Induction of apoptosis of detached oral squamous cell carcinoma cells by safingol. Possible role of Bim, focal adhesion kinase and endonuclease G

Apoptosis

Volumn 14, Issue 3, 2009, Pages 287-297

  Noda, Takayuki ^a   Iwai, Soichi ^a   Hamada, Masakazu ^a   Fujita, Yusei ^a   Yura, Yoshiaki ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

Anoikis; Bcl 2 family protein; Endonuclease G; Focal adhesion kinase; Oral squamous cell carcinoma; Protein kinase C inhibitor

Indexed keywords

AGAROSE; BIM PROTEIN; CELL DNA; ENDONUCLEASE G; FOCAL ADHESION KINASE; POLYMACON; PROTEIN BCL 2; PROTEIN BCL XL; SAFINGOL; SMALL INTERFERING RNA;

AGAR GEL ELECTROPHORESIS; ANOIKIS; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CARCINOMA CELL; CELL ADHESION; CELL CULTURE; CELL CYCLE G1 PHASE; CELL STRAIN CA9 22; CELL STRAIN HSC 3; CELL STRAIN SAS; CELL SURVIVAL; CELL SUSPENSION; CELL VIABILITY; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG DOSE INCREASE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; INCUBATION TIME; MONOLAYER CULTURE; MOUTH CARCINOMA; PRIORITY JOURNAL; PROTEIN FUNCTION; SQUAMOUS CELL CARCINOMA;

ANOIKIS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CARCINOMA, SQUAMOUS CELL; CASPASE 3; CELL CYCLE; CELL LINE, TUMOR; CELL SURVIVAL; CYTOCHROMES C; DNA FRAGMENTATION; ENDODEOXYRIBONUCLEASES; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HUMANS; MEMBRANE PROTEINS; MOUTH NEOPLASMS; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS; RNA, SMALL INTERFERING; SPHINGOSINE;

EID: 60649094611     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-009-0319-9     Document Type: Article

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