메뉴 건너뛰기




Volumn 7, Issue 2, 2009, Pages 255-265

Anastellin, the angiostatic fibronectin peptide, is a selective inhibitor of lysophospholipid signaling

Author keywords

[No Author keywords available]

Indexed keywords

ANASTELLIN; FIBRONECTIN; GROWTH FACTOR RECEPTOR; LYSOPHOSPHOLIPID; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; RAS PROTEIN; RHO KINASE; SPHINGOSINE 1 PHOSPHATE; UNCLASSIFIED DRUG;

EID: 61349092340     PISSN: 15417786     EISSN: None     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-08-0195     Document Type: Article
Times cited : (30)

References (61)
  • 1
    • 34250702237 scopus 로고    scopus 로고
    • Cell matrix adhesion in vascular development
    • Hynes RO. Cell matrix adhesion in vascular development. J Thromb Haemost 2007;5:32-40.
    • (2007) J Thromb Haemost , vol.5 , pp. 32-40
    • Hynes, R.O.1
  • 2
    • 0031729124 scopus 로고    scopus 로고
    • Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1-phosphate
    • Goetzl EJ, An S. Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1-phosphate. FASEB J 1998;12:1589-98.
    • (1998) FASEB J , vol.12 , pp. 1589-1598
    • Goetzl, E.J.1    An, S.2
  • 3
    • 0032569235 scopus 로고    scopus 로고
    • Lysophosphatidic acid as a potential biomarkerfor ovarian and other gynecologic cancers
    • Xu Y, Shen Z, Wiper DW, et al. Lysophosphatidic acid as a potential biomarkerfor ovarian and other gynecologic cancers. JAMA 1998;280:719-23.
    • (1998) JAMA , vol.280 , pp. 719-723
    • Xu, Y.1    Shen, Z.2    Wiper, D.W.3
  • 5
    • 0033605294 scopus 로고    scopus 로고
    • A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho
    • Fukuhara S, Murga C, Zohar M, Igishi T, Gutkind JS. A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho. J Biol Chem 1999;274:5868-79.
    • (1999) J Biol Chem , vol.274 , pp. 5868-5879
    • Fukuhara, S.1    Murga, C.2    Zohar, M.3    Igishi, T.4    Gutkind, J.S.5
  • 6
    • 0036261720 scopus 로고    scopus 로고
    • Leukemia-associated Rho guanine nucleotide exchange factor promotes Gαq-coupled activation of RhoA
    • Booden MA, Siderovski DP, Der CJ. Leukemia-associated Rho guanine nucleotide exchange factor promotes Gαq-coupled activation of RhoA. Mol Cell Biol 2002;22:733-8.
    • (2002) Mol Cell Biol , vol.22 , pp. 733-738
    • Booden, M.A.1    Siderovski, D.P.2    CJ, D.3
  • 9
    • 0037131366 scopus 로고    scopus 로고
    • Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase
    • Tokumura A, Majima E, Kariya Y, et al. Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase. J Biol Chem 2002;277:39436 -42.
    • (2002) J Biol Chem , vol.277 , pp. 39436-39442
    • Tokumura, A.1    Majima, E.2    Kariya, Y.3
  • 10
    • 33745466418 scopus 로고    scopus 로고
    • Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development
    • van Meeteren LA, Ruurs P, Stortelers C, et al. Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development. Mol Cell Biol 2006;26:5015-22.
    • (2006) Mol Cell Biol , vol.26 , pp. 5015-5022
    • van Meeteren, L.A.1    Ruurs, P.2    Stortelers, C.3
  • 11
    • 33748757239 scopus 로고    scopus 로고
    • Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid
    • Tanaka M, Okudaira S, Kishi Y, et al. Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid. J Biol Chem 2006;281:25822-30.
    • (2006) J Biol Chem , vol.281 , pp. 25822-25830
    • Tanaka, M.1    Okudaira, S.2    Kishi, Y.3
  • 12
    • 0037162066 scopus 로고    scopus 로고
    • Differential effects of sphingosine 1-phosphate and lysophospha- tidic acid on endothelial cells
    • Panetti JS. Differential effects of sphingosine 1-phosphate and lysophospha- tidic acid on endothelial cells. Biochim Biophys Acta 2002;1582:190-6.
