-
1
-
-
4544239107
-
Thiopurine drug adverse effects in a population of New Zealand patients with inflammatory bowel disease
-
Gearry RB, Barclay ML, Burt MJ, et al. Thiopurine drug adverse effects in a population of New Zealand patients with inflammatory bowel disease. Pharmacoepidemiol Drug Saf 2004 13 : 563 7.
-
(2004)
Pharmacoepidemiol Drug Saf
, vol.13
, pp. 563-7
-
-
Gearry, R.B.1
Barclay, M.L.2
Burt, M.J.3
-
2
-
-
0036278519
-
The efficacy of azathioprine for the treatment of inflammatory bowel disease: A 30-year review
-
Fraser AG, Orchard TR, Jewell DP. The efficacy of azathioprine for the treatment of inflammatory bowel disease: A 30-year review. Gut 2002 50 : 485 9.
-
(2002)
Gut
, vol.50
, pp. 485-9
-
-
Fraser, A.G.1
Orchard, T.R.2
Jewell, D.P.3
-
3
-
-
33947287144
-
Thiopurine treatment in inflammatory bowel disease: Clinical pharmacology and implication of pharmacogenetically guided dosing
-
Teml A, Schaeffeler E, Herrlinger KR, et al. Thiopurine treatment in inflammatory bowel disease: Clinical pharmacology and implication of pharmacogenetically guided dosing. Clin Pharmacokinet 2007 46 : 187 208.
-
(2007)
Clin Pharmacokinet
, vol.46
, pp. 187-208
-
-
Teml, A.1
Schaeffeler, E.2
Herrlinger, K.R.3
-
4
-
-
33144459948
-
European evidence based consensus on the diagnosis and management of Crohn's disease: Current management
-
European Crohn's and Colitis Organisation.
-
Travis SP, Stange EF, Lemann M, et al. European Crohn's and Colitis Organisation. European evidence based consensus on the diagnosis and management of Crohn's disease: Current management. Gut 2006 55 (Suppl 1 i16-35.
-
(2006)
Gut
, vol.55
, Issue.1
-
-
Travis, S.P.1
Stange, E.F.2
Lemann, M.3
-
5
-
-
0023022265
-
Historical background of 6-mercaptopurine
-
Elion GB. Historical background of 6-mercaptopurine. Toxicol Ind Health 1986 2 : 1 9.
-
(1986)
Toxicol Ind Health
, vol.2
, pp. 1-9
-
-
Elion, G.B.1
-
6
-
-
0027276221
-
Is 6-TG more appropriate than 6-mercaptopurine for children with acute lymphoblastic leukaemia?
-
Lennard L, Davies HA, Lilleyman JS. Is 6-TG more appropriate than 6-mercaptopurine for children with acute lymphoblastic leukaemia? Br J Cancer 1993 68 : 186 90.
-
(1993)
Br J Cancer
, vol.68
, pp. 186-90
-
-
Lennard, L.1
Davies, H.A.2
Lilleyman, J.S.3
-
7
-
-
0034891450
-
An open-label pilot study using thioguanine as a therapeutic alternative in Crohn's disease patients resistant to 6-mercaptopurine therapy
-
Dubinsky MC, Hassard PV, Seidman EG, et al. An open-label pilot study using thioguanine as a therapeutic alternative in Crohn's disease patients resistant to 6-mercaptopurine therapy. Inflamm Bowel Dis 2001 7 : 181 9.
-
(2001)
Inflamm Bowel Dis
, vol.7
, pp. 181-9
-
-
Dubinsky, M.C.1
Hassard, P.V.2
Seidman, E.G.3
-
8
-
-
0038805258
-
Thioguanine: A potential alternate thiopurine for IBD patients allergic to 6-mercaptopurine or azathioprine
-
Dubinsky MC, Feldman EJ, Abreu MT, et al. Thioguanine: A potential alternate thiopurine for IBD patients allergic to 6-mercaptopurine or azathioprine. Am J Gastroenterol 2003 98 : 1058 63.
