-
1
-
-
33745273602
-
Potent antiproliferative effects of resveratrol on human osteosarcoma SJSA1 cells: Novel cellular mechanisms involving the ERKs/p53 cascade
-
Alkhalaf M. Jaffal S. (2006) Potent antiproliferative effects of resveratrol on human osteosarcoma SJSA1 cells: novel cellular mechanisms involving the ERKs/p53 cascade. Free Radic. Biol. Med. 41, 318 325.
-
(2006)
Free Radic. Biol. Med.
, vol.41
, pp. 318-325
-
-
Alkhalaf, M.1
Jaffal, S.2
-
2
-
-
1642504413
-
Activation of ERK or inhibition of JNK ameliorates H(2)O(2) cytotoxicity in mouse renal proximal tubule cells
-
Arany I., Megyesi J. K., Kaneto H., Tanaka S. Safirstein R. L. (2004) Activation of ERK or inhibition of JNK ameliorates H(2)O(2) cytotoxicity in mouse renal proximal tubule cells. Kidney Int. 65, 1231 1239.
-
(2004)
Kidney Int.
, vol.65
, pp. 1231-1239
-
-
Arany, I.1
Megyesi, J.K.2
Kaneto, H.3
Tanaka, S.4
Safirstein, R.L.5
-
3
-
-
0032921811
-
Hydrogen peroxide activation of multiple mitogen-activated protein kinases in an oligodendrocyte cell line: Role of extracellular signal-regulated kinase in hydrogen peroxide-induced cell death
-
Bhat N. R. Zhang P. (1999) Hydrogen peroxide activation of multiple mitogen-activated protein kinases in an oligodendrocyte cell line: role of extracellular signal-regulated kinase in hydrogen peroxide-induced cell death. J. Neurochem. 72, 112 119.
-
(1999)
J. Neurochem.
, vol.72
, pp. 112-119
-
-
Bhat, N.R.1
Zhang, P.2
-
4
-
-
0035150219
-
Lipid constituents in oligodendroglial cells alter susceptibility to H2O2-induced apoptotic cell death via ERK activation
-
Brand A., Gil S., Seger R. Yavin E. (2001) Lipid constituents in oligodendroglial cells alter susceptibility to H2O2-induced apoptotic cell death via ERK activation. J. Neurochem. 76, 910 918.
-
(2001)
J. Neurochem.
, vol.76
, pp. 910-918
-
-
Brand, A.1
Gil, S.2
Seger, R.3
Yavin, E.4
-
5
-
-
0033985185
-
The lipid peroxidation product 4-hydroxy-2,3-nonenal increases AP-1-binding activity through caspase activation in neurons
-
Camandola S., Poli G. Mattson M. P. (2000) The lipid peroxidation product 4-hydroxy-2,3-nonenal increases AP-1-binding activity through caspase activation in neurons. J. Neurochem. 74, 159 168.
-
(2000)
J. Neurochem.
, vol.74
, pp. 159-168
-
-
Camandola, S.1
Poli, G.2
Mattson, M.P.3
-
6
-
-
0035282334
-
Mammalian MAP kinase signalling cascades
-
Chang L. Karin M. (2001) Mammalian MAP kinase signalling cascades. Nature 410, 37 40.
-
(2001)
Nature
, vol.410
, pp. 37-40
-
-
Chang, L.1
Karin, M.2
-
7
-
-
2942517676
-
Oxidative neuronal injury. the dark side of ERK1/2
-
Chu C. T., Levinthal D. J., Kulich S. M., Chalovich E. M. DeFranco D. B. (2004) Oxidative neuronal injury. The dark side of ERK1/2. Eur. J. Biochem. 271, 2060 2066.
-
(2004)
Eur. J. Biochem.
