Synthesis of amidine and amide derivatives and their evaluation for anti-inflammatory and analgesic activities

European Journal of Medicinal Chemistry

Volumn 44, Issue 3, 2009, Pages 1010-1015

  Sondhi, Sham M ^a   Singh, Jaiveer ^a   Kumar, Ashok ^b   Jamal, Hyder ^c   Gupta, P P ^c  

^a INDIAN INSTITUTE OF TECHNOLOGY ROORKEE   (India)

^b LLRM MEDICAL COLLEGE   (India)

^c BRD MEDICAL COLLEGE   (India)

Author keywords

Amide; Amidine; Analgesic; Anti inflammatory; Microwave irradiation

Indexed keywords

2 (2,5 DIOXOIMIDAZOLIDIN 4 YL) N [3 (2 NITROPHENYL) 4 PHENYLTHIAZOL 2(3H) YLIDENE]ACETAMIDE; 2 (2,5 DIOXOIMIDAZOLIDIN 4 YL) N [3 (4 NITROPHENYL) 4 PHENYLTHIAZOL 2(3H) YLIDENE]ACETAMIDE; ACETYLSALICYLIC ACID; AMIDE; AMIDINE; ANALGESIC AGENT; ANTIINFLAMMATORY AGENT; HYDANTOIN DERIVATIVE; IBUPROFEN; N (4 PHENYL 3 2 TOLYLTHIAZOL 2(3H) YLIDENE)PICOLINAMIDINE; N [3 (2 METHOXYPHENYL) 4 PHENYLTHIAZOL 2(3H) YLIDENE]PICOLINAMIDINE; N [3 (2 NITROPHENYL) 4 PHENYLTHIAZOL 2(3H) YLIDENE] 2,6 DIOXO 1,2,3,6 TETRAHYDROPYRIMIDINE 4 CARBOXAMIDE; N [3 (2 NITROPHENYL) 4 PHENYLTHIAZOL 2(3H) YLIDENE]PICOLINAMIDINE; N [3 (4 ACETYLPHENYL) 4 PHENYLTHIAZOL 2(3H) YLIDENE] 2,6 DIOXO 1,2,3,6 TETRAHYDROPYRIMIDINE 4 CARBOXAMIDE; N [3 (4 ACETYLPHENYL) 4 PHENYLTHIAZOL 2(3H) YLIDENE]PICOLINAMIDINE; N [3 (4 CHLOROPHENYL) 4 PHENYLTHIAZOL 2(3H) YLIDENE] 2 (2,5 DIOXOIMIDAZOLIDIN 4 YL)ACETAMIDE; N [3 (4 CHLOROPHENYL) 4 PHENYLTHIAZOL 2(3H) YLIDENE] 2,6 DIOXO 1,2,3,6 TETRAHYDROPYRIMIDINE 4 CARBOXAMIDE; N [3 (4 CHLOROPHENYL) 4 PHENYLTHIAZOL 2(3H) YLIDENE]PICOLINAMIDINE; N [3 (4 METHOXYPHENYL) 4 PHENYLTHIAZOL 2(3H) YLIDENE]PICOLINAMIDINE; N [3 (4 METOXYPHENYL) 4 PHENYLTHIAZOL 2(3H) YLIDENE] 2,6 DIOXO 1,2,3,6 TETRAHYDROPYRIMIDINE 4 CARBOXAMIDE; N [3 (4 NITROPHENYL) 4 PHENYLTHIAZOL 2(3H) YLIDENE]PICOLINAMIDINE; N [4 (4 BROMOPHENYL) 3 (NAPHTHALEN 2 YL)THIAZOL 2(3H) YLIDENE]PICOLINAMIDINE; N [4 (4 ETHOXYPHENYL) 4 PHENYLTHIAZOL 2(3H) YLIDENE]PICOLINAMIDINE; N [4 (4 METHOXYPHENYL) 3 (4 NITROPHENYL)THIAZOL 2(3H) YLIDENE] 2,6 DIOXO 1,2,3,6 TETRAHYDROPYRIMIDINE 4 CARBOXAMIDE; OROTIC ACID; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; MOUSE; NONHUMAN; PAW EDEMA; POLYMERIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; STRUCTURE ACTIVITY RELATION;

AMIDES; AMIDINES; ANALGESICS; ANIMALS; ANTI-INFLAMMATORY AGENTS; DRUG EVALUATION, PRECLINICAL; FEMALE; MAGNETIC RESONANCE SPECTROSCOPY; MICE; RATS; SPECTROMETRY, MASS, FAST ATOM BOMBARDMENT; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 60549088884     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.06.029     Document Type: Article

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