Differential regulation of human and mouse telomerase reverse transcriptase (TERT) promoter activity during testis development

Molecular Reproduction and Development

Volumn 76, Issue 3, 2009, Pages 309-317

  Weise, J M ^a   Gunes C ^a  

^a UNIVERSITY OF HAMBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; STEM CELL FACTOR; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; C57BL 6 MOUSE; CELL PROLIFERATION; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVITY; ENZYME REGULATION; GENE; GENE EXPRESSION; HISTOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; LACZ GENE; MOUSE; NONHUMAN; PERINATAL PERIOD; PREPUBERTY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PUBERTY; REGULATORY MECHANISM; REPORTER GENE; SEMINIFEROUS TUBULE; SPERMATOGONIUM; TERT GENE; TESTIS DEVELOPMENT; TRANSCRIPTION INITIATION; TRANSGENIC MOUSE;

ANIMALS; BETA-GALACTOSIDASE; CELLS, CULTURED; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, REPORTER; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, TRANSGENIC; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS C-KIT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEMINIFEROUS TUBULES; TELOMERASE; TESTIS;

BACTERIA (MICROORGANISMS); MUS MUSCULUS;

EID: 61449146998     PISSN: 1040452X     EISSN: 10982795     Source Type: Journal    
DOI: 10.1002/mrd.20954     Document Type: Article

References (40)

