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Volumn 202, Issue 1-3, 2009, Pages 343-354

Evaluation of the pro-cognitive effects of the AMPA receptor positive modulator, 5-(1-piperidinylcarbonyl)-2,1,3-benzoxadiazole (CX691), in the rat

Author keywords

Acetylcholine; AMPA receptor positive modulator; BDNF; CX691; Dopamine; Learning and memory; Neurochemistry

Indexed keywords

ACETYLCHOLINE; AMPA RECEPTOR; BRAIN DERIVED NEUROTROPHIC FACTOR; DOPAMINE; FARAMPATOR; MESSENGER RNA; SCOPOLAMINE;

EID: 59449092174     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-008-1325-2     Document Type: Article
Times cited : (40)

References (66)
  • 1
    • 0030927941 scopus 로고    scopus 로고
    • Extensive cytotoxic lesions involving both the rhinal corticies and are TE impair recognition but spare alternation in the rat
    • JP Aggleton S Keen EC Warburton TJ Bussey 1997 Extensive cytotoxic lesions involving both the rhinal corticies and are TE impair recognition but spare alternation in the rat Brain Res Bull 43 279 287
    • (1997) Brain Res Bull , vol.43 , pp. 279-287
    • Aggleton, J.P.1    Keen, S.2    Warburton, E.C.3    Bussey, T.J.4
  • 2
    • 0032551573 scopus 로고    scopus 로고
    • AMPA receptor desensitization modulates synaptic responses induced by repetitive afferent stimulation in hippocampal slices
    • A Arai G Lynch 1998 AMPA receptor desensitization modulates synaptic responses induced by repetitive afferent stimulation in hippocampal slices Brain Res 799 235 242
    • (1998) Brain Res , vol.799 , pp. 235-242
    • Arai, A.1    Lynch, G.2
  • 3
    • 0034975982 scopus 로고    scopus 로고
    • Positive modulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors in prefrontal cortical pyramidal neurons by a novel allosteric potentiator
    • PJ Baumbarger M Muhlhauser J Zhai CR Yang ES Nisenbaum 2001 Positive modulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors in prefrontal cortical pyramidal neurons by a novel allosteric potentiator J Pharmacol Exp Ther 298 86 102
    • (2001) J Pharmacol Exp Ther , vol.298 , pp. 86-102
    • Baumbarger, P.J.1    Muhlhauser, M.2    Zhai, J.3    Yang, C.R.4    Nisenbaum, E.S.5
  • 4
    • 33749169804 scopus 로고
    • A simple objective treatment for measuring flexibility in thinking
    • EA Berg 1948 A simple objective treatment for measuring flexibility in thinking J Gen Psych 39 15 22
    • (1948) J Gen Psych , vol.39 , pp. 15-22
    • Berg, E.A.1
  • 5
    • 0034212645 scopus 로고    scopus 로고
    • Medial frontal cortex mediates perceptual attentional set shifting in the rat
    • JM Birrell VJ Brown 2000 Medial frontal cortex mediates perceptual attentional set shifting in the rat J Neurosci 20 4320 4324
    • (2000) J Neurosci , vol.20 , pp. 4320-4324
    • Birrell, J.M.1    Brown, V.J.2
  • 6
    • 17844407467 scopus 로고    scopus 로고
    • Therapeutic potential of positive AMPA modulators and their relationship to AMPA receptor subunits. A review of preclinical data
    • M Black 2005 Therapeutic potential of positive AMPA modulators and their relationship to AMPA receptor subunits. A review of preclinical data Psychopharmacology 179 154 163
    • (2005) Psychopharmacology , vol.179 , pp. 154-163
    • Black, M.1
  • 7
    • 0027476024 scopus 로고
    • A synaptic model of memory: Long-term potentiation in the hippocampus
    • TV Bliss GL Collingridge 1993 A synaptic model of memory: long-term potentiation in the hippocampus Nature 361 31 39
