Antiplasmodial and antitrypanosomal activities of aminobicyclo[2.2.2]octyl ω-aminoalkanoates

European Journal of Medicinal Chemistry

Volumn 44, Issue 2, 2009, Pages 736-744

  Schlapper, Christian ^a   Seebacher, Werner ^a   Faist, Johanna ^a   Kaiser, Marcel ^b   Brun, Reto ^b   Saf, Robert ^c   Weis, Robert ^a  

^a UNIVERSITY OF GRAZ   (Austria)

^b SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

^c Erzherzog Johann University   (Austria)

Author keywords

4 Aminobicyclo 2.2.2 octane derivative; Bicyclo octyl ester; In vitro assay; Plasmodium falciparum; Trypanosoma brucei rhodesiense

Indexed keywords

4 DIMETHYLAMINO 6,7 DIPHENYLBICYCLO[2.2.2]OCTAN 2 YL 2 (4 HYDROXYPIPERIDINO)ACETATE; 4 DIMETHYLAMINO 6,7 DIPHENYLBICYCLO[2.2.2]OCTAN 2 YL 3 (4 HYDROXYPIPERIDINO)PROPIONATE; 4 DIMETHYLAMINO 6,7 DIPHENYLBICYCLO[2.2.2]OCTAN 2 YL 3 DIETHYLAMINOPROPIONATE; 4 DIMETHYLAMINO 6,7 DIPHENYLBICYCLO[2.2.2]OCTAN 2 YL 3 PIPERIDINOPROPIONATE; 4 DIMETHYLAMINO 6,7 DIPHENYLBICYCLO[2.2.2]OCTAN 2 YL 3 PYRROLIDINOPROPIONATE; 6,7 DIPHENYL 4 PIPERIDINOBICYCLO[2.2.2]OCTAN 2 YL 2 (4 HYDROXYPIPERIDINO)ACETATE; 6,7 DIPHENYL 4 PIPERIDINOBICYCLO[2.2.2]OCTAN 2 YL 2' DIETHYLAMINOACETATE; 6,7 DIPHENYL 4 PIPERIDINOBICYCLO[2.2.2]OCTAN 2 YL 2' PIPERIDINOACETATE; 6,7 DIPHENYL 4 PIPERIDINOBICYCLO[2.2.2]OCTAN 2 YL 2' PYRROLIDINOACETATE; 6,7 DIPHENYL 4 PIPERIDINOBICYCLO[2.2.2]OCTAN 2 YL 3 (4 HYDROXYPIPERIDINO)PROPIONATE; 6,7 DIPHENYL 4 PIPERIDINOBICYCLO[2.2.2]OCTAN 2 YL 3 DIETHYLAMINOPROPIONATE; 6,7 DIPHENYL 4 PIPERIDINOBICYCLO[2.2.2]OCTAN 2 YL 3 PIPERIDINOPROPIONATE; 6,7 DIPHENYL 4 PIPERIDINOBICYCLO[2.2.2]OCTAN 2 YL 3 PYRROLIDINOPROPIONATE; 6,7 DIPHENYL 4 PYRROLIDINOBICYCLO[2.2.2]OCTAN 2 YL 2 (4 HYDROXYPIPERIDINO)ACETATE; 6,7 DIPHENYL 4 PYRROLIDINOBICYCLO[2.2.2]OCTAN 2 YL 3 (4 HYDROXYPIPERIDINO)PROPIONATE; 6,7 DIPHENYL 4 PYRROLIDINOBICYCLO[2.2.2]OCTAN 2 YL 3 DIETHYLAMINOPROPIONATE; 6,7 DIPHENYL 4 PYRROLIDINOBICYCLO[2.2.2]OCTAN 2 YL 3 PIPERIDINOPROPIONATE; 6,7 DIPHENYL 4 PYRROLIDINOBICYCLO[2.2.2]OCTAN 2 YL 3 PYRROLIDINOPROPIONATE; ANTIPROTOZOAL AGENT; CHLOROQUINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANTIPROTOZOAL ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CHEMICAL STRUCTURE; DRUG SYNTHESIS; NONHUMAN; PLASMODIUM FALCIPARUM; STRUCTURE ACTIVITY RELATION; TRYPANOSOMA RHODESIENSE;

ANIMALS; ANTIPROTOZOAL AGENTS; BICYCLO COMPOUNDS; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOCIDAL AGENTS; TRYPANOSOMA BRUCEI RHODESIENSE;

EID: 60149092174     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.05.002     Document Type: Article

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