Synthesis of new 2-(5-substituted-3-phenyl-2-pyrazolinyl)-1,3-thiazolino[5,4-b]quinoxaline derivatives and evaluation of their antiamoebic activity

European Journal of Medicinal Chemistry

Volumn 44, Issue 3, 2009, Pages 1317-1325

  Budakoti, Asha ^a   Bhat, Abdul Roouf ^a   Azam, Amir ^a  

^a JAMIA MILLIA ISLAMIA CENTRAL UNIVERSITY   (India)

Author keywords

Antiamoebic activity; Chalcone; Pyrazolines; Quinoxaline; Thiocarbamoyl

Indexed keywords

1 PHENYL 3 (2,4,6 TRIMETHYLPHENYL)PROP 2 EN 1 ONE; 1,3 DIPHENYL PROP 2 EN 1 ONE; 2 (3,5 DIPHENYL 2 PYRAZOLINYL) 1,3 THIAZOLINO[5,4 B]QUINOXALINE; 2 (5 INDOL 3 YL 3 PHENYL 2 PYRAZOLINYL) 1,3 THIAZOLINO[5,4 B]QUINOXALINE; 2 [3 PHENYL 5 (2,4,6 TRIMETHYLPHENYL) 2 PYRAZOLINYL] 1,3 THIAZOLINO[5,4 B]QUINOXALINE; 2 [5 (2 CHLOROPHENYL) 3 PHENYL 2 PYRAZOLINYL] 1,3 THIAZOLINO[5,4 B]QUINOXALINE; 2 [5 (2 ETHYLPHENYL) 3 PHENYL 2 PYRAZOLINYL] 1,3 THIAZOLINO[5,4 B]QUINOXALINE; 2 [5 (2 METHYLETHYLPHENYL) 3 PHENYL 2 PYRAZOLINYL] 1,3 THIAZOLINO[5,4 B]QUINOXALINE; 2 [5 (2,3 DICHLOROPHENYL) 3 PHENYL 2 PYRAZOLINYL] 1,3 THIAZOLINO[5,4 B]QUINOXALINE; 2 [5 (4 METHYLPHENYL) 3 PHENYL 2 PYRAZOLINYL] 1,3 THIAZOLINO[5,4 B]QUINOXALINE; 3 (2 CHLOROPHENYL) 1 PHENYLPROP 2 EN 1 ONE; 3 (2 ETHYLPHENYL) 1 PHENYLPROP 2 EN 1 ONE; 3 (2 METHYLETHYLPHENYL) 1 PHENYLPROP 2 EN 1 ONE; 3 (3,4 DICHLOROPHENYL) 1 PHENYLPROP 2 EN 1 ONE; 3 (4 METHYLPHENYL) 1 PHENYLPROP 2 EN 1 ONE; 3 INDOL 3 YL 1 PHENYLPROP 2 EN 1 ONE; AMINO[3 PHENYL 5 (2,4,6 METHYLPHENYL)(2 PYRAZOLINYL)]METHANE 1 THIONE; AMINO[3,5 DIPHENYL(2 PYRAZOLINYL)]METHANE 1 THIONE; AMINO[5 (2 CHLOROPHENYL) 3 PHENYL(2 PYRAZOLINYL)]METHANE 1 THIONE; AMINO[5 (2 ETHYLPHENYL) 3 PHENYL(2 PYRAZOLINYL)]METHANE 1 THIONE; AMINO[5 (2,3 DICHLOROPHENYL) 3 PHENYL(2 PYRAZOLINYL)]METHANE 1 THIONE; AMINO[5 (4 METHYLPHENYL) 3 PHENYL(2 PYRAZOLINYL)]METHANE 1 THIONE; AMINO[5 [2 (METHYLETHYLPHENYL) 3 PHENYL(2 PYRAZOLINYL)]]METHANE 1 THIONE; AMINO[5 INDOL 3 YL 3 PHENYL(2 PYRAZOLINYL)]METHANE 1 THIONE; ANTIAMEBIC AGENT; CHALCONE DERIVATIVE; METRONIDAZOLE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENTAMOEBA HISTOLYTICA; EPITHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; INFRARED SPECTROSCOPY; KIDNEY CELL; MASS SPECTROMETRY; PROTON NUCLEAR MAGNETIC RESONANCE;

AMOEBA; ANIMALS; ANTIPROTOZOAL AGENTS; DRUG EVALUATION, PRECLINICAL; QUINOXALINES; SPECTRUM ANALYSIS;

EID: 60549115097     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.02.002     Document Type: Article

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