    • (2002) Biochim Biophys Acta , vol.1582 , pp. 190-196
    • Panetti, J.S.1
  • 13
    • 33750456153 scopus 로고    scopus 로고
    • Targeting sphingosine-1-phosphate for cancer therapy
    • Sabbadini RA. Targeting sphingosine-1-phosphate for cancer therapy. Br J Cancer 2006;95:1131 -5.
    • (2006) Br J Cancer , vol.95 , pp. 1131-1135
    • Sabbadini, R.A.1
  • 14
    • 3142744111 scopus 로고    scopus 로고
    • The sphingosine-1-phosphate receptors S1P1, S1P2, and S1P3 function coordinately during embryonic angiogenesis
    • Kono M, Mi Y, Liu Y, et al. The sphingosine-1-phosphate receptors S1P1, S1P2, and S1P3 function coordinately during embryonic angiogenesis. J Biol Chem 2004;279:29367-73.
    • (2004) J Biol Chem , vol.279 , pp. 29367-29373
    • Kono, M.1    Mi, Y.2    Liu, Y.3
  • 15
    • 33644830810 scopus 로고    scopus 로고
    • Validation of an anti-sphingosine-1- phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages
    • Visentin B, Vekich JA, Sibbald BJ, et al. Validation of an anti-sphingosine-1- phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages. Cancer Cell 2006;9:225 -38.
    • (2006) Cancer Cell , vol.9 , pp. 225-238
    • Visentin, B.1    Vekich, J.A.2    Sibbald, B.J.3
  • 16
    • 31544447428 scopus 로고    scopus 로고
    • Antagonism of sphingosine-1-phosphate receptors by FTY720 inhibits angiogenesis and tumor vascularization
    • LaMontagne K, Littlewood-Evans A, Schnell C, et al. Antagonism of sphingosine-1-phosphate receptors by FTY720 inhibits angiogenesis and tumor vascularization. Cancer Res 2006;66:221 -31.
    • (2006) Cancer Res , vol.66 , pp. 221-231
    • LaMontagne, K.1    Littlewood-Evans, A.2    Schnell, C.3
  • 17
    • 0029907050 scopus 로고    scopus 로고
    • A polymeric form of fibronectin has antimetastatic effects against multiple tumor types
    • Pasqualini R, Bourdoulous S, Looivunen E, Woods VL, Jr., Ruoslahti E. A polymeric form of fibronectin has antimetastatic effects against multiple tumor types. Nat Med 1996;2:1197-203.
    • (1996) Nat Med , vol.2 , pp. 1197-1203
    • Pasqualini, R.1    Bourdoulous, S.2    Looivunen, E.3    Woods Jr., V.L.4    Ruoslahti, E.5
  • 18
    • 0035895247 scopus 로고    scopus 로고
    • A fibronectin fragment inhibits tumor growth, angiogenesis, and metastasis
    • Yi M, Ruoslahti E. A fibronectin fragment inhibits tumor growth, angiogenesis, and metastasis. Proc Natl Acad Sci U S A 2001;98:620-4.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 620-624
    • Yi, M.1    Ruoslahti, E.2
  • 19
    • 11244261710 scopus 로고    scopus 로고
    • 1 arrest in human microvessel endothelial cells. Cancer Res 2005;65:148-56.
    • 1 arrest in human microvessel endothelial cells. Cancer Res 2005;65:148-56.
  • 20
    • 0030683639 scopus 로고    scopus 로고
    • Signal characteristics of G protein-transactivated EGF receptor
    • Daub H, Wallasch CLA, Herrlich A, Ullrich A. Signal characteristics of G protein-transactivated EGF receptor. EMBO J 1997;16:7032-44.
    • (1997) EMBO J , vol.16 , pp. 7032-7044
    • Daub, H.1    Wallasch, C.L.A.2    Herrlich, A.3    Ullrich, A.4
  • 21
    • 0141925648 scopus 로고    scopus 로고
    • Involvement of phospholipase D2 in lysophosphatidate-induced transactivation ofplatelet-derived growth factor receptor-β in human bronchial epithelial cells
    • Wang L, Cummings R, Zhao Y, et al. Involvement of phospholipase D2 in lysophosphatidate-induced transactivation ofplatelet-derived growth factor receptor-β in human bronchial epithelial cells. J Biol Chem 2003;278:39931 -40.