-
(2003)
Am J Gastroenterol
, vol.98
, pp. 1058-63
-
-
Dubinsky, M.C.1
Feldman, E.J.2
Abreu, M.T.3
-
9
-
-
0038235691
-
Remission maintenance by tioguanine in chronic active Crohn's disease
-
Herrlinger KR, Deibert P, Schwab M, et al. Remission maintenance by tioguanine in chronic active Crohn's disease. Aliment Pharmacol Ther 2003 17 : 1459 64.
-
(2003)
Aliment Pharmacol Ther
, vol.17
, pp. 1459-64
-
-
Herrlinger, K.R.1
Deibert, P.2
Schwab, M.3
-
10
-
-
0042629433
-
High variation of tioguanine absorption in patients with chronic active Crohn's disease
-
Deibert P, Dilger K, Fischer C, et al. High variation of tioguanine absorption in patients with chronic active Crohn's disease. Aliment Pharmacol Ther 2003 18 : 183 9.
-
(2003)
Aliment Pharmacol Ther
, vol.18
, pp. 183-9
-
-
Deibert, P.1
Dilger, K.2
Fischer, C.3
-
11
-
-
0041327800
-
Tioguanine in patients with Crohn's disease intolerant or resistant to azathioprine/mercaptopurine
-
Getaid.
-
Bonaz B, Boitard J, Marteau P, et al Getaid. Tioguanine in patients with Crohn's disease intolerant or resistant to azathioprine/mercaptopurine. Aliment Pharmacol Ther 2003 18 : 401 8.
-
(2003)
Aliment Pharmacol Ther
, vol.18
, pp. 401-8
-
-
Bonaz, B.1
Boitard, J.2
Marteau, P.3
Al, E.4
-
12
-
-
0037250161
-
6-Thioguanine seems promising in azathioprine- or 6-mercaptopurine- intolerant inflammatory bowel disease patients: A short-term safety assessment
-
Derijks LJ, de Jong DJ, Gilissen LP, et al. 6-Thioguanine seems promising in azathioprine- or 6-mercaptopurine-intolerant inflammatory bowel disease patients: A short-term safety assessment. Eur J Gastroenterol Hepatol 2003 15 : 63 7.
-
(2003)
Eur J Gastroenterol Hepatol
, vol.15
, pp. 63-7
-
-
Derijks, L.J.1
De Jong, D.J.2
Gilissen, L.P.3
-
13
-
-
0037285921
-
6-Thioguanine: A new old drug to procure remission in inflammatory bowel disease
-
Cheung TK, Florin TH. 6-Thioguanine: A new old drug to procure remission in inflammatory bowel disease. Intern Med J 2003 33 : 44 6.
-
(2003)
Intern Med J
, vol.33
, pp. 44-6
-
-
Cheung, T.K.1
Florin, T.H.2
-
14
-
-
27144448052
-
A prospective, open-label trial of 6-thioguanine in patients with ulcerative or indeterminate colitis
-
Teml A, Schwab M, Harrer M, et al. A prospective, open-label trial of 6-thioguanine in patients with ulcerative or indeterminate colitis. Scand J Gastroenterol 2005 40 : 1205 13.
-
(2005)
Scand J Gastroenterol
, vol.40
, pp. 1205-13
-
-
Teml, A.1
Schwab, M.2
Harrer, M.3
-
15
-
-
0043168014
-
6-Thioguanine can cause serious liver injuries in inflammatory bowel disease patients
-
Dubinsky MC, Vasiliaukas EA, Singh H, et al. 6-Thioguanine can cause serious liver injuries in inflammatory bowel disease patients. Gastroenterology 2003 125 : 298 303.
-
(2003)
Gastroenterology
, vol.125
, pp. 298-303
-
-
Dubinsky, M.C.1
Vasiliaukas, E.A.2
Singh, H.3
-
16
-
-
21844458213
-
A multicenter assessment of liver toxicity by MRI and biopsy in IBD patients on 6-thioguanine
-
Seiderer J, Zech CJ, Reinisch W, et al. A multicenter assessment of liver toxicity by MRI and biopsy in IBD patients on 6-thioguanine. J Hepatol 2005 43 : 303 9.
