Benzopyrans are selective estrogen receptor β agonists with novel activity in models of benign prostatic hyperplasia

Journal of Medicinal Chemistry

Volumn 49, Issue 21, 2006, Pages 6155-6157

  Norman, Bryan H ^a   Dodge, Jeffrey A ^a   Richardson, Timothy I ^a   Borromeo, Peter S ^a   Lugar, Charles W ^a   Jones, Scott A ^a   Chen, Keyue ^a   Wang, Yong ^a   Durst, Gregory L ^a   Barr, Robert J ^a   Montrose Rafizadeh, Chahrzad ^a   Osborne, Harold E ^a   Amos, Robert M ^a   Guo, Sherry ^a   Boodhoo, Amechand ^a   Krishnan, Venkatesh ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZOPYRAN DERIVATIVE; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FINASTERIDE; HORMONE RECEPTOR STIMULATING AGENT; SEX HORMONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG ACTIVITY; DRUG SPECIFICITY; DRUG STRUCTURE; DRUG SYNTHESIS; MALE; MOUSE; NONHUMAN; PROSTATE HYPERTROPHY; X RAY CRYSTALLOGRAPHY;

ANIMALS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; ESTROGENS; FLAVONOIDS; HUMANS; LIGANDS; MALE; MICE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROSTATE; PROSTATIC HYPERPLASIA; SELECTIVE ESTROGEN RECEPTOR MODULATORS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33750105811     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm060491j     Document Type: Article

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