IL-4 inhibits apoptosis and prevents mitochondrial damage without inducing the switch to necrosis observed with caspase inhibitors

Cell Death and Differentiation

Volumn 6, Issue 8, 1999, Pages 813-820

  Lemaire, Christophe ^a   Andréau, Karine ^a   Sidoti De Fraisse, Carole ^b   Adam, Arlette ^a   Souvannavong, Vongthip ^a  

^a INSTITUTE FOR INTEGRATIVE BIOLOGY OF THE CELL I2BC   (France)

^b CNRS   (France)

Author keywords

Apoptosis; Dexamethasone; Interleukin 4; Mitochondria; Murine B cells; Necrosis

Indexed keywords

CASPASE INHIBITOR; INTERLEUKIN 4;

ANIMAL CELL; APOPTOSIS; ARTICLE; B LYMPHOCYTE; CELL DAMAGE; CELL DEATH; CELL MEMBRANE POTENTIAL; CELL VIABILITY; CONTROLLED STUDY; MITOCHONDRION; MOUSE; NECROSIS; NONHUMAN; PRIORITY JOURNAL; THYMOCYTE;

EID: 0344761969     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4400556     Document Type: Article

References (45)

1. Raff M (1998) Cell suicide for beginners. Nature 396: 119-122
2. Golstein P, Ojcius DM and Young JD-E (1991) Cell death mechanisms and the immune system. Immunol. Rev. 121: 29-65
3. Cohen JJ, Duke RC, Fadok VA and Sellins KS (1992) Apoptosis and programmed cell death in immunity. Annu. Rev. Immunol. 10: 267-293
4. Kerr JFR, Wyllie AH and Currie AR (1972) Apoptosis: a basic biological phenomenon with wide ranging implications in tissue kinetics. Brit. J. Cancer 26: 239-257
5. Wyllie AH, Kerr JFR and Currie AR (1980) Cell death: the signifiance of apoptosis. Int. Rev. Cytol. 68: 251-305
6. Darzynkiewicz Z, Juan G, Li X, Gorczyca W, Murakami T and Traganos F (1997) Cytometry in cell necrobiology: Analysis of apoptosis and accidental cell death (Necrosis). Cytometry 27: 1-20
7. Alnemri ES (1997) Mammalian cell death proteases: A family of highly conserved aspartate specific cysteine proteases. J. Cell. Biochem. 64: 33-42
8. Cohen GM (1997) Caspases: the executioners of apoptosis. Biochem. J. 326: 1-16
9. Thompson CB (1998) Apoptosis in the pathogenesis and treatment of disease. Science 267: 1456-1462
10. Thornberry NA and Lazebnik Y (1998) Caspases: Enemies within. Science 281: 1312-1316
11. Kroemer G, Zamzami N and Susin SA (1997) Mitochondrial control of apoptosis. Immunol. Today 18: 44-51
12. Green D and Kroemer G (1998) The central executioners of apoptosis: caspases or mitochondria? Trends Cell Biol. 8: 267-271
13. Mignotte B and Vayssiere JL (1998) Mitochondria and apoptosis. Eur. J. Biochem. 252: 1-15
14. Bossy-Wetzel E, Newmeyer DD and Green DR (1998) Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization. EMBO J. 17: 37-49
15. Green DR (1998) Apoptotic pathways: The roads to ruin. Cell 94: 695-698
16. Zamzami N, Susin SA, Marchetti P, Hirsch T, Gomez Monterrey I, Castedo M and Kroemer G (1996) Mitochondrial control of nuclear apoptosis. J Exp. Med. 183: 1533-1544
17. Longthorne VL and Williams GT (1997) Caspase activity is required for commitment to Fas-mediated apoptosis. EMBOJ. 16: 3805-3812
18. McCarthy NJ, Whyte MK, Gilbert CS and Evan GI (1997) Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak. J. Cell. Biol. 136: 215-227
19. Ohta T, Kinoshita T, Naito M, Nozaki T, Masutani M, Tsuruo T and Miyajima A (1997) Requirement of caspase-3/CPP32 protease cascade for apoptotic death following cytokine deprivation in haematopoietic cells. J. Biol. Chem. 272: 23111-23116
20. Kroemer G, Dallaporta B and Rescherigon M (1998) The mitochondrial death/life regulator in apoptosis and necrosis. Annu. Rev. Physiol. 60: 619-642
21. Lemaire C, Andréau K, Souvannavong V and Adam A (1998) Inhibition of caspase activity induces a switch from apoptosis to necrosis. FEBS Lett. 425: 266-270
22. Green DR and Reed JC (1998) Mitochondria and apoptosis. Science 281: 1309-1312
23. Illera VA, Perandones CE, Stunz LL, Mower DAJ and Ashman RF (1993) Apoptosis in splenic B lymphocytes. Regulation by protein kinase C and IL-4. J. Immunol. 151: 2965-2973
24. Baixeras E, Bosca L, Stauber C, Gonzalez A, Carrera AC, Gonzalo JA and Martineza C (1994) From apoptosis to autoimmunity: Insights from the signaling pathways leading to proliferation or to programmed cell death. Immunol. Rev. 142: 53-91
