New 4-aminobicyclo[2.2.2]octane derivatives and their activities against Plasmodium falciparum and Trypanosoma b. rhodesiense

European Journal of Pharmaceutical Sciences

Volumn 21, Issue 2-3, 2004, Pages 225-233

  Seebacher, Werner ^a   Brun, Reto ^b   Weis, Robert ^a  

^a UNIVERSITY OF GRAZ   (Austria)

^b SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

Author keywords

4 Aminobicyclo 2.2.2 octane derivatives; Benzenesulfonates; In vitro assays; Plasmodium falciparum; Thiosemicarbazones; Trypanosoma b. rhodesiense

Indexed keywords

2 [N' (4 MORPHOLINO 6,7 DIPHENYLBICYCLO[2.2.2]OCTAN 2 YLIDENE)HYDRAZONO] 1,3 THIAZOLIDIN 4 ONE HYDROBROMIDE; 2 [N' (6,7 DIPHENYL 4 PYRROLIDINOBICYCLO[2.2.2]OCTAN 2 YLIDENE)HYDRAZONO] 1,3 THIAZOLIDIN 4 ONE HYDROBROMIDE; 4 DIMETHYLAMINO 6,7 DIPHENYLBICYCLO[2.2.2]OCTAN 2 ONE THIOSEMICARBAZONE; 4 DIMETHYLAMINO 6,7 DIPHENYLBICYCLO[2.2.2]OCTAN 2 YL 4 TERT BUTYLBENZENESULFONATE; 4 DIMETHYLAMINO 6,7 DIPHENYLBICYCLO[2.2.2]OCTAN 2 YLTOLUENE 4 SULFONATE; 4 MORPHOLINO 6,7 DIPHENYLBICYCLO[2.2.2]OCTAN 2 ONE THIOSEMICARBAZONE; 4 MORPHOLINO 6,7 DIPHENYLBICYCLO[2.2.2]OCTAN 2 YL 4 TERT BUTYLBENZENESULFONATE; 4 MORPHOLINO 6,7 DIPHENYLBICYCLO[2.2.2]OCTAN 2 YLTOLUENE 4 SULFONATE; 6,7 DIPHENYL 4 PIPERIDINOBICYCLO[2.2.2]OCTAN 2 ONE THIOSEMICARBAZONE; 6,7 DIPHENYL 4 PIPERIDINOBICYCLO[2.2.2]OCTAN 2 YL 4 TERT BUTYLBENZENESULFONATE; 6,7 DIPHENYL 4 PIPERIDINOBICYCLO[2.2.2]OCTAN 2 YLTOLUENE 4 SULFONATE; 6,7 DIPHENYL 4 PYRROLIDINOBICYCLO[2.2.2]OCTAN 2 ONE THIOSEMICARBAZONE; 6,7 DIPHENYL 4 PYRROLIDINOBICYCLO[2.2.2]OCTAN 2 YL 4 TERT BUTYLBENZENESULFONATE; 6,7 DIPHENYL 4 PYRROLIDINOBICYCLO[2.2.2]OCTAN 2 YLTOLUENE 4 SULFONATE; ANTIMALARIAL AGENT; ANTITRYPANOSOMAL AGENT; BICYCLO[2.2.2]OCTANE DERIVATIVE; CHLOROQUINE; PYRIMETHAMINE; SURAMIN; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ANTIPROTOZOAL ACTIVITY; ARTICLE; ASSAY; CONTROLLED STUDY; DRUG POTENCY; DRUG SCREENING; EXPERIMENTAL TEST; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; TRYPANOSOMA RHODESIENSE;

EID: 0842308202     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2003.10.011     Document Type: Article

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