alkylguanine-DNA alkyltransferase in human peripheral blood mononuclear cells by temozolomide. Br J Cancer. 1994;69:452-456.
-
(1994)
Br J Cancer
, vol.69
, pp. 452-456
-
-
Lee, S.M.1
Thatcher, N.2
Crowther, D.3
Margison, G.P.4
-
29
-
-
0942266264
-
6-benzylguanine suppression of O6-alkylguanine-DNA alkyltransferase in anaplastic gliomas
-
6-benzylguanine suppression of O6-alkylguanine-DNA alkyltransferase in anaplastic gliomas. Neuro-Oncology. 2004;6:28-32.
-
(2004)
Neuro-Oncology
, vol.6
, pp. 28-32
-
-
Schold Jr, S.C.1
Kokkinakis, D.M.2
Chang, S.M.3
-
30
-
-
34548213721
-
Efficacy and tolerability of temozolomide in an alternating weekly regimen in patients with recurrent glioma
-
Wick A, Felsberg J, Steinbach JP, et al. Efficacy and tolerability of temozolomide in an alternating weekly regimen in patients with recurrent glioma. J Clin Oncol. 2007;25:3357-3361.
-
(2007)
J Clin Oncol
, vol.25
, pp. 3357-3361
-
-
Wick, A.1
Felsberg, J.2
Steinbach, J.P.3
-
31
-
-
0033623440
-
6-methylguanine formation, repair protein depletion and clinical outcome with a 4 hr schedule of temozolomide in the treatment of advanced melanoma: Results of a phase II study
-
6-methylguanine formation, repair protein depletion and clinical outcome with a 4 hr schedule of temozolomide in the treatment of advanced melanoma: results of a phase II study. Int J Cancer. 2000;88:469-473.
-
(2000)
Int J Cancer
, vol.88
, pp. 469-473
-
-
Middleton, M.R.1
Lee, S.M.2
Arance, A.3
Wood, M.4
Thatcher, N.5
Margison, G.P.6
-
32
-
-
1442283179
-
Selective CD4+ lymphopenia in melanoma patients treated with temozolomide: A toxicity with therapeutic implications
-
Su YB, Sohn S, Krown SE, et al. Selective CD4+ lymphopenia in melanoma patients treated with temozolomide: a toxicity with therapeutic implications. J Clin Oncol. 2004;22:610-616.
-
(2004)
J Clin Oncol
, vol.22
, pp. 610-616
-
-
Su, Y.B.1
Sohn, S.2
Krown, S.E.3
-
33
-
-
0037692954
-
6-alkylguanine-DNA alkyltransferase activity with protracted temozolomide schedules
-
6-alkylguanine-DNA alkyltransferase activity with protracted temozolomide schedules. Br J Cancer. 2003;88:1004-1011.
-
(2003)
Br J Cancer
, vol.88
, pp. 1004-1011
-
-
Tolcher, A.W.1
Gerson, S.L.2
Denis, L.3
-
34
-
-
20244372425
-
Randomized phase II study of temozolomide and radiotherapy compared with radiotherapy alone in newly diagnosed glioblastoma multiforme
-
Athanassiou H, Synodinou M, Maragoudakis E, et al. Randomized phase II study of temozolomide and radiotherapy compared with radiotherapy alone in newly diagnosed glioblastoma multiforme. J Clin Oncol. 2005;23:2372-2377.
-
(2005)
J Clin Oncol
, vol.23
, pp. 2372-2377
-
-
Athanassiou, H.1
Synodinou, M.2
Maragoudakis, E.3
-
35
-
-
61449225287
-
Alternative schedules of adjuvant temozolomide in glioblastoma multiforme: A 6-year experience [abstract 1511]
-
60s
-
Buttolo L, Giunta F, Ferrari VD, Grisanti S, Marini G, Mortini P. Alternative schedules of adjuvant temozolomide in glioblastoma multiforme: a 6-year experience [abstract 1511]. J Clin Oncol. 2006;24(suppl):60s.
-
(2006)
J Clin Oncol
, vol.24
, Issue.SUPPL.
-
-
Buttolo, L.1
Giunta, F.2
Ferrari, V.D.3
Grisanti, S.4
Marini, G.5
Mortini, P.6
-
36
-
-
34547130338
-
Temozolomide in glioblas- toma: Results of administration at first relapse and in newly diagnosed cases. Is still proposable an alternative schedule to concomitant protocol?