1. Avilion AA, Piatyszek MA, Gupta J, Shay JW, Bacchetti S, Greider CW. 1996. Human telomerase RNA and telomerase activity in immortal cell lines and tumor tissues. Cancer Res 56:645-650.
2. Bellve AR, Cavicchia JC, Millette CF, O'Brien DA, Bhatnagar YM, Dym M. 1977. Spermatogenic cells of the prepuberal mouse. Isolation and morphological characterization. J Cell Biol 74:68-85.
3. Blasco MA, Funk W, Villeponteau B, Greider CW. 1995. Functional characterization and developmental regulation of mouse telomerase RNA. Science 269:1267-1270.
4. Broccoli D, Young JW, de Lange T. 1995. Telomerase activity in normal and malignant hematopoietic cells. Proc Natl Acad Sci USA 92:9082-9086.
5. Counter CM. 1996. The roles of telomeres and telomerase in cell life span. Mutat Res 366:45-63.
6. Counter CM, Gupta J, Harley CB, Leber B, Bacchetti S. 1995. Telomerase activity in normal leukocytes and in hematologic malignancies. Blood 85:2315-2320.
7. de Rooij DG. 2001. Proliferation and differentiation of spermatogo-nial stem cells. Reproduction 121:347-354.
8. Dolci S, Levati L, Pellegrini M, Faraoni I, Graziani G, Di Carlo A, Geremia R. 2002. Stem cell factor activates telomerase in mouse mitotic spermatogonia and in primordial germ cells. J Cell Sci 115(Pt 8):1643-1649.
9. Drost JB, Lee WR. 1995. Biological basis of germline mutation: Comparisons of spontaneous germline mutation rates among drosophila, mouse, and human. Environ Mol Mutagen 25 (Suppl 26):48-64.
10. Dym M, Jia MC, Dirami G, Price JM, Rabin SJ, Mocchetti I, Ravindranath N. 1995. Expression of c-kit receptor and its auto-phosphorylation in immature rat type A spermatogonia. Biol Reprod 52:8-19.
11. Eisenhauer KM, Gerstein RM, Chiu CP, Conti M, Hsueh AJ. 1997. Telomerase activity in female and male rat germ cells undergoing meiosis and in early embryos. Biol Reprod 56:1120-1125.
12. Feng J, Funk WD, Wang SS, Weinrich SL, Avilion AA, Chiu CP, Adams RR, Chang E, Allsopp RC, Yu J, et al. 1995. The RNA component of human telomerase. Science 269:1236-1241.
13. Fujisawa M, Tanaka H, Tatsumi N, Okada H, Arakawa S, Kamidono S. 1998. Telomerase activity in the testis ofinfertile patients with selected causes. Hum Reprod 13:1476-1479.
14. Greenberg RA, Allsopp RC, Chin L, Morin GB, DePinho RA. 1998. Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation. Oncogene 16:1723-1730.
15. Greider CW, Blackburn EH. 1985. Identification of a specific telo-mere terminal transferase activity in Tetrahymena extracts. Cell 43(2 Pt 1):405-413.
16. Günes C, Lichtsteiner S, Vasserot AP, Englert C. 2000. Expression of the hTERT gene is regulated at the level of transcriptional initiation and repressed by Mad1. Cancer Res 60:2116-2121.
17. Hiyama E, Hiyama K, Yokoyama T, Shay JW. 2001. Immunohisto-chemical detection of telomerase (hTERT) protein in human cancer tissues and a subset of cells in normal tissues. Neoplasia 3:17-26.
18. Horikawa I, Chiang YJ, Patterson T, Feigenbaum L, Leem SH, Michishita E, LarionovV, Hodes RJ, Barrett JC. 2005. Differential cis-regulation of human versus mouse TERT gene expression in vivo: Identification of a human-specific repressive element. Proc Natl Acad Sci USA 102:18437-18442.
19. Kim NW, Piatyszek MA, Prowse KR, Harley CB, West MD, Ho PL, Coviello GM, Wright WE, Weinrich SL, Shay JW. 1994. Specific association of human telomerase activity with immortal cells and cancer. Science 266:2011-2015.
20. Kolquist KA, Ellisen LW, Counter CM, Meyerson M, Tan LK, Weinberg RA, Haber DA, Gerald WL. 1998. Expression of TERT in early premalignant lesions and a subset of cells in normal tissues. Nat Genet 19:182-186.
21. Manova K, Nocka K, Besmer P, Bachvarova RF. 1990. Gonadal expression of c-kit encoded at the W locus of the mouse. Development 110:1057-1069.
22. Manova K, Huang EJ, Angeles M, De Leon V, Sanchez S, Prono-vost SM, Besmer P, Bachvarova RF. 1993. The expression pattern of the c-kit ligand in gonads of mice supports a role for the c-kit receptor in oocyte growth and in proliferation of sper-matogonia. Dev Biol 157:85-99.
23. Mauduit C, Hamamah S, Benahmed M. 1999. Stem cell factor/c-kit system in spermatogenesis. Hum Reprod Update 5:535-545.
24. Meyerson M, CounterCM, Eaton EN, Ellisen LW, Steiner P, Caddle SD, Ziaugra L, Beijersbergen RL, Davidoff MJ, Liu Q, Bacchetti S, Haber DA, Weinberg RA. 1997. hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization. Cell 90:785-795.
25. Nakamura TM, Morin GB, Chapman KB, Weinrich SL, Andrews WH, Lingner J, Harley CB, Cech TR. 1997. Telomerase catalytic subunit homologs from fission yeast and human. Science 277:955-959.
26. Prowse KR, Greider CW. 1995. Developmental and tissue-specific regulation of mouse telomerase and telomere length. Proc Natl Acad Sci USA 92:4818-4822.
27. Ravindranath N, Dalal R, Solomon B, Djakiew D, Dym M. 1997. Loss of telomerase activity during male germ cell differentiation. Endocrinology 138:4026-4029.
28. Ritz JM, Kuhle O, Riethdorf S, Sipos B, Deppert W, Englert C, Günes C. 2005. A novel transgenic mouse model reveals humanlike regulation of an 8-kbp human TERT gene promoter fragment in normal and tumor tissues. Cancer Res 65:1187-1196.
29. Seidl K, Holstein AF. 1990. Organ culture of human seminiferous tubules: A useful tool to study the role of nerve growth factor in the testis. Cell Tissue Res 261:539-547.
30. Sette C, Dolci S, Geremia R, Rossi P. 2000. The role of stem cell factor and of alternative c-kit gene products in the establishment, maintenance and function of germ cells. Int J Dev Biol 44:599-608.
31. Sorrentino V, Giorgi M, Geremia R, Besmer P, Rossi P. 1991. Expression of the c-kit proto-oncogene in the murine male germ cells. Oncogene 6:149-151.
32. Tanemura K, Ogura A, Cheong C, Gotoh H, Matsumoto K, Sato E, Hayashi Y, Lee HW, Kondo T. 2005. Dynamic rearrangement of telomeres during spermatogenesis in mice. Dev Biol 281:196-207.
33. Tatton L, Morley GM, Chopra R, Khwaja A. 2003. The Src-selective kinase inhibitor PP1 also inhibits Kit and Bcr-Abl tyrosine kinases. J Biol Chem 278:4847-4853.
34. Timmons PM, Rigby PW, Poirier F. 2002. The murine seminiferous epithelial cycle is pre-figured in the Sertoli cells of the embryonic testis. Development 129:635-647.
35. Vergouwen RP, Huiskamp R, Bas RJ, Roepers-Gajadien HL, Davids JA, de Rooij DG. 1993. Postnatal development of testic-ular cell populations in mice. J Reprod Fertil 99:479-485.
36. Wright WE, Shay JW. 2000. Telomere dynamics in cancer progression and prevention: Fundamental differences in human and mouse telomere biology. Nat Med 6:849-851.
37. Wright WE, Piatyszek MA, Rainey WE, Byrd W, Shay JW. 1996. Telomerase activity in human germline and embryonic tissues and cells. Dev Genet 18:173-179.
38. Wu YL, Dudognon C, Nguyen E, Hillion J, Pendino F, Tarkanyi I, Aradi J, Lanotte M, Tong JH, Chen GQ, Segal-Bendirdjian E. 2006. Immunodetection of human telomerase reverse-transcrip-tase (hTERT) re-appraised: Nucleolin and telomerase cross paths. J Cell Sci 119:(Pt 13)2797-2806.
39. Yamamoto Y, Sofikitis N, Ono K, Kaki T, Isoyama T, Suzuki N, Miyagawa I. 1999. Postmeiotic modifications of spermatogenic cells are accompanied by inhibition of telomerase activity. Urol Res 27:336-345.
40. Yoshida S, Sukeno M, Nakagawa T, Ohbo K, Nagamatsu G, Suda T, Nabeshima Y. 2006. The first round of mouse spermatogene-sis is a distinctive program that lacks the self-renewing sper-matogonia stage. Development 133:1495-1505.