    • (1993) Nature , vol.361 , pp. 31-39
    • Bliss, T.V.1    Collingridge, G.L.2
  • 8
    • 0344688205 scopus 로고    scopus 로고
    • The effects of IDRA 21, a positive modulator of the AMPA receptor, on delayed matching performance by young and aged rhesus monkeys
    • JJ Buccafusco T Weiser K Winter K Klinder AV Terry 2004 The effects of IDRA 21, a positive modulator of the AMPA receptor, on delayed matching performance by young and aged rhesus monkeys Neuropharmacology 46 10 22
    • (2004) Neuropharmacology , vol.46 , pp. 10-22
    • Buccafusco, J.J.1    Weiser, T.2    Winter, K.3    Klinder, K.4    Terry, A.V.5
  • 10
    • 0034554854 scopus 로고    scopus 로고
    • Impaired recognition memory in rats after damage to the hippocampus
    • RE Clark SM Zola LR Squire 2000 Impaired recognition memory in rats after damage to the hippocampus J Neurosci 20 8853 8860
    • (2000) J Neurosci , vol.20 , pp. 8853-8860
    • Clark, R.E.1    Zola, S.M.2    Squire, L.R.3
  • 11
    • 0026529429 scopus 로고
    • Nootropic drugs positively modulate alpha-amino-3-hydroxy-5-methyl-4- isoxazolepropionic acid-sensitive glutamate receptors in neuronal cultures
    • A Copani AA Genazzani G Aleppo G Casabona PL Canonico U Scapagnini F Nicoletti 1992 Nootropic drugs positively modulate alpha-amino-3-hydroxy-5- methyl-4-isoxazolepropionic acid-sensitive glutamate receptors in neuronal cultures J Neurochem 58 1199 1204
    • (1992) J Neurochem , vol.58 , pp. 1199-1204
    • Copani, A.1    Genazzani, A.A.2    Aleppo, G.3    Casabona, G.4    Canonico, P.L.5    Scapagnini, U.6    Nicoletti, F.7
  • 12
    • 0028821928 scopus 로고
    • Modulation of learning processes by ionotropic glutamate receptor ligands
    • W Danysz W Zajaczkowski CG Parsons 1995 Modulation of learning processes by ionotropic glutamate receptor ligands Behav Pharmacol 6 455 474
    • (1995) Behav Pharmacol , vol.6 , pp. 455-474
    • Danysz, W.1    Zajaczkowski, W.2    Parsons, C.G.3
  • 13
    • 0028921084 scopus 로고
    • 1-BCP, a memory-enhancing agent, selectively potentiates AMPA-induced [3H]norepinephrine release in rat hippocampal slices
    • MA Desai MJ Valli JA Monn DD Schoepp 1995 1-BCP, a memory-enhancing agent, selectively potentiates AMPA-induced [3H]norepinephrine release in rat hippocampal slices Neuropharmacology 34 141 147
    • (1995) Neuropharmacology , vol.34 , pp. 141-147
    • Desai, M.A.1    Valli, M.J.2    Monn, J.A.3    Schoepp, D.D.4
  • 15
    • 0032189944 scopus 로고    scopus 로고
    • Effects of lesions of the substantia innominata ventra pallidum, globus pallidus and medial septum on rat's performance in object-recognition and radial-maze tasks: Physostigmine and amphetamine treatments
    • A Ennaceur 1998 Effects of lesions of the substantia innominata ventra pallidum, globus pallidus and medial septum on rat's performance in object-recognition and radial-maze tasks: physostigmine and amphetamine treatments Pharmacol Res 38 251 263
    • (1998) Pharmacol Res , vol.38 , pp. 251-263
    • Ennaceur, A.1
  • 16
    • 0023691166 scopus 로고
    • A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral data
    • A Ennaceur J Delacour 1988 A new one-trial test for neurobiological studies of memory in rats. 1: behavioral data Behav Brain Res 31 47 59
    • (1988) Behav Brain Res , vol.31 , pp. 47-59
    • Ennaceur, A.1    Delacour, J.2
  • 17
    • 0024400560 scopus 로고
    • A new one-trial test for neurobiological studies of memory in rats. II: Effects of piracetam and pramiracetam