-
Caroli M, Locatelli M, Campanella R, et al. Temozolomide in glioblas- toma: results of administration at first relapse and in newly diagnosed cases. Is still proposable an alternative schedule to concomitant protocol? J Neurooncol. 2007;84:71-77.
-
(2007)
J Neurooncol
, vol.84
, pp. 71-77
-
-
Caroli, M.1
Locatelli, M.2
Campanella, R.3
-
37
-
-
34248198326
-
Correlation between O6-meth- ylguanine-DNA methyltransferase and survival in inoperable newly diagnosed glioblastoma patients treated with neoadjuvant temozolo- mide
-
Chinot OL, Barrie M, Fuentes S, et al. Correlation between O6-meth- ylguanine-DNA methyltransferase and survival in inoperable newly diagnosed glioblastoma patients treated with neoadjuvant temozolo- mide. J Clin Oncol. 2007;25:1470-1475.
-
(2007)
J Clin Oncol
, vol.25
, pp. 1470-1475
-
-
Chinot, O.L.1
Barrie, M.2
Fuentes, S.3
-
38
-
-
20344407908
-
Temozolomide combined with irradiation as postoperative treatment of primary glioblastoma multiforme. Phase I/II study
-
Combs SE, Gutwein S, Schulz-Ertner D, et al. Temozolomide combined with irradiation as postoperative treatment of primary glioblastoma multiforme. Phase I/II study. Strahlenther Onkol. 2005;181:372-377.
-
(2005)
Strahlenther Onkol
, vol.181
, pp. 372-377
-
-
Combs, S.E.1
Gutwein, S.2
Schulz-Ertner, D.3
-
39
-
-
61449155124
-
Re-irradiation using high precision radiotherapy and concomitant temozolomide in patients with recurrent glioma: Re-challenge with radio-chemotherapy [abstract 12517]
-
606s
-
Combs SE, Schulz-Ertner D, Welzel T, Bischof M, Debus J. Re-irradiation using high precision radiotherapy and concomitant temozolomide in patients with recurrent glioma: re-challenge with radio-chemotherapy [abstract 12517]. J Clin Oncol. 2007;25(suppl):606s.
-
(2007)
J Clin Oncol
, vol.25
, Issue.SUPPL.
-
-
Combs, S.E.1
Schulz-Ertner, D.2
Welzel, T.3
Bischof, M.4
Debus, J.5
-
40
-
-
77949273039
-
An analysis of two different schedules of radiochemotherapy with concomitant temozolomide in high grade gliomas [abstract 2035]
-
83s
-
D'Agostino G, Balducci M, Anile C, et al. An analysis of two different schedules of radiochemotherapy with concomitant temozolomide in high grade gliomas [abstract 2035]. J Clin Oncol. 2007;25(suppl):83s.
-
(2007)
J Clin Oncol
, vol.25
, Issue.SUPPL.
-
-
D'Agostino, G.1
Balducci, M.2
Anile, C.3
-
41
-
-
61449109766
-
Temo- zolomide (TMZ) in radio-chemotherapy combined schedule for treatment of newly-diagnosed high-grade gliomas(HGG) [abstract 1578]
-
133s
-
Montemaggi P, Guerrieri P, Mortellaro G, Piazza D, Rizzo S. Temo- zolomide (TMZ) in radio-chemotherapy combined schedule for treatment of newly-diagnosed high-grade gliomas(HGG) [abstract 1578]. J Clin Oncol. 2005;23(suppl):133s.
-
(2005)
J Clin Oncol
, vol.23
, Issue.SUPPL.
-
-
Montemaggi, P.1
Guerrieri, P.2
Mortellaro, G.3
Piazza, D.4
Rizzo, S.5
-
43
-
-
79953758032
-
A randomized phase II trial of concurrent temozolomide (TMZ) and radiotherapy (RT) followed by dose dense compared to metronomic TMZ and maintenance cisretinoic acid for patients with newly diagnosed glioblastoma multi-forme (GBM) [abstract 2031]
-
82s
-
Sul J, Panageas KS, Lassman AB, et al. A randomized phase II trial of concurrent temozolomide (TMZ) and radiotherapy (RT) followed by dose dense compared to metronomic TMZ and maintenance cisretinoic acid for patients with newly diagnosed glioblastoma multi-forme (GBM) [abstract 2031]. J Clin Oncol. 2007;25(suppl):82s.
