Lysophosphatidylcholine mediates melanocyte dendricity through PKCζ activation

Journal of Investigative Dermatology

Volumn 127, Issue 3, 2007, Pages 668-675

  Scott, Glynis A ^a   Arioka, Manubu ^b   Jacobs, Stacey E ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; GUANINE NUCLEOTIDE BINDING PROTEIN; HORMONE; LYSOPHOSPHATIDYLCHOLINE; LYSOPHOSPHOLIPID; PHOSPHOLIPASE A2; PROTEIN KINASE C; PROTEIN KINASE C ZETA; RAC PROTEIN; RHO FACTOR;

ARTICLE; CELL ACTIVATION; CELL FUNCTION; CONTROLLED STUDY; DENDRITE; DOWNSTREAM PROCESSING; HUMAN; HUMAN CELL; HUMAN TISSUE; INHIBITION KINETICS; MELANOCYTE; MUTANT; NEWBORN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION;

EID: 33847016103     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/sj.jid.5700567     Document Type: Article

References (47)

1. Aoki J, Taira A, Takanezawa Y, Kishi Y, Hama K, Kishimoto T et al. (2002) Serum lysophosphatidic acid is produced through diverse phospholipase pathways. J Biol Chem 277:48737-44
2. Bassa BV, Roh DD, Vaziri ND, Kirschenbaum MA, Kamanna VS (1999) Lysophosphatidylcholine activates mesangial cell PKC and MAP kinase by PLCgamma-1 and tyrosine kinase-Ras pathways. Am J Physiol 277:F328-37
3. Bezzine S, Koduri RS, Valentin E, Murakami M, Kudo I, Ghomashchi F et al. (2000) Exogenously added human group X secreted phospholipase A(2) but not the group IB, IIA, and V enzymes efficiently release arachidonic acid from adherent mammalian cells. J Biol Chem 275:3179-91
4. Brooks G, Wilson RE, Dooley TP, Goss MW, Hart IR (1991) Protein kinase C down-regulation, and not transient activation, correlates with melanocyte growth. Cancer Res 51:3281-8
5. Brown MD, Cornejo BJ, Kuhn TB, Bamburg JR (2000) Cdc42 stimulates neurite outgrowth and formation of growth cone filopodia and lamellipodia. J Neurobiol 43:352-64
6. Busca R, Bertolotto C, Abbe P, Englaro W, Ishizaki T, Narumiya S et al. (1998) Inhibition of Rho is required for cAMP-induced melanoma cell differentiation. Mol Biol Cell 9:1367-78
7. Chen HC, Bandyopadhyay G, Sajan MP, Kanoh Y, Standaert M, Farese RV Jr et al. (2002) Activation of the ERK pathway and atypical protein kinase C isoforms in exercise- and aminoimidazole-4-carboxamide-1-beta-D- riboside (AICAR)-stimulated glucose transport. J Biol Chem 277:23554-62
8. Coleman ES, Wooten MW (1994) Nerve growth factor-induced differentiation of PC12 cells employs the PMA-insensitive protein kinase C-zeta isoform. J Mol Neurosci 5:39-57
9. Cowan CL, Steffen RP (1995) Lysophosphatidylcholine inhibits relaxation of rabbit abdominal aorta mediated by endothelium-derived nitric oxide and endothelium-derived hyperpolarizing factor independent of protein kinase C activation. Arterioscler Thromb Vasc Biol 15:2290-7
10. Etienne-Manneville S, Hall A (2001) Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta. Cell 106:489-98
11. Gomez J, Martinez de Aragon A, Bonay P, Pitton C, Garcia A, Silva A et al. (1995) Physical association and functional relationship between protein kinase C zeta and the actin cytoskeleton. Eur J Immunol 25:2673-8
12. Hanasaki K, Ono T, Saiga A, Morioka Y, Ikeda M, Kawamoto K et al. (1999) Purified group X secretory phospholipase A(2) induced prominent release of arachidonic acid from human myeloid leukemia cells. J Biol Chem 274:34203-11
