-
2
-
-
33644618433
-
The biology of incretin hormones
-
Drucker D.J. The biology of incretin hormones. Cell Metabolism 3 (2006) 153-165
-
(2006)
Cell Metabolism
, vol.3
, pp. 153-165
-
-
Drucker, D.J.1
-
3
-
-
0022617246
-
Reduced incretin effect in type 2 (non-insulin-dependent) diabetes
-
Nauck M., Stöckmann F., Ebert R., et al. Reduced incretin effect in type 2 (non-insulin-dependent) diabetes. Diabetologia 29 (1986) 46-54
-
(1986)
Diabetologia
, vol.29
, pp. 46-54
-
-
Nauck, M.1
Stöckmann, F.2
Ebert, R.3
-
4
-
-
1842855423
-
Incretins, insulin secretion and type-2 diabetes mellitus
-
Vilsboll T., and Holst J.J. Incretins, insulin secretion and type-2 diabetes mellitus. Diabetologia 47 (2004) 357-366
-
(2004)
Diabetologia
, vol.47
, pp. 357-366
-
-
Vilsboll, T.1
Holst, J.J.2
-
5
-
-
3242730474
-
Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans
-
Holst J.J., and Gromada J. Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans. American Journal of Physiology 287 (2004) E199-E206
-
(2004)
American Journal of Physiology
, vol.287
-
-
Holst, J.J.1
Gromada, J.2
-
6
-
-
15044341261
-
What do we know about the secretion and degradation of incretin hormones?
-
Deacon C.F. What do we know about the secretion and degradation of incretin hormones?. Regulatory Peptides 128 (2006) 117-124
-
(2006)
Regulatory Peptides
, vol.128
, pp. 117-124
-
-
Deacon, C.F.1
-
7
-
-
12244281855
-
Circulation and degradation of GIP and GLP-I
-
Deacon C.F. Circulation and degradation of GIP and GLP-I. Hormone and Metabolic Research 36 (2004) 761-765
-
(2004)
Hormone and Metabolic Research
, vol.36
, pp. 761-765
-
-
Deacon, C.F.1
-
8
-
-
12244305595
-
New insights concerning the glucose-dependent insulin secretagogue action of glucagon-like peptide-I in pancreatic β-cells
-
Holz G. New insights concerning the glucose-dependent insulin secretagogue action of glucagon-like peptide-I in pancreatic β-cells. Hormone and Metabolic Research 36 (2004) 787-794
-
(2004)
Hormone and Metabolic Research
, vol.36
, pp. 787-794
-
-
Holz, G.1
-
9
-
-
0033513455
-
Exendin 4 stimulates both β-cell replication and neogenesis, resulting in increased β-cell mass and improved glucose tolerance in diabetic rats
-
Xu G., Stoffers D.A., Habener J.F., et al. Exendin 4 stimulates both β-cell replication and neogenesis, resulting in increased β-cell mass and improved glucose tolerance in diabetic rats. Diabetes 48 (1999) 2270-2276
-
(1999)
Diabetes
, vol.48
, pp. 2270-2276
-
-
Xu, G.1
Stoffers, D.A.2
Habener, J.F.3
-
10
-
-
0036828227
-
Glucagon-like peptide-I promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats
-
Farilla L., Hui H., Bertolotto C., et al. Glucagon-like peptide-I promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats. Endocrinology 143 (2002) 4397-4408
-
(2002)
Endocrinology
, vol.143
, pp. 4397-4408
-
-
Farilla, L.1
Hui, H.2
Bertolotto, C.3
-
11
-
-
12244264206
-
The role of GLP-I in the life and death of pancreatic beta cells
-
Perfetti R., and Hui H. The role of GLP-I in the life and death of pancreatic beta cells. Hormone and Metabolic Research 36 (2004) 804-810
-
(2004)
Hormone and Metabolic Research
, vol.36
, pp. 804-810
-
-
Perfetti, R.1
Hui, H.2
-
12
-
-
0034032317
-
Insulinotropic glucagon-like peptide I agonists stimulate expression of homeodomain protein IDX-I and increase islet size in mouse pancreas
-
Stoffers D.A., Kieffer T.J., Hussain M.A., et al. Insulinotropic glucagon-like peptide I agonists stimulate expression of homeodomain protein IDX-I and increase islet size in mouse pancreas. Diabetes 49 (2000) 741-748
-
(2000)
Diabetes
, vol.49
, pp. 741-748
-
-
Stoffers, D.A.1
Kieffer, T.J.2
Hussain, M.A.3
-
13
-
-
0038574573
-
Gastric inhibitory polypeptide (GIP) dose-dependently stimulates glucagon secretion in healthy human subjects at euglycemia
-
Meier J.J., Gallwitz B., Siepmann N., et al. Gastric inhibitory polypeptide (GIP) dose-dependently stimulates glucagon secretion in healthy human subjects at euglycemia. Diabetologia 46 (2003) 798-801
