Nodular regenerative hyperplasia: Not all nodules are created equal

Hepatology

Volumn 44, Issue 1, 2006, Pages 7-14

  Reshamwala, Preeti A ^a,c   Kleiner, David E ^b   Heller, Theo ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c UNIVERSITY OF MARYLAND MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTITRYPSIN; AZATHIAPRINE; EOSIN; HEMATOXYLIN; IMMUNOSUPPRESSIVE AGENT; NOTCH1 RECEPTOR; THIOPURINE METHYLTRANSFERASE; TIOGUANINE; UNCLASSIFIED DRUG;

ANAMNESIS; ANTIPHOSPHOLIPID SYNDROME; AUTOPSY; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; DIFFERENTIAL DIAGNOSIS; DRUG HYPERSENSITIVITY; FAMILIAL DISEASE; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOSUPPRESSIVE TREATMENT; LIVER ATROPHY; LIVER BIOPSY; LIVER CIRRHOSIS; LIVER FIBROSIS; LIVER HYPERPLASIA; LIVER REGENERATION; LIVER TRANSPLANTATION; NODULAR REGENERATIVE HYPERPLASIA; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PORTAL HYPERTENSION; PORTOSYSTEMIC ANASTOMOSIS; PRIORITY JOURNAL; REVIEW; SYSTEMIC DISEASE; TOXIC OIL SYNDROME;

BIOPSY; DIAGNOSIS, DIFFERENTIAL; FOCAL NODULAR HYPERPLASIA; HUMANS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 33745878829     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.21258     Document Type: Review

References (46)