    • (2003) J Biol Chem , vol.278 , pp. 39931-39940
    • Wang, L.1    Cummings, R.2    Zhao, Y.3
  • 22
    • 0037044854 scopus 로고    scopus 로고
    • Transactivation of vascular endothelial growth factor (VEGF)receptor Flk-1/KDR is involved in sphingosine 1-phosphate-stimulated phosphorylation of Akt and endothelial nitric-oxide synthase (eNOS)
    • Tanimoto T, Jin Z-G, Berk BC. Transactivation of vascular endothelial growth factor (VEGF)receptor Flk-1/KDR is involved in sphingosine 1-phosphate-stimulated phosphorylation of Akt and endothelial nitric-oxide synthase (eNOS). J Biol Chem 2002;277:42997-3001.
    • (2002) J Biol Chem , vol.277 , pp. 42997-43001
    • Tanimoto, T.1    Jin, Z.-G.2    Berk, B.C.3
  • 23
    • 13944280988 scopus 로고    scopus 로고
    • G protein mediated signaling pathways in lysophospholipid induced cell proliferation and survival
    • Radeff-Huang J, Seasholtz TM, Matteo RG, Brown JH. G protein mediated signaling pathways in lysophospholipid induced cell proliferation and survival. J Cell Biochem 2004;92:949-66.
    • (2004) J Cell Biochem , vol.92 , pp. 949-966
    • Radeff-Huang, J.1    Seasholtz, T.M.2    Matteo, R.G.3    Brown, J.H.4
  • 24
    • 0346788900 scopus 로고    scopus 로고
    • Exogenous and intracellularly generated sphingosine 1-phosphate can regulate cellular processes by divergent pathways
    • Spiegel S, Milstien S. Exogenous and intracellularly generated sphingosine 1-phosphate can regulate cellular processes by divergent pathways. Biochem Soc Trans 2003;31:1216-9.
    • (2003) Biochem Soc Trans , vol.31 , pp. 1216-1219
    • Spiegel, S.1    Milstien, S.2
  • 25
    • 0141482075 scopus 로고    scopus 로고
    • Antiangiogenic proteins require plasma fibronectin or vitronectin for in vivo activity
    • Yi M, Sakai T, Fassler R, Ruoslahti E. Antiangiogenic proteins require plasma fibronectin or vitronectin for in vivo activity. Proc Natl Acad Sci U S A 2003;100:11435-8.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 11435-11438
    • Yi, M.1    Sakai, T.2    Fassler, R.3    Ruoslahti, E.4
  • 26
    • 0032487438 scopus 로고    scopus 로고
    • Fibronectin matrix regulates activation of RHO and CDC42 GTPases and cell cycle progression
    • Bourdoulous S, Orend G, MacKenna DA, Pasqualini R, Ruoslahti E. Fibronectin matrix regulates activation of RHO and CDC42 GTPases and cell cycle progression. J Cell Biol 1998;143:267-76.
    • (1998) J Cell Biol , vol.143 , pp. 267-276
    • Bourdoulous, S.1    Orend, G.2    MacKenna, D.A.3    Pasqualini, R.4    Ruoslahti, E.5
  • 27
    • 2342551058 scopus 로고    scopus 로고
    • Cell adhesion and signaling on the fibronectin 1st type III repeat; requisite roles for cell surface proteoglycans and integrins
    • Mercurius K, Morla A. Cell adhesion and signaling on the fibronectin 1st type III repeat; requisite roles for cell surface proteoglycans and integrins. BMC Cell Biol 2001;2:18-30.
    • (2001) BMC Cell Biol , vol.2 , pp. 18-30
    • Mercurius, K.1    Morla, A.2
  • 28
    • 0345328658 scopus 로고    scopus 로고
    • Stimulation of extracellular matrix remodeling by the first type III repeat in fibronectin
    • Klein RM, Zheng M, Ambesi A, van de Water L, McKeown-Longo PJ. Stimulation of extracellular matrix remodeling by the first type III repeat in fibronectin. J Cell Sci 2003;116:4663-74.