-
(2003)
Diabetologia
, vol.46
, pp. 798-801
-
-
Meier, J.J.1
Gallwitz, B.2
Siepmann, N.3
-
14
-
-
0027248866
-
Normalization of fasting hyperglycemia by exogenous glucagon-like peptide I (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients
-
Nauck M.A., Kleine N., Ørskov C., et al. Normalization of fasting hyperglycemia by exogenous glucagon-like peptide I (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients. Diabetologia 36 (1993) 741-744
-
(1993)
Diabetologia
, vol.36
, pp. 741-744
-
-
Nauck, M.A.1
Kleine, N.2
Ørskov, C.3
-
15
-
-
0029829821
-
Vagal hepatopancreatic reflex effect evoked by intraportal appearance of tGLP-I
-
Nakabayashi H., Nishizawa M., Nakagawa A., et al. Vagal hepatopancreatic reflex effect evoked by intraportal appearance of tGLP-I. American Journal of Physiology 271 (1996) E808-E813
-
(1996)
American Journal of Physiology
, vol.271
-
-
Nakabayashi, H.1
Nishizawa, M.2
Nakagawa, A.3
-
16
-
-
0033696456
-
Portal GLP-I administration in rats augments the insulin response to glucose via neuronal mechanisms
-
Balkan B., and Liu X. Portal GLP-I administration in rats augments the insulin response to glucose via neuronal mechanisms. American Journal of Physiology 279 (2000) R1449-R1454
-
(2000)
American Journal of Physiology
, vol.279
-
-
Balkan, B.1
Liu, X.2
-
17
-
-
0942287326
-
Sensory nerves contribute to insulin secretion by glucagon-like peptide-I in mice
-
Ahrén B. Sensory nerves contribute to insulin secretion by glucagon-like peptide-I in mice. American Journal of Physiology 286 (2004) R269-R272
-
(2004)
American Journal of Physiology
, vol.286
-
-
Ahrén, B.1
-
18
-
-
1442311383
-
Effects of glucagon-like peptide-I in patients with myocardial infarction and left ventricular dysfunction after successful reperfusion
-
Nikolaidis L.A., Mankad S., Sokos G.G., et al. Effects of glucagon-like peptide-I in patients with myocardial infarction and left ventricular dysfunction after successful reperfusion. Circulation 109 (2004) 962-965
-
(2004)
Circulation
, vol.109
, pp. 962-965
-
-
Nikolaidis, L.A.1
Mankad, S.2
Sokos, G.G.3
-
19
-
-
8544258807
-
Effects of glucagon-like peptide-I on endothelial function in type-2 diabetes patients with stable coronary artery disease
-
Nyström T., Gutniak M., Zhang Q., et al. Effects of glucagon-like peptide-I on endothelial function in type-2 diabetes patients with stable coronary artery disease. American Journal of Physiology 287 (2004) E1209-E1215
-
(2004)
American Journal of Physiology
, vol.287
-
-
Nyström, T.1
Gutniak, M.2
Zhang, Q.3
-
20
-
-
0026596851
-
Antidiabetic effect of glucagon-like peptide-I (7-36) amide in normal subjects and patients with diabetes mellitus
-
Gutniak M., Ørskov C., Holst J.J., et al. Antidiabetic effect of glucagon-like peptide-I (7-36) amide in normal subjects and patients with diabetes mellitus. The New England Journal of Medicine 326 (1992) 1316-1322
-
(1992)
The New England Journal of Medicine
, vol.326
, pp. 1316-1322
-
-
Gutniak, M.1
Ørskov, C.2
Holst, J.J.3
-
21
-
-
0029907680
-
Effects of subcutaneous glucagon-like peptide I (GLP-I [7-36 amide]) in patients with NIDDM
-
Nauck M.A., Wollschlager D., Werner J., et al. Effects of subcutaneous glucagon-like peptide I (GLP-I [7-36 amide]) in patients with NIDDM. Diabetologia 39 (1996) 1546-1553
-
(1996)
Diabetologia
, vol.39
, pp. 1546-1553
-
-
Nauck, M.A.1
Wollschlager, D.2
Werner, J.3
-
22
-
-
0037045845
-
Effect of 6-week course of glucagon-like peptide I on glycaemic control, insulin sensitivity, and β-cell function in type-2 diabetes: a parallel-group study
-
Zander M., Madsbad S., Madsen J.L., et al. Effect of 6-week course of glucagon-like peptide I on glycaemic control, insulin sensitivity, and β-cell function in type-2 diabetes: a parallel-group study. Lancet 359 (2002) 824-830
-
(2002)
Lancet
, vol.359
, pp. 824-830
-
-
Zander, M.1
