Up-regulation of myometrial RHO effector proteins (PKN1 and DIAPH1) and CPI-17 (PPP1R14A) phosphorylation in human pregnancy is associated with increased GTP-RHOA in spontaneous preterm labor

Biology of Reproduction

Volumn 76, Issue 6, 2007, Pages 971-982

  Lartey, J ^a   Smith, M ^a   Pawade, J ^a   Strachan, B ^a   Mellor, H ^a   Lopez Bernal A ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

DIAPH1; Female reproductive tract; Oxytocin; Parturition; PKN1; RHO; Uterus

Indexed keywords

ACTIN; BINDING PROTEIN; CALCIUM; MESSENGER RNA; MYOSIN; MYOSIN LIGHT CHAIN; MYOSIN LIGHT CHAIN PHOSPHATASE; PROTEIN; PROTEIN CPI 17; PROTEIN DIAPH1; PROTEIN DIAPH2; PROTEIN KINASE C; PROTEIN KINASE N; PROTEIN KINASE N1; PROTEIN SUBUNIT; RHO FACTOR; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; RHOB GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ACTIN MYOSIN INTERACTION; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; MYOMETRIUM; PREGNANCY; PREMATURE LABOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; UPREGULATION; UTERUS CONTRACTILITY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CELLS, CULTURED; FEMALE; HUMANS; MODELS, BIOLOGICAL; MYOMETRIUM; OBSTETRIC LABOR, PREMATURE; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLATION; PREGNANCY; PROTEIN KINASE C; RHO GTP-BINDING PROTEINS; RHOA GTP-BINDING PROTEIN; RHOB GTP-BINDING PROTEIN; RNA, MESSENGER; TERM BIRTH; UP-REGULATION;

EID: 34249672284     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod.106.058982     Document Type: Article

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