-
1
-
-
0027409793
-
Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producingTh cells
-
Manetti R, Parronchi P, Giudizi MG, et al. Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producingTh cells. J Exp Med. 1993;177:1199-1204.
-
(1993)
J Exp Med
, vol.177
, pp. 1199-1204
-
-
Manetti, R.1
Parronchi, P.2
Giudizi, M.G.3
-
2
-
-
0025222698
-
IL-4 directs the development of Th2-like helper effectors
-
Swain SL, Weinberg AD, English M, Huston G. IL-4 directs the development of Th2-like helper effectors. J Immunol. 1990;145:3796-3806.
-
(1990)
J Immunol
, vol.145
, pp. 3796-3806
-
-
Swain, S.L.1
Weinberg, A.D.2
English, M.3
Huston, G.4
-
3
-
-
0029876629
-
Stat6 is required for mediating responses to IL-4 and for development of Th2 cells
-
Kaplan MH, Schindler U, Smiley ST, Grusby MJ. Stat6 is required for mediating responses to IL-4 and for development of Th2 cells. Immunity. 1996;4:313-319.
-
(1996)
Immunity
, vol.4
, pp. 313-319
-
-
Kaplan, M.H.1
Schindler, U.2
Smiley, S.T.3
Grusby, M.J.4
-
4
-
-
0028799945
-
Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ Tcells
-
Constant S, Pfeiffer C, Woodard A, Pasqualini T, Bottomly K. Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ Tcells. J Exp Med. 1995;182:1591-1596.
-
(1995)
J Exp Med
, vol.182
, pp. 1591-1596
-
-
Constant, S.1
Pfeiffer, C.2
Woodard, A.3
Pasqualini, T.4
Bottomly, K.5
-
5
-
-
0036457072
-
TSST-1 induces Th1 orTh2 differentiation in naive CD4+ T cells in a dose-and APC-dependent manner
-
Brandt K, van der Bosch J, Fliegert R, Gehring S. TSST-1 induces Th1 orTh2 differentiation in naive CD4+ T cells in a dose-and APC-dependent manner. Scand J Immunol. 2002;56:572-579.
-
(2002)
Scand J Immunol
, vol.56
, pp. 572-579
-
-
Brandt, K.1
van der Bosch, J.2
Fliegert, R.3
Gehring, S.4
-
6
-
-
0030903695
-
Differential ability of T cell subsets to undergo activation-induced cell death
-
VaradhacharyAS, Perdow SN, Hu C, Ramanarayanan M, Salgame P. Differential ability of T cell subsets to undergo activation-induced cell death. Proc Natl Acad Sci USA. 1997;94: 5778-5783.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 5778-5783
-
-
Varadhachary, A.S.1
Perdow, S.N.2
Hu, C.3
Ramanarayanan, M.4
Salgame, P.5
-
7
-
-
0036133110
-
Stat6 and IRS-2 cooperate in interleukin 4 (IL-4)-induced proliferation and differentiation but are dispensable for IL-4-dependent rescue from apoptosis
-
Wurster AL, Withers DJ, UchidaT, White MF, Grusby MJ. Stat6 and IRS-2 cooperate in interleukin 4 (IL-4)-induced proliferation and differentiation but are dispensable for IL-4-dependent rescue from apoptosis. Mol Cell Biol. 2002;22: 117-126.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 117-126
-
-
Wurster, A.L.1
Withers, D.J.2
Uchida, T.3
White, M.F.4
Grusby, M.J.5
-
8
-
-
33847611217
-
Interleukin-4 inhibits caspase-3 by regulating several proteins in the Fas pathway during initial stages of human T helper 2 cell differentiation
-
Rautajoki KJ, Marttila EM, Nyman TA, Lahesmaa R. Interleukin-4 inhibits caspase-3 by regulating several proteins in the Fas pathway during initial stages of human T helper 2 cell differentiation. Mol Cell Proteomics. 2007;6:238-251.