Madsbad, S.2
Madsen, J.L.3
-
23
-
-
16244385334
-
Exenatide: a novel treatment of type-2 diabetes
-
Ahrén B. Exenatide: a novel treatment of type-2 diabetes. Therapy 2 (2005) 207-222
-
(2005)
Therapy
, vol.2
, pp. 207-222
-
-
Ahrén, B.1
-
24
-
-
33745771673
-
Biologic actions and therapeutical potential of the proglucagon-derived peptides
-
Drucker D.J. Biologic actions and therapeutical potential of the proglucagon-derived peptides. Nature Clinical Practice 1 (2005) 22-31
-
(2005)
Nature Clinical Practice
, vol.1
, pp. 22-31
-
-
Drucker, D.J.1
-
25
-
-
31844443202
-
Glucagon-like ptpide-I: from extract to agent. The Claude Bernard Lecture, 2005
-
Holst J.J. Glucagon-like ptpide-I: from extract to agent. The Claude Bernard Lecture, 2005. Diabetologia 49 (2006) 253-260
-
(2006)
Diabetologia
, vol.49
, pp. 253-260
-
-
Holst, J.J.1
-
26
-
-
27744605795
-
Inhibition of dipeptidyl peptidase-4 (DPP-4) -a novel approach to treat type-2 diabetes
-
Ahrén B. Inhibition of dipeptidyl peptidase-4 (DPP-4) -a novel approach to treat type-2 diabetes. Current Enzyme Inhibition 1 (2005) 65-73
-
(2005)
Current Enzyme Inhibition
, vol.1
, pp. 65-73
-
-
Ahrén, B.1
-
27
-
-
33846006173
-
The incretin system: glucagon-like peptide-I receptor agonists and dipeptidyl peptidase-4 inhibitors in type-2 diabetes
-
Drucker D.J., and Nauck M.A. The incretin system: glucagon-like peptide-I receptor agonists and dipeptidyl peptidase-4 inhibitors in type-2 diabetes. Lancet 368 (2006) 1696-1705
-
(2006)
Lancet
, vol.368
, pp. 1696-1705
-
-
Drucker, D.J.1
Nauck, M.A.2
-
28
-
-
33749834648
-
DPP-4 inhibitors and their potential role in the management of type-2 diabetes
-
Barnett A. DPP-4 inhibitors and their potential role in the management of type-2 diabetes. International Journal of Clinical Practice 60 (2006) 1454-1470
-
(2006)
International Journal of Clinical Practice
, vol.60
, pp. 1454-1470
-
-
Barnett, A.1
-
30
-
-
0033619675
-
Dipeptidyl-peptidase IV (CD26) -role in the inactivation of regulatory peptides
-
Mentlein R. Dipeptidyl-peptidase IV (CD26) -role in the inactivation of regulatory peptides. Regulatory Peptides 85 (1999) 9-24
-
(1999)
Regulatory Peptides
, vol.85
, pp. 9-24
-
-
Mentlein, R.1
-
31
-
-
0037787851
-
Dipeptidyl-peptidase IV from bench to bedside: an update on structural properties, functions, and clinical aspects of the enzyme DPP IV
-
Lambeir A.M., Durinx C., Sharpe S., et al. Dipeptidyl-peptidase IV from bench to bedside: an update on structural properties, functions, and clinical aspects of the enzyme DPP IV. Critical Reviews In Clinical Laboratory Sciences 40 (2003) 209-294
-
(2003)
Critical Reviews In Clinical Laboratory Sciences
, vol.40
, pp. 209-294
-
-
Lambeir, A.M.1
Durinx, C.2
Sharpe, S.3
-
33
-
-
0031690479
-
Inhibition of the activity of dipeptidyl-peptidase IV as a treatment for type-2 diabetes
-
Holst J.J., and Deacon C.F. Inhibition of the activity of dipeptidyl-peptidase IV as a treatment for type-2 diabetes. Diabetes 47 (1998) 1663-1670
-
(1998)
Diabetes
, vol.47
, pp. 1663-1670
-
-
Holst, J.J.1
Deacon, C.F.2
-
34
-
-
0031916924
-
Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect of glucagon-like peptide-I in anesthetized pigs
-
Deacon C.F., Hughes T.E., and Holst J.J. Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect of glucagon-like peptide-I in anesthetized pigs. Diabetes 47 (1998) 764-769
-
(1998)
Diabetes
, vol.47
, pp. 764-769
-
-
Deacon, C.F.1
Hughes, T.E.2
Holst, J.J.3
-
35
-
-
0034666562
-
Improved glucose tolerance and insulin secretion by inhibition of dipeptidyl peptidase IV in mice
-
Ahrén B., Holst J.J., Martensson H., et al. Improved glucose tolerance and insulin secretion by inhibition of dipeptidyl peptidase IV in mice. European Journal of Endocrinology 404 (2000) 239-245
-
(2000)
European Journal of Endocrinology
, vol.404
, pp. 239-245
-
-
Ahrén, B.1
Holst, J.J.2
Martensson, H.3
-
36
-
-
2442482515
-
