Chemical genetics hits "reality"

Science

Volumn 306, Issue 5693, 2004, Pages 67-68

  Bellows, David S ^a   Tyers, Mike ^a  

^a MOUNT SINAI HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; BORTEZOMIB; CELL CYCLE PROTEIN; CYCLIN B; CYCLINE; LIGASE; ORNITHINE DECARBOXYLASE; PROTEASOME; PROTEASOME INHIBITOR; UBIQUITIN; UBIQUITIN PROTEIN LIGASE; UBISTATIN A; UBISTATIN B; UNCLASSIFIED DRUG; BETA CATENIN; BETA CATENIN PROTEIN, XENOPUS; BETA-CATENIN PROTEIN, XENOPUS; CTNNB1 PROTEIN, HUMAN; CYSTEINE PROTEINASE; CYTOSKELETON PROTEIN; HYBRID PROTEIN; MULTIENZYME COMPLEX; PROTEIN; QUINOLINE DERIVATIVE; SACCHAROMYCES CEREVISIAE PROTEIN; SIC1 PROTEIN, S CEREVISIAE; SULFANILIC ACID DERIVATIVE; TRANSACTIVATOR PROTEIN; XENOPUS PROTEIN;

BIOLOGY;

CHEMICAL GENETICS; DRUG INHIBITION; DRUG MECHANISM; DRUG TARGETING; ENZYME DEGRADATION; ENZYME INHIBITION; ENZYME SPECIFICITY; EUKARYOTIC CELL; FROG; GENE DELETION; GENE LIBRARY; GENE MUTATION; GENETIC SCREENING; HUMAN; MULTIPLE MYELOMA; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; REVIEW; UBIQUITINATION; ANIMAL; DRUG ANTAGONISM; DRUG SCREENING; INTERPHASE; METABOLISM; MITOSIS; NEOPLASM; NOTE; OOCYTE; PATHOLOGY; PROTEIN BINDING; XENOPUS;

ANURA; EUKARYOTA;

ANIMALS; BETA CATENIN; CYCLIN B; CYSTEINE ENDOPEPTIDASES; CYTOSKELETAL PROTEINS; DRUG EVALUATION, PRECLINICAL; HUMANS; INTERPHASE; MITOSIS; MULTIENZYME COMPLEXES; NEOPLASMS; OOCYTES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEINS; QUINOLINES; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS; SULFANILIC ACIDS; TRANS-ACTIVATORS; UBIQUITIN; XENOPUS; XENOPUS PROTEINS;

EID: 6044241906     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1104611     Document Type: Review

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