-
(2007)
J Clin Oncol
, vol.25
, Issue.SUPPL.
-
-
Sul, J.1
Panageas, K.S.2
Lassman, A.B.3
-
44
-
-
61449192948
-
Therapeutic results in patients with an aplastic astrocytoma (AA) or glioblastoma multiforme (GBM) receiving postoperative radiotherapy and concomitant temozolomide [poster]
-
Presented at: October 30-November 3, Paris, France
-
Zorlu F, Sari S, Ozyigit G, et al. Therapeutic results in patients with an aplastic astrocytoma (AA) or glioblastoma multiforme (GBM) receiving postoperative radiotherapy and concomitant temozolomide [poster]. Presented at: ECCO 13-the European Cancer Conference; October 30-November 3, 2005; Paris, France.
-
(2005)
ECCO 13-the European Cancer Conference
-
-
Zorlu, F.1
Sari, S.2
Ozyigit, G.3
-
45
-
-
61449194914
-
Phase II study of temozolomide (TMZ) administered on a 7 days on-7days off regimen as primary treatment before radiotherapy (RT) in inoperable newly diagnosed glioblastoma multiforme (GBM) [abstract 1523]
-
119s
-
Chinot O, Barrie M, Cournede A, et al. Phase II study of temozolomide (TMZ) administered on a 7 days on-7days off regimen as primary treatment before radiotherapy (RT) in inoperable newly diagnosed glioblastoma multiforme (GBM) [abstract 1523]. J Clin Oncol. 2005; 23(suppl):119s.
-
(2005)
J Clin Oncol
, vol.23
, Issue.SUPPL.
-
-
Chinot, O.1
Barrie, M.2
Cournede, A.3
-
46
-
-
0027294649
-
Recursive partitioning analysis of prognostic factors in three Radiation Therapy Oncology Group malignant glioma trials
-
Curran WJ Jr, Scott CB, Horton J, et al. Recursive partitioning analysis of prognostic factors in three Radiation Therapy Oncology Group malignant glioma trials. J Natl Cancer Inst. 1993;85:704-710.
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 704-710
-
-
Curran Jr, W.J.1
Scott, C.B.2
Horton, J.3
-
47
-
-
21344454458
-
Neoadjuvant phase II multicentre study of new agents in patients with malignant glioma after minimal surgery. Report of a cohort of 187 patients treated with temozolo- mide
-
Brada M, Ashley S, Dowe A, et al. Neoadjuvant phase II multicentre study of new agents in patients with malignant glioma after minimal surgery. Report of a cohort of 187 patients treated with temozolo- mide. Ann Oncol. 2005;16:942-949.
-
(2005)
Ann Oncol
, vol.16
, pp. 942-949
-
-
Brada, M.1
Ashley, S.2
Dowe, A.3
-
48
-
-
0032435612
-
6-alkylguanine-DNA alkyltransferase analysis and response to Temodal in newly diagnosed malignant glioma
-
6-alkylguanine-DNA alkyltransferase analysis and response to Temodal in newly diagnosed malignant glioma. J Clin Oncol. 1998;16:3851-3857.
-
(1998)
J Clin Oncol
, vol.16
, pp. 3851-3857
-
-
Friedman, H.S.1
McLendon, R.E.2
Kerby, T.3
-
49
-
-
0036788961
-
A phase II study of temozolomide in patients with newly diagnosed supratentorial malignant glioma before radiation therapy
-
Gilbert MR, Friedman HS, Kuttesch JF, et al. A phase II study of temozolomide in patients with newly diagnosed supratentorial malignant glioma before radiation therapy. Neuro-Oncology. 2002;4:261-267.
-
(2002)
Neuro-Oncology
, vol.4
, pp. 261-267
-
-
Gilbert, M.R.1
Friedman, H.S.2
Kuttesch, J.F.3
-
50
-
-
61449209566
-
A randomized phase II trial of concurrent temozolomide (TMZ) and radiotherapy (RT) followed by dose-dense compared to metronomic TMZ and maintenance cis- retinoic acid for patients with newly diagnosed glioblastoma multiforme (GBM) [Abstract MA-557]
-
Clarke J, Sul J, DeAngelis L, et al. A randomized phase II trial of concurrent temozolomide (TMZ) and radiotherapy (RT) followed by dose-dense compared to metronomic TMZ and maintenance cis- retinoic acid for patients with newly diagnosed glioblastoma multiforme (GBM) [Abstract MA-557]. Neuro-Oncology. 2007:530.