-
(2005)
J Hepatol
, vol.43
, pp. 303-9
-
-
Seiderer, J.1
Zech, C.J.2
Reinisch, W.3
-
17
-
-
4344583899
-
Early hepatic nodular hyperplasia and submicroscopic fibrosis associated with 6-thioguanine therapy in inflammatory bowel disease
-
Geller SA, Dubinsky MC, Poordad FF, et al. Early hepatic nodular hyperplasia and submicroscopic fibrosis associated with 6-thioguanine therapy in inflammatory bowel disease. Am J Surg Pathol 2004 28 : 1204 11.
-
(2004)
Am J Surg Pathol
, vol.28
, pp. 1204-11
-
-
Geller, S.A.1
Dubinsky, M.C.2
Poordad, F.F.3
-
18
-
-
35448999022
-
A systematic survey evaluating 6-TG-related hepatotoxicity in patients with IBD
-
Teml A, Schwab M, Hommes DW, et al. A systematic survey evaluating 6-TG-related hepatotoxicity in patients with IBD. Clin Pharmacol Ther 2006 44 : 503.
-
(2006)
Clin Pharmacol Ther
, vol.44
, pp. 503
-
-
Teml, A.1
Schwab, M.2
Hommes, D.W.3
-
19
-
-
0037370693
-
Hepatotoxicity associated with 6-thioguanine therapy for Crohn's disease
-
Rulyak SJ, Saunders MD, Lee SD. Hepatotoxicity associated with 6-thioguanine therapy for Crohn's disease. J Clin Gastroenterol 2003 36 : 234 7.
-
(2003)
J Clin Gastroenterol
, vol.36
, pp. 234-7
-
-
Rulyak, S.J.1
Saunders, M.D.2
Lee, S.D.3
-
20
-
-
0035090185
-
Veno-occlusive disease, nodular regenerative hyperplasia and hepatocellular carcinoma after azathioprine treatment in a patient with ulcerative colitis
-
Russmann S, Zimmermann A, Krahenbuhl S, et al. Veno-occlusive disease, nodular regenerative hyperplasia and hepatocellular carcinoma after azathioprine treatment in a patient with ulcerative colitis. Eur J Gastroenterol Hepatol 2001 13 : 287 90.
-
(2001)
Eur J Gastroenterol Hepatol
, vol.13
, pp. 287-90
-
-
Russmann, S.1
Zimmermann, A.2
Krahenbuhl, S.3
-
21
-
-
20444472032
-
Azathioprine-induced nodular regenerative hyperplasia in IBD patients
-
Daniel F, Cadranel JF, Seksik P, et al. Azathioprine-induced nodular regenerative hyperplasia in IBD patients. Gastroenterol Clin Biol 2005 29 : 600 3.
-
(2005)
Gastroenterol Clin Biol
, vol.29
, pp. 600-3
-
-
Daniel, F.1
Cadranel, J.F.2
Seksik, P.3
-
22
-
-
0037216917
-
Nodular regenerative hyperplasia (NRH) of the liver - A manifestation of "organ-specific antiphospholipid syndrome"?
-
Klein R, Goller S, Bianchi L. Nodular regenerative hyperplasia (NRH) of the liver - a manifestation of "organ-specific antiphospholipid syndrome"? Immunobiology 2003 207 : 51 7.
-
(2003)
Immunobiology
, vol.207
, pp. 51-7
-
-
Klein, R.1
Goller, S.2
Bianchi, L.3
-
23
-
-
0034781491
-
Nodular regenerative hyperplasia of the liver. a review of 14 cases
-
Arvanitaki M, Adler M. Nodular regenerative hyperplasia of the liver. A review of 14 cases. Hepatogastroenterology 2001 48 : 1425 9.
-
(2001)
Hepatogastroenterology
, vol.48
, pp. 1425-9
-
-
Arvanitaki, M.1
Adler, M.2
-
24
-
-
0033922728
-
Liver nodular regenerative hyperplasia after bone marrow transplant
-
Pezzullo L, Muretto P, De Rosa G, et al. Liver nodular regenerative hyperplasia after bone marrow transplant. Haematologica 2000 85 : 669 70.