    • A Ennaceur A Cavoy JC Costa J Delacour 1989 A new one-trial test for neurobiological studies of memory in rats. II: Effects of piracetam and pramiracetam Behav Brain Res 33 197 207
    • (1989) Behav Brain Res , vol.33 , pp. 197-207
    • Ennaceur, A.1    Cavoy, A.2    Costa, J.C.3    Delacour, J.4
  • 18
    • 0030272766 scopus 로고    scopus 로고
    • Neurotoxic lesions of the perirhinal cortex do not mimic the behavioural effects of fornix transection in the rat
    • A Ennaceur N Neave JP Aggleton 1996 Neurotoxic lesions of the perirhinal cortex do not mimic the behavioural effects of fornix transection in the rat Behav Brain Res 80 9 25
    • (1996) Behav Brain Res , vol.80 , pp. 9-25
    • Ennaceur, A.1    Neave, N.2    Aggleton, J.P.3
  • 19
    • 0030977716 scopus 로고    scopus 로고
    • Spontaneous object recognition and object location memory in rats: The effects of lesions in the cingulate cortices, the medial prefrontal cortex, the cingulum bundle and the fornix
    • A Ennaceur N Neave JP Aggleton 1997 Spontaneous object recognition and object location memory in rats: the effects of lesions in the cingulate cortices, the medial prefrontal cortex, the cingulum bundle and the fornix Exp Brain Res 113 509 519
    • (1997) Exp Brain Res , vol.113 , pp. 509-519
    • Ennaceur, A.1    Neave, N.2    Aggleton, J.P.3
  • 20
    • 0025132860 scopus 로고
    • Identification of cells in rat brain and peripheral tissues expressing mRNA for members of the nerve growth factor family
    • P Ernfors C Wetmore L Olson H Persson 1990 Identification of cells in rat brain and peripheral tissues expressing mRNA for members of the nerve growth factor family Neuron 5 511 526
    • (1990) Neuron , vol.5 , pp. 511-526
    • Ernfors, P.1    Wetmore, C.2    Olson, L.3    Persson, H.4
  • 23
    • 0027143781 scopus 로고
    • A drug that facilitates glutamatergic transmission reduces exploratory activity and improves performance in a learning-dependent task
    • R Granger U Staubli M Davis Y Perez L Nilsson GA Rogers G Lynch 1993 A drug that facilitates glutamatergic transmission reduces exploratory activity and improves performance in a learning-dependent task Synapse 15 326 329
    • (1993) Synapse , vol.15 , pp. 326-329
    • Granger, R.1    Staubli, U.2    Davis, M.3    Perez, Y.4    Nilsson, L.5    Rogers, G.A.6    Lynch, G.7
  • 24
    • 0032053963 scopus 로고    scopus 로고
    • Facilitative effects of the ampakine CX516 on short-term memory in rats: Correlations with hippocampal neuronal activity
    • RE Hampson G Rogers G Lynch SA Deadwyler 1998 Facilitative effects of the ampakine CX516 on short-term memory in rats: correlations with hippocampal neuronal activity J Neurosci 18 2748 2763
    • (1998) J Neurosci , vol.18 , pp. 2748-2763
    • Hampson, R.E.1    Rogers, G.2    Lynch, G.3    Deadwyler, S.A.4
  • 26
    • 1542344509 scopus 로고    scopus 로고
    • Differential autoreceptor control of extracellular 5-HT in guinea pig and rat: Species and regional differences
    • ZA Hughes LA Dawson 2004 Differential autoreceptor control of extracellular 5-HT in guinea pig and rat: species and regional differences Psychopharmacology 172 87 93
    • (2004) Psychopharmacology , vol.172 , pp. 87-93
    • Hughes, Z.A.1    Dawson, L.A.2
  • 29
    • 0025356607 scopus 로고
    • Allosteric potentiation of quisqualate receptors by a nootropic drug aniracetam
