메뉴 건너뛰기




Volumn 24, Issue 1, 2004, Pages 273-279

Immunohistochemical Dihydropyrimidine Dehydrogenase Expression Is A Good Prognostic Indicator for Patients with Dukes' C Colorectal Cancer

Author keywords

Colorectal cancer; Dihydropyrimidine dehydrogenase; Disease free survival; Enzymatic activity; Immunohistochemical expression

Indexed keywords

CARMOFUR; DIHYDROPYRIMIDINE DEHYDROGENASE; DOXIFLURIDINE; FLUOROURACIL; UFT;

EID: 1442277085     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (16)

References (24)
  • 1
    • 0028019880 scopus 로고
    • Thymidylate synthase inhibition after administration of fluorouracil with or without leucovorin in colon cancer patients: Implications for treatment with fluorouracil
    • Peters GJ, van der Wilt CL, van Groeningen CJ, Smid K, Meijer S and Pinedo HM: Thymidylate synthase inhibition after administration of fluorouracil with or without leucovorin in colon cancer patients: Implications for treatment with fluorouracil. J Clin Oncol 12: 2035-2042, 1994.
    • (1994) J Clin Oncol , vol.12 , pp. 2035-2042
    • Peters, G.J.1    Van Der Wilt, C.L.2    Van Groeningen, C.J.3    Smid, K.4    Meijer, S.5    Pinedo, H.M.6
  • 2
    • 0028281781 scopus 로고
    • 5-Ethynyluracil (776C85): Modulation of 5-fluorouracil efficacy and therapeutic index in rats bearing advanced colorectal carcinoma
    • Cao S, Rustum YM and Spector T: 5-Ethynyluracil (776C85): Modulation of 5-fluorouracil efficacy and therapeutic index in rats bearing advanced colorectal carcinoma. Cancer Res 54: 1507-1510, 1994.
    • (1994) Cancer Res , vol.54 , pp. 1507-1510
    • Cao, S.1    Rustum, Y.M.2    Spector, T.3
  • 3
    • 0030883708 scopus 로고    scopus 로고
    • Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted-infusion fluorouracil and weekly leucovorin
    • Leichman CG, Lenz HJ, Leichman L, Danenberg K, Baranda J, Groshen S, Boswell W, Metzger R, Tan M and Danenberg PV: Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted-infusion fluorouracil and weekly leucovorin. J Clin Oncol 15: 3223-3229, 1997.
    • (1997) J Clin Oncol , vol.15 , pp. 3223-3229
    • Leichman, C.G.1    Lenz, H.J.2    Leichman, L.3    Danenberg, K.4    Baranda, J.5    Groshen, S.6    Boswell, W.7    Metzger, R.8    Tan, M.9    Danenberg, P.V.10
  • 5
    • 0032864482 scopus 로고    scopus 로고
    • The expression of thymidine phosphorylase correlates with angiogenesis and the efficacy of chemotherapy using fluorouracil derivatives in advanced gastric carcinoma
    • Saito H, Tsujitani S, Oka S, Kondo A, Ikeguchi M, Maeda M and Kaibara N: The expression of thymidine phosphorylase correlates with angiogenesis and the efficacy of chemotherapy using fluorouracil derivatives in advanced gastric carcinoma. Br J Cancer 81: 484-489, 1999.
    • (1999) Br J Cancer , vol.81 , pp. 484-489
    • Saito, H.1    Tsujitani, S.2    Oka, S.3    Kondo, A.4    Ikeguchi, M.5    Maeda, M.6    Kaibara, N.7
  • 7
    • 0028097137 scopus 로고
    • A role for dihydropyrimidine dehydrogenase and thymidylate synthase in tumor sensitivity to fluorouracil
    • Beck A, Etienne MC, Chéradame S, Fischel JL, Formento P, Renée N and Milano G: A role for dihydropyrimidine dehydrogenase and thymidylate synthase in tumor sensitivity to fluorouracil. Eur J Cancer 30A: 1517-1522, 1994.
    • (1994) Eur J Cancer , vol.30 A , pp. 1517-1522