-
(2000)
Haematologica
, vol.85
, pp. 669-70
-
-
Pezzullo, L.1
Muretto, P.2
De Rosa, G.3
-
25
-
-
0036786372
-
Nodular regenerative hyperplasia in a rheumatoid arthritis patient without felty's syndrome
-
Goritsas C, Roussos A, Ferti A, et al. Nodular regenerative hyperplasia in a rheumatoid arthritis patient without felty's syndrome. J Clin Gastroenterol 2002 35 : 363 4.
-
(2002)
J Clin Gastroenterol
, vol.35
, pp. 363-4
-
-
Goritsas, C.1
Roussos, A.2
Ferti, A.3
-
26
-
-
0025303034
-
Micronodular transformation (nodular regenerative hyperplasia) of the liver: A report of 64 cases among 2,500 autopsies and a new classification of benign hepatocellular nodules
-
Wanless IR. Micronodular transformation (nodular regenerative hyperplasia) of the liver: A report of 64 cases among 2,500 autopsies and a new classification of benign hepatocellular nodules. Hepatology 1990 11 : 787 97.
-
(1990)
Hepatology
, vol.11
, pp. 787-97
-
-
Wanless, I.R.1
-
27
-
-
0018954819
-
Nodular regenerative hyperplasia of the liver in haematologic disorders: A possible response to obliterative portal venopathy
-
Wanless IR, Godwin TA, Allen F, et al. Nodular regenerative hyperplasia of the liver in haematologic disorders: A possible response to obliterative portal venopathy. Medicine 1980 59 : 367 79.
-
(1980)
Medicine
, vol.59
, pp. 367-79
-
-
Wanless, I.R.1
Godwin, T.A.2
Allen, F.3
-
28
-
-
21044444754
-
Liver transplantation for severe intrahepatic noncirrhotic portal hypertension
-
Krasinskas AM, Eghtesad B, Kamath PS, et al. Liver transplantation for severe intrahepatic noncirrhotic portal hypertension. Liver Transpl 2005 11 : 627 34.
-
(2005)
Liver Transpl
, vol.11
, pp. 627-34
-
-
Krasinskas, A.M.1
Eghtesad, B.2
Kamath, P.S.3
-
29
-
-
0023637864
-
Oesophageal varices associated with busulphan-thioguanine combination therapy for chronic myeloid leukaemia
-
Key NS, Kelly PM, Emerson PM, et al. Oesophageal varices associated with busulphan-thioguanine combination therapy for chronic myeloid leukaemia. Lancet 1987 2 : 1050 2.
-
(1987)
Lancet
, vol.2
, pp. 1050-2
-
-
Key, N.S.1
Kelly, P.M.2
Emerson, P.M.3
-
30
-
-
33744495734
-
6-Thioguanine-related chronic hepatotoxicity and variceal haemorrhage in children treated for acute lymphoblastic leukaemia: A dual-centre experience
-
Ravikumara M, Hill FG, Wilson DC, et al. 6-Thioguanine-related chronic hepatotoxicity and variceal haemorrhage in children treated for acute lymphoblastic leukaemia: A dual-centre experience. J Pediatr Gastroenterol Nutr 2006 42 : 535 8.
-
(2006)
J Pediatr Gastroenterol Nutr
, vol.42
, pp. 535-8
-
-
Ravikumara, M.1
Hill, F.G.2
Wilson, D.C.3
-
31
-
-
13444270315
-
Portal hypertension develops in a subset of children with standard risk acute lymphoblastic leukemia treated with oral 6-thioguanine during maintenance therapy
-
Broxson EH, Dole M, Wong R, et al. Portal hypertension develops in a subset of children with standard risk acute lymphoblastic leukemia treated with oral 6-thioguanine during maintenance therapy. Pediatr Blood Cancer 2005 44 : 226 31.
-
(2005)
Pediatr Blood Cancer
, vol.44
, pp. 226-31
-
-
Broxson, E.H.1
Dole, M.2
Wong, R.3
-
32
-
-
0026056297
-
Thioguanine used in maintenance therapy for chronic myeloid leukemia causes non-cirrhotic portal hypertension
-
Shepherd PCA, Fooks J, Gray R, et al. Thioguanine used in maintenance therapy for chronic myeloid leukemia causes non-cirrhotic portal hypertension. Br J Haematol 1991 79 : 185 92.
