-
2
-
-
0018888679
-
Treatment of Crohn's disease with 6-mercaptopurine. A long-term, randomized, double-blind study
-
Present DH, Korelitz BI, Wisch N, et al. Treatment of Crohn's disease with 6-mercaptopurine. A long-term, randomized, double-blind study. N Engl J Med. 1980;302:981-987.
-
(1980)
N Engl J Med
, vol.302
, pp. 981-987
-
-
Present, D.H.1
Korelitz, B.I.2
Wisch, N.3
-
3
-
-
0028899859
-
Methotrexate for the treatment of Crohn's disease. The North American Crohn's Study Group Investigators
-
Feagan BG, Rochon J, Fedorak RN, et al. Methotrexate for the treatment of Crohn's disease. The North American Crohn's Study Group Investigators. N Engl J Med. 1995;332:292-297.
-
(1995)
N Engl J Med
, vol.332
, pp. 292-297
-
-
Feagan, B.G.1
Rochon, J.2
Fedorak, R.N.3
-
4
-
-
0036197644
-
Toxicity of mycophenolate mofetil in patients with inflammatory bowel disease
-
Skelly MM, Logan RF, Jenkins D, et al. Toxicity of mycophenolate mofetil in patients with inflammatory bowel disease. Inflamm Bowel Dis. 2002;8:93-97.
-
(2002)
Inflamm Bowel Dis
, vol.8
, pp. 93-97
-
-
Skelly, M.M.1
Logan, R.F.2
Jenkins, D.3
-
5
-
-
0001647780
-
Treatment of ulcerative colitis with antimetabolites
-
Bean RHD. Treatment of ulcerative colitis with antimetabolites. Br Med J 1966:1081-1084.
-
(1966)
Br Med J
, pp. 1081-1084
-
-
Bean, R.H.D.1
-
6
-
-
0034891450
-
An open-label pilot study using thioguanine as a therapeutic alternative in Crohn's disease patients resistant to 6-mercaptopurine therapy
-
Dubinsky MC, Hassard PV, Seidman EG, et al. An open-label pilot study using thioguanine as a therapeutic alternative in Crohn's disease patients resistant to 6-mercaptopurine therapy. Inflamm Bowel Dis. 2001;7:181-189.
-
(2001)
Inflamm Bowel Dis
, vol.7
, pp. 181-189
-
-
Dubinsky, M.C.1
Hassard, P.V.2
Seidman, E.G.3
-
7
-
-
35448929759
-
6-Thioguanine associated nodular regenerative hyperplasia in patients with inflammatory bowel disease may induce portal hypertension
-
Ferlitsch A, Teml A, Reinisch W, et al. 6-Thioguanine associated nodular regenerative hyperplasia in patients with inflammatory bowel disease may induce portal hypertension. Am J Gastroenterol. 2007;102: 2495-2503.
-
(2007)
Am J Gastroenterol
, vol.102
, pp. 2495-2503
-
-
Ferlitsch, A.1
Teml, A.2
Reinisch, W.3
-
8
-
-
0043168014
-
6-Thioguanine can cause serious liver injury in inflammatory bowel disease patients
-
Dubinsky MC, Vasiliauskas EA, Singh H, et al. 6-Thioguanine can cause serious liver injury in inflammatory bowel disease patients. Gastroenterology. 2003;125:298-303.
-
(2003)
Gastroenterology
, vol.125
, pp. 298-303
-
-
Dubinsky, M.C.1
Vasiliauskas, E.A.2
Singh, H.3
-
9
-
-
33744490627
-
6-Thioguanine treatment in inflammatory bowel disease: A critical appraisal by a European 6-TG working party
-
de Boer NK, Reinisch W, Teml A, et al. 6-Thioguanine treatment in inflammatory bowel disease: a critical appraisal by a European 6-TG working party. Digestion. 2006;73:25-31.
-
(2006)
Digestion
, vol.73
, pp. 25-31
-
-
de Boer, N.K.1
Reinisch, W.2
Teml, A.3
-
10
-
-
33846266585
-
Toxicity of 6-thioguanine: No hepatotoxicity in a series of IBD patients treated with long-term, low dose 6-thioguanine. Some evidence for dose or metabolite level dependent effects?
-
Gilissen LP, Derijks LJ, Driessen A, et al. Toxicity of 6-thioguanine: no hepatotoxicity in a series of IBD patients treated with long-term, low dose 6-thioguanine. Some evidence for dose or metabolite level dependent effects? Dig Liver Dis. 2007;39:156-159.