-
(2007)
Neuro-Oncology
, pp. 530
-
-
Clarke, J.1
Sul, J.2
DeAngelis, L.3
-
51
-
-
40149086956
-
-
51, Available at, Accessed February 5, 2008
-
51.European Organisation for Research and Treatment of Cancer. Brain Tumour Group: Ongoing Trials. Available at http://groups.eortc.be/ brain/html/trials.html. Accessed February 5, 2008.
-
Brain Tumour Group: Ongoing Trials
-
-
-
53
-
-
39749084577
-
Multi-institutional phase II study of temozolomide administered twice daily in the treatment of recurrent high-grade gliomas
-
Balmaceda C, Peereboom D, Pannullo S, et al. Multi-institutional phase II study of temozolomide administered twice daily in the treatment of recurrent high-grade gliomas. Cancer. 2008;112:1139-1146.
-
(2008)
Cancer
, vol.112
, pp. 1139-1146
-
-
Balmaceda, C.1
Peereboom, D.2
Pannullo, S.3
-
54
-
-
61449252260
-
Phase II study of extended schedule temozolomide in refractory gliomas [abstract 1516]
-
62s
-
Berrocal A, Perez-Segura P, Gil M, et al. Phase II study of extended schedule temozolomide in refractory gliomas [abstract 1516]. J Clin Oncol. 2006;24(suppl):62s.
-
(2006)
J Clin Oncol
, vol.24
, Issue.SUPPL.
-
-
Berrocal, A.1
Perez-Segura, P.2
Gil, M.3
-
55
-
-
33750432843
-
Temozolomide 3 weeks on and 1 week off as first-line therapy for recurrent glioblastoma: Phase II study from Gruppo Italiano Cooperativo di Neuro-oncologia (GICNO)
-
Brandes AA, Tosoni A, Cavallo G, et al. Temozolomide 3 weeks on and 1 week off as first-line therapy for recurrent glioblastoma: phase II study from Gruppo Italiano Cooperativo di Neuro-oncologia (GICNO). Br J Cancer. 2006;95:1155-1160.
-
(2006)
Br J Cancer
, vol.95
, pp. 1155-1160
-
-
Brandes, A.A.1
Tosoni, A.2
Cavallo, G.3
-
56
-
-
61449180933
-
2 a day for 21 days every 28: a GICNO (Italian Neuro-Oncology Group) study [abstract 1541]
-
124s
-
2 a day for 21 days every 28: a GICNO (Italian Neuro-Oncology Group) study [abstract 1541]. J Clin Oncol. 2005;23(suppl) 124s.
-
(2005)
J Clin Oncol
, vol.23
, Issue.SUPPL.
-
-
Brandes, A.A.1
Cavallo, G.2
Tosoni, A.3
-
57
-
-
80855145602
-
Protracted administration of low doses of temozolomide (TMZ) in the treatment of relapse glioblastoma (GBM) enhances the antitumor activity of this agent [abstract 1572]
-
75s
-
D'Amico A, Gabbani M, Dall'oglio S, et al. Protracted administration of low doses of temozolomide (TMZ) in the treatment of relapse glioblastoma (GBM) enhances the antitumor activity of this agent [abstract 1572]. J Clin Oncol. 2006;23(suppl):75s.
-
(2006)
J Clin Oncol
, vol.23
, Issue.SUPPL.
-
-
D'Amico, A.1
Gabbani, M.2
Dall'oglio, S.3
-
58
-
-
61449259597
-
Temozolomide in resistant or relapsed neuroblastoma [abstract 8522]
-
805s
-
Donfrancesco A, Milano GM, Jenkner A, et al. Temozolomide in resistant or relapsed neuroblastoma [abstract 8522]. J Clin Oncol. 2005;23(suppl):805s.
-
(2005)
J Clin Oncol
, vol.23
, Issue.SUPPL.
-
-
Donfrancesco, A.1
Milano, G.M.2
Jenkner, A.3
-
59
-
-
84886582159
-
Re-challenge with temozolomide (TMZ) at recurrence in high-grade gliomas (HGG) [abstract 2034]
-
83s
-
Jauch T, Hau P, Bogdahn U. Re-challenge with temozolomide (TMZ) at recurrence in high-grade gliomas (HGG) [abstract 2034]. J Clin Oncol. 2007;25(suppl):83s.
