Mass spectrometric analysis of 4-hydroxy-1-(3-pyridyl)-1-butanone-releasing DNA adducts in human lung

Toxicology

Volumn 232, Issue 3, 2007, Pages 277-285

  Hölzle, Daniel ^a   Schlöbe, Daniela ^a   Tricker, Anthony R ^b   Richter, Elmar ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b Philip Morris Products SA   (Switzerland)

Author keywords

DNA adducts; Hemoglobin adducts; Human lung; Smoking; Tobacco specific nitrosamines

Indexed keywords

2 BUTANONE; 4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; 4 HYDROXY 1 (3 PYRIDYL) 1 BUTANONE; DNA; HEMOGLOBIN; NITROSAMINE; NITROSONORNICOTINE; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; DNA ADDUCT; FEMALE; GAS CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; HYDROLYSIS KINETICS; LUNG CANCER; MALE; MASS SPECTROMETRY; PRIORITY JOURNAL; SELF REPORT; SMOKING; TOBACCO;

ADENOCARCINOMA; AGED; AGED, 80 AND OVER; BUTANONES; CARCINOMA, SQUAMOUS CELL; DNA ADDUCTS; FEMALE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HEMOGLOBINS; HUMANS; LUNG; LUNG NEOPLASMS; MALE; MIDDLE AGED; PYRIDINES; SENSITIVITY AND SPECIFICITY; SMOKING;

NICOTIANA TABACUM;

EID: 33947331376     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2007.01.016     Document Type: Article

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