    • Beck, A.1    Etienne, M.C.2    Chéradame, S.3    Fischel, J.L.4    Formento, P.5    Renée, N.6    Milano, G.7
  • 9
    • 0030988930 scopus 로고    scopus 로고
    • Dihydropyrimidine dehydrogenase activity in hepatocellular carcinoma: Implication in 5-fluorouracil-based chemotherapy
    • Jiang W, Lu Z, He Y and Diasio RB: Dihydropyrimidine dehydrogenase activity in hepatocellular carcinoma: implication in 5-fluorouracil-based chemotherapy. Clin Cancer Res 3: 395-399, 1997.
    • (1997) Clin Cancer Res , vol.3 , pp. 395-399
    • Jiang, W.1    Lu, Z.2    He, Y.3    Diasio, R.B.4
  • 10
    • 0032438744 scopus 로고    scopus 로고
    • Dihydropyrimidine dehydrogenase but not thymidylate synthase expression is associated with resistance to 5-fluorouracil in colorectal cancer
    • Nita ME, Tominaga O, Nagawa H, Tsuruo T and Muto T: Dihydropyrimidine dehydrogenase but not thymidylate synthase expression is associated with resistance to 5-fluorouracil in colorectal cancer. Hepatogastroenterol 45: 2117-2122, 1998.
    • (1998) Hepatogastroenterol , vol.45 , pp. 2117-2122
    • Nita, M.E.1    Tominaga, O.2    Nagawa, H.3    Tsuruo, T.4    Muto, T.5
  • 11
    • 0033090335 scopus 로고    scopus 로고
    • Dihydropyrimidine dehydrogenase, multidrug resistance-associated protein, and thymidylate synthase gene expression levels can predict 5-fluorouracil resistance in human gastrointestinal cancer cells
    • Kirihara Y, Yamamoto W, Toge T and Nishiyama M: Dihydropyrimidine dehydrogenase, multidrug resistance-associated protein, and thymidylate synthase gene expression levels can predict 5-fluorouracil resistance in human gastrointestinal cancer cells. Int J Oncol 14: 551-556, 1999.
    • (1999) Int J Oncol , vol.14 , pp. 551-556
    • Kirihara, Y.1    Yamamoto, W.2    Toge, T.3    Nishiyama, M.4
  • 12
    • 0032945491 scopus 로고    scopus 로고
    • Dihydropyrimidine dehydrogenase activity and messenger RNA level may be related to the antitumor effect of 5-fluorouracil on human tumor xenografts in nude mice
    • Ishikawa Y, Kubota T, Otani Y, Watanabe M, Teramoto T, Kumai K, Kitajima M, Takechi T, Okabe H and Fukushima M: Dihydropyrimidine dehydrogenase activity and messenger RNA level may be related to the antitumor effect of 5-fluorouracil on human tumor xenografts in nude mice. Clin Cancer Res 5: 883-889, 1999.
    • (1999) Clin Cancer Res , vol.5 , pp. 883-889
    • Ishikawa, Y.1    Kubota, T.2    Otani, Y.3    Watanabe, M.4    Teramoto, T.5    Kumai, K.6    Kitajima, M.7    Takechi, T.8    Okabe, H.9    Fukushima, M.10
  • 13
    • 0032745499 scopus 로고    scopus 로고
    • Relationship between intratumoral dihydropyrimidine dehydrogenase activity and gene expression in human colorectal cancer
    • Uetake H, Ichikawa W, Takechi T, Fukushima M, Nihei Z and Sugihara K: Relationship between intratumoral dihydropyrimidine dehydrogenase activity and gene expression in human colorectal cancer. Clin Cancer Res 5: 2836-2839, 1999.
    • (1999) Clin Cancer Res , vol.5 , pp. 2836-2839
    • Uetake, H.1    Ichikawa, W.2    Takechi, T.3    Fukushima, M.4    Nihei, Z.5    Sugihara, K.6
  • 14
    • 0034813250 scopus 로고    scopus 로고
    • Variations in 5-fluorouracil concentrations of colorectal tissues as compared with dihydropyrimidine dehydrogenase (DPD) enzyme activities and DPD messenger RNA levels