    • I Ito S Tanabe A Kohda H Sugiyama 1990 Allosteric potentiation of quisqualate receptors by a nootropic drug aniracetam J Physiol 424 533 543
    • (1990) J Physiol , vol.424 , pp. 533-543
    • Ito, I.1    Tanabe, S.2    Kohda, A.3    Sugiyama, H.4
  • 30
    • 0027527896 scopus 로고
    • Long term potentiation and mechanisms of memory
    • I Izquierdo 1993 Long term potentiation and mechanisms of memory Drug Dev Res 30 1 17
    • (1993) Drug Dev Res , vol.30 , pp. 1-17
    • Izquierdo, I.1
  • 31
    • 17744387125 scopus 로고    scopus 로고
    • Ionotropic and metabotropic glutamate receptor structure and pharmacology
    • JN Kew JA Kemp 2005 Ionotropic and metabotropic glutamate receptor structure and pharmacology Psychopharmacology 179 4 29
    • (2005) Psychopharmacology , vol.179 , pp. 4-29
    • Kew, J.N.1    Kemp, J.A.2
  • 32
    • 0346250850 scopus 로고    scopus 로고
    • 6 receptor antagonist SB-271046 enhances monoamine release in the rat medial prefrontal cortex
    • 6 receptor antagonist SB-271046 enhances monoamine release in the rat medial prefrontal cortex Synapse 51 158 164
    • (2004) Synapse , vol.51 , pp. 158-164
    • Lacroix, L.P.1    Dawson, L.A.2    Hagan, J.J.3    Heidbreder, C.A.4
  • 33
    • 0033994676 scopus 로고    scopus 로고
    • Positive modulation of AMPA receptors increases neurotrophin expression by hippocampal and cortical neurons
    • JC Lauterborn G Lynch P Vanderklish A Arai CM Gall 2000 Positive modulation of AMPA receptors increases neurotrophin expression by hippocampal and cortical neurons J Neurosci 20 8 21
    • (2000) J Neurosci , vol.20 , pp. 8-21
    • Lauterborn, J.C.1    Lynch, G.2    Vanderklish, P.3    Arai, A.4    Gall, C.M.5
  • 35
    • 18244422005 scopus 로고    scopus 로고
    • Effects of S 18986-1, a novel cognitive enhancer, on memory performances in an object recognition task in rats
    • C Lebrun E Pillière P Lestage 2000 Effects of S 18986-1, a novel cognitive enhancer, on memory performances in an object recognition task in rats Eur J Pharmacol 401 205 212
    • (2000) Eur J Pharmacol , vol.401 , pp. 205-212
    • Lebrun, C.1    Pillière, E.2    Lestage, P.3
  • 36
    • 0032535354 scopus 로고    scopus 로고
    • Fear and the brain: Where have we been, and where are we going?
    • J LeDoux 1998 Fear and the brain: where have we been, and where are we going? Biol Psychiatry 44 1229 1238
    • (1998) Biol Psychiatry , vol.44 , pp. 1229-1238
    • Ledoux, J.1
  • 37
    • 0034993814 scopus 로고    scopus 로고
    • Regulation of BDNF expression in primary neuron culture by LY392098, a novel AMPA receptor potentiator
    • B Legutko X Li P Skolnick 2001 Regulation of BDNF expression in primary neuron culture by LY392098, a novel AMPA receptor potentiator Neuropharmacology 40 1019 1027
    • (2001) Neuropharmacology , vol.40 , pp. 1019-1027
    • Legutko, B.1    Li, X.2    Skolnick, P.3
  • 40
    • 0037359267 scopus 로고    scopus 로고
    • BDNF and activity-dependent synaptic modulation
    • B Lu 2008 BDNF and activity-dependent synaptic modulation Learning and memory 10 86 98
    • (2008) Learning and Memory , vol.10 , pp. 86-98
    • Lu, B.1
  • 41
    • 33748762214 scopus 로고    scopus 로고
    • Ampakines and the threefold path to cognitive enhancement
    • G Lynch CM Gall 2006 Ampakines and the threefold path to cognitive enhancement Trends Neurosci 29 554 562
    • (2006) Trends Neurosci , vol.29 , pp. 554-562
    • Lynch, G.1    Gall, C.M.2
  • 43
    • 0346461652 scopus 로고    scopus 로고
