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Volumn 73, Issue 1, 2006, Pages 25-31

6-Thioguanine treatment in inflammatory bowel disease: A critical appraisal by a European 6-TG working party

Author keywords

6 Thioguanine; Crohn's disease and ulcerative colitis; Inflammatory bowel disease; Thiopurine

Indexed keywords

AMINOSALICYLIC ACID; AZATHIOPRINE; INFLIXIMAB; MERCAPTOPURINE; METHOTREXATE; TIOGUANINE;

EID: 33744490627     PISSN: 00122823     EISSN: None     Source Type: Journal    
DOI: 10.1159/000091662     Document Type: Conference Paper
Times cited : (63)

References (48)
  • 1
    • 4344602852 scopus 로고    scopus 로고
    • Guidelines for the management of inflammatory bowel disease in adults
    • Carter MJ, Lobo AJ, Travis SP: Guidelines for the management of inflammatory bowel disease in adults. Gut 2004;53(suppl 5):V1-V16.
    • (2004) Gut , vol.53 , Issue.5 SUPPL.
    • Carter, M.J.1    Lobo, A.J.2    Travis, S.P.3
  • 4
    • 2442560241 scopus 로고    scopus 로고
    • Optimizing anti-TNF treatment in inflammatory bowel disease
    • Rutgeerts P, Van Assche G, Vermeire S: Optimizing anti-TNF treatment in inflammatory bowel disease. Gastroenterology 2004;126:1593-1610.
    • (2004) Gastroenterology , vol.126 , pp. 1593-1610
    • Rutgeerts, P.1    Van Assche, G.2    Vermeire, S.3
  • 5
    • 23044499897 scopus 로고    scopus 로고
    • Thiopurines in inflammatory bowel disease: Pharmacogenetics, therapeutic drug monitoring and clinical recommendations
    • Al Hadithy AF, de Boer NK, Derijks LJ, Escher JC, Mulder CJ, Brouwers JR: Thiopurines in inflammatory bowel disease: pharmacogenetics, therapeutic drug monitoring and clinical recommendations. Dig Liver Dis 2005;37:282-297.
    • (2005) Dig Liver Dis , vol.37 , pp. 282-297
    • Al Hadithy, A.F.1    De Boer, N.K.2    Derijks, L.J.3    Escher, J.C.4    Mulder, C.J.5    Brouwers, J.R.6
  • 6
    • 27644554667 scopus 로고    scopus 로고
    • Randomised, controlled trial, of azathioprine and 5-aminosalicylic acid for treatment of steroid-dependent ulcerative colitis
    • in press
    • Ardizzone S, Maconi G, Russo A, Imbesi V, Colombo E, Bianchi PG: Randomised, controlled trial, of azathioprine and 5-aminosalicylic acid for treatment of steroid-dependent ulcerative colitis. Gut 2005; in press.
    • (2005) Gut
    • Ardizzone, S.1    Maconi, G.2    Russo, A.3    Imbesi, V.4    Colombo, E.5    Bianchi, P.G.6
  • 9
    • 0035183727 scopus 로고    scopus 로고
    • Why measure thiopurine methyltransferase activity? Direct administration of 6-thioguanine might be the alternative for 6-mercaptopurine or azathioprine
    • de Jong D, Mulder CJ, van Sorge AA: Why measure thiopurine methyltransferase activity? Direct administration of 6-thioguanine might be the alternative for 6-mercaptopurine or azathioprine. Gut 2001;49:874.
    • (2001) Gut , vol.49 , pp. 874
    • De Jong, D.1    Mulder, C.J.2    Van Sorge, A.A.3
  • 11
    • 0035423158 scopus 로고    scopus 로고
    • Differing contribution of thiopurine methyltransferase to mercaptopurine versus thioguanine effects in human leukemic cells
    • Dervieux T, Blanco JG, Krynetski EY, Vanin EF, Roussel MF, Relling MV: Differing contribution of thiopurine methyltransferase to mercaptopurine versus thioguanine effects in human leukemic cells. Cancer Res 2001;61:5810-5816.
