Heparin-II domain of fibronectin is a vascular endothelial growth factor-binding domain: Enhancement of VEGF biological activity by a singular growth factor/matrix protein synergism

Circulation Research

Volumn 99, Issue 8, 2006, Pages 853-860

  Wijelath, Errol S ^a,e   Rahman, Salman ^b   Namekata, Mayumi ^a   Murray, Jacqueline ^a   Nishimura, Tomoaki ^c   Mostafavi Pour, Zohreh ^d   Patel, Yatin ^b   Suda, Yasuo ^c   Humphries, Martin J ^d   Sobel, Michael ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b ST THOMAS HOSPITAL   (United Kingdom)

^c KAGOSHIMA UNIVERSITY   (Japan)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

^e Research Service (151L)   (United States)

Author keywords

Endothelial cell differentiation; Endothelial cell growth; Endothelial cells; Fibronectin; Integrins; Signal transduction; Vascular endothelial growth factor; Vascular endothelial growth factor receptors

Indexed keywords

AMINO ACID; COLLAGEN; FIBRONECTIN; HEPARIN; HEPARIN II; MATRIX PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR; VERY LATE ACTIVATION ANTIGEN 5; VITRONECTIN;

AMINO ACID SEQUENCE; ANGIOGENESIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CULTURE; CELL MIGRATION; CELL PROLIFERATION; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; TUMOR GROWTH; UMBILICAL VEIN;

BINDING SITES; BINDING, COMPETITIVE; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; DRUG SYNERGISM; ENDOTHELIAL CELLS; EXTRACELLULAR MATRIX PROTEINS; FIBRONECTINS; HEPARIN; HUMANS; PEPTIDES; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 33749676409     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000246849.17887.66     Document Type: Article

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