-
(2007)
J Clin Oncol
, vol.25
, Issue.SUPPL.
-
-
Jauch, T.1
Hau, P.2
Bogdahn, U.3
-
60
-
-
0036208462
-
A phase II study of extended low-dose temozolomide in recurrent malignant gliomas
-
Khan RB, Raizer JJ, Malkin MG, Bazylewicz KA, Abrey LE. A phase II study of extended low-dose temozolomide in recurrent malignant gliomas. Neuro-Oncology. 2002;4:39-43.
-
(2002)
Neuro-Oncology
, vol.4
, pp. 39-43
-
-
Khan, R.B.1
Raizer, J.J.2
Malkin, M.G.3
Bazylewicz, K.A.4
Abrey, L.E.5
-
61
-
-
40149093387
-
A multicenter cohort study of dose-dense temozolomide (21 of 28 days) for the treatment of recurrent anaplastic astrocytoma or oligoastrocytoma
-
Neyns B, Chaskis C, Joosens E, et al. A multicenter cohort study of dose-dense temozolomide (21 of 28 days) for the treatment of recurrent anaplastic astrocytoma or oligoastrocytoma. Cancer Invest. 2008;26:269-277.
-
(2008)
Cancer Invest
, vol.26
, pp. 269-277
-
-
Neyns, B.1
Chaskis, C.2
Joosens, E.3
-
62
-
-
61449232335
-
Rechallenge of malignant gliomas with temozolomide-can it be effective? [abstract 2072]
-
93s
-
Strik HM, Buhk JH, Bock HC, Nitsche M, Giese A, Baehr M. Rechallenge of malignant gliomas with temozolomide-can it be effective? [abstract 2072]. J Clin Oncol. 2007;25(suppl): 93s.
-
(2007)
J Clin Oncol
, vol.25
, Issue.SUPPL.
-
-
Strik, H.M.1
Buhk, J.H.2
Bock, H.C.3
Nitsche, M.4
Giese, A.5
Baehr, M.6
-
63
-
-
61449088962
-
A phase II study of prolonged daily temozolomide for low-grade glioma [abstract 1522]
-
119s
-
Wen PY, Schiff D, Doherty L, et al. A phase II study of prolonged daily temozolomide for low-grade glioma [abstract 1522]. J Clin Oncol. 2005;23(suppl):119s.
-
(2005)
J Clin Oncol
, vol.23
, Issue.SUPPL.
-
-
Wen, P.Y.1
Schiff, D.2
Doherty, L.3
-
64
-
-
61449252641
-
The temozolomide RESCUE study: A phase II trial of continuous (28/28) dose-intensive temozolomide (TMZ) after progression on conventional 5/28 day TMZ in patients with recurrent malignant glioma [abstr. 2010]
-
15s
-
Perry JR, Mason WP, Belanger K, et al. The temozolomide RESCUE study: A phase II trial of continuous (28/28) dose-intensive temozolomide (TMZ) after progression on conventional 5/28 day TMZ in patients with recurrent malignant glioma [abstr. 2010]. J. Clin Oncol. 2008;26(suppl):15s.
-
(2008)
J. Clin Oncol
, vol.26
, Issue.SUPPL.
-
-
Perry, J.R.1
Mason, W.P.2
Belanger, K.3
-
65
-
-
2942532908
-
One week on/one week off: A novel active regimen of temozolomide for recurrent glioblastoma
-
Wick W, Steinbach JP, Kuker WM, Dichgans J, Bamberg M, Weller M. One week on/one week off: a novel active regimen of temozolomide for recurrent glioblastoma. Neurology. 2004;62:2113-2115.
-
(2004)
Neurology
, vol.62
, pp. 2113-2115
-
-
Wick, W.1
Steinbach, J.P.2
Kuker, W.M.3
Dichgans, J.4
Bamberg, M.5
Weller, M.6
-
66
-
-
23044508156
-
How lymphotoxic is dose-intensified temozolomide? The glioblastoma experience
-
Wick W, Weller M. How lymphotoxic is dose-intensified temozolomide? The glioblastoma experience. J Clin Oncol. 2005;23:4235-4236.
-
(2005)
J Clin Oncol
, vol.23
, pp. 4235-4236
-
-
Wick, W.1
Weller, M.2
|