Inhibition of dipeptidyl peptidase-4 reduces glycemia, sustains insulin levels and reduces glucagon levels in type-2 diabetes
-
Ahrén B., Landin-Olsson M., Jansson P.A., et al. Inhibition of dipeptidyl peptidase-4 reduces glycemia, sustains insulin levels and reduces glucagon levels in type-2 diabetes. The Journal of Clinical Endocrinology and Metabolism 89 (2004) 2078-2084
-
(2004)
The Journal of Clinical Endocrinology and Metabolism
, vol.89
, pp. 2078-2084
-
-
Ahrén, B.1
Landin-Olsson, M.2
Jansson, P.A.3
-
37
-
-
0037777695
-
1 [[ (3-hydroxy-1-adamantyl) amino-]acetyl]-2-cyano-(s) -pyr-rolidine: a potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitor with antihyperglycemic properties
-
Villhauer E.B., Brinkman J.A., Naderi G.B., et al. 1 [[ (3-hydroxy-1-adamantyl) amino-]acetyl]-2-cyano-(s) -pyr-rolidine: a potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitor with antihyperglycemic properties. Journal of Medicinal Chemistry 46 (2003) 2774-2789
-
(2003)
Journal of Medicinal Chemistry
, vol.46
, pp. 2774-2789
-
-
Villhauer, E.B.1
Brinkman, J.A.2
Naderi, G.B.3
-
38
-
-
19944427998
-
(2R) -4-oxo-4-[3-(trifluoromethyl) -5,6-dihydro[1,2,4]triazol[4,3,a]pyra-zin-7 (8H) -yl]-l-(2,4,5-trifluorophenyl) butan-2-amine: a potent, orally active dipeptidyl peptidase IV inhibitor for the treatment of type-2 diabetes
-
Kim D., Wang L., Beconi M., et al. (2R) -4-oxo-4-[3-(trifluoromethyl) -5,6-dihydro[1,2,4]triazol[4,3,a]pyra-zin-7 (8H) -yl]-l-(2,4,5-trifluorophenyl) butan-2-amine: a potent, orally active dipeptidyl peptidase IV inhibitor for the treatment of type-2 diabetes. Journal of Medicinal Chemistry 48 (2005) 141-151
-
(2005)
Journal of Medicinal Chemistry
, vol.48
, pp. 141-151
-
-
Kim, D.1
Wang, L.2
Beconi, M.3
-
39
-
-
33749851508
-
Pharmacokinetics and pharmacodynamics of the DPP-4 inhibitor, LAF237, in patients with type-2 diabetes
-
He Y.L., Balch A., and Campestrini J. Pharmacokinetics and pharmacodynamics of the DPP-4 inhibitor, LAF237, in patients with type-2 diabetes. Clinical Pharmacology and Therapy 56 (2005) 19
-
(2005)
Clinical Pharmacology and Therapy
, vol.56
, pp. 19
-
-
He, Y.L.1
Balch, A.2
Campestrini, J.3
-
40
-
-
28844482322
-
Pharmacokinetics and pharmacodynamics of sitagliptin, an inhibitor of dipeptidyl peptidase IV, in healthy subjects: results from two randomized, double-blind, placebocontrolled studies with single oral doses
-
Herman G.A., Stevens C., Van Dyck K., et al. Pharmacokinetics and pharmacodynamics of sitagliptin, an inhibitor of dipeptidyl peptidase IV, in healthy subjects: results from two randomized, double-blind, placebocontrolled studies with single oral doses. Clinical Pharmacology and Therapy 78 (2005) 675-688
-
(2005)
Clinical Pharmacology and Therapy
, vol.78
, pp. 675-688
-
-
Herman, G.A.1
Stevens, C.2
Van Dyck, K.3
-
41
-
-
33749838375
-
Effect of renal insufficiency on the pharmacokinetics of MK-0431 (sitagliptin), a selective dipeptidyl-peptidase-IV (DPP-IV) inhibitor
-
[abstr 46]
-
[abstr 46]. Bergman A.J., Coyte J., and Yi B. Effect of renal insufficiency on the pharmacokinetics of MK-0431 (sitagliptin), a selective dipeptidyl-peptidase-IV (DPP-IV) inhibitor. Clinical Pharmacology and Therapy 38 (2006)
-
(2006)
Clinical Pharmacology and Therapy
, vol.38
-
-
Bergman, A.J.1
Coyte, J.2
Yi, B.3
-
42
-
-
33749871472
-
Effect of single oral doses of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on incretin and plasma glucose levels after an oral glucose tolerance test in patients with type-2 diabetes
-
Herman G.A., Bergman A., Stevens C., et al. Effect of single oral doses of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on incretin and plasma glucose levels after an oral glucose tolerance test in patients with type-2 diabetes. The Journal of Clinical Endocrinology and Metabolism 91 (2006) 4612-4619
-
(2006)
The Journal of Clinical Endocrinology and Metabolism
, vol.91
, pp. 4612-4619
-
-
Herman, G.A.1
Bergman, A.2
Stevens, C.3
-
44