1. Wanless IR. Micronodular transformation (nodular regenerative hyperplasia) of the liver: a report of 64 cases among 2,500 autopsies and a new classification of benign hepatocellular nodules. HEPATOLOGY 1990;11:787-797.
2. Wanless IR, Peterson P, Das A, Boitnott JK, Moore GW, Bernier V. Hepatic vascular disease and portal hypertension in polycythemia vera and agnogenic myeloid metaplasia: a clinicopathological study of 145 patients examined at autopsy. HEPATOLOGY 1990;12:1166-1174.
3. Austin A, Campbell E, Lane P, Elias E. Nodular regenerative hyperplasia of the liver and coeliac disease: potential role of IgA anticardiolipin antibody. Gut 2004;53:1032-1034.
4. Wanless IR, SoIt LC, Kortan P, Deck JH, Gardiner GW, Prokipchuk EJ. Nodular regenerative hyperplasia of the liver associated with macroglobulinemia. A clue to the pathogenesis. Am J Med 1981;70:1203-1209.
5. Nakanuma Y, Ohta G, Sasaki K. Nodular regenerative hyperplasia of the liver associated with polyarteritis nodosa. Arch Pathol Lab Med 1984;108:133-135.
6. Reynolds WJ, Wanless IR. Nodular regenerative hyperplasia of the liver in a patient with rheumatoid vasculitis: a morphometric study suggesting a role for hepatic arteritis in the pathogenesis. J Rheumatol 1984;11:838-842.
7. Al-Mukhaizeem KA, Rosenberg A, Sherker AH. Nodular regenerative hyperplasia of the liver: an under-recognized cause of portal hypertension in hematological disorders. Am J Hematol 2004;75:225-230.
8. Breen DP, Marinaki AM, Arenas M, Hayes PC. Pharmacogenetic association with adverse drug reactions to azathioprine immunosuppressive therapy following liver transplantation. Liver Transpl 2005;11:826-833.
9. Arnott ID, Ghosh S. Portal hypertension in the presence of minimal liver damage in Crohn's disease on long-term azathioprine: possible endothelial cell injury. Eur J Gastroenterol Hepatol 2000;12:569-573.
10. Daniel F, Cadranel JF, Seksik P, Cazier A, Duong Van Huyen JP, Ziol M, et al. Azathioprine induced nodular regenerative hyperplasia in IBD patients. Gastroenterol Clin Biol 2005;29:600-603.
11. Ranstrom S. Miliary hepatocellular adenomatosis. Acta Pathol Microbiol Scand 1953;33:225-229.
12. Steiner PE. Nodular regenerative hyperplasia of the liver. Am J Pathol 1959;35:943-953.
13. Grazioli L, Alberti D, Olivetti L, Rigamonti W, Codazzi F, Matricardi L, et al. Congenital absence of portal vein with nodular regenerative hyperplasia of the liver. Eur Radiol 2000;10:820-825.
14. Trenschel GM, Schubert A, Dries V, Benz-Bohm G. Nodular regenerative hyperplasia of the liver: case report of a 13-year-old girl and review of the literature. Pediatr Radiol 2000;30:64-68.
15. Galdeano S, Drut R. Nodular regenerative hyperplasia of fetal liver: a report of two cases. Pediatr Pathol 1991;11:479-485.
16. Dumortier J, Boillot O, Chevallier M, Berger F, Potier P, Valette PJ, et al. Familial occurrence of nodular regenerative hyperplasia of the liver: a report on three families. Gut 1999;45:289-294.
17. Wanless IR, Godwin TA, Allen F, Feder A. Nodular regenerative hyperplasia of the liver in hematologic disorders: a possible response to obliterative portal venopathy. A morphometric study of nine cases with an hypothesis on the pathogenesis. Medicine (Baltimore) 1980;59:367-379.
18. Nakhleh RE, Snover DC. Use of alpha-1-antitrypsin staining in the diagnosis of nodular regenerative hyperplasia of the liver. Hum Pathol 1988;19:1048-1052.
19. Solis-Herruzo JA, Vidal JV, Colina F, Santalla F, Castellano G. Nodular regenerative hyperplasia of the liver associated with the toxic oil syndrome: report of five cases. HEPATOLOGY 1986;6:687-693.
20. Colina F, Pinedo F, Solis JA, Moreno D, Nevado M. Nodular regenerative hyperplasia of the liver in early histological stages of primary biliary cirrhosis. Gastroenterology 1992;102:1319-1324.
21. Nakanuma Y, Ohta G. Nodular hyperplasia of the liver in primary biliary cirrhosis of early histological stages. Am J Gastroenterol 1987;82:8-10.
22. Morla RM, Ramos-Casals M, Garcia-Carrasco M, Cervera R, Font J, Bruguera M, et al. Nodular regenerative hyperplasia of the liver and antiphospholipid antibodies: report of two cases and review of the literature. Lupus 1999;8:160-163.
23. Klein R, Goller S, Bianchi L. Nodular regenerative hyperplasia (NRH) of the liver-a manifestation of "organ-specific antiphospholipid syndrome"? Immunobiology 2003;207:51-57.
24. Croquelois A, Blindenbacher A, Terracciano L, Wang X, Langer I, Radtke F, et al. Inducible inactivation of Notchl causes nodular regenerative hyperplasia in mice. HEPATOLOGY 2005;41:487-496.
25. Arvanitaki M, Adler M. Nodular regenerative hyperplasia of the liver. A review of 14 cases. Hepatogastroemerology 2001;48:1425-1429.
26. Naber AH, Van Haelst U, Yap SH. Nodular regenerative hyperplasia of the liver: an important cause of portal hypertension in non-cirrhotic patients. J Hepatol 1991;12:94-99.
27. Ueno S, Tanabe G, Sueyoshi K, Yoshinaka H, Yamamoto S, Kurita K, et al. Hepatic hemodynamics in a patient with nodular regenerative hyperplasia. Am J Gastroenterol 1996;91:1012-1015.
28. Terminology of nodular hepatocellular lesions. International Working Party. HEPATOLOGY 1995;22:983-993.
29. Makhlouf HR, Abdul-Al HM, Goodman ZD. Diagnosis of focal nodular hyperplasia of the liver by needle biopsy. Hum Pathol 2005;36:1210-1216.
30. Wanless IR, Mawdsley C, Adams R. On the pathogenesis of focal nodular hyperplasia of the liver. HEPATOLOGY 1985;5:1194-1200.
31. Kondo F. Benign nodular hepatocellular lesions caused by abnormal hepatic circulation: etiological analysis and introduction of a new concept. J Gastroenterol Hepatol 2001;16:1319-1328.
32. Choi BY, Nguyen MH. The diagnosis and management of benign hepatic tumors. J Clin Gastroenterol 2005;39:401-412.
33. Nakanuma Y, Hoso M, Sasaki M, Terada T, Katayanagi K, Nonomura A, et al. Histopathology of the liver in non-cirrhotic portal hypertension of unknown aetiology. Histopathology 1996;28:195-204.
34. Lau DT, Kleiner DE, Park Y, Di Bisceglie AM, Hoofnagle JH. Resolution of chronic delta hepatitis after 12 years of Interferon alfa therapy. Gastroenterology 1999;117:1229-1233.
35. Banares R, Albillos A, Rincon D, Alonso S, Gonzalez M, Ruiz-del-Arbol L, et al. Endoscopic treatment versus endoscopic plus pharmacologic treatment for acute variceal bleeding: a meta-analysis. HEPATOLOGY 2002;35:609-615.
36. D'Amico G, Pagliaro L, Bosch J. Pharmacological treatment of portal hypertension: an evidence-based approach. Semin Liver Dis 1999;19:475-505.
37. Abraldes JG, Bosch J. Somatostatin and analogues in portal hypertension. HEPATOLOGY 2002;35:1305-1312.
38. Grace ND. Diagnosis and treatment of gastrointestinal bleeding secondary to portal hypertension. American College of Gastroenterology Practice Parameters Committee. Am J Gastroenterol 1997;92:1081-1091.
39. Krasinskas AM, Eghtesad B, Kamath PS, Demetris AJ, Abraham SC. Liver transplantation for severe intrahepatic noncirrhotic portal hypertension. Liver Transpl 2005;11:627-634 [discussion:610-621].
40. Loinaz C, Colina F, Musella M, Lopez-Rios F, Gomez R, Jimenez C, et al. Orthotopic liver transplantation in 4 patients with portal hypertension and non-cirrhotic nodular liver. Hepatogastroenterology 1998;45:1787-1794.
41. Kobayashi S, Saito K, Nakanuma Y. Nodular regenerative hyperplasia of the liver in hepatocellular carcinoma. An autopsy study. J Clin Gastroenterol 1993;16:155-159.
42. Russmann S, Zimmermann A, Krahenbuhl S, Kern B, Reichen J. Veno-occlusive disease, nodular regenerative hyperplasia and hepatocellular carcinoma after azathioprine treatment in a patient with ulcerative colitis. Eur J Gastroenterol Hepatol 2001;13:287-290.
43. Nzeako UC, Goodman ZD, Ishak KG. Hepatocellular carcinoma and nodular regenerative hyperplasia: possible pathogenetic relationship. Am J Gastroenterol 1996;91:879-884.
44. Mulcahy MF. Management of hepatocellular cancer. Curr Treat Options Oncol 2005;6:423-435.
45. Beaugrand M, N'Kontchou G, Seror O, Ganne N, Trinchet JC. Local/ regional and systemic treatments of hepatocellular carcinoma. Semin Liver Dis 2005;25:201-211.
46. Llovet JM, Fuster J, Bruix J. The Barcelona approach: diagnosis, staging, and treatment of hepatocellular carcinoma. Liver Transpl 2004;10:S115-S120.