    • (2001) Cancer Res , vol.61 , pp. 5810-5816
    • Dervieux, T.1    Blanco, J.G.2    Krynetski, E.Y.3    Vanin, E.F.4    Roussel, M.F.5    Relling, M.V.6
  • 13
    • 3242762099 scopus 로고    scopus 로고
    • Comprehensive analysis of thiopurine S-methyltransferase phenotype-genotype correlation in a large population of German-Caucasians and identification of novel TPMT variants
    • Schaeffeler E, Fischer C, Brockmeier D, Wernet D, Moerike K, Eichelbaum M, Zanger UM, Schwab M: Comprehensive analysis of thiopurine S-methyltransferase phenotype-genotype correlation in a large population of German-Caucasians and identification of novel TPMT variants. Pharmacogenetics 2004;14:407-417.
    • (2004) Pharmacogenetics , vol.14 , pp. 407-417
    • Schaeffeler, E.1    Fischer, C.2    Brockmeier, D.3    Wernet, D.4    Moerike, K.5    Eichelbaum, M.6    Zanger, U.M.7    Schwab, M.8
  • 15
    • 0034263837 scopus 로고    scopus 로고
    • Severe 6-thioguanine-induced marrow aplasia in a child with acute lymphoblastic leukemia and inherited thiopurine methyltransferase deficiency
    • McBride KL, Gilchrist GS, Smithson WA, Weinshilboum RM, Szumlanski CL: Severe 6-thioguanine-induced marrow aplasia in a child with acute lymphoblastic leukemia and inherited thiopurine methyltransferase deficiency. J Pediatr Hematol Oncol 2000;22:441-445.
    • (2000) J Pediatr Hematol Oncol , vol.22 , pp. 441-445
    • McBride, K.L.1    Gilchrist, G.S.2    Smithson, W.A.3    Weinshilboum, R.M.4    Szumlanski, C.L.5
  • 18
    • 9244237558 scopus 로고    scopus 로고
    • Lack of association between the ITPA 94C>A polymorphism and adverse effects from azathioprine
    • Gearry RB, Roberts RL, Barclay ML, Kennedy MA: Lack of association between the ITPA 94C>A polymorphism and adverse effects from azathioprine. Pharmacogenetics 2004;14:779-781.
    • (2004) Pharmacogenetics , vol.14 , pp. 779-781
    • Gearry, R.B.1    Roberts, R.L.2    Barclay, M.L.3    Kennedy, M.A.4
  • 19
    • 27444437058 scopus 로고    scopus 로고
    • ITPA genotyping is not predictive for the development of side effects in AZA treated inflammatory bowel disease patients
    • van Dieren JM, van Vuuren AJ, Kusters JG, Nieuwenhuis EE, Kuipers EJ, van der Woude CJ: ITPA genotyping is not predictive for the development of side effects in AZA treated inflammatory bowel disease patients. Gut 2005;54:1664.
    • (2005) Gut , vol.54 , pp. 1664
    • Van Dieren, J.M.1    Van Vuuren, A.J.2    Kusters, J.G.3    Nieuwenhuis, E.E.4    Kuipers, E.J.5    Van Der Woude, C.J.6
  • 20
    • 0001647780 scopus 로고
    • Treatment of ulcerative colitis with antimetabolites
    • Bean, RHD: Treatment of ulcerative colitis with antimetabolites. Br Med J 1966;1:1081-1084.
    • (1966) Br Med J , vol.1 , pp. 1081-1084
    • Bean, R.H.D.1
  • 21
    • 0034891450 scopus 로고    scopus 로고
    • An open-label pilot study using thioguanine as a therapeutic alternative in Crohn's disease patients resistant to 6-mercaptopurine therapy
    • Dubinsky MC, Hassard PV, Seidman EG, Kam LY, Abreu MT, Targan SR, Vasiliauskas EA: An open-label pilot study using thioguanine as a therapeutic alternative in Crohn's disease patients resistant to 6-mercaptopurine therapy. Inflamm Bowel Dis 2001;7:181-189.