-
(2007)
Dig Liver Dis
, vol.39
, pp. 156-159
-
-
Gilissen, L.P.1
Derijks, L.J.2
Driessen, A.3
-
11
-
-
0028821156
-
Determination of intracellular levels of 6-mercaptopurine metabolites in erythrocytes utilizing capillary electrophoresis with laser-induced fluorescence detection
-
Rabel SR, Stobaugh JF, Trueworthy R. Determination of intracellular levels of 6-mercaptopurine metabolites in erythrocytes utilizing capillary electrophoresis with laser-induced fluorescence detection. Anal Biochem. 1995;224:315-322.
-
(1995)
Anal Biochem
, vol.224
, pp. 315-322
-
-
Rabel, S.R.1
Stobaugh, J.F.2
Trueworthy, R.3
-
12
-
-
0038805258
-
Thioguanine: A potential alternate thiopurine for IBD patients allergic to 6-mercaptopurine or azathioprine
-
Dubinsky MC, Feldman EJ, Abreu MT, et al. Thioguanine: a potential alternate thiopurine for IBD patients allergic to 6-mercaptopurine or azathioprine. Am J Gastroenterol. 2003;98:1058-1063.
-
(2003)
Am J Gastroenterol
, vol.98
, pp. 1058-1063
-
-
Dubinsky, M.C.1
Feldman, E.J.2
Abreu, M.T.3
-
13
-
-
12144285961
-
Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase)
-
Marinaki AM, Ansari A, Duley JA, et al. Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase). Pharmacogenetics. 2004;14:181-187.
-
(2004)
Pharmacogenetics
, vol.14
, pp. 181-187
-
-
Marinaki, A.M.1
Ansari, A.2
Duley, J.A.3
-
14
-
-
0036202803
-
6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease
-
Dubinsky MC, Yang H, Hassard PV, et al. 6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease. Gastroenterology. 2002;122:904-915.
-
(2002)
Gastroenterology
, vol.122
, pp. 904-915
-
-
Dubinsky, M.C.1
Yang, H.2
Hassard, P.V.3
-
15
-
-
0036180977
-
Azathioprine intolerance in patients with IBD may be imidazole-related and is independent of TPMT activity
-
McGovern DP, Travis SP, Duley J, et al. Azathioprine intolerance in patients with IBD may be imidazole-related and is independent of TPMT activity. Gastroenterology. 2002;122:838-839.
-
(2002)
Gastroenterology
, vol.122
, pp. 838-839
-
-
McGovern, D.P.1
Travis, S.P.2
Duley, J.3
-
16
-
-
0027361660
-
Red blood cell hypoxanthine phosphoribosyltransferase activity measured using 6-mercaptopurine as a substrate: A population study in children with acute lymphoblastic leukaemia
-
Lennard L, Hale JP, Lilleyman JS. Red blood cell hypoxanthine phosphoribosyltransferase activity measured using 6-mercaptopurine as a substrate: a population study in children with acute lymphoblastic leukaemia. Br J Clin Pharmacol. 1993;36:277-284.
-
(1993)
Br J Clin Pharmacol
, vol.36
, pp. 277-284
-
-
Lennard, L.1
Hale, J.P.2
Lilleyman, J.S.3
-
18
-
-
0025303034
-
Micronodular transformation (nodular regenerative hyperplasia) of the liver: A report of 64 cases among 2,500 autopsies and a new classification of benign hepatocellular nodules
-
Wanless IR. Micronodular transformation (nodular regenerative hyperplasia) of the liver: a report of 64 cases among 2,500 autopsies and a new classification of benign hepatocellular nodules. Hepatology (Baltimore). 1990;11:787-797.
-
(1990)
Hepatology (Baltimore)
, vol.11
, pp. 787-797
-
-
Wanless, I.R.1
-
19
-
-
0346998117
-
Early nodular hyperplasia of the liver occurring with inflammatory bowel diseases in association with thioguanine therapy
-
Shastri S, Dubinsky MC, Fred Poordad F, et al. Early nodular hyperplasia of the liver occurring with inflammatory bowel diseases in association with thioguanine therapy. Arch Pathol Lab Med. 2004;128:49-53.
-
(2004)
Arch Pathol Lab Med
, vol.128
, pp. 49-53
-
-
Shastri, S.1
Dubinsky, M.C.2
Fred Poordad, F.3
-
20
-
-
0036899613
-
Hepatic venoocclusive disease in blood and bone marrow transplantation in children and young adults: Incidence, risk factors, and outcome in a cohort of 241 patients
-
Reiss U, Cowan M, McMillan A, et al. Hepatic venoocclusive disease in blood and bone marrow transplantation in children and young adults: incidence, risk factors, and outcome in a cohort of 241 patients. J Pediatr Hematol Oncol. 2002;24:746-750.