-
(2007)
Mol Cell Proteomics
, vol.6
, pp. 238-251
-
-
Rautajoki, K.J.1
Marttila, E.M.2
Nyman, T.A.3
Lahesmaa, R.4
-
9
-
-
0037178853
-
Interleukin-4-mediated protection of primary B cells from apoptosis through Stat6-dependent up-regulation of Bcl-xL
-
Wurster AL, Rodgers VL, White MF, Rothstein TL, Grusby MJ. Interleukin-4-mediated protection of primary B cells from apoptosis through Stat6-dependent up-regulation of Bcl-xL. J Biol Chem. 2002;277:27169-27175.
-
(2002)
J Biol Chem
, vol.277
, pp. 27169-27175
-
-
Wurster, A.L.1
Rodgers, V.L.2
White, M.F.3
Rothstein, T.L.4
Grusby, M.J.5
-
10
-
-
0344761969
-
IL-4 inhibits apoptosis and prevents mitochondrial damage without inducing the switch to necrosis observed with caspase inhibitors
-
Lemaire C, Andréau K, Fraisse CS, Adam A, Souvannavong V. IL-4 inhibits apoptosis and prevents mitochondrial damage without inducing the switch to necrosis observed with caspase inhibitors. Cell Death Differ. 1999;6:813-820.
-
(1999)
Cell Death Differ
, vol.6
, pp. 813-820
-
-
Lemaire, C.1
Andréau, K.2
Fraisse, C.S.3
Adam, A.4
Souvannavong, V.5
-
11
-
-
33744546660
-
Signaling mechanisms, interaction partners, and target genes of STAT6
-
Hebenstreit D, Wirnsberger G, Horejs-Hoeck J, Duschl A. Signaling mechanisms, interaction partners, and target genes of STAT6. Cytokine Growth Factor Rev. 2006;17:173-188.
-
(2006)
Cytokine Growth Factor Rev
, vol.17
, pp. 173-188
-
-
Hebenstreit, D.1
Wirnsberger, G.2
Horejs-Hoeck, J.3
Duschl, A.4
-
12
-
-
0141676377
-
Stat6-protease but not Stat5-protease is inhibited by an elastase inhibitor ONO-5046
-
Suzuki K, Nakajima H, Ikeda K, et al. Stat6-protease but not Stat5-protease is inhibited by an elastase inhibitor ONO-5046. Biochem Biophys Res Commun. 2003;309:768-773.
-
(2003)
Biochem Biophys Res Commun
, vol.309
, pp. 768-773
-
-
Suzuki, K.1
Nakajima, H.2
Ikeda, K.3
-
13
-
-
14044278782
-
Proteolytic regulation of activated STAT6 by calpains
-
Zamorano J, Rivas MD, Setien F, Perez-G M. Proteolytic regulation of activated STAT6 by calpains. J Immunol. 2005;174:2843-2848.
-
(2005)
J Immunol
, vol.174
, pp. 2843-2848
-
-
Zamorano, J.1
Rivas, M.D.2
Setien, F.3
Perez-G, M.4
-
15
-
-
0034055253
-
PRELI, the human homologue of the avian px19, is expressed by germinal center B lymphocytes
-
Guzman-Rojas L, Sims JC, Rangel R, et al. PRELI, the human homologue of the avian px19, is expressed by germinal center B lymphocytes. Int Immunol. 2000;12:607-612.
-
(2000)
Int Immunol
, vol.12
, pp. 607-612
-
-
Guzman-Rojas, L.1
Sims, J.C.2
Rangel, R.3
-
16
-
-
1642505380
-
PRELI (protein of relevant evolutionary and lymphoid interest) is located within an evolutionarily conserved gene cluster on chromosome 5q34-q35 and encodes a novel mitochondrial protein
-
Fox EJ, Stubbs SA, Kyaw Tun J, Leek JP, Markham AF, Wright SC. PRELI (protein of relevant evolutionary and lymphoid interest) is located within an evolutionarily conserved gene cluster on chromosome 5q34-q35 and encodes a novel mitochondrial protein. Biochem J. 2004; 378:817-825.