    • (2001) Inflamm Bowel Dis , vol.7 , pp. 181-189
    • Dubinsky, M.C.1    Hassard, P.V.2    Seidman, E.G.3    Kam, L.Y.4    Abreu, M.T.5    Targan, S.R.6    Vasiliauskas, E.A.7
  • 25
  • 26
    • 0038805258 scopus 로고    scopus 로고
    • Thioguanine: A potential alternate tniopurine for IBD patients allergic to 6-mercaptopurine or azathioprine
    • Dubinsky MC, Feldman EJ, Abreu MT, Targan SR, Vasiliauskas EA: Thioguanine: a potential alternate tniopurine for IBD patients allergic to 6-mercaptopurine or azathioprine. Am J Gastroenterol 2003;98:1058-1063.
    • (2003) Am J Gastroenterol , vol.98 , pp. 1058-1063
    • Dubinsky, M.C.1    Feldman, E.J.2    Abreu, M.T.3    Targan, S.R.4    Vasiliauskas, E.A.5
  • 28
    • 24944497803 scopus 로고    scopus 로고
    • Long-term efficacy of 6-thioguanine in patients with inflammatory bowel disease
    • Teml A, Dejaco C, Miehsler W, Harrer M, Vogelsang H, Reinisch W: Long-term efficacy of 6-thioguanine in patients with inflammatory bowel disease. Gut 2005;53(suppl VI):A229.
    • (2005) Gut , vol.53 , Issue.6 SUPPL.
    • Teml, A.1    Dejaco, C.2    Miehsler, W.3    Harrer, M.4    Vogelsang, H.5    Reinisch, W.6
  • 32
    • 0035090185 scopus 로고    scopus 로고
    • Veno-occlusive disease, nodular regenerative hyperplasia and hepatocellular carcinoma after azathioprine treatment in a patient with ulcerative colitis
    • Russmann S, Zimmemiann A, Krahenbuhl S, Kern B, Reichen J: Veno-occlusive disease, nodular regenerative hyperplasia and hepatocellular carcinoma after azathioprine treatment in a patient with ulcerative colitis. Eur J Gastroenterol Hepatol 2001;13:287-290.
    • (2001) Eur J Gastroenterol Hepatol , vol.13 , pp. 287-290
    • Russmann, S.1    Zimmemiann, A.2    Krahenbuhl, S.3    Kern, B.4    Reichen, J.5
  • 33
    • 0026007703 scopus 로고
    • Nodular regenerative hyperplasia of the liver: An important cause of portal hypertension in non-cirrhotic patients
    • Naber AH, Van Haelst U, Yap SH: Nodular regenerative hyperplasia of the liver: an important cause of portal hypertension in non-cirrhotic patients. J Hepatol 1991;12:94-99.
    • (1991) J Hepatol , vol.12 , pp. 94-99
    • Naber, A.H.1    Van Haelst, U.2    Yap, S.H.3
  • 35
    • 0023689209 scopus 로고
    • Is nodular regenerative hyperplasia of the liver associated with azathioprine therapy after renal transplantation?
    • Jones MC, Best PV, Catto GR: Is nodular regenerative hyperplasia of the liver associated with azathioprine therapy after renal transplantation? Nephrol Dial Transplant 1988;3:331-333.
    • (1988) Nephrol Dial Transplant , vol.3 , pp. 331-333
    • Jones, M.C.1    Best, P.V.2    Catto, G.R.3
  • 36
    • 0023896137 scopus 로고
    • Role of endothelial cell injury in the spectrum of azathioprine-induced liver disease after renal transplant: Light microscopy and ultrastructural observations
    • Haboubi NY, Ali HH, Whitwell HL, Ackrill P: Role of endothelial cell injury in the spectrum of azathioprine-induced liver disease after renal transplant: light microscopy and ultrastructural observations. Am J Gastroenterol 1988;83:256-261.
    • (1988) Am J Gastroenterol , vol.83 , pp. 256-261
    • Haboubi, N.Y.1    Ali, H.H.2    Whitwell, H.L.3    Ackrill, P.4
