Structural evolutions of salicylaldoximes as selective agonists for estrogen receptor β

Journal of Medicinal Chemistry

Volumn 52, Issue 3, 2009, Pages 858-867

  Minutolo, Filippo ^a   Bertini, Simone ^a   Granchi, Carlotta ^a   Marchitiello, Teresa ^a   Prota, Giovanni ^a   Rapposelli, Simona ^a   Tuccinardi, Tiziano ^a   Martinelli, Adriano ^a   Gunther, Jillian R ^b   Carlson, Kathryn E ^b   Katzenellenbogen, John A ^b   Macchia, Marco ^a  

^a UNIVERSITY OF PISA   (Italy)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FLUORINE; PHENYL GROUP; SALICYLALDOXIME; SELECTIVE ESTROGEN RECEPTOR MODULATOR; LIGAND; OXIME;

ARTICLE; BINDING AFFINITY; CHEMICAL MODIFICATION; CONTROLLED STUDY; DRUG SELECTIVITY; DRUG STRUCTURE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HYDROGEN BOND; MOLECULAR MODEL; RECEPTOR AFFINITY; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; DRUG POTENTIATION; ENDOMETRIUM TUMOR; FEMALE; METABOLISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TRANSCRIPTION INITIATION; TUMOR CELL CULTURE;

COMPUTER SIMULATION; ENDOMETRIAL NEOPLASMS; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FEMALE; HUMANS; LIGANDS; MODELS, MOLECULAR; OXIMES; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTIONAL ACTIVATION; TUMOR CELLS, CULTURED;

EID: 61449153994     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm801458t     Document Type: Article

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