Antiproliferative effect of indomethacin on CML cells is related to the suppression of STATs/Bcl-XL signal pathway

Annals of Hematology

Volumn 85, Issue 7, 2006, Pages 443-449

  Zhang, Guangsen ^a   Fu, Yunbi ^b  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

CML; Indomethacin; JAK; K562cells; STAT

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INDOMETACIN; JANUS KINASE 2; PROTEIN BCL XL; STAT PROTEIN; STAT1 PROTEIN; STAT5 PROTEIN;

ARTICLE; BIOASSAY; BONE MARROW CELL; CANCER GROWTH; CELL PROLIFERATION; CELL STRAIN K 562; CELLULAR DISTRIBUTION; CHRONIC MYELOID LEUKEMIA; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; GENE REPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; LEUKEMIA CELL; MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING;

BCL-X PROTEIN; CELL DIVISION; HUMANS; INDOMETHACIN; K562 CELLS; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; LEUKEMIA, MYELOID, CHRONIC; SIGNAL TRANSDUCTION; STAT TRANSCRIPTION FACTORS; STAT1 TRANSCRIPTION FACTOR; TUMOR CELLS, CULTURED;

EID: 33747844633     PISSN: 09395555     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00277-006-0098-0     Document Type: Article

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