-
-
8844253433
-
Acute DPP IV inhibition minimizes glucose and insulin response to a glucose challenge in a diabetic mouse
-
Mika M., Stashko M., Lubben T., et al. Acute DPP IV inhibition minimizes glucose and insulin response to a glucose challenge in a diabetic mouse. Diabetes 52 Suppl 1 (2003) A350
-
(2003)
Diabetes
, vol.52
, Issue.SUPPL. 1
-
-
Mika, M.1
Stashko, M.2
Lubben, T.3
-
45
-
-
3543009434
-
The high-fat fed mouse: a model for studying mechanisms and treatment of impaired glucose tolerance and type-2 diabetes
-
Sörhede Winzell M., and Ahrén B. The high-fat fed mouse: a model for studying mechanisms and treatment of impaired glucose tolerance and type-2 diabetes. Diabetes 53 Suppl 3 (2003) S215-S219
-
(2003)
Diabetes
, vol.53
, Issue.SUPPL. 3
-
-
Sörhede Winzell, M.1
Ahrén, B.2
-
46
-
-
33748331194
-
Chronic inhibition of dipeptidyl peptidase-4 with a sitagliptin analog preserves pancreatic β-cell mass and function in a rodent model of type-2 diabetes
-
Mu J., Woods J., Zhou Y.P., et al. Chronic inhibition of dipeptidyl peptidase-4 with a sitagliptin analog preserves pancreatic β-cell mass and function in a rodent model of type-2 diabetes. Diabetes 55 (2006) 1695-1704
-
(2006)
Diabetes
, vol.55
, pp. 1695-1704
-
-
Mu, J.1
Woods, J.2
Zhou, Y.P.3
-
47
-
-
0036583164
-
Inhibition of dipeptidyl peptidase IV improves metabolic control over a 4 week study period in type-2 diabetes
-
Ahrén B., Simonsson E., Larsson H., et al. Inhibition of dipeptidyl peptidase IV improves metabolic control over a 4 week study period in type-2 diabetes. Diabetes Care 25 (2002) 869-875
-
(2002)
Diabetes Care
, vol.25
, pp. 869-875
-
-
Ahrén, B.1
Simonsson, E.2
Larsson, H.3
-
48
-
-
27744540889
-
Improved glucaemic control with dipeptidyl peptidase-4 inhibition in patients with type-2 diabetes: vildagliptin (LAF237) dose response
-
Ristic S., Byiers S., Foley J., et al. Improved glucaemic control with dipeptidyl peptidase-4 inhibition in patients with type-2 diabetes: vildagliptin (LAF237) dose response. Diabetes, Obesity & Metabolism 7 (2005) 692-698
-
(2005)
Diabetes, Obesity & Metabolism
, vol.7
, pp. 692-698
-
-
Ristic, S.1
Byiers, S.2
Foley, J.3
-
49
-
-
33745903093
-
Twelve-week monotherapy with the DPP-4 inhibitor vildagliptin improves glycémic control in subjects with type-2 diabetes
-
Pratley R.E., Jauffret-Kamel S., Galbreath E., et al. Twelve-week monotherapy with the DPP-4 inhibitor vildagliptin improves glycémic control in subjects with type-2 diabetes. Hormone and Metabolic Research 387 (2006) 423-438
-
(2006)
Hormone and Metabolic Research
, vol.387
, pp. 423-438
-
-
Pratley, R.E.1
Jauffret-Kamel, S.2
Galbreath, E.3
-
50
-
-
33846905487
-
Efficacy and tolerability of vildagliptin monotherapy in drugnaïve patients with type-2 diabetes
-
Pi-Sunyer F.X., Schweizer A., Mills D., et al. Efficacy and tolerability of vildagliptin monotherapy in drugnaïve patients with type-2 diabetes. Diabetes Research and Clinical Practice 76 (2007) 132-138
-
(2007)
Diabetes Research and Clinical Practice
, vol.76
, pp. 132-138
-
-
Pi-Sunyer, F.X.1
Schweizer, A.2
Mills, D.3
-
51
-
-
33846694046
-
Comparison of vildagliptin and rosiglitazone monotherapy in patients with type-2 diabetes: a 24-week, double-blind, randomized trial
-
Rosenstock J., Baron M.A., Dejager S., et al. Comparison of vildagliptin and rosiglitazone monotherapy in patients with type-2 diabetes: a 24-week, double-blind, randomized trial. Diabetes Care 30 (2007) 217-223
-
(2007)
Diabetes Care
, vol.30
, pp. 217-223
-
-
Rosenstock, J.1
Baron, M.A.2
Dejager, S.3
-
52
-
-
60649093860
-
Comparison between vildagliptin and metformin to sustain reductions in HbA(Ic) over 1 year in drug-naïve patients with type 2 diabetes
-
in press
-
Couturier A, Foley JE, Dejager S. Comparison between vildagliptin and metformin to sustain reductions in HbA(Ic) over 1 year in drug-naïve patients with type 2 diabetes. Diabetic Medicine, in press.