-
(2004)
Biochem J
, vol.378
, pp. 817-825
-
-
Fox, E.J.1
Stubbs, S.A.2
Kyaw Tun, J.3
Leek, J.P.4
Markham, A.F.5
Wright, S.C.6
-
17
-
-
0036017758
-
Induction of autophagy causes dramatic changes in the subcellular distribution of GFP-Rab24
-
Munafo DB, Colombo MI. Induction of autophagy causes dramatic changes in the subcellular distribution of GFP-Rab24. Traffic. 2002;3:472-482.
-
(2002)
Traffic
, vol.3
, pp. 472-482
-
-
Munafo, D.B.1
Colombo, M.I.2
-
18
-
-
33644851858
-
Enrichment of nucleofected primary human CD4+ T cells: A novel and efficient method for studying gene function and role in human primary T helper cell differentiation
-
Tahvanainen J, Pykalainen M, KallonenT Lahteenmaki H, Rasool O, Lahesmaa R. Enrichment of nucleofected primary human CD4+ T cells: a novel and efficient method for studying gene function and role in human primary T helper cell differentiation. J Immunol Methods. 2006; 310:30-39.
-
(2006)
J Immunol Methods
, vol.310
, pp. 30-39
-
-
Tahvanainen, J.1
Pykalainen, M.2
KallonenT Lahteenmaki, H.3
Rasool, O.4
Lahesmaa, R.5
-
19
-
-
0142121516
-
Exploration, normalization, and summaries of high density oligonucleotide array probe level data
-
Irizarry RA, Hobbs B, Collin F, et al. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics. 2003;4:249-264.
-
(2003)
Biostatistics
, vol.4
, pp. 249-264
-
-
Irizarry, R.A.1
Hobbs, B.2
Collin, F.3
-
20
-
-
0038744380
-
Kinetics and STAT4-or STAT6-mediated regulation of genes involved in lymphocyte polarization to Th1 and Th2 cells
-
Lund RJ, Ylikoski EK, AittokallioT, Nevalainen O, Lahesmaa R. Kinetics and STAT4-or STAT6-mediated regulation of genes involved in lymphocyte polarization to Th1 and Th2 cells. Eur J Immunol. 2003;33:1105-1116.
-
(2003)
Eur J Immunol
, vol.33
, pp. 1105-1116
-
-
Lund, R.J.1
Ylikoski, E.K.2
Aittokallio, T.3
Nevalainen, O.4
Lahesmaa, R.5
-
21
-
-
0035577641
-
Identification and validation of endogenous reference genes for expression profiling of T helper cell differentiation by quantitative real-time RT-PCR
-
Hamalainen HK, Tubman JC, Vikman S, et al. Identification and validation of endogenous reference genes for expression profiling of T helper cell differentiation by quantitative real-time RT-PCR. Anal Biochem. 2001;299:63-70.
-
(2001)
Anal Biochem
, vol.299
, pp. 63-70
-
-
Hamalainen, H.K.1
Tubman, J.C.2
Vikman, S.3
-
22
-
-
35748946524
-
Redox regulation of apoptosis before and after cytochrome c release
-
Chen Q, Crosby M, Almasan A. Redox regulation of apoptosis before and after cytochrome c release. Korean J Biol Sci. 2003;7:1-9.
-
(2003)
Korean J Biol Sci
, vol.7
, pp. 1-9
-
-
Chen, Q.1
Crosby, M.2
Almasan, A.3
-
23
-
-
0036839331
-
Caspase-independent phosphatidylserine exposure during apoptosis of primary T lymphocytes
-
Ferraro-Peyret C, Quemeneur L, Flacher M, Revillard JP, Genestier L. Caspase-independent phosphatidylserine exposure during apoptosis of primary T lymphocytes. J Immunol. 2002;169: 4805-4810.
-
(2002)
J Immunol
, vol.169
, pp. 4805-4810
-
-
Ferraro-Peyret, C.1
Quemeneur, L.2
Flacher, M.3
Revillard, J.P.4
Genestier, L.5
-
24
-
-
0038731167
-
Caspase-independent cell death in T lymphocytes
-
Jaattela M, Tschopp J. Caspase-independent cell death in T lymphocytes. Nat Immunol. 2003;4: 416-423.
