Association of the single-nucleotide polymorphism and haplotype of the P-selectin gene with ischemic stroke

Journal of Thrombosis and Thrombolysis

Volumn 27, Issue 1, 2009, Pages 75-81

  Wei, Ye Sheng ^a   Lan, Yan ^a   Huang, Rui Ya ^a   Liu, Yun Guang ^a   Tang, Ren Guang ^a   Xu, Qun Qin ^a   Meng, Lan Qing ^a  

^a YOUJIANG MEDICAL COLLEGE FOR NATIONALITIES   (China)

Author keywords

Gene; Haplotype; Ischemic stroke; P selectin; Polymorphism

Indexed keywords

ADENOSINE; CYTOSINE; GUANOSINE; PADGEM PROTEIN; PROLINE; THREONINE; THYMIDINE;

ADULT; AGED; ARTICLE; CEREBROVASCULAR ACCIDENT; CHINESE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DISEASE COURSE; DNA SEQUENCE; FEMALE; GENE FREQUENCY; GENE INTERACTION; GENETIC ASSOCIATION; GENETIC RISK; GENOTYPE; HAPLOTYPE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEOTIDE SEQUENCE; PATHOGENESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; AGED, 80 AND OVER; ALLELES; BRAIN ISCHEMIA; CHINA; COMORBIDITY; FEMALE; GENE FREQUENCY; GENOTYPE; HAPLOTYPES; HUMANS; HYPERLIPIDEMIAS; HYPERTENSION; INTRACRANIAL ARTERIOSCLEROSIS; MALE; MIDDLE AGED; OBESITY; P-SELECTIN; POLYMORPHISM, SINGLE NUCLEOTIDE; RETROSPECTIVE STUDIES; RISK FACTORS; YOUNG ADULT;

EID: 60649107919     PISSN: 09295305     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11239-007-0168-8     Document Type: Article

References (38)

