Synthesis, anti-inflammatory and analgesic activities evaluation of some mono, bi and tricyclic pyrimidine derivatives

Bioorganic and Medicinal Chemistry

Volumn 13, Issue 22, 2005, Pages 6158-6166

  Sondhi, Sham M ^a   Singh, Nirupma ^a   Johar, Monika ^a   Kumar, Ashok ^b  

^a INDIAN INSTITUTE OF TECHNOLOGY ROORKEE   (India)

^b LLRM MEDICAL COLLEGE   (India)

Author keywords

Analgesic; Anti inflammatory; Bicyclic pyrimidine; Pyrimidine; Tricyclic pyrimidine

Indexed keywords

1 [(3 1H IMIDAZOL 1 YL)PROPYL] 6 HYDROXY 4 METHYLTETRAHYDROPYRIMIDINE 2(1H) THIONE; 2,3,4,4A TETRAHYDRO 3,3,4A TRIMETHYL 8 NITRO 1(H) PYRIMIDO[6,1 B]BENZOXAZOLE 1 THIONE; 2,3,4,4A TETRAHYDRO 4A METHYL 8 NITRO 1(H) PYRIMIDO[6,1 B]BENZOXAZOLE 1 THIONE; 3 (4,4,6 TRIMETHYL 2 THIOXO 3,4 DIHYDROPYRIMIDIN 1(2H) YL)BENZONITRILE; 4 METHOXY 4,6,6 TRIMETHYL 3 (4 PHENYLTHIAZOL 2 YL)TETRAHYDROPYRIMIDINE 2(1H) THIONE; 4,4,6 TRIMETHYL 1 (4 PHENYLTHIAZOL 2 YL) 3,4 DIHYDROPYRIMIDINE 2(1H) THIONE; 4,4,6 TRIMETHYL 3,4 DIHYDROPYRIMIDINE 2(1H) THIONE; 7 METHYL 5 THIOXO 1,5,6,7,8,8A HEXAHYDROIMIDAZO[1,2 F]PYRIMIDINE 2,3 DICARBONITRILE; 7,7,8A TRIMETHYL 5 THIOXO 1,5,6,7,8,8A HEXAHYDROIMIDAZO[1,2 F]PYRIMIDINE 2,3 DICARBONITRILE; 7,7,8A TRIMETHYL 5 THIOXOOCTAHYDROIMIDAZO[1,2 F]PYRIMIDINE 2 CARBOXYLIC ACID; IBUPROFEN; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; INFRARED SPECTROSCOPY; NONHUMAN; PAW EDEMA; POLYMERIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; WRITHING TEST;

ANALGESICS; ANIMALS; ANTI-INFLAMMATORY AGENTS; DRUG EVALUATION, PRECLINICAL; FEMALE; IBUPROFEN; MICE; PYRIMIDINES; RATS;

EID: 25844440862     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.06.063     Document Type: Article

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