Identification of cyclic peptides able to mimic the functional epitope of IgG1-Fc for human FcγRI

FASEB Journal

Volumn 23, Issue 2, 2009, Pages 575-585

  Bonetto, Stephane ^a   Spadola, Loredana ^b   Buchanan, Andrew G ^a   Jermutus, Lutz ^a,c   Lund, John ^a,c  

^a MEDIMMUNE   (United States)

^b ASTRAZENECA R AND D   (Sweden)

^c MEDIMMUNE LTD   (United Kingdom)

Author keywords

Consensus sequence; Discontinuous interface; Effector functions; Molecular modeling; Phage display; Single chain homodimer

Indexed keywords

CYCLOPEPTIDE; EPITOPE; FC GAMMA RECEPTOR 1; FC RECEPTOR; HOMODIMER; IMMUNOGLOBULIN FC FRAGMENT; IMMUNOGLOBULIN G1; SUPEROXIDE; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; DIMERIZATION; HYDROPHOBICITY; MOLECULAR MODEL; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN ISOLATION;

AMINO ACID SEQUENCE; BIOMIMETIC MATERIALS; CELLS, CULTURED; DATABASES, PROTEIN; EPITOPES; HUMANS; IMMUNOGLOBULIN FC FRAGMENTS; IMMUNOGLOBULIN G; MOLECULAR SEQUENCE DATA; PEPTIDES, CYCLIC; PHAGOCYTOSIS; PROTEIN BINDING; PROTEIN MULTIMERIZATION; RECEPTORS, IGG; SUPEROXIDES;

EID: 59649127411     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.08-117069     Document Type: Article

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