-
(2003)
Nat Immunol
, vol.4
, pp. 416-423
-
-
Jaattela, M.1
Tschopp, J.2
-
25
-
-
0029839059
-
-
SornasseT, Larenas PV, Davis KA, de Vries JE, Yssel H. Differentiation and stability of T helper 1 and 2 cells derived from naive human neonatal CD4+ T cells, analyzed at the single-cell level. J Exp Med. 1996;184:473-483.
-
SornasseT, Larenas PV, Davis KA, de Vries JE, Yssel H. Differentiation and stability of T helper 1 and 2 cells derived from naive human neonatal CD4+ T cells, analyzed at the single-cell level. J Exp Med. 1996;184:473-483.
-
-
-
-
26
-
-
0033784440
-
CRTH2 is the most reliable marker for the detection of circulating human type 2 Th and type 2 T cytotoxic cells in health and disease
-
Cosmi L, Annunziato F, Galli MIG, Maggi RME, Nagata K, Romagnani S. CRTH2 is the most reliable marker for the detection of circulating human type 2 Th and type 2 T cytotoxic cells in health and disease. Eur J Immunol. 2000;30:2972-2979.
-
(2000)
Eur J Immunol
, vol.30
, pp. 2972-2979
-
-
Cosmi, L.1
Annunziato, F.2
Galli, M.I.G.3
Maggi, R.M.E.4
Nagata, K.5
Romagnani, S.6
-
27
-
-
34248349587
-
GATA3 up-regulation associated with surface expression of CD294/CRTH2: A unique feature of human Th cells
-
De Fanis U, Mori F, Kurnat RJ, et al. GATA3 up-regulation associated with surface expression of CD294/CRTH2: a unique feature of human Th cells. Blood. 2007;109:4343-4350.
-
(2007)
Blood
, vol.109
, pp. 4343-4350
-
-
De Fanis, U.1
Mori, F.2
Kurnat, R.J.3
-
28
-
-
0033984684
-
Activation of calpain precedes morphologic alterations during hydrogen peroxide-induced apoptosis in neuronally differentiated mouse embryonal carcinoma P19 cell line
-
Ishihara I, Minami Y, NishizakiT, MatsuokaT, Yamamura H. Activation of calpain precedes morphologic alterations during hydrogen peroxide-induced apoptosis in neuronally differentiated mouse embryonal carcinoma P19 cell line. Neurosci Lett. 2000;279:97-100.
-
(2000)
Neurosci Lett
, vol.279
, pp. 97-100
-
-
Ishihara, I.1
Minami, Y.2
Nishizaki, T.3
Matsuoka, T.4
Yamamura, H.5
-
29
-
-
0036070773
-
Oxidative stress decreases G protein-coupled receptor kinase 2 in lymphocytes via a calpain-dependent mechanism
-
Lombardi MS, Kavelaars A, Penela P, et al. Oxidative stress decreases G protein-coupled receptor kinase 2 in lymphocytes via a calpain-dependent mechanism. Mol Pharmacol. 2002;62:379-388.
-
(2002)
Mol Pharmacol
, vol.62
, pp. 379-388
-
-
Lombardi, M.S.1
Kavelaars, A.2
Penela, P.3
-
30
-
-
0030569550
-
Modulation of the calpain autopro-teolysis by calpastatin and phospholipids
-
Melloni E, Michetti M, Salamino F, Minafra R, Pontremoli S. Modulation of the calpain autopro-teolysis by calpastatin and phospholipids. Biochem Biophys Res Commun. 1996;229:193-197.
-
(1996)
Biochem Biophys Res Commun
, vol.229
, pp. 193-197
-
-
Melloni, E.1
Michetti, M.2
Salamino, F.3
Minafra, R.4
Pontremoli, S.5
-
31
-
-
33747422544
-
Ups1p, a conserved intermembrane space protein, regulates mitochondrial shape and alternative topogenesis of Mgm1p
-
Sesaki H, Dunn CD, Iijima M, et al. Ups1p, a conserved intermembrane space protein, regulates mitochondrial shape and alternative topogenesis of Mgm1p. J Cell Biol. 2006;173:651-658.