    • (2003) J Cell Sci , vol.116 , pp. 4663-4674
    • Klein, R.M.1    Zheng, M.2    Ambesi, A.3    van de Water, L.4    McKeown-Longo, P.J.5
  • 29
    • 34247534260 scopus 로고    scopus 로고
    • Regulation and biological activities of the autotaxin-LPA axis
    • van Meeteren LA, Moolenaar WH. Regulation and biological activities of the autotaxin-LPA axis. Prog Lipid Res 2007;46:145-60.
    • (2007) Prog Lipid Res , vol.46 , pp. 145-160
    • van Meeteren, L.A.1    Moolenaar, W.H.2
  • 30
    • 35848935411 scopus 로고    scopus 로고
    • HDL serves as a S1P signaling platform mediating a multitude of cardiovascular effects
    • Argraves KM, Argraves WS. HDL serves as a S1P signaling platform mediating a multitude of cardiovascular effects. J Lipid Res 2007;48:2325-33.
    • (2007) J Lipid Res , vol.48 , pp. 2325-2333
    • Argraves, K.M.1    Argraves, W.S.2
  • 31
    • 33646117016 scopus 로고    scopus 로고
    • Estrogen transactivates EGFR via the sphingosine 1-phosphate receptor Edg-3: The role of sphingosine kinase-1
    • Sukocheva O, Wadham C, Holmes A, et al. Estrogen transactivates EGFR via the sphingosine 1-phosphate receptor Edg-3: the role of sphingosine kinase-1. J Cell Biol 2006;173:301-10.
    • (2006) J Cell Biol , vol.173 , pp. 301-310
    • Sukocheva, O.1    Wadham, C.2    Holmes, A.3
  • 32
    • 0036828287 scopus 로고    scopus 로고
    • Lysophosphatidic acid-induced squamous cell carcinoma cell proliferation and motility involves epidermal growth factor receptor signal transactivation
    • Gschwin A, Prenzel N, Ullrich A. Lysophosphatidic acid-induced squamous cell carcinoma cell proliferation and motility involves epidermal growth factor receptor signal transactivation. Cancer Res 2002;62:6329 -36.
    • (2002) Cancer Res , vol.62 , pp. 6329-6336
    • Gschwin, A.1    Prenzel, N.2    Ullrich, A.3
  • 33
    • 0043268853 scopus 로고    scopus 로고
    • Lysophos-phatidic acid signals through mitogen-activated protein kinase-extracellular signal regulated kinase in ovarian theca cells expressing the LPA1/edg2- receptor: Involvement of a nonclassical pathway
    • Budnik LT, Brunswig-Spickenheier B, Mukhopadhyay AK. Lysophos-phatidic acid signals through mitogen-activated protein kinase-extracellular signal regulated kinase in ovarian theca cells expressing the LPA1/edg2- receptor: involvement of a nonclassical pathway. Mol Endocrinol 2003;17:1593 -606.
    • (2003) Mol Endocrinol , vol.17 , pp. 1593-1606
    • Budnik, L.T.1    Brunswig-Spickenheier, B.2    Mukhopadhyay, A.K.3
  • 34
    • 3042587903 scopus 로고    scopus 로고
    • Rho modulates hepatic sinusoidal endothelial fenestrae via regulation of the actin cytoskeleton in rat endothelial cells
    • Yokomori H, Yoshimura K, Funakoshi S, et al. Rho modulates hepatic sinusoidal endothelial fenestrae via regulation of the actin cytoskeleton in rat endothelial cells. Lab Invest 2004;84:857 -64.
    • (2004) Lab Invest , vol.84 , pp. 857-864
    • Yokomori, H.1    Yoshimura, K.2    Funakoshi, S.3
  • 35
    • 0042344706 scopus 로고    scopus 로고
    • Rho GTPases and the regulation of endothelial permeability
    • Wojciak-Stothard B, Ridley AJ. Rho GTPases and the regulation of endothelial permeability. Vascul Pharmacol 2002;39:187-99.
    • (2002) Vascul Pharmacol , vol.39 , pp. 187-199
    • Wojciak-Stothard, B.1    Ridley, A.J.2
  • 37
    • 0037117719 scopus 로고    scopus 로고
    • Lysophosphatidic acid and receptor- mediated activation of endothelial nitric-oxide synthase
    • Kou R, Igarashi J, Michel T. Lysophosphatidic acid and receptor- mediated activation of endothelial nitric-oxide synthase. Biochemistry 2002;41:4982-8.