-
Diabetic Medicine
-
-
Couturier, A.1
Foley, J.E.2
Dejager, S.3
-
53
-
-
33645037183
-
Effect of MK-0431, a dipeptidyl peptidase IV (DPP-IV) inhibitor, on glycemic control after 12 weeks in patients with type-2 diabetes
-
Hanefeld M., Herman G., Mickel C., et al. Effect of MK-0431, a dipeptidyl peptidase IV (DPP-IV) inhibitor, on glycemic control after 12 weeks in patients with type-2 diabetes. Diabetologia 49 Suppl 1 (2005) A287
-
(2005)
Diabetologia
, vol.49
, Issue.SUPPL. 1
-
-
Hanefeld, M.1
Herman, G.2
Mickel, C.3
-
54
-
-
33847024333
-
Efficacy and tolerability of the dipeptidyl peptidase-4 inhibitor sitagliptin as monotherapy over 12 weeks in patients with type-2 diabetes
-
Scott R., Wu L., Sanchez M., et al. Efficacy and tolerability of the dipeptidyl peptidase-4 inhibitor sitagliptin as monotherapy over 12 weeks in patients with type-2 diabetes. International Journal of Clinical Practice 61 (2007) 171-180
-
(2007)
International Journal of Clinical Practice
, vol.61
, pp. 171-180
-
-
Scott, R.1
Wu, L.2
Sanchez, M.3
-
55
-
-
33845489598
-
Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin as monotherapy in patients with type-2 diabetes mellitus
-
Raz I., Hanefeld M., Xu L., et al. Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin as monotherapy in patients with type-2 diabetes mellitus. Diabetologia 49 (2006) 2564-2571
-
(2006)
Diabetologia
, vol.49
, pp. 2564-2571
-
-
Raz, I.1
Hanefeld, M.2
Xu, L.3
-
56
-
-
33845472504
-
Effect of the dipeptidyl peptidase-4 inhibitor sitagliptin as monotherapy on glycemic control in patients with type-2 diabetes
-
Aschner P., Kipnes M.S., Lunceford J.K., et al. Effect of the dipeptidyl peptidase-4 inhibitor sitagliptin as monotherapy on glycemic control in patients with type-2 diabetes. Diabetes Care 29 (2006) 2632-2637
-
(2006)
Diabetes Care
, vol.29
, pp. 2632-2637
-
-
Aschner, P.1
Kipnes, M.S.2
Lunceford, J.K.3
-
57
-
-
9444285818
-
Twelve-and 52-week efficacy of the dipeptidyl peptidase IV inhibitor LAF237 in metformin-treated patients with type-2 diabetes
-
Ahrén B., Gomis R., Standl E., et al. Twelve-and 52-week efficacy of the dipeptidyl peptidase IV inhibitor LAF237 in metformin-treated patients with type-2 diabetes. Diabetes Care 27 (2004) 2874-2880
-
(2004)
Diabetes Care
, vol.27
, pp. 2874-2880
-
-
Ahrén, B.1
Gomis, R.2
Standl, E.3
-
58
-
-
34147093268
-
Effects of vildagliptin on glucose control over 24 weeks in patients with type-2 diabetes inadequately controlled with metformin
-
Bosi E., Camisaca R.P., Collober C., et al. Effects of vildagliptin on glucose control over 24 weeks in patients with type-2 diabetes inadequately controlled with metformin. Diabetes Care 30 (2007) 890-895
-
(2007)
Diabetes Care
, vol.30
, pp. 890-895
-
-
Bosi, E.1
Camisaca, R.P.2
Collober, C.3
-
59
-
-
33845476757
-
Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin added to ongoing metformin therapy in patients with type-2 diabetes inadequately controlled with metformin alone
-
Charbonnel B., Karasik A., Liu J., et al. Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin added to ongoing metformin therapy in patients with type-2 diabetes inadequately controlled with metformin alone. Diabetes Care 29 (2006) 2638-2643
-
(2006)
Diabetes Care
, vol.29
, pp. 2638-2643
-
-
Charbonnel, B.1
Karasik, A.2
Liu, J.3
-
60
-
-
33846817233
-
Efficacy and safety of the dipeptidyl peptidase-4 inhibitor, sitagliptin, compared with the sulfonylurea, glipizide, in patients with type 2 diabetes inadequately controlled on metformin alone: a randomized, double-blind, non-inferiority trial