    • Tanaka-Nozaki M, Onda M, Tanaka N and Kato S: Variations in 5-fluorouracil concentrations of colorectal tissues as compared with dihydropyrimidine dehydrogenase (DPD) enzyme activities and DPD messenger RNA levels. Clin Cancer Res 7: 2783-2787, 2001.
    • (2001) Clin Cancer Res , vol.7 , pp. 2783-2787
    • Tanaka-Nozaki, M.1    Onda, M.2    Tanaka, N.3    Kato, S.4
  • 15
    • 0036064015 scopus 로고    scopus 로고
    • Intratumoral dihydropyrimidine dehydrogenase messenger RNA level reflects tumor progression in human colorectal cancer
    • Shirota Y, Ichikawa W, Uetake H, Yamada H, Nihei Z and Sugihara K: Intratumoral dihydropyrimidine dehydrogenase messenger RNA level reflects tumor progression in human colorectal cancer. Ann Surg Oncol 9: 599-603, 2002.
    • (2002) Ann Surg Oncol , vol.9 , pp. 599-603
    • Shirota, Y.1    Ichikawa, W.2    Uetake, H.3    Yamada, H.4    Nihei, Z.5    Sugihara, K.6
  • 16
    • 0034000054 scopus 로고    scopus 로고
    • Characterization of dihydropyrimidine dehydrogenase on immunohistochemistry in colon carcinoma, and correlation between immunohistochemical score and protein level or messenger RNA expression
    • Takenoue T, Kitayama J, Takei Y, Umetani N, Matsuda K, Nita ME, Hatano K, Tsuruo T and Nagawa H: Characterization of dihydropyrimidine dehydrogenase on immunohistochemistry in colon carcinoma, and correlation between immunohistochemical score and protein level or messenger RNA expression. Ann Oncol 11: 273-279, 2002.
    • (2002) Ann Oncol , vol.11 , pp. 273-279
    • Takenoue, T.1    Kitayama, J.2    Takei, Y.3    Umetani, N.4    Matsuda, K.5    Nita, M.E.6    Hatano, K.7    Tsuruo, T.8    Nagawa, H.9
  • 19
    • 0000352810 scopus 로고
    • The spread of rectal cancer and its effect on prognosis
    • Dukes CE and Bussey HJR: The spread of rectal cancer and its effect on prognosis. Br J Cancer 12: 309-320, 1958.
    • (1958) Br J Cancer , vol.12 , pp. 309-320
    • Dukes, C.E.1    Bussey, H.J.R.2
  • 22
    • 0026045814 scopus 로고
    • A comparison of 5-fluorouracil metabolism in human colorectal cancer and colon mucosa
    • Peters GJ, van Groeningen CJ, Laurensse EJ and Pinedo HM: A comparison of 5-fluorouracil metabolism in human colorectal cancer and colon mucosa. Cancer 68: 1903-1909, 1991.
    • (1991) Cancer , vol.68 , pp. 1903-1909
    • Peters, G.J.1    Van Groeningen, C.J.2    Laurensse, E.J.3    Pinedo, H.M.4
  • 23
    • 0032862086 scopus 로고    scopus 로고
    • Regulation of dihydropyrimidine dehydrogenase in colorectal cancer
    • Johnston SJ, Ridge SA, Cassidy J and McLeod HL: Regulation of dihydropyrimidine dehydrogenase in colorectal cancer. Clin Cancer Res 5: 2566-2570, 1999.
    • (1999) Clin Cancer Res , vol.5 , pp. 2566-2570
    • Johnston, S.J.1    Ridge, S.A.2    Cassidy, J.3    McLeod, H.L.4
  • 24
    • 0035068874 scopus 로고    scopus 로고
    • Clinical relevance of concentrations of both pyrimidine nucleoside phosphorylase (PyNPase) and dihydropyrimidine dehydrogenase (DPD) in colorectal cancer
    • Hiroyasu S, Shiraishi M, Samura H, Tokashiki H, Shimoji H, Isa T and Muto Y: Clinical relevance of concentrations of both pyrimidine nucleoside phosphorylase (PyNPase) and dihydropyrimidine dehydrogenase (DPD) in colorectal cancer. Jpn J Clin Oncol 31: 65-68, 2001.
    • (2001) Jpn J Clin Oncol , vol.31 , pp. 65-68
    • Hiroyasu, S.1    Shiraishi, M.2    Samura, H.3    Tokashiki, H.4    Shimoji, H.5    Isa, T.6    Muto, Y.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.