, vol.271
, pp. 2060-2066
-
-
Chu, C.T.1
Levinthal, D.J.2
Kulich, S.M.3
Chalovich, E.M.4
Defranco, D.B.5
-
9
-
-
0036852609
-
Covalent modification of amino acid nucleophiles by the lipid peroxidation products 4-hydroxy-2-nonenal and 4-oxo-2-nonenal
-
Doorn J. A. Petersen D. R. (2002) Covalent modification of amino acid nucleophiles by the lipid peroxidation products 4-hydroxy-2-nonenal and 4-oxo-2-nonenal. Chem. Res. Toxicol. 15, 1445 1450.
-
(2002)
Chem. Res. Toxicol.
, vol.15
, pp. 1445-1450
-
-
Doorn, J.A.1
Petersen, D.R.2
-
10
-
-
0025814980
-
Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
-
Esterbauer H., Schaur R. J. Zollner H. (1991) Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic. Biol. Med. 11, 81 128.
-
(1991)
Free Radic. Biol. Med.
, vol.11
, pp. 81-128
-
-
Esterbauer, H.1
Schaur, R.J.2
Zollner, H.3
-
12
-
-
14444279192
-
Identification of a novel inhibitor of mitogen-activated protein kinase kinase
-
Favata M. F., Horiuchi K. Y., Manos E. J. et al. (1998) Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J. Biol. Chem. 273, 18623 18632.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 18623-18632
-
-
Favata, M.F.1
Horiuchi, K.Y.2
Manos, E.J.3
-
13
-
-
0026636441
-
Free radicals, antioxidants, and human disease: Where are we now?
-
Halliwell B., Gutteridge J. M. Cross C. E. (1992) Free radicals, antioxidants, and human disease: where are we now? J. Lab. Clin. Med. 119, 598 620.
-
(1992)
J. Lab. Clin. Med.
, vol.119
, pp. 598-620
-
-
Halliwell, B.1
Gutteridge, J.M.2
Cross, C.E.3
-
14
-
-
0033861887
-
Anti-apoptotic effect of quercetin: Intervention in the JNK- and ERK-mediated apoptotic pathways
-
Ishikawa Y. Kitamura M. (2000) Anti-apoptotic effect of quercetin: intervention in the JNK- and ERK-mediated apoptotic pathways. Kidney Int. 58, 1078 1087.
-
(2000)
Kidney Int.
, vol.58
, pp. 1078-1087
-
-
Ishikawa, Y.1
Kitamura, M.2
-
16
-
-
0032484128
-
Phosphorylation of p53 serine 15 increases interaction with CBP
-
Lambert P. F., Kashanchi F., Radonovich M. F., Shiekhattar R. Brady J. N. (1998) Phosphorylation of p53 serine 15 increases interaction with CBP. J. Biol. Chem. 273, 33048 33053.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 33048-33053
-
-
Lambert, P.F.1
Kashanchi, F.2
Radonovich, M.F.3
Shiekhattar, R.4
Brady, J.N.5
-
17
-
-
0033837032
-
Characterization of 4-oxo-2-nonenal as a novel product of lipid peroxidation
-
Lee S. H. Blair I. A. (2000) Characterization of 4-oxo-2-nonenal as a novel product of lipid peroxidation. Chem. Res. Toxicol. 13, 698 702.
-
(2000)
Chem. Res. Toxicol.
, vol.13
, pp. 698-702
-
-
Lee, S.H.1
Blair, I.A.2
-
18
-
-
0035177030
-
Oxidative DNA damage and cardiovascular disease
-
Lee S. H. Blair I. A. (2001) Oxidative DNA damage and cardiovascular disease. Trends Cardiovasc. Med. 11, 148 155.
-
(2001)
Trends Cardiovasc. Med.
, vol.11
, pp. 148-155
-
-
Lee, S.H.1
Blair, I.A.2
-
19
-
-
0035874967
-
Vitamin C-induced decomposition of lipid hydroperoxides to endogenous genotoxins
-
Lee S. H., Oe T. Blair I. A. (2001) Vitamin C-induced decomposition of lipid hydroperoxides to endogenous genotoxins. Science 292, 2083 2086.