13. Hara M, Yaar M, Gilchrest BA (1995) Endothelin-1 of keratinocyte origin is a mediator of melanocyte dendricity. J Invest Dermatol 105:744-8
14. Hunt G, Todd C, Cresswell JE, Thody AJ (1994) Alpha-melanocyte stimulating hormone and its analogue Nle4DPhe7 alpha-MSH affect morphology, tyrosinase activity and melanogenesis in cultured human melanocytes. J Cell Sci 107(Part 1):205-11
15. Ikeno Y, Konno N, Cheon SH, Bolchi A, Ottonello S, Kitamoto K et al. (2005) Secretory phospholipases A2 induce neurite outgrowth in PC12 cells through lysophosphatidylcholine generation and activation of G2A receptor. J Biol Chem 280:28044-52
16. Izumi Y, Hirose T, Tamai Y, Hirai S, Nagashima Y, Fujimoto T et al. (1998) An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3. J Cell Biol 143:95-106
17. Kougias P, Chai H, Lin PH, Lumsden AB, Yao Q, Chen CJ (2005) Lysophosphatidylcholine and secretory phospholipase A(2) in vascular disease: mediators of endothelial dysfunction and atherosclerosis. Med Sci Monit 12:RA5-16
18. Kugiyama K, Ohgushi M, Sugiyama S, Murohara T, Fukunaga K, Miyamoto E et al. (1992) Lysophosphatidylcholine inhibits surface receptor-mediated intracellular signals in endothelial cells by a pathway involving protein kinase C activation. Circ Res 71:1422-8
19. Lin P, Ye RD (2003) The lysophospholipid receptor G2A activates a specific combination of G proteins and promotes apoptosis. J Biol Chem 278:14379-86
20. Liu LZ, Zhao HL, Zuo J, Ho SK, Chan JC, Meng Y et al. (2006) Protein kinase C{zeta} mediates insulin-induced glucose transport through actin remodeling in L6 muscle cells. Mol Biol Cell 17:2322-30
21. Lopez-Nicolas R, Lopez-Andreo MJ, Marin-Vicente C, Gomez-Fernandez JC, Corbalan-Garcia S (2006) Molecular mechanisms of PKCalpha localization and activation by arachidonic acid. The C2 domain also plays a role. J Mol Biol 357:1105-20
22. Mazereeuw-Hautier J, Gres S, Fanguin M, Cariven C, Fauvel J, Perret B et al. (2005) Production of lysophosphatidic acid in blister fluid: involvement of a lysophospholipase D activity. J Invest Dermatol 125:421-7
23. Mitchell FE, Marais RM, Parker PJ (1989) The phosphorylation of protein kinase C as a potential measure of activation. Biochem J 261:131-6
24. Murakami M, Kudo I (2001) Diversity and regulatory functions of mammalian secretory phospholipase A2s. Adv Immunol 77:163-94
25. Nakashima S, Ikeno Y, Yokoyama T, Kuwana M, Bolchi A, Ottonello S et al. (2003a) Secretory phospholipases A2 induce neurite outgrowth in PC12 cells. Biochem J 376:655-66
26. Nakashima S, Ikeno Y, Yokoyama T, Kuwana M, Bolchi A, Ottonello S et al. (2003b) Secretory phospholipases A 2 induce neurite outgrowth in PC12 cells. Biochem J 376:655-66
27. Nakazawa K, Nakazawa H, Sahuc F, Damour O, Collombel C (1996) Effects of calphostin C, specific PKC inhibitor on TPA-induced normal human melanocyte growth, morphology and adhesion. Pigment Cell Res 9:28-34
28. Noda Y, Takeya R, Ohno S, Naito S, Ito T, Sumimoto H (2001) Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42 to atypical protein kinase C. Genes Cells 6:107-19
29. Oka M, Ogita K, Ando H, Horikawa T, Hayashibe K, Saito N et al. (1996) Deletion of specific protein kinase C subspecies in human melanoma cells. J Cell Physiol 167:406-12