    • (2002) Biochemistry , vol.41 , pp. 4982-4988
    • Kou, R.1    Igarashi, J.2    Michel, T.3
  • 38
    • 0141621070 scopus 로고    scopus 로고
    • Endostatin associates with lipid rafts and induces reorganization of the actin cytoskeleton via down-regulation of RhoA activity
    • Wickstrom SA, Alitalo K, Keski-Oja J. Endostatin associates with lipid rafts and induces reorganization of the actin cytoskeleton via down-regulation of RhoA activity. J Biol Chem 2003;278:37895 -901.
    • (2003) J Biol Chem , vol.278 , pp. 37895-37901
    • Wickstrom, S.A.1    Alitalo, K.2    Keski-Oja, J.3
  • 39
    • 20144379162 scopus 로고    scopus 로고
    • Endogenous inhibitors of angiogenesis
    • Nyberg P, Xie L, Kalluri R. Endogenous inhibitors of angiogenesis. Cancer Res 2005;65:3967 -79.
    • (2005) Cancer Res , vol.65 , pp. 3967-3979
    • Nyberg, P.1    Xie, L.2    Kalluri, R.3
  • 40
    • 0344736695 scopus 로고    scopus 로고
    • Structure and functional significance of mechanically unfolded fibronectin type III1 intermediates
    • Gao M, Craig D, Lequin O, Campbell ID, Vogel V, Schulten K. Structure and functional significance of mechanically unfolded fibronectin type III1 intermediates. Proc Natl Acad Sci U S A 2003;100:14784-9.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 14784-14789
    • Gao, M.1    Craig, D.2    Lequin, O.3    Campbell, I.D.4    Vogel, V.5    Schulten, K.6
  • 41
    • 9144272598 scopus 로고    scopus 로고
    • Migration-stimulating factor: A genetically truncated onco-fetal fibronectin isoform expressed by carcinoma and tumor-associated stromal cells
    • Schor SL, Ellis IR, Jones S, et al. Migration-stimulating factor: a genetically truncated onco-fetal fibronectin isoform expressed by carcinoma and tumor-associated stromal cells. Cancer Res 2003;63:8827-36.
    • (2003) Cancer Res , vol.63 , pp. 8827-8836
    • Schor, S.L.1    Ellis, I.R.2    Jones, S.3
  • 42
    • 0037177894 scopus 로고    scopus 로고
    • The EIIIA segment of fibronectin is a ligand for integrins α9β1 and α4β1 providing a novel mechanism for regulating cell adhesion by alternative splicing
    • Liao Y-F, Gotwals PJ, Koteliansky VE, Sheppard D, van de Water L. The EIIIA segment of fibronectin is a ligand for integrins α9β1 and α4β1 providing a novel mechanism for regulating cell adhesion by alternative splicing. J Biol Chem 2002;277:14467 -74.
    • (2002) J Biol Chem , vol.277 , pp. 14467-14474
    • Liao, Y.-F.1    Gotwals, P.J.2    Koteliansky, V.E.3    Sheppard, D.4    van de Water, L.5
  • 43
    • 0035971217 scopus 로고    scopus 로고
    • The extra domain A of fibronectin activates Toll-like receptor 4
    • Okamura Y, Watari M, Jerud ES, et al. The extra domain A of fibronectin activates Toll-like receptor 4. J Biol Chem 2001;276:10229 -33.
    • (2001) J Biol Chem , vol.276 , pp. 10229-10233
    • Okamura, Y.1    Watari, M.2    Jerud, E.S.3
  • 44
    • 33748636461 scopus 로고    scopus 로고
    • Heparin-mediated conformational changes in fibronectin expose vascular endothelial growth factor binding sites
    • Mitsi M, Hong Z, Costello CE, Nugent MA. Heparin-mediated conformational changes in fibronectin expose vascular endothelial growth factor binding sites. Biochemistry 2006;45:10319-28.