-
(2001)
Science
, vol.292
, pp. 2083-2086
-
-
Lee, S.H.1
Oe, T.2
Blair, I.A.3
-
20
-
-
23844448026
-
4-Oxo-2-nonenal is both more neurotoxic and more protein reactive than 4-hydroxy-2-nonenal
-
Lin D., Lee H. G., Liu Q., Perry G., Smith M. A. Sayre L. M. (2005) 4-Oxo-2-nonenal is both more neurotoxic and more protein reactive than 4-hydroxy-2-nonenal. Chem. Res. Toxicol. 18, 1219 1231.
-
(2005)
Chem. Res. Toxicol.
, vol.18
, pp. 1219-1231
-
-
Lin, D.1
Lee, H.G.2
Liu, Q.3
Perry, G.4
Smith, M.A.5
Sayre, L.M.6
-
21
-
-
0013222143
-
Mass spectroscopic characterization of protein modification by 4-hydroxy-2-(E)-nonenal and 4-oxo-2-(E)-nonenal
-
Liu Z., Minkler P. E. Sayre L. M. (2003) Mass spectroscopic characterization of protein modification by 4-hydroxy-2-(E)-nonenal and 4-oxo-2-(E)-nonenal. Chem. Res. Toxicol. 16, 901 911.
-
(2003)
Chem. Res. Toxicol.
, vol.16
, pp. 901-911
-
-
Liu, Z.1
Minkler, P.E.2
Sayre, L.M.3
-
22
-
-
0037373455
-
Endogenous generation of reactive oxidants and electrophiles and their reactions with DNA and protein
-
Marnett L. J., Riggins J. N. West J. D. (2003) Endogenous generation of reactive oxidants and electrophiles and their reactions with DNA and protein. J. Clin. Invest. 111, 583 593.
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 583-593
-
-
Marnett, L.J.1
Riggins, J.N.2
West, J.D.3
-
23
-
-
0028897831
-
Structural definition of early lysine and histidine adduction chemistry of 4-hydroxynonenal
-
Nadkarni D. V. Sayre L. M. (1995) Structural definition of early lysine and histidine adduction chemistry of 4-hydroxynonenal. Chem. Res. Toxicol. 8, 284 291.
-
(1995)
Chem. Res. Toxicol.
, vol.8
, pp. 284-291
-
-
Nadkarni, D.V.1
Sayre, L.M.2
-
24
-
-
0032422051
-
HNE interacts directly with JNK isoforms in human hepatic stellate cells
-
Parola M., Robino G., Marra F. et al. (1998) HNE interacts directly with JNK isoforms in human hepatic stellate cells. J. Clin. Invest. 102, 1942 1950.
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 1942-1950
-
-
Parola, M.1
Robino, G.2
Marra, F.3
-
26
-
-
33748654795
-
Translesion DNA Synthesis across the heptanone - Etheno-2′- deoxycytidine adduct in cells
-
Pollack M., Yang I. Y., Kim H. Y., Blair I. A. Moriya M. (2006) Translesion DNA Synthesis across the heptanone - etheno-2′-deoxycytidine adduct in cells. Chem. Res. Toxicol. 19, 1074 1079.
-
(2006)
Chem. Res. Toxicol.
, vol.19
, pp. 1074-1079
-
-
Pollack, M.1
Yang, I.Y.2
Kim, H.Y.3
Blair, I.A.4
Moriya, M.5
-
27
-
-
24944556468
-
Nitric oxide regulates angiogenesis through a functional switch involving thrombospondin-1
-
Ridnour L. A., Isenberg J. S., Espey M. G., Thomas D. D., Roberts D. D. Wink D. A. (2005) Nitric oxide regulates angiogenesis through a functional switch involving thrombospondin-1. Proc. Natl Acad. Sci. USA 102, 13147 13152.
