Indomethacin causes renal epithelial cell injury involving Mcl-1 down-regulation

Biochemical and Biophysical Research Communications

Volumn 380, Issue 3, 2009, Pages 531-536

  Ou, Yen Chuan ^a   Yang, Chi Rei ^a   Cheng, Chen Li ^a   Li, Jian Ri ^a   Raung, Shue Ling ^a   Hung, Yu Yeh ^a   Chen, Chun Jung ^a,b,c,d  

^a TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^c TUNGHAI UNIVERSITY   (Taiwan)

^d CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; Indomethacin; Mcl 1; Mitochondria

Indexed keywords

CASPASE 3; CYTOCHROME C; INDOMETACIN; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PROSTAGLANDIN SYNTHASE; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN MCL 1; STAT3 PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; EPITHELIUM CELL; KIDNEY CELL; KIDNEY INJURY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL SURVIVAL; DOWN-REGULATION; EPITHELIAL CELLS; INDOMETHACIN; KIDNEY TUBULES, PROXIMAL; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; STAT3 TRANSCRIPTION FACTOR;

EID: 60549089718     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.01.094     Document Type: Article

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