    • (2006) Biochemistry , vol.45 , pp. 10319-10328
    • Mitsi, M.1    Hong, Z.2    Costello, C.E.3    Nugent, M.A.4
  • 45
    • 33749676409 scopus 로고    scopus 로고
    • Heparin-II domain of fibronectin is a vascular endothelial growth factor-binding domain: Enhancement of VEGF biological activity by a singular growth factor/matrix protein synergism
    • Wijelath ES, Rahman S, Namekata M, et al. Heparin-II domain of fibronectin is a vascular endothelial growth factor-binding domain: enhancement of VEGF biological activity by a singular growth factor/matrix protein synergism. Circ Res 2006;99:863-0.
    • (2006) Circ Res , vol.99 , pp. 863-870
    • Wijelath, E.S.1    Rahman, S.2    Namekata, M.3
  • 46
    • 33745221886 scopus 로고    scopus 로고
    • Autotaxin is overexpressed in glioblastoma multiforme and contributes to cell motility of glioblastoma by converting lysophosphatidylcholine to lysophosphatidic acid
    • Kishi Y, Okudaira S, Tanaka M, et al. Autotaxin is overexpressed in glioblastoma multiforme and contributes to cell motility of glioblastoma by converting lysophosphatidylcholine to lysophosphatidic acid. J Biol Chem 2006;281:17492 -500.
    • (2006) J Biol Chem , vol.281 , pp. 17492-17500
    • Kishi, Y.1    Okudaira, S.2    Tanaka, M.3
  • 47
    • 0037031878 scopus 로고    scopus 로고
    • Role for 18:1 lysophosphatidic acid as an autocrine mediator in prostate cancer cells
    • Xie Y, Gibbs TC, Mukhin YV, Neier KE. Role for 18:1 lysophosphatidic acid as an autocrine mediator in prostate cancer cells. J Biol Chem 2002;277:32516-26.
    • (2002) J Biol Chem , vol.277 , pp. 32516-32526
    • Xie, Y.1    Gibbs, T.C.2    Mukhin, Y.V.3    Neier, K.E.4
  • 48
    • 23744484146 scopus 로고    scopus 로고
    • Integrin α6β4 promotes expression of autotaxin/ENPP2 autocrine motility factor in breast carcinoma cells
    • Chen M, O'Connor KL. Integrin α6β4 promotes expression of autotaxin/ENPP2 autocrine motility factor in breast carcinoma cells. Oncogene 2005;24:5125-30.
    • (2005) Oncogene , vol.24 , pp. 5125-5130
    • Chen, M.1    O'Connor, K.L.2
  • 49
    • 33645525087 scopus 로고    scopus 로고
    • Lysophosphatidic acid is constitutively produced by human peritoneal mesothelial cells and enhances adhesion, migration, and invasion of ovarian cancer cells
    • Ren J, Xiao YJ, Singh LS, et al. Lysophosphatidic acid is constitutively produced by human peritoneal mesothelial cells and enhances adhesion, migration, and invasion of ovarian cancer cells. Cancer Res 2006;66:3006 -14.
    • (2006) Cancer Res , vol.66 , pp. 3006-3014
    • Ren, J.1    Xiao, Y.J.2    Singh, L.S.3
  • 50
    • 10744223639 scopus 로고    scopus 로고
    • Lysophosphatidic acid (LPA) in malignant ascites stimulates motility of human pancreatic cancer cells through LPA1
    • Yamada T, Sato K, Komachi M, et al. Lysophosphatidic acid (LPA) in malignant ascites stimulates motility of human pancreatic cancer cells through LPA1. J Biol Chem 2004;279:6595 -605.
    • (2004) J Biol Chem , vol.279 , pp. 6595-6605
    • Yamada, T.1    Sato, K.2    Komachi, M.3
  • 51
    • 0028069348 scopus 로고
    • Superfibronectin is a functionally distinct form of fibronectin
    • Morla A, Zhang Z, Ruoslahti E. Superfibronectin is a functionally distinct form of fibronectin. Nature 1994;367:193 -6.