-
Nauck M.A., Meininger G., Sheng D., et al. Efficacy and safety of the dipeptidyl peptidase-4 inhibitor, sitagliptin, compared with the sulfonylurea, glipizide, in patients with type 2 diabetes inadequately controlled on metformin alone: a randomized, double-blind, non-inferiority trial. Diabetes, Obesity & Metabolism 9 (2007) 194-205
-
(2007)
Diabetes, Obesity & Metabolism
, vol.9
, pp. 194-205
-
-
Nauck, M.A.1
Meininger, G.2
Sheng, D.3
-
61
-
-
33846828660
-
Vildagliptin in combination with pioglitazeone improves glycaemic control in patients with type-2 diabetes failing thiazolidinedione monotherapy: a randomized, placebo-controlled study
-
Garber A., Schweizer A., Baron M.A., et al. Vildagliptin in combination with pioglitazeone improves glycaemic control in patients with type-2 diabetes failing thiazolidinedione monotherapy: a randomized, placebo-controlled study. Diabetes, Obesity & Metabolism 9 (2007) 166-174
-
(2007)
Diabetes, Obesity & Metabolism
, vol.9
, pp. 166-174
-
-
Garber, A.1
Schweizer, A.2
Baron, M.A.3
-
62
-
-
33751557143
-
Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin added to ongoing pioglitazone therapy in patients with type-2 diabetes: a 24-week, multicenter, randomized, double-blind, placebo-controlled, parallel-group study
-
Rosenstock J., Brazg R.G., Andryuk P.J., et al. Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin added to ongoing pioglitazone therapy in patients with type-2 diabetes: a 24-week, multicenter, randomized, double-blind, placebo-controlled, parallel-group study. Clinical Therapeutics 28 (2006) 1556-1568
-
(2006)
Clinical Therapeutics
, vol.28
, pp. 1556-1568
-
-
Rosenstock, J.1
Brazg, R.G.2
Andryuk, P.J.3
-
63
-
-
34247874561
-
Addition of vildagliptin to insulin improves glycaemic control in type 2 diabetes
-
Fonseca V., Schweizer A., Albrecht D., et al. Addition of vildagliptin to insulin improves glycaemic control in type 2 diabetes. Diabetologia 50 (2007) 1148-1155
-
(2007)
Diabetologia
, vol.50
, pp. 1148-1155
-
-
Fonseca, V.1
Schweizer, A.2
Albrecht, D.3
-
65
-
-
25844459084
-
Dipeptidyl peptidase IV inhibition for the treatment of type-2 diabetes: potential importance of selectivity over dipeptidyl peptidases 8 and 9
-
Lankas G.R., Leiting B., Roy R.S., et al. Dipeptidyl peptidase IV inhibition for the treatment of type-2 diabetes: potential importance of selectivity over dipeptidyl peptidases 8 and 9. Diabetes 54 (2005) 2988-2994
-
(2005)
Diabetes
, vol.54
, pp. 2988-2994
-
-
Lankas, G.R.1
Leiting, B.2
Roy, R.S.3
-
66
-
-
23844463766
-
Vildagliptin, a dipeptidyl peptidase-IV inhibitor, improves model-assessed beta-cell function in patients with type-2 diabetes
-
Mari A., Sallas W.M., He Y.L., et al. Vildagliptin, a dipeptidyl peptidase-IV inhibitor, improves model-assessed beta-cell function in patients with type-2 diabetes. The Journal of Clinical Endocrinology and Metabolic 90 (2005) 4888-4894
-
(2005)
The Journal of Clinical Endocrinology and Metabolic
, vol.90
, pp. 4888-4894
-
-
Mari, A.1
Sallas, W.M.2
He, Y.L.3
-
67
-
-
23044487247
-
Improved meal-related beta-cell function and insulin sensitivity by the dipeptidyl peptidase-IV inhibitor vildagliptin in metformin-treated patients with type-2 diabetes over 1 year
-
Ahrén B., Pacini G., Foley J.E., et al. Improved meal-related beta-cell function and insulin sensitivity by the dipeptidyl peptidase-IV inhibitor vildagliptin in metformin-treated patients with type-2 diabetes over 1 year. Diabetes Care 28 (2005) 1936-1940
-
(2005)
Diabetes Care
, vol.28
, pp. 1936-1940