  • 37
    • 0024212041 scopus 로고
    • Portal hypertension secondary to azathioprine in myasthenia gravis
    • Fonseca V, Havard CW: Portal hypertension secondary to azathioprine in myasthenia gravis. Postgrad Med J 1988;64:950-952.
    • (1988) Postgrad Med J , vol.64 , pp. 950-952
    • Fonseca, V.1    Havard, C.W.2
  • 38
    • 0028233357 scopus 로고
    • Nodular regenerative hyperplasia of the liver graft after liver transplantation
    • Gane E, Portmann B, Saxena R, Wong P, Ramage J, Williams R: Nodular regenerative hyperplasia of the liver graft after liver transplantation. Hepatology 1994;20:88-94.
    • (1994) Hepatology , vol.20 , pp. 88-94
    • Gane, E.1    Portmann, B.2    Saxena, R.3    Wong, P.4    Ramage, J.5    Williams, R.6
  • 39
    • 0346998117 scopus 로고    scopus 로고
    • Early nodular hyperplasia of the liver occurring with inflammatory bowel diseases in association with thioguanine therapy
    • Shastri S, Dubinsky MC, Fred PF, Vasiliauskas EA, Geller SA: Early nodular hyperplasia of the liver occurring with inflammatory bowel diseases in association with thioguanine therapy. Arch Pathol Lab Med 2004;128:49-53.
    • (2004) Arch Pathol Lab Med , vol.128 , pp. 49-53
    • Shastri, S.1    Dubinsky, M.C.2    Fred, P.F.3    Vasiliauskas, E.A.4    Geller, S.A.5
  • 41
    • 33744469245 scopus 로고    scopus 로고
    • 6-thioguanine associated nodular regenerative hyperplasia in patients with inflammatory bowel disease may induce portal hypertension
    • Ferlitsch A, Teml A, Reinisch W, Peck-Radosavljevic M, Wrba F, Ulbrich G, Vogelsang H: 6-thioguanine associated nodular regenerative hyperplasia in patients with inflammatory bowel disease may induce portal hypertension. Gut 2005;54(suppl VII):A45.
    • (2005) Gut , vol.54 , Issue.7 SUPPL.
    • Ferlitsch, A.1    Teml, A.2    Reinisch, W.3    Peck-Radosavljevic, M.4    Wrba, F.5    Ulbrich, G.6    Vogelsang, H.7
  • 42
    • 27244452424 scopus 로고    scopus 로고
    • Nodular regenerative hyperplasia and thiopurines: The case for level-dependent toxicity
    • de Boer NK, Mulder CJ, van Bodegraven AA: Nodular regenerative hyperplasia and thiopurines: the case for level-dependent toxicity. Liver Transpl 2005;11:1300-1301.
    • (2005) Liver Transpl , vol.11 , pp. 1300-1301
    • De Boer, N.K.1    Mulder, C.J.2    Van Bodegraven, A.A.3
  • 46
    • 0017650140 scopus 로고
    • Consequences of acute myelogenous leukemia in early pregnancy
    • Lilleyman JS, Hill AS, Anderton KJ: Consequences of acute myelogenous leukemia in early pregnancy. Cancer 1977;40:1300-1303.
    • (1977) Cancer , vol.40 , pp. 1300-1303
    • Lilleyman, J.S.1    Hill, A.S.2    Anderton, K.J.3
  • 47
    • 0028343407 scopus 로고
    • Teratogenic effects in a case of maternal treatment for acute myelocytic leukaemia: Neonatal and infantile course
    • Artlich A, Moller J, Tschakaloff A, Schwinger E, Kruse K, Gortner L: Teratogenic effects in a case of maternal treatment for acute myelocytic leukaemia: neonatal and infantile course. Eur J Pediatr 1994;153:488-491.
    • (1994) Eur J Pediatr , vol.153 , pp. 488-491
    • Artlich, A.1    Moller, J.2    Tschakaloff, A.3    Schwinger, E.4    Kruse, K.5    Gortner, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.