    • Synaptic plasticity and AMPA receptor trafficking
    • RC Malenka 2003 Synaptic plasticity and AMPA receptor trafficking Ann NY Acad Sci 1003 1 11
    • (2003) Ann NY Acad Sci , vol.1003 , pp. 1-11
    • Malenka, R.C.1
  • 44
    • 24644432884 scopus 로고    scopus 로고
    • Synaptic mechanisms of associative memory in the amygdala
    • S Maren 2005 Synaptic mechanisms of associative memory in the amygdala Neuron 47 783 786
    • (2005) Neuron , vol.47 , pp. 783-786
    • Maren, S.1
  • 45
    • 0344393796 scopus 로고    scopus 로고
    • Orbital prefrontal cortex mediates reversal learning and not attentional set shifting in the rat
    • K McAlonan VJ Brown 2003 Orbital prefrontal cortex mediates reversal learning and not attentional set shifting in the rat Behav Brain Res 146 97 103
    • (2003) Behav Brain Res , vol.146 , pp. 97-103
    • McAlonan, K.1    Brown, V.J.2
  • 46
    • 0025332303 scopus 로고
    • Pharmacology of nootropics and metabolically active compounds in relation to their use in dementia
    • CD Nicholson 1990 Pharmacology of nootropics and metabolically active compounds in relation to their use in dementia Psychopharmacology 101 147 159
    • (1990) Psychopharmacology , vol.101 , pp. 147-159
    • Nicholson, C.D.1
  • 48
    • 59449084578 scopus 로고
    • Academic Press San Diego
    • Paxinos G, Watson C (1986) The rat brain in stereotaxic coordinates. Academic Press, San Diego
    • (1986)
    • Paxinos, G.1    Watson, C.2
  • 50
    • 0032952996 scopus 로고    scopus 로고
    • Aniracetam, 1-BCP and cyclothiazide differentially modulate the function of NMDA and AMPA receptors mediating enhancement of noradrenaline release in rat hippocampal slices
    • A Pittaluga A Bonfanti D Arvigo M Raiteri 1999 Aniracetam, 1-BCP and cyclothiazide differentially modulate the function of NMDA and AMPA receptors mediating enhancement of noradrenaline release in rat hippocampal slices Naunyn Schmiedebergs Arch Pharmacol 359 272 279
    • (1999) Naunyn Schmiedebergs Arch Pharmacol , vol.359 , pp. 272-279
    • Pittaluga, A.1    Bonfanti, A.2    Arvigo, D.3    Raiteri, M.4
  • 51
    • 0021950749 scopus 로고
    • Effects of aniracetam on delayed matching-to-sample performance of monkeys and pigeons
    • MJ Pontecorvo HL Evans 1985 Effects of aniracetam on delayed matching-to-sample performance of monkeys and pigeons Pharmacol Biochem Behav 22 745 752
    • (1985) Pharmacol Biochem Behav , vol.22 , pp. 745-752
    • Pontecorvo, M.J.1    Evans, H.L.2
  • 52
    • 24944535699 scopus 로고    scopus 로고
    • Facilitation of task performance and removal of the effects of sleep deprivation by an ampakine (CX717) in nonhuman primates
    • LJ Porrino JB Daunais GA Rogers RE Hampson SA Deadwyler 2005 Facilitation of task performance and removal of the effects of sleep deprivation by an ampakine (CX717) in nonhuman primates PLoS Biology 3 e299
    • (2005) PLoS Biology , vol.3 , pp. 299
    • Porrino, L.J.1    Daunais, J.B.2    Rogers, G.A.3    Hampson, R.E.4    Deadwyler, S.A.5
  • 53
    • 0036751341 scopus 로고    scopus 로고
    • LY404187: A novel positive allosteric modulator of AMPA receptors
    • JC Quirk ES Nisenbaum 2002 LY404187: a novel positive allosteric modulator of AMPA receptors CNS Drug Rev 8 255 282
    • (2002) CNS Drug Rev , vol.8 , pp. 255-282
    • Quirk, J.C.1    Nisenbaum, E.S.2
  • 54
    • 0029093419 scopus 로고
    • LTP is accompanied by commensurate enhancement of auditory-evoked responses in a fear conditioning circuit