-
(2006)
J Cell Biol
, vol.173
, pp. 651-658
-
-
Sesaki, H.1
Dunn, C.D.2
Iijima, M.3
-
32
-
-
0037424239
-
Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis
-
Olichon A, Baricault L, Gas N, et al. Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis. J Biol Chem. 2003;278: 7743-7746.
-
(2003)
J Biol Chem
, vol.278
, pp. 7743-7746
-
-
Olichon, A.1
Baricault, L.2
Gas, N.3
-
33
-
-
33745699393
-
OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion
-
Frezza C, Cipolat S, Martins de Brito O, et al. OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion. Cell. 2006; 126:177-189.
-
(2006)
Cell
, vol.126
, pp. 177-189
-
-
Frezza, C.1
Cipolat, S.2
Martins de Brito, O.3
-
34
-
-
33947434544
-
OPA1 alternate splicing uncouples an evolutionary conserved function in mitochondrial fusion from a vertebrate restricted function in apoptosis
-
Olichon A, Elachouri G, Baricault L, Delettre C, Belenguer P, Lenaers G. OPA1 alternate splicing uncouples an evolutionary conserved function in mitochondrial fusion from a vertebrate restricted function in apoptosis. Cell Death Differ. 2007;14: 682-692.
-
(2007)
Cell Death Differ
, vol.14
, pp. 682-692
-
-
Olichon, A.1
Elachouri, G.2
Baricault, L.3
Delettre, C.4
Belenguer, P.5
Lenaers, G.6
-
35
-
-
34548313686
-
Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage
-
Griparic L, Kanazawa T, van der Bliek AM. Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage. J Cell Biol. 2007; 178:757-764.
-
(2007)
J Cell Biol
, vol.178
, pp. 757-764
-
-
Griparic, L.1
Kanazawa, T.2
van der Bliek, A.M.3
-
36
-
-
0030002451
-
Proteolytic cleavage of alpha-actinin by calpain in T cells stimulated with anti-CD3 monoclonal antibody
-
Selliah N, Brooks WH, Roszman TL. Proteolytic cleavage of alpha-actinin by calpain in T cells stimulated with anti-CD3 monoclonal antibody. J Immunol. 1996;156:3215-3221.
-
(1996)
J Immunol
, vol.156
, pp. 3215-3221
-
-
Selliah, N.1
Brooks, W.H.2
Roszman, T.L.3
-
37
-
-
0031455169
-
Calcium-dependent signaling pathways in T cells: Potential role of calpain, protein tyrosine phosphatase 1b, and p130Cas in integrin-mediated signaling events
-
Rock MT, Brooks WH, Roszman TL. Calcium-dependent signaling pathways in T cells: potential role of calpain, protein tyrosine phosphatase 1b, and p130Cas in integrin-mediated signaling events. J Biol Chem. 1997;272:33377-33383.
-
(1997)
J Biol Chem
, vol.272
, pp. 33377-33383
-
-
Rock, M.T.1
Brooks, W.H.2
Roszman, T.L.3
-
38
-
-
0034651940
-
The balance of protein kinase C and calcium signaling directs T cell subset development
-
Noble A, Truman JP, Vyas B, Vukmanovic-Stejic M, Hirst WJ, Kemeny DM. The balance of protein kinase C and calcium signaling directs T cell subset development. J Immunol. 2000;164:1807-1813.
-
(2000)
J Immunol
, vol.164
, pp. 1807-1813
-
-
Noble, A.1
Truman, J.P.2
Vyas, B.3
Vukmanovic-Stejic, M.4
Hirst, W.J.5
Kemeny, D.M.6
-
39
-
-
35448961570
-
Increased calpain correlates with Th1 cytokine profile in PBMCs from MS patients
-
Imam SA, Guyton MK, HaqueA, et al. Increased calpain correlates with Th1 cytokine profile in PBMCs from MS patients. J Neuroimmunol. 2007; 190:139-145.
-
(2007)
J Neuroimmunol
, vol.190
, pp. 139-145
-
-
Imam, S.A.1
Guyton, M.K.2
HaqueA3
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