    • (1994) Nature , vol.367 , pp. 193-196
    • Morla, A.1    Zhang, Z.2    Ruoslahti, E.3
  • 52
    • 13844315323 scopus 로고    scopus 로고
    • Angiostatic peptides use plasma fibronectin to home to angiogenic vasculature
    • Akerman ME, Pilch J, Peters D, Ruoslahti E. Angiostatic peptides use plasma fibronectin to home to angiogenic vasculature. Proc Natl Acad Sci U S A 2005;102:2040-5.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 2040-2045
    • Akerman, M.E.1    Pilch, J.2    Peters, D.3    Ruoslahti, E.4
  • 53
    • 33644518982 scopus 로고    scopus 로고
    • Fibronectin as target for tumor therapy
    • Kaspar M, Zardi L, Neri D. Fibronectin as target for tumor therapy. Int J Cancer 2006;118:1331 -9.
    • (2006) Int J Cancer , vol.118 , pp. 1331-1339
    • Kaspar, M.1    Zardi, L.2    Neri, D.3
  • 54
    • 0023392493 scopus 로고
    • Transformed human cells produce a new fibronectin isoform by preferential alternative splicing of a previously unobserved exon
    • Zardi L, Carnemolla B, Siri A, et al. Transformed human cells produce a new fibronectin isoform by preferential alternative splicing of a previously unobserved exon. EMBO J 1987;6:2337 -42.
    • (1987) EMBO J , vol.6 , pp. 2337-2342
    • Zardi, L.1    Carnemolla, B.2    Siri, A.3
  • 55
    • 0023131046 scopus 로고
    • Monocloncal antibodies in the analysis of fibronectin isoforms generated by alternative splicing of mRNA precursors in normal and transformed humancells
    • Borsi L, Carnemolla B, Castellani P, et al. Monocloncal antibodies in the analysis of fibronectin isoforms generated by alternative splicing of mRNA precursors in normal and transformed humancells. J Cell Biol 1987;104:595 -600.
    • (1987) J Cell Biol , vol.104 , pp. 595-600
    • Borsi, L.1    Carnemolla, B.2    Castellani, P.3
  • 56
    • 0024594936 scopus 로고
    • A tumor-associated fibronectin isoform generated by alternative splicing of messenger RNA precursors
    • Carnemolla B, Balza E, Siri A, et al. A tumor-associated fibronectin isoform generated by alternative splicing of messenger RNA precursors. J Cell Biol 1989;108:1139 -48.
    • (1989) J Cell Biol , vol.108 , pp. 1139-1148
    • Carnemolla, B.1    Balza, E.2    Siri, A.3
  • 57
    • 1042301376 scopus 로고    scopus 로고
    • The homeobox transcription factor Hox D3 promotes integrin α5β1 expression and function during angiogenesis
    • Boudreau NJ, Varner JA. The homeobox transcription factor Hox D3 promotes integrin α5β1 expression and function during angiogenesis. J Biol Chem 2004;279:4862-8.
    • (2004) J Biol Chem , vol.279 , pp. 4862-4868
    • Boudreau, N.J.1    Varner, J.A.2
  • 58
    • 0027379724 scopus 로고
    • Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectin
    • George EL, Georges-Labouesse EN, Patel-King RS, Rayburn H, Hynes RO. Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectin. Development 1993;119:1079-91.
    • (1993) Development , vol.119 , pp. 1079-1091
    • George, E.L.1    Georges-Labouesse, E.N.2    Patel-King, R.S.3    Rayburn, H.4    Hynes, R.O.5
  • 59
    • 0034721888 scopus 로고    scopus 로고
    • Regulation of integrin αvβ3- mediated endothelial cell migration and angiogenesis by integrin α5β1 and protein kinase A
    • Kim S, Harris M, Varner JA. Regulation of integrin αvβ3- mediated endothelial cell migration and angiogenesis by integrin α5β1 and protein kinase A. J Biol Chem 2000;275:33920 -8.
    • (2000) J Biol Chem , vol.275 , pp. 33920-33928
    • Kim, S.1    Harris, M.2    Varner, J.A.3
  • 61
    • 35348890874 scopus 로고    scopus 로고
    • Multiple cardiovascular defects caused by the absence of alternatively spliced segments of fibronectin
    • Astrof S, Crowley D, Hynes RO. Multiple cardiovascular defects caused by the absence of alternatively spliced segments of fibronectin. Dev Biol 2007;311:11 -24.
    • (2007) Dev Biol , vol.311 , pp. 11-24
    • Astrof, S.1    Crowley, D.2    Hynes, R.O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.