Ritonavir impairs lipoprotein lipase-mediated lipolysis and decreases uptake of fatty acids in adipose tissue

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 26, Issue 1, 2006, Pages 124-129

  Den Boer, Marion A M ^a,b   Berbée, Jimmy F P ^a,b   Reiss, Peter ^c   Van Der Valk, Marc ^c   Voshol, Peter J ^a,b   Kuipers, Folkert ^d   Havekes, Louis M ^a,b   Rensen, Patrick C N ^a,b   Romijn, Johannes A ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b TNO   (Netherlands)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

^d UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Dyslipidemia; FA metabolism; Protease inhibitor; TG metabolism; Transgenic mice

Indexed keywords

ALBUMIN; APOLIPOPROTEIN E3; LIPOPROTEIN LIPASE; PROTEINASE INHIBITOR; RITONAVIR; TRIACYLGLYCEROL; TRIOLEIN; VERY LOW DENSITY LIPOPROTEIN; ANTICOAGULANT AGENT; APOLIPOPROTEIN E; APOLIPOPROTEIN E3 (LEIDEIN); DIAGNOSTIC AGENT; FATTY ACID; HEPARIN; TRITIUM; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ADIPOSE TISSUE; ANIMAL TISSUE; ARTICLE; CLEARANCE; CONTROLLED STUDY; DRUG MECHANISM; EMULSION; ENZYME ACTIVITY; FAT INTAKE; FATTY ACID METABOLISM; FATTY ACID TRANSPORT; FEMALE; HALF LIFE TIME; HYPERTRIGLYCERIDEMIA; LIPID DIET; LIPODYSTROPHY; LIPOLYSIS; MOUSE; NONHUMAN; POSTPRANDIAL STATE; PRIORITY JOURNAL; TRANSGENIC MOUSE; TRIACYLGLYCEROL BLOOD LEVEL; ANIMAL; BIOSYNTHESIS; BLOOD; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; ENZYME ACTIVATION; GENETICS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; METABOLISM;

ADIPOSE TISSUE; ANIMALS; ANTICOAGULANTS; APOLIPOPROTEIN E3; APOLIPOPROTEINS E; CHOLESTEROL, VLDL; EMULSIONS; ENZYME ACTIVATION; FATTY ACIDS; FEMALE; HEPARIN; HIV INFECTIONS; HIV PROTEASE INHIBITORS; HYPERTRIGLYCERIDEMIA; LIPOLYSIS; LIPOPROTEIN LIPASE; MICE; MICE, TRANSGENIC; POSTPRANDIAL PERIOD; RITONAVIR; TRIGLYCERIDES; TRIOLEIN; TRITIUM;

EID: 33644828770     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.0000194073.87647.10     Document Type: Article

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