25. Paul WE (1991) Interleukin 4: a prototypic immunoregulatory lymphokine. Blood 77: 1859-1870
26. Norvell A, Mandik L and Monroe JG (1995) Engagement of the antigen-receptor on immature murine B lymphocytes results in death by apoptosis. J. Immunol. 154: 4404-4413
27. Souvannavong V, Lemaire C, Andréau K, Brown S and Adam A (1998) Age-associated modulation of apoptosis and activation in murine B lymphocytes. Mech. Ageing Dev. 103: 285-299
28. Bellosillo B, Dalmau M, Colomer D and Gil J (1997) Involvement of CED-3/ICE proteases in the apoptosis of B-chronic lymphocytic leukemia cells. Blood 89: 3378-3384
29. Parry SL, Hasbold J, Holman M and Klaus GGB (1994) Hypercross-linking surface IgM or IgD receptors on mature B cells induces apoptosis that is reversed by costimulation with IL-4 and anti-CD40. J. Immunol. 152: 2821-2829
30. Foote LC, Howard RG, Marshakrothstein Aand Rothstein TL (1996) IL-4 induces Fas resistance in B cells. J. Immunol. 157: 2749-2753
31. Hirsch T, Marchetti P, Susin SA, Dallaporta B, Zamzami N, Marzo I, Geuskens M and Kroemer G (1997) The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death. Oncogene 15: 1573-1581
32. Nicholson DW, All A, Thornberry NA, Vaillancourt JP, Ding CK, Gallant M, Gareau Y, Griffin PR, Labelle M, Lazebnik YA, Munday NA, Raju SM, Smulson ME, Yamin T, Yu VL and Miller DK (1995) Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature 376: 37-43
33. Zamorano J, Wang HY, Wang LM, Pierce JH and Keegan AD (1996) II-4 protects cells from apoptosis via the insulin receptor substrate pathway and a second independent signaling pathway. J. Immunol. 157: 4926-4934
34. He HL, Hershberger PA and McCarthy SA (1998) Down-modulation of a novel Bax-associated protein during apoptosis in normal mature B lymphocytes. J. Immunol. 161: 1176-1182
35. Beaver JP and Waring P (1995) A decrease in intracellular glutathione concentration precedes the onset of apoptosis in murine thymocytes. Eur. J. Cell Biol. 68: 47-54
36. Marchetti P, Hirsch T, Zamzami N, Castedo M, Decaudin D, Susin SA, Masse B and KroemerG (1996) Mitochondrial permeability transition triggers lymphocyte apoptosis. J. Immunol. 157: 4830-4836
37. Hirsch T, Dallaporta B, Zamzami N, Susin SA, Ravagnan L, Marzo I, Brenner C and Kroemer G (1998) Proteasome activation occurs at an early, premitochondrial step of thymocyte apoptosis. J. Immunol. 161: 35-40
38. Boise LH and Thompson CB (1996) Hierarchical control of lymphocyte survival. Science 274: 67-68
39. Armstrong RC, Aja TJ, Hoang KD, Gaur S, Bai X, Alnemri ES, Litwack G, Karanewsky DS, Fritz LC and Tomaselli KJ (1997) Activation of the CED3/ICE-related protease CPP32 in cerebellar granule neurons undergoing apoptosis but not necrosis. J. Neurosci. 17: 553-562
40. Amarantemendes GP, Finucane DM, Martin SJ, Cotter TG, Salvesen GS and Green DR (1998) Anti-apoptotic oncogenes prevent caspase-dependent and independent commitment for cell death. Cell Death Differ. 5: 298-306
41. Hirata H, Takahashi A, Kobayashi S, Yonehara S, Sawai H, Okazaki T, Yamamoto K and Sasada M (1998) Caspases are activated in a branched protease cascade and control distinct downstream processes in Fas-induced apoptosis. J. Exp. Med. 187: 587-600
42. Marzo I, BrennerC, Zamzami N, Susin SA, Beutner G, Brdiczka D, Remy R, Xie ZH, Reed JC and Kroemer G (1998) The permeability transition pore complex: A target for apoptosis regulation by caspases and Bcl-2-related proteins. J. Exp. Med. 187: 1261-1271
43. Jones KH and Senft JA (1985) An improved method to determine cell viability by simultaneous staining with fluorescein diacetate-propidium iodide. J. Histochem. Cytochem. 33: 77-79
44. Sarih M, Souvannavong V and Adam A (1993) Nitric oxide synthase induces macrophage death by apoptosis. Biochem. Biophys. Res. Commun. 191: 503-508
45. Sidoti-de Fraisse C, Rincheval V, Risler Y, Mignotte B and Vayssiere JL (1998) TNF-alpha activates at least two apoptotic signaling cascades. Oncogene 17: 1639-1651