30. Oka M, Ogita K, Ando H, Kikkawa U, Ichihashi M (1995) Differential downregulation of protein kinase C subspecies in normal human melanocytes: possible involvement of the zeta subspecies in growth regulation. J Invest Dermatol 105:567-71
31. Ono Y, Fujii T, Ogita K, Kikkawa U, Igarashi K, Nishizuka Y (1989) Protein kinase C zeta subspecies from rat brain: its structure, expression, and properties. Proc Natl Acad Sci USA 86:3099-103
32. Park HY, Perez JM, Laursen R, Hara M, Gilchrest BA (1999) Protein kinase C-beta activates tyrosinase by phosphorylating serine residues in its cytoplasmic domain. J Biol Chem 274:16470-8
33. Powell MB, Rosenberg RK, Graham MJ, Birch ML, Yamanishi DT, Buckmeier JA et al. (1993) Protein kinase C beta expression in melanoma cells and melanocytes: differential expression correlates with biological responses to 12-O-tetradecanoylphorbol 13-acetate. J Cancer Res Clin Oncol 119:199-206
34. Qiu RG, Abo A, Steven Martin G (2000) A human homolog of the C. elegans polarity determinant Par-6 links Rac and Cdc42 to PKCzeta signaling and cell transformation. Curr Biol 10:697-707
35. Raftopoulou M, Hall A (2004) Cell migration: Rho GTPases lead the way. Dev Biol 265:23-32
36. Ridley AJ, Paterson HF, Johnston CL, Diekmann D, Hall A (1992) The small GTP-binding protein rac regulates growth factor-induced membrane ruffling. Cell 70:401-10
37. Sanz-Navares E, Fernandez N, Kazanietz MG, Rotenberg SA (2001) Atypical protein kinase Czeta suppresses migration of mouse melanoma cells. Cell Growth Differ 12:517-24
38. Schadow A, Scholz-Pedretti K, Lambeau G, Gelb MH, Furstenberger G, Pfeilschifter J et al. (2001) Characterization of group X phospholipase A(2) as the major enzyme secreted by human keratinocytes and its regulation by the phorbol ester TPA. J Invest Dermatol 116:31-9
39. Scott G (2002) Rac and rho: the story behind melanocyte dendrite formation. Pigment Cell Res 15:322-30
40. Scott G, Leopardi S (2003) The cAMP signaling pathway has opposing effects on Rac and Rho in B16F10 cells: implications for dendrite formation in melanocytic cells. Pigment Cell Res 16:139-48
41. Scott G, Leopardi S, Printup S, Madden BC (2002) Filopodia are conduits for melanosome transfer to keratinocytes. J Cell Sci 115:1441-51
42. Scott GA, Cassidy L (1998) Rac1 mediates dendrite formation in response to melanocyte stimulating hormone and ultraviolet light in a murine melanoma model. J Invest Dermatol 111:243-50
43. Scott GA, Jacobs SE, Pentland AP (2006) sPLA2-X stimulates cutaneous melanocyte dendricity and pigmentation through a lysophosphatidylcholine- dependent mechanism. J Invest Dermatol 126:855-61
44. Valentin E, Lambeau G (2000) Increasing molecular diversity of secreted phospholipases A(2) and their receptors and binding proteins. Biochim Biophys Acta 1488:59-70
45. Vemuri B, Singh SS (2001) Protein kinase C isozyme-specific phosphorylation of profilin. Cell Signal 13:433-9
46. Wooten MW, Zhou G, Seibenhener ML, Coleman ES (1994) A role for zeta protein kinase C in nerve growth factor-induced differentiation of PC12 cells. Cell Growth Differ 5:395-403
47. Yang LV, Radu CG, Wang L, Riedinger M, Witte ON (2005) Gi-independent macrophage chemotaxis to lysophosphatidylcholine via the immunoregulatory GPCR G2A. Blood 105:1127-34