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 13147-13152
-
-
Ridnour, L.A.1
Isenberg, J.S.2
Espey, M.G.3
Thomas, D.D.4
Roberts, D.D.5
Wink, D.A.6
-
28
-
-
33847091274
-
4-Hydroxy-2-nonenal adduction of extracellular signal-regulated kinase (Erk) and the inhibition of hepatocyte Erk-Est-like protein-1-activating protein-1 signal transduction
-
Sampey B. P., Carbone D. L., Doorn J. A., Drechsel D. A. Petersen D. R. (2007) 4-Hydroxy-2-nonenal adduction of extracellular signal-regulated kinase (Erk) and the inhibition of hepatocyte Erk-Est-like protein-1-activating protein-1 signal transduction. Mol. Pharmacol. 71, 871 883.
-
(2007)
Mol. Pharmacol.
, vol.71
, pp. 871-883
-
-
Sampey, B.P.1
Carbone, D.L.2
Doorn, J.A.3
Drechsel, D.A.4
Petersen, D.R.5
-
29
-
-
0030989545
-
4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease
-
Sayre L. M., Zelasko D. A., Harris P. L., Perry G., Salomon R. G. Smith M. A. (1997) 4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease. J. Neurochem. 68, 2092 2097.
-
(1997)
J. Neurochem.
, vol.68
, pp. 2092-2097
-
-
Sayre, L.M.1
Zelasko, D.A.2
Harris, P.L.3
Perry, G.4
Salomon, R.G.5
Smith, M.A.6
-
30
-
-
0035003439
-
Chemistry and biochemistry of oxidative stress in neurodegenerative disease
-
Sayre L. M., Smith M. A. Perry G. (2001) Chemistry and biochemistry of oxidative stress in neurodegenerative disease. Curr. Med. Chem. 8, 721 738.
-
(2001)
Curr. Med. Chem.
, vol.8
, pp. 721-738
-
-
Sayre, L.M.1
Smith, M.A.2
Perry, G.3
-
31
-
-
33845390864
-
Protein adducts generated from products of lipid oxidation: Focus on HNE and one
-
Sayre L. M., Lin D., Yuan Q., Zhu X. Tang X. (2006) Protein adducts generated from products of lipid oxidation: focus on HNE and one. Drug Metab. Rev. 38, 651 675.
-
(2006)
Drug Metab. Rev.
, vol.38
, pp. 651-675
-
-
Sayre, L.M.1
Lin, D.2
Yuan, Q.3
Zhu, X.4
Tang, X.5
-
32
-
-
33644865942
-
Identification of a lipid peroxidation product as a potential trigger of the p53 pathway
-
Shibata T., Iio K., Kawai Y., Shibata N., Kawaguchi M., Toi S., Kobayashi M., Yamamoto K. Uchida K. (2006) Identification of a lipid peroxidation product as a potential trigger of the p53 pathway. J. Biol. Chem. 281, 1196 1204.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 1196-1204
-
-
Shibata, T.1
Iio, K.2
Kawai, Y.3
Shibata, N.4
Kawaguchi, M.5
Toi, S.6
Kobayashi, M.7
Yamamoto, K.8
Uchida, K.9
-
33
-
-
0030667702
-
DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
-
Shieh S. Y., Ikeda M., Taya Y. Prives C. (1997) DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell 91, 325 334.
-
(1997)
Cell
, vol.91
, pp. 325-334
-
-
Shieh, S.Y.1
Ikeda, M.2
Taya, Y.3
Prives, C.4
-
34
-
-
0031435944
-
DNA damage induces phosphorylation of the amino terminus of p53
-
Siliciano J. D., Canman C. E., Taya Y., Sakaguchi K., Appella E. Kastan M. B. (1997) DNA damage induces phosphorylation of the amino terminus of p53. Genes Dev. 11, 3471 3481.
-
(1997)
Genes Dev.