-
(2002)
J Pediatr Hematol Oncol
, vol.24
, pp. 746-750
-
-
Reiss, U.1
Cowan, M.2
McMillan, A.3
-
21
-
-
0035044891
-
Hepatotoxicity of chemotherapy
-
King PD, Perry MC. Hepatotoxicity of chemotherapy. Oncologist. 2001; 6:162-176.
-
(2001)
Oncologist
, vol.6
, pp. 162-176
-
-
King, P.D.1
Perry, M.C.2
-
22
-
-
27244452424
-
Nodular regenerative hyperplasia and thiopurines: The case for level-dependent toxicity
-
de Boer NK, Mulder CJ, van Bodegraven AA. Nodular regenerative hyperplasia and thiopurines: the case for level-dependent toxicity. Liver Transpl. 2005;11:1300-1301.
-
(2005)
Liver Transpl
, vol.11
, pp. 1300-1301
-
-
de Boer, N.K.1
Mulder, C.J.2
van Bodegraven, A.A.3
-
23
-
-
30344466643
-
Chronic liver disease related to 6-thioguanine in children with acute lymphoblastic leukaemia
-
De Bruyne R, Portmann B, Samyn M, et al. Chronic liver disease related to 6-thioguanine in children with acute lymphoblastic leukaemia. J Hepatol. 2006;44:407-410.
-
(2006)
J Hepatol
, vol.44
, pp. 407-410
-
-
De Bruyne, R.1
Portmann, B.2
Samyn, M.3
-
24
-
-
33744495734
-
6-Thioguanine-related chronic hepatotoxicity and variceal haemorrhage in children treated for acute lymphoblastic leukaemia - a dual-centre experience
-
Ravikumara M, Hill FG, Wilson DC, et al. 6-Thioguanine-related chronic hepatotoxicity and variceal haemorrhage in children treated for acute lymphoblastic leukaemia - a dual-centre experience. J Pediatr Gastroenterol Nutrition. 2006;42:535-538.
-
(2006)
J Pediatr Gastroenterol Nutrition
, vol.42
, pp. 535-538
-
-
Ravikumara, M.1
Hill, F.G.2
Wilson, D.C.3
-
25
-
-
34948824782
-
Nodular regenerative hyperplasia in patients with inflammatory bowel disease treated with azathioprine
-
Vernier-Massouille G, Cosnes J, Lemann M, et al. Nodular regenerative hyperplasia in patients with inflammatory bowel disease treated with azathioprine. Gut. 2007;56:1404-1409.
-
(2007)
Gut
, vol.56
, pp. 1404-1409
-
-
Vernier-Massouille, G.1
Cosnes, J.2
Lemann, M.3
-
26
-
-
4444259109
-
Glutathione S-transferase M1 polymorphism: A risk factor for hepatic venoocclusive disease in bone marrow transplantation
-
Srivastava A, Poonkuzhali B, Shaji RV, et al. Glutathione S-transferase M1 polymorphism: a risk factor for hepatic venoocclusive disease in bone marrow transplantation. Blood. 2004;104:1574-1577.
-
(2004)
Blood
, vol.104
, pp. 1574-1577
-
-
Srivastava, A.1
Poonkuzhali, B.2
Shaji, R.V.3
-
27
-
-
26444447579
-
Thiopurine therapies: Problems, complexities, and progress with monitoring thioguanine nucleotides
-
Duley JA, Florin TH. Thiopurine therapies: problems, complexities, and progress with monitoring thioguanine nucleotides. Ther Drug Monitor. 2005;27:647-654.
-
(2005)
Ther Drug Monitor
, vol.27
, pp. 647-654
-
-
Duley, J.A.1
Florin, T.H.2
-
28
-
-
0037305373
-
Differences in nucleotide hydrolysis contribute to the differences between erythrocyte 6-thioguanine nucleotide concentrations determined by two widely used methods
-
Shipkova M, Armstrong VW, Wieland E, et al. Differences in nucleotide hydrolysis contribute to the differences between erythrocyte 6-thioguanine nucleotide concentrations determined by two widely used methods. Clin Chem. 2003;49:260-268.
-
(2003)
Clin Chem
, vol.49
, pp. 260-268
-
-
Shipkova, M.1
Armstrong, V.W.2
Wieland, E.3
-
29
-
-
21844458213
-
A multicenter assessment of liver toxicity by MRI and biopsy in IBD patients on 6-thioguanine
-
Seiderer J, Zech CJ, Reinisch W, et al. A multicenter assessment of liver toxicity by MRI and biopsy in IBD patients on 6-thioguanine. J Hepatol. 2005;43:303-309.
-
(2005)
J Hepatol
, vol.43
, pp. 303-309
-
-
Seiderer, J.1
Zech, C.J.2
Reinisch, W.3
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