-
-
Ahrén, B.1
Pacini, G.2
Foley, J.E.3
-
68
-
-
34147189738
-
The dipeptidyl peptidase IV inhibitor vildagliptin suppresses endogenous glucose production and enhances islet function after single dose administration in type 2 diabetic patients
-
Balas B., Baig M.R., Watson C., et al. The dipeptidyl peptidase IV inhibitor vildagliptin suppresses endogenous glucose production and enhances islet function after single dose administration in type 2 diabetic patients. The Journal of Clinical Endocrinology and Metabolism 92 (2007) 1249-1255
-
(2007)
The Journal of Clinical Endocrinology and Metabolism
, vol.92
, pp. 1249-1255
-
-
Balas, B.1
Baig, M.R.2
Watson, C.3
-
69
-
-
0036959991
-
Effects of glucagon-like peptide I on counterregulatory hormone responses, cognitive functions, and insulin secretion during hyperinsulinemic, stepped hypoglycemie clamp experiments in healthy volunteers
-
Nauck M.A., Heimesaat M.M., Behle K., et al. Effects of glucagon-like peptide I on counterregulatory hormone responses, cognitive functions, and insulin secretion during hyperinsulinemic, stepped hypoglycemie clamp experiments in healthy volunteers. The Journal of Clinical Endocrinology and Metabolism 87 (2002) 1239-1246
-
(2002)
The Journal of Clinical Endocrinology and Metabolism
, vol.87
, pp. 1239-1246
-
-
Nauck, M.A.1
Heimesaat, M.M.2
Behle, K.3
-
71
-
-
0037342614
-
Dipeptidyl peptidase IV inhibitor treatment stimulates beta-cell survival and islet neogenesis in streptozotocin-induced diabetic rats
-
Pospisilik J.A., Martin J., Doty T., et al. Dipeptidyl peptidase IV inhibitor treatment stimulates beta-cell survival and islet neogenesis in streptozotocin-induced diabetic rats. Diabetes 52 (2003) 741-750
-
(2003)
Diabetes
, vol.52
, pp. 741-750
-
-
Pospisilik, J.A.1
Martin, J.2
Doty, T.3
-
72
-
-
34147172248
-
The DPP-4 inhibitor vildagliptin increases β-cell mass in rodents
-
Duttaroy A., Voelker F., Zhang X., et al. The DPP-4 inhibitor vildagliptin increases β-cell mass in rodents. Diabetologia 48 Suppl 1 (2005) A178
-
(2005)
Diabetologia
, vol.48
, Issue.SUPPL. 1
-
-
Duttaroy, A.1
Voelker, F.2
Zhang, X.3
-
73
-
-
33746690405
-
Vildagliptin therapy reduces postprandial intestinal triglyceride-rich lipoprotein particles in patients with type-2 diabetes
-
Matikainen N., Mänttäri S., Schweizer A., et al. Vildagliptin therapy reduces postprandial intestinal triglyceride-rich lipoprotein particles in patients with type-2 diabetes. Diabetologia 49 (2006) 2049-2057
-
(2006)
Diabetologia
, vol.49
, pp. 2049-2057
-
-
Matikainen, N.1
Mänttäri, S.2
Schweizer, A.3
-
74
-
-
0038497464
-
Synthetic exendin-4 (exenatide) significantly reduces postprandial and fasting plasma glucose in subjects with type-2 diabetes
-
Kolterman O.G., Buse J.B., Fineman M.S., et al. Synthetic exendin-4 (exenatide) significantly reduces postprandial and fasting plasma glucose in subjects with type-2 diabetes. The Journal of Clinical Endocrinology and Metabolism 88 (2003) 3082-3089
-
(2003)
The Journal of Clinical Endocrinology and Metabolism
, vol.88
, pp. 3082-3089
-
-
Kolterman, O.G.1
Buse, J.B.2
Fineman, M.S.3
-
75
-
-
34248169217
-
Effects of dipeptidyl peptidase 4 inhibition on gastrointestinal function, meal appearance and glucose metabolism in type-2 diabetes
-
Vella A., Bock G., Giesler P.D., et al. Effects of dipeptidyl peptidase 4 inhibition on gastrointestinal function, meal appearance and glucose metabolism in type-2 diabetes. Diabetes 56 (2007) 1475-1480
-
(2007)
Diabetes
, vol.56
, pp. 1475-1480
-
-
Vella, A.1
Bock, G.2
Giesler, P.D.3
|