, vol.11
, pp. 3471-3481
-
-
Siliciano, J.D.1
Canman, C.E.2
Taya, Y.3
Sakaguchi, K.4
Appella, E.5
Kastan, M.B.6
-
35
-
-
0035969890
-
Apoptosis of PC12 cells by 4-hydroxy-2-nonenal is mediated through selective activation of the c-Jun N-terminal protein kinase pathway
-
Song B. J., Soh Y., Bae M., Pie J., Wan J. Jeong K. (2001) Apoptosis of PC12 cells by 4-hydroxy-2-nonenal is mediated through selective activation of the c-Jun N-terminal protein kinase pathway. Chem. Biol. Interact. 130-132, 943 954.
-
(2001)
Chem. Biol. Interact.
, vol.130-132
, pp. 943-954
-
-
Song, B.J.1
Soh, Y.2
Bae, M.3
Pie, J.4
Wan, J.5
Jeong, K.6
-
36
-
-
0034697364
-
Persistent activation of ERK contributes to glutamate-induced oxidative toxicity in a neuronal cell line and primary cortical neuron cultures
-
Stanciu M., Wang Y., Kentor R. et al. (2000) Persistent activation of ERK contributes to glutamate-induced oxidative toxicity in a neuronal cell line and primary cortical neuron cultures. J. Biol. Chem. 275, 12200 12206.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 12200-12206
-
-
Stanciu, M.1
Wang, Y.2
Kentor, R.3
-
37
-
-
0033836580
-
In Alzheimer's disease, heme oxygenase is coincident with Alz50, an epitope of tau induced by 4-hydroxy-2-nonenal modification
-
Takeda A., Smith M. A., Avila J., Nunomura A., Siedlak S. L., Zhu X., Perry G. Sayre L. M. (2000) In Alzheimer's disease, heme oxygenase is coincident with Alz50, an epitope of tau induced by 4-hydroxy-2-nonenal modification. J. Neurochem. 75, 1234 1241.
-
(2000)
J. Neurochem.
, vol.75
, pp. 1234-1241
-
-
Takeda, A.1
Smith, M.A.2
Avila, J.3
Nunomura, A.4
Siedlak, S.L.5
Zhu, X.6
Perry, G.7
Sayre, L.M.8
-
38
-
-
19944433845
-
Beta-site APP cleaving enzyme up-regulation induced by 4-hydroxynonenal is mediated by stress-activated protein kinases pathways
-
Tamagno E., Parola M., Bardini P. et al. (2005) Beta-site APP cleaving enzyme up-regulation induced by 4-hydroxynonenal is mediated by stress-activated protein kinases pathways. J. Neurochem. 92, 628 636.
-
(2005)
J. Neurochem.
, vol.92
, pp. 628-636
-
-
Tamagno, E.1
Parola, M.2
Bardini, P.3
-
39
-
-
0033593225
-
Activation of stress signaling pathways by the end product of lipid peroxidation. 4-hydroxy-2-nonenal is a potential inducer of intracellular peroxide production
-
Uchida K., Shiraishi M., Naito Y., Torii Y., Nakamura Y. Osawa T. (1999) Activation of stress signaling pathways by the end product of lipid peroxidation. 4-hydroxy-2-nonenal is a potential inducer of intracellular peroxide production. J. Biol. Chem. 274, 2234 2242.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 2234-2242
-
-
Uchida, K.1
Shiraishi, M.2
Naito, Y.3
Torii, Y.4
Nakamura, Y.5
Osawa, T.6
-
40
-
-
0033609306
-
Mutations in serines 15 and 20 of human p53 impair its apoptotic activity
-
Unger T., Sionov R. V., Moallem E., Yee C. L., Howley P. M., Oren M. Haupt Y. (1999) Mutations in serines 15 and 20 of human p53 impair its apoptotic activity. Oncogene 18, 3205 3212.
