Phosphatidylinositol 3-kinase (PI-3K)/Akt but not PI-3K/p70 S6 kinase signaling mediates IGF-1-promoted lens epithelial cell survival

Investigative Ophthalmology and Visual Science

Volumn 45, Issue 10, 2004, Pages 3577-3588

  Chandrasekher, Gudiseva ^a,b   Sailaja, Dasetty ^a  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b LSU EYE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; CASPASE 3; DNA FRAGMENT; DYE; FUGENE 6; GENOMIC DNA; INSULIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAD; PROTEIN BCL 2; RAPAMYCIN; REAGENT; S6 KINASE; SOMATOMEDIN C; STAUROSPORINE; UNCLASSIFIED DRUG; WORTMANNIN;

AKT GENE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL NUCLEUS; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DNA BINDING; DNA DEGRADATION; DOSE RESPONSE; ENZYME ACTIVATION; ENZYME INACTIVATION; EPITHELIUM CELL; FLUORESCENCE; GENE; GENE OVEREXPRESSION; GENETIC TRANSFECTION; IMMUNOBLOTTING; LENS EPITHELIUM; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RABBIT; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; BCL-ASSOCIATED DEATH PROTEIN; BLOTTING, WESTERN; CARRIER PROTEINS; CASPASE 3; CASPASES; CELL DIVISION; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, AGAR GEL; EPITHELIAL CELLS; GENETIC VECTORS; INSULIN; INSULIN-LIKE GROWTH FACTOR I; LENS, CRYSTALLINE; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RABBITS; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIGNAL TRANSDUCTION; STAUROSPORINE; TRANSFECTION;

EID: 4644254018     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.04-0279     Document Type: Article

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