The mechanism of amyloid-fibril formation by stefin B: Temperature and protein concentration dependence of the rates

Proteins: Structure, Function and Bioinformatics

Volumn 74, Issue 2, 2009, Pages 425-436

  Škerget, Katja ^a   Vilfan, Andrej ^a   Pompe Novak, Maruša ^b   Turk, Vito ^a   Waltho, Jonathan P ^c,d   Turk, Dušan ^a   Žerovnik, Eva ^a  

^a JO EF STEFAN INSTITUTE   (Slovenia)

^b NATIONAL INSTITUTE OF BIOLOGY   (Slovenia)

^c UNIVERSITY OF SHEFFIELD   (United Kingdom)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Cystatin; Domain swapping; Enthalpy of activation; Kinetics of fibrillation; Model of amyloid fibril formation; Off pathway oligomers; Proline isomerization

Indexed keywords

AMYLOID; CYSTATIN; CYSTEINE PROTEINASE INHIBITOR; MUTANT PROTEIN; PROLINE; RECOMBINANT PROTEIN; STEFIN B; THIOFLAVINE; CYSTATIN B; THIAZOLE DERIVATIVE;

AMYLOIDOGENESIS; ARTICLE; CIRCULAR DICHROISM; CONCENTRATION RESPONSE; CONFORMATIONAL TRANSITION; ENTHALPY; ESCHERICHIA COLI; FLUORESCENCE; HUMAN; ISOMERIZATION; KINETICS; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN FOLDING; TEMPERATURE DEPENDENCE; TRANSMISSION ELECTRON MICROSCOPY; CHEMISTRY; METABOLISM; SPECTROFLUOROMETRY; TEMPERATURE; ULTRASTRUCTURE;

AMYLOID; CIRCULAR DICHROISM; CYSTATIN B; HUMANS; KINETICS; SPECTROMETRY, FLUORESCENCE; TEMPERATURE; THIAZOLES;

EID: 59449098817     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.22156     Document Type: Article

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