Inhibition of adipocyte differentiation by HIV protease inhibitors

Journal of Clinical Endocrinology and Metabolism

Volumn 84, Issue 11, 1999, Pages 4274-4277

  Zhan, Bei ^a   Macnual, Karen ^a   Szalkowski, Deborah ^a   Li, Zhihua ^a   Berger, Joel ^a   Moller, David E ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINASE INHIBITOR;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADIPOCYTE; ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CELL DIFFERENTIATION; DRUG EFFECT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LIPODYSTROPHY; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS;

EID: 0033346649     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jcem.84.11.6234     Document Type: Article

References (12)

1. A syndrome of peripheral lipodystrophy, hyperlipidemia and insulin resistance in patients receiving HIV protease inhibitors
2. Development of cervical fat pads following therapy with human immunodeficiency virus type 1 protease inhibitors
3. Pathogenesis of HIV-1-protease inhibitor-associated peripheral lipodystrophy, hyperlipidaemia, and insulin resistance
4. Syndromes of severe insulin resistance: Clinical and pathophysiological features
5. Regulation of adipocyte gene expression and differentiation by peroxisome proliferator activated receptor γ
6. Novel peroxisome proliferator-activated receptor (PPAR) γ and PPARδ ligands produce distinct biological effects
7. Sublines of mouse 3T3 cells that accumulate lipid
8. Quantitation of adipose conversion and triglycerides by staining intracytoplasmic lipids with Oil red O
9. PPARα and PPARγ activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene
10. AdipoQ is a novel adipose-specific gene dysregulated in obesity
11. Protease inhibitors and adipocyte differentiation in cell culture
12. Alterations in body fat distribution in HIV-infected men and wonen