1. Libby P (2002) Inflammation in atherosclerosis. Nature 420:868-874
2. Williams KJ, Tabas I (2002) Atherosclerosis and inflammation. Science 297:521-522
3. Ross R (1999) Atherosclerosis: An inflammatory disease. New Engl J Med 340:115-126
4. Albelda SM, Smith CW, Ward PA (1994) Adhesion molecules and inflammatory injury. FASEB J 8:504-512
5. Huo Y, Ley K (2001) Adhesion molecules and atherogenesis. Acta Physiol Scand 173:35-43
6. Elangbam CS, Qualls CW Jr, Dahlgren RR (1997) Cell adhesion molecules-update. Vet Pathol 34:61-73
7. McEver RP (1990) Properties of GMP-140, an inducible granule membrane protein of platelets and endothelium. Blood Cells 16:73-80
8. Dong ZM, Chapman SM, Brown AA et al (1998) The combined role of P- and E-selectins in atherosclerosis. J Clin Invest 102:145-152
9. Nadar SK, Lip GY, Blann AD (2004) Platelet morphology, soluble P selectin and platelet P-selectin in acute ischaemic stroke. The West Birmingham Stroke Project. Thromb Haemost 92:1342-1348
10. Conway DS, Pearce LA, Chin BS, Hart RG, Lip GY (2002) Plasma von Willebrand factor and soluble p-selectin as indices of endothelial damage and platelet activation in 1321 patients with nonvalvular atrial fibrillation: Relationship to stroke risk factors. Circulation 106:1962-1967
11. Ridker PM, Buring JE, Rifai N (2001) Soluble P-selectin and the risk of future cardiovascular events. Circulation 103:491-495
12. Herrmann SM, Ricard S, Nicaud V, Mallet C, Evans A, Ruidavets JB, Arveiler D, Luc G, Cambien F (1998) The P-selectin gene is highly polymorphic: Reduced frequency of the Pro715 allele carriers in patients with myocardial infarction. Hum Mol Genet 7:1277-1284
13. Miller MA, Kerry SM, Dong Y, Strazzullo P, Cappuccio FP (2004) Association between the Thr715Pro P-selectin gene polymorphism and soluble P-selectin levels in a multiethnic population in South London. Thromb Haemost 92:1060-1065
14. Volcik KA, Ballantyne CM, Coresh J, Folsom AR, Wu KK, Boerwinkle E (2006) P-selectin Thr715Pro polymorphism predicts P-selectin levels but not risk of incident coronary heart disease or ischemic stroke in a cohort of 14595 participants: The Atherosclerosis Risk in Communities Study. Atherosclerosis 186:74-79
15. Volcik KA, Ballantyne CM, Coresh J, Folsom AR, Boerwinkle E. Specific P-selectin and P-selectin glycoprotein ligand-1 genotypes/haplotypes are associated with risk of incident CHD and ischemic stroke: The Atherosclerosis Risk in Communities (ARIC) Study. Atherosclerosis. 2007 Apr 7; [Epub ahead of print]
16. Ferrari J, Rieger S, Endler G, Greisenegger S, Funk M, Scholze T, Lang W, Lalouschek W, Mannhalter C (2007) The Thr715Pro polymorphism of the P-selectin gene is not associated with ischemic stroke risk. Stroke 38:395-397
17. Adams HP Jr, Bendixen BH, Kappelle LJ, Biller J, Love BB, Gordon DL, Marsh EE 3rd (1993) Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in acute stroke treatment. Stroke 24:35-41
18. John SW, Weitzner G, Rozen R, Scriver CR (1991) A rapid procedure for extracting genomic DNA from leukocytes. Nucleic Acids Res 19:408
19. Carter AM, Anagnostopoulou K, Mansfield MW, Grant PJ (2003) Soluble P-selectin levels. P-selectin polymorphisms and cardiovascular disease. J Thromb Haemost 1:1718-1723
20. Shi YY, He L (2005) SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci. Cell Res 15:97-98
21. Stephens M, Smith MJ, Donnelly P (2001) A new statistical method for haplotype reconstruction from population data. Am J Hum Genet 68:978-989
22. Tregouet DA, Barbaux S, Escolano S, et al (2002) Specific haplotypes of the P-selectin gene are associated with myocardial infarction. Hum Mol Genet 11:2015-2023
23. Bugert P, Vosberg M, Entelmann M, Jahn J, Katus HA, Kluter H (2004) Polymorphisms in the P-selectin (CD62P) and P-selectin glycoprotein ligand-1 (PSGL-1) genes and coronary heart disease. Clin Chem Lab Med 42:997-1004
24. Davis NE (2005) Atherosclerosis-an inflammatory process. J Insur Med 37:72-75
25. Blankenberg S, Barbaux S, Tiret L (2003) Adhesion molecules and atherosclerosis. Atherosclerosis 170:191-203
26. Elkind MS (2006) Inflammation, atherosclerosis, and stroke. Neurologist 12:140-148
27. Johnson-Tidey RR, McGregor JL, Taylor PR, Poston RN (1994) Increase in the adhesion molecule P-selectin in endothelium overlying atherosclerotic plaques. Coexpression with intercellular adhesion molecule-1. Am J Pathol 144:952-961
28. Johnson R, Chapman S, Dong Z, Ordovas J, Mayadas T, Herz J, Hynes R, Schaefer E, Wagner D (1997) Absence of P-selectin delays fatty streak formation in mice. J Clin Invest 99:1037-1043
29. Nageh M, Sandberg E, Marotti K, Lin A, Melchior E, Bullard D, Beaudet A (1997) Deficiency of inflammatory cell adhesion molecules protects against atherosclerosis in mice. Arterioscler Thromb Vasc Biol 17:1517-1520
30. Collins R, Velji R, Guevara N, Hicks M, Chan L, Beaudet A (2000) P-selectin or intercellular adhesion molecule (ICAM)-1 deficiency substantially protects against atherosclerosis in apolipoprotein E-deficient mice. J Exp Med 191:189-194
31. Dong Z, Brown A, Wagner D (2000) Prominent role of P-selectin in the development of advanced atherosclerosis in ApoE-deficient mice. Circulation 101:2290-2295
32. Ramos C, Huo Y, Jung U, Ghosh S, Manka D, Sarembock I, Ley K (1999) Direct demonstration of P-selectin- and VCAM-1-dependent mononuclear cell rolling in early atherosclerotic lesions of apolipoprotein E-deficient mice. Circ Res 84:1237-1244
33. Bienvenu J, Tanguay J, Théorêt J, Kumar A, Schaub R, Merhi Y (2001) Recombinant soluble P-selectin glycoprotein ligand-1-Ig reduces restenosis through inhibition of platelet-neutrophil adhesion after double angioplasty in swine. Circulation 103:1128-1134
34. Merten M, Thiagarajan P (2000) P-selectin expression on platelets determines size and stability of platelet aggregates. Circulation 102:1931-1936
35. Andre P, Hartwell D, Hrachovinova I, Saffaripour S, Wagner D (2000) Procoagulant state resulting from high levels of soluble P-selectin in blood. Proc Natl Acad Sci USA 97:13835-13840
36. Frijns CJ, Kappelle LJ, van Gijn J, Nieuwenhuis HK, Sixma JJ, Fijnheer R (1997) Soluble adhesion molecules reflect endothelial cell activation in ischemic stroke and in carotid atherosclerosis. Stroke 28:2214-2218
37. Kee F, Morrison C, Evans AE, McCrum E, McMaster D, Dallongeville J, Nicaud V, Poirier O, Cambien F (2000) Polymorphisms of the P-selectin gene and risk of myocardial infarction in men and women in the ECTIM extension study. Etude cas-temoin de l'infarctus myocarde Heart 84:548-552
38. Barbaux SC, Blankenberg S, Rupprecht HJ, Francomme C, Bickel C, Hafner G, Nicaud V, Meyer J, Cambien F, Tiret L (2001) Association between P-selectin gene polymorphisms and soluble P-selectin levels and their relation to coronary artery disease. Arterioscler Thromb Vasc Biol 21:1668-1673