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Volumn 393, Issue 5, 2009, Pages 1525-1530
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Ultrasensitive method for the determination of 4-hydroxy-1-(3-pyridyl)-1- butanone-releasing DNA adducts by gas chromatography-high resolution mass spectrometry in mucosal biopsies of the lower esophagus
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Author keywords
DNA adducts; Esophagus; High resolution GC NCI HRMS; Tobacco specific nitrosamines
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Indexed keywords
ANALYTICAL METHODS;
BIOPSY SAMPLES;
CAPILLARY GAS CHROMATOGRAPHIES;
COEFFICIENTS OF VARIATIONS;
DNA ADDUCTS;
ESOPHAGUS;
HIGH RESOLUTION MASS SPECTROMETRIES;
HIGH-RESOLUTION GC-NCI-HRMS;
INTERNATIONAL AGENCY FOR RESEARCH ON CANCERS;
LIMIT OF DETECTIONS;
LIMIT OF QUANTIFICATIONS;
METABOLIC ACTIVATIONS;
NEGATIVE CHEMICAL IONIZATION MODES;
PYRIDYL;
TARGET TISSUES;
TOBACCO-SPECIFIC NITROSAMINES;
ULTRASENSITIVE;
BIOPSY;
CHROMATOGRAPHIC ANALYSIS;
DNA;
GAS CHROMATOGRAPHY;
GENES;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
INTERNATIONAL COOPERATION;
IONIZATION OF GASES;
MASS SPECTROMETERS;
MASS SPECTROMETRY;
NITROSAMINES;
TOBACCO;
NUCLEIC ACIDS;
4 HYDROXY 1 (3 PYRIDYL) 1 BUTANONE;
4-HYDROXY-1-(3-PYRIDYL)-1-BUTANONE;
ALKANONE;
PYRIDINE DERIVATIVE;
ADULT;
AGED;
ARTICLE;
BIOPSY;
DNA ADDUCT;
ESOPHAGUS;
FEMALE;
HUMAN;
MALE;
MASS FRAGMENTOGRAPHY;
METABOLISM;
MIDDLE AGED;
MUCOSA;
ADULT;
AGED;
BIOPSY;
BUTANONES;
DNA ADDUCTS;
ESOPHAGUS;
FEMALE;
GAS CHROMATOGRAPHY-MASS SPECTROMETRY;
HUMANS;
MALE;
MIDDLE AGED;
MUCOUS MEMBRANE;
PYRIDINES;
NICOTIANA TABACUM;
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EID: 60749099653
PISSN: 16182642
EISSN: 16182650
Source Type: Journal
DOI: 10.1007/s00216-008-2566-y Document Type: Article |
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Times cited : (13)
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References (35)
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