-
(1991)
Br J Haematol
, vol.79
, pp. 185-92
-
-
Shepherd, P.C.A.1
Fooks, J.2
Gray, R.3
-
33
-
-
30344466643
-
Chronic liver disease related to 6-thioguanine in children with acute lymphoblastic leukaemia
-
De Bruyne R, Portmann B, Samyn M, et al. Chronic liver disease related to 6-thioguanine in children with acute lymphoblastic leukaemia. J Hepatol 2006 44 : 407 10.
-
(2006)
J Hepatol
, vol.44
, pp. 407-10
-
-
De Bruyne, R.1
Portmann, B.2
Samyn, M.3
-
34
-
-
2442426385
-
Chronic hepatotoxicity following 6-thioguanine therapy for childhood acute lymphoblastic leukaemia
-
Piel B, Vaidya S, Lancaster D, et al. Chronic hepatotoxicity following 6-thioguanine therapy for childhood acute lymphoblastic leukaemia. Br J Haematol 2004 125 : 410 1.
-
(2004)
Br J Haematol
, vol.125
, pp. 410-1
-
-
Piel, B.1
Vaidya, S.2
Lancaster, D.3
-
35
-
-
33744490627
-
6-Thioguanine treatment in inflammatory bowel disease: A critical appraisal by a European 6-TG working party
-
de Boer NK, Reinisch W, Teml A, et al. 6-Thioguanine treatment in inflammatory bowel disease: A critical appraisal by a European 6-TG working party. Digestion 2006 73 : 25 31.
-
(2006)
Digestion
, vol.73
, pp. 25-31
-
-
De Boer, N.K.1
Reinisch, W.2
Teml, A.3
-
36
-
-
84894353884
-
Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology
-
Silverberg MS, Satsangi J, Ahmad T, et al. Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology. Can J Gastroenterol 2005 19 (Suppl A 5 36.
-
(2005)
Can J Gastroenterol
, vol.19
, pp. 5-36
-
-
Silverberg, M.S.1
Satsangi, J.2
Ahmad, T.3
-
38
-
-
34248664736
-
Transient elastography for diagnosis of portal hypertension in liver cirrhosis: Is there still a role for hepatic venous pressure gradient measurement?
-
Lim JK, Groszmann RJ. Transient elastography for diagnosis of portal hypertension in liver cirrhosis: Is there still a role for hepatic venous pressure gradient measurement? Hepatology 2007 45 : 1087 90.
-
(2007)
Hepatology
, vol.45
, pp. 1087-90
-
-
Lim, J.K.1
Groszmann, R.J.2
-
39
-
-
21644441429
-
Austrian consensus on the definition and treatment of portal hypertension and its complications
-
Peck-Radosavljevic M, Trauner M, Schreiber F. Austrian consensus on the definition and treatment of portal hypertension and its complications. Endoscopy 2005 37 : 667 73.
-
(2005)
Endoscopy
, vol.37
, pp. 667-73
-
-
Peck-Radosavljevic, M.1
Trauner, M.2
Schreiber, F.3
-
40
-
-
34948824782
-
Nodular regenerative hyperplasia in patients with inflammatory bowel disease treated with azathioprine
-
Epub ahead of print.
-
Vernier-Massouille G, Cosnes J, Lemann M, et al. Nodular regenerative hyperplasia in patients with inflammatory bowel disease treated with azathioprine. Gut 2007 May 15 Epub ahead of print.
-
(2007)
Gut
-
-
Vernier-Massouille, G.1
Cosnes, J.2
Lemann, M.3
-
41
-
-
0034030858
-
Portal hypertension in the presence of minimal liver damage in Crohn's disease on long-term azathioprine: Possible endothelial cell injury
-
Arnott ID, Ghosh S. Portal hypertension in the presence of minimal liver damage in Crohn's disease on long-term azathioprine: Possible endothelial cell injury. Eur J Gastroenterol Hepatol 2000 12 : 569 73.
-
(2000)
Eur J Gastroenterol Hepatol
, vol.12
, pp. 569-73
-
-
Arnott, I.D.1
Ghosh, S.2
-
42
-
-
35448960942
-
Hepatotoxicity of long-term and low-dose 6-thioguanine in IBD
-
de Boer N, Gilissen L, Derijks L, et al. Hepatotoxicity of long-term and low-dose 6-thioguanine in IBD. Gastroenterology 2006 Suppl 1 S1327.
