Synthesis and biological evaluation of new cyclic amidine analogs of chlorambucil

Farmaco

Volumn 59, Issue 2, 2004, Pages 111-117

  Bielawska, Anna ^a   Bielawski, Krzysztof ^a   Muszyńska, Anna ^a  

^a MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

Author keywords

Chlorambucil; Cytotoxicity; DNA binding; DNA topoisomerase II; MCF 7; MDA MB 231

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 5 [4 (3,4,5,6 TETRAHYDRO 1H PYRIMIDIN 2 YL)PHENYL] 2 FURANCARBOXYLIC ACID; AMIDE; AMIDINE; ANTINEOPLASTIC AGENT; CHLORAMBUCIL; DNA TOPOISOMERASE; ETHYL 5 [4 (3,4,5,6 TETRAHYDRO 1H PYRIMIDIN 2 YL)PHENYL] 2 FURANCARBOXYLATE; N (2 AMINOETHYL) 5 [4 (3,4,5,6 TETRAHYDRO 1H PYRIMIDIN 2 YL)PHENYL] 2 FURANCARBOXAMIDE; N (2 AMINOETHYL) 5 [4 (4,5 DIHYDRO 1H IMIDAZOL 2 YL)PHENYL] 2 FURANCARBOXAMIDE; N [2 [4 [4 BIS(2 CHLOROETHYL)AMINOPHENYL]BUTYRYL]AMINOETHYL] 5 [4 (3,4,5,6 TETRAHYDRO 1H PYRIMIDIN 2 YL)PHENYL] 2 FURANCARBOXAMIDE; N [2 [4 [4 BIS(2 CHLOROETHYL)AMINOPHENYL]BUTYRYL]AMINOETHYL] 5 [4 (4,5 DIHYDRO 1H IMIDAZOL 2 YL)PHENYL] 2 FURANCARBOXAMIDE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BREAST CANCER; CANCER CELL; CATALYSIS; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOTOXICITY; DNA BINDING; DRUG POTENCY; DRUG SYNTHESIS; EVALUATION; HUMAN; HUMAN CELL;

EID: 1042278873     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.farmac.2003.12.002     Document Type: Article

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