-
(1999)
Oncogene
, vol.18
, pp. 3205-3212
-
-
Unger, T.1
Sionov, R.V.2
Moallem, E.3
Yee, C.L.4
Howley, P.M.5
Oren, M.6
Haupt, Y.7
-
41
-
-
0032527705
-
The cellular response to oxidative stress: Influences of mitogen-activated protein kinase signalling pathways on cell survival
-
Wang X., Martindale J. L., Liu Y. Holbrook N. J. (1998) The cellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survival. Biochem. J. 333, 291 300.
-
(1998)
Biochem. J.
, vol.333
, pp. 291-300
-
-
Wang, X.1
Martindale, J.L.2
Liu, Y.3
Holbrook, N.J.4
-
42
-
-
1942518353
-
Induction of apoptosis in colorectal carcinoma cells treated with 4-hydroxy-2-nonenal and structurally related aldehydic products of lipid peroxidation
-
West J. D., Ji C., Duncan S. T., Amarnath V., Schneider C., Rizzo C. J., Brash A. R. Marnett L. J. (2004) Induction of apoptosis in colorectal carcinoma cells treated with 4-hydroxy-2-nonenal and structurally related aldehydic products of lipid peroxidation. Chem. Res. Toxicol. 17, 453 462.
-
(2004)
Chem. Res. Toxicol.
, vol.17
, pp. 453-462
-
-
West, J.D.1
Ji, C.2
Duncan, S.T.3
Amarnath, V.4
Schneider, C.5
Rizzo, C.J.6
Brash, A.R.7
Marnett, L.J.8
-
43
-
-
0028880006
-
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
-
Xia Z., Dickens M., Raingeaud J., Davis R. J. Greenberg M. E. (1995) Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 270, 1326 1331.
-
(1995)
Science
, vol.270
, pp. 1326-1331
-
-
Xia, Z.1
Dickens, M.2
Raingeaud, J.3
Davis, R.J.4
Greenberg, M.E.5
-
44
-
-
0029917194
-
Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease
-
Yoritaka A., Hattori N., Uchida K., Tanaka M., Stadtman E. R. Mizuno Y. (1996) Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease. Proc. Natl Acad. Sci. USA 93, 2696 2701.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 2696-2701
-
-
Yoritaka, A.1
Hattori, N.2
Uchida, K.3
Tanaka, M.4
Stadtman, E.R.5
Mizuno, Y.6
-
45
-
-
0037397075
-
Model studies on protein side chain modification by 4-oxo-2-nonenal
-
Zhang W. H., Liu J., Xu G., Yuan Q. Sayre L. M. (2003) Model studies on protein side chain modification by 4-oxo-2-nonenal. Chem. Res. Toxicol. 16, 512 523.
-
(2003)
Chem. Res. Toxicol.
, vol.16
, pp. 512-523
-
-
Zhang, W.H.1
Liu, J.2
Xu, G.3
Yuan, Q.4
Sayre, L.M.5
-
46
-
-
33846845199
-
Mass spectrometric evidence for long-lived protein adducts of 4-oxo-2-nonenal
-
Zhu X. Sayre L. M. (2007) Mass spectrometric evidence for long-lived protein adducts of 4-oxo-2-nonenal. Redox Rep. 12, 45 49.
-
(2007)
Redox Rep.
, vol.12
, pp. 45-49
-
-
Zhu, X.1
Sayre, L.M.2
-
47
-
-
33846187694
-
ERK promotes hydrogen peroxide-induced apoptosis through caspase-3 activation and inhibition of Akt in renal epithelial cells
-
Zhuang S., Yan Y., Daubert R. A., Han J. Schnellmann R. G. (2007) ERK promotes hydrogen peroxide-induced apoptosis through caspase-3 activation and inhibition of Akt in renal epithelial cells. Am. J. Physiol. Renal. Physiol. 292, F440 F447.
-
(2007)
Am. J. Physiol. Renal. Physiol.
, vol.292
-
-
Zhuang, S.1
Yan, Y.2
Daubert, R.A.3
Han, J.4
Schnellmann, R.G.5
|