-
(2006)
Gastroenterology
, Issue.1
-
-
De Boer, N.1
Gilissen, L.2
Derijks, L.3
-
43
-
-
33846266585
-
Toxicity of 6-thioguanine: No hepatotoxicity in a series of IBD patients treated with long-term, low dose 6-thioguanine. Some evidence for dose or metabolite level dependent effects?
-
Gilissen LP, Derijks LJ, Driessen A, et al. Toxicity of 6-thioguanine: No hepatotoxicity in a series of IBD patients treated with long-term, low dose 6-thioguanine. Some evidence for dose or metabolite level dependent effects? Dig Liver Dis 2007 39 : 156 9.
-
(2007)
Dig Liver Dis
, vol.39
, pp. 156-9
-
-
Gilissen, L.P.1
Derijks, L.J.2
Driessen, A.3
-
44
-
-
21044449577
-
Nodular regenerative hyperplasia, portal vein thrombosis, and avascular hip necrosis due to hyperhomocysteinaemia
-
Buchel O, Roskams T, Van Damme B, et al. Nodular regenerative hyperplasia, portal vein thrombosis, and avascular hip necrosis due to hyperhomocysteinaemia. Gut 2005 54 : 1021 3.
-
(2005)
Gut
, vol.54
, pp. 1021-3
-
-
Buchel, O.1
Roskams, T.2
Van Damme, B.3
-
45
-
-
28144455912
-
Beta-blockers to prevent gastroesophageal varices in patients with cirrhosis
-
Portal Hypertension Collaborative Group.
-
Groszmann RJ, Garcia-Tsao G, Bosch J, et al. Portal Hypertension Collaborative Group. Beta-blockers to prevent gastroesophageal varices in patients with cirrhosis. N Engl J Med 2005 353 : 2254 61.
-
(2005)
N Engl J Med
, vol.353
, pp. 2254-61
-
-
Groszmann, R.J.1
Garcia-Tsao, G.2
Bosch, J.3
-
46
-
-
22144482338
-
Pharmacogenetic association with adverse drug reactions to azathioprine immunosuppressive therapy following liver transplantation
-
Breen DP, Marinaki AM, Arenas M, et al. Pharmacogenetic association with adverse drug reactions to azathioprine immunosuppressive therapy following liver transplantation. Liver Transpl 2005 11 : 826 33.
-
(2005)
Liver Transpl
, vol.11
, pp. 826-33
-
-
Breen, D.P.1
Marinaki, A.M.2
Arenas, M.3
-
47
-
-
27244452424
-
Nodular regenerative hyperplasia and thiopurines: The case for level-dependent toxicity
-
de Boer NK, Mulder CJ, van Bodegraven AA. Nodular regenerative hyperplasia and thiopurines: The case for level-dependent toxicity. Liver Transpl 2005 11 : 1300 1.
-
(2005)
Liver Transpl
, vol.11
, pp. 1300-1
-
-
De Boer, N.K.1
Mulder, C.J.2
Van Bodegraven, A.A.3
-
48
-
-
0023896137
-
Role of endothelial cell injury in the spectrum of azathioprine-induced liver disease after renal transplant: Light microscopy and ultrastructural observations
-
Haboubi NY, Ali HH, Whitwell HL, et al. Role of endothelial cell injury in the spectrum of azathioprine-induced liver disease after renal transplant: Light microscopy and ultrastructural observations. Am J Gastroenterol 1988 83 : 256 61.
-
(1988)
Am J Gastroenterol
, vol.83
, pp. 256-61
-
-
Haboubi, N.Y.1
Ali, H.H.2
Whitwell, H.L.3
-
49
-
-
0037443978
-
Prevention of variceal rebleeding
-
Bosch J, Garcia-Pagan JC. Prevention of variceal rebleeding. Lancet 2003 361 : 952 4.
-
(2003)
Lancet
, vol.361
, pp. 952-4
-
-
Bosch, J.1
Garcia-Pagan, J.C.2
|