    • MT Rogan JE LeDoux 1995 LTP is accompanied by commensurate enhancement of auditory-evoked responses in a fear conditioning circuit Neuron 15 127 136
    • (1995) Neuron , vol.15 , pp. 127-136
    • Rogan, M.T.1    Ledoux, J.E.2
  • 55
    • 0342601397 scopus 로고    scopus 로고
    • AMPA receptor facilitation accelerates fear learning without altering the level of conditioned fear acquired
    • MT Rogan UV Stäubli JE LeDoux 1997 AMPA receptor facilitation accelerates fear learning without altering the level of conditioned fear acquired J Neurosci 17 5928 5935
    • (1997) J Neurosci , vol.17 , pp. 5928-5935
    • Rogan, M.T.1    Stäubli, U.V.2    Ledoux, J.E.3
  • 56
    • 2342448516 scopus 로고    scopus 로고
    • S 18986, a positive modulator of AMPA receptors with cognition-enhancing properties, increases ACh release in the hippocampus of young and aged rat
    • S Rosi MG Giovannini PJ Lestage C Muñoz LD Corte G Pepeu 2004 S 18986, a positive modulator of AMPA receptors with cognition-enhancing properties, increases ACh release in the hippocampus of young and aged rat Neurosci Lett 361 120 123
    • (2004) Neurosci Lett , vol.361 , pp. 120-123
    • Rosi, S.1    Giovannini, M.G.2    Lestage, P.J.3    Muñoz, C.4    Corte, L.D.5    Pepeu, G.6
  • 57
    • 0024523079 scopus 로고
    • Effects of N-(2,6-dimethylphenyl)-2-(2-oxo-1-pyrrolidinyl)aceamide (DM-9384) on learning and memory in rats
    • T Sakurai H Ojima T Yamasaki H Kojima A Akashi 1989 Effects of N-(2,6-dimethylphenyl)-2-(2-oxo-1-pyrrolidinyl)aceamide (DM-9384) on learning and memory in rats Jpn J Pharmacol 50 47 53
    • (1989) Jpn J Pharmacol , vol.50 , pp. 47-53
    • Sakurai, T.1    Ojima, H.2    Yamasaki, T.3    Kojima, H.4    Akashi, A.5
  • 58
    • 0034536215 scopus 로고    scopus 로고
    • The neurotrophin hypothesis for synaptic plasticity
    • AF Schinder M Poo 2000 The neurotrophin hypothesis for synaptic plasticity Trends Neurosci 23 639 645
    • (2000) Trends Neurosci , vol.23 , pp. 639-645
    • Schinder, A.F.1    Poo, M.2
  • 59
    • 30044444757 scopus 로고    scopus 로고
    • Synaptic expression of glutamate receptor after encoding of fear memory in the rat amygdale
    • Y Shiu-Hwa M Sheng-chun L Hui-Ching G Po-Wu 2006 Synaptic expression of glutamate receptor after encoding of fear memory in the rat amygdale Mol Pharmacol 69 299 308
    • (2006) Mol Pharmacol , vol.69 , pp. 299-308
    • Shiu-Hwa, Y.1    Sheng-Chun, M.2    Hui-Ching, L.3    Po-Wu, G.4
  • 60
    • 0023181845 scopus 로고
    • Interactions between oxiracetam, aniracetam and scopolamine on behaviour and brain acetylcholine
    • G Spignoli G Pepeu 1987 Interactions between oxiracetam, aniracetam and scopolamine on behaviour and brain acetylcholine Pharmacol Biochem Behav 27 491 495
    • (1987) Pharmacol Biochem Behav , vol.27 , pp. 491-495
    • Spignoli, G.1    Pepeu, G.2
  • 61
    • 0028088995 scopus 로고
    • Facilitation of glutamate receptors enhances memory
    • U Staubli G Rogers G Lynch 1994 Facilitation of glutamate receptors enhances memory Proc Natl Acad Sci USA 91 777 781
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 777-781
    • Staubli, U.1    Rogers, G.2    Lynch, G.3
  • 63
    • 0023925055 scopus 로고
    • Effects of nootropic drugs in a scopolamine-induced amnesia model in mice
    • R Verloes AM Scotto J Gobert E Wülfert 1988 Effects of nootropic drugs in a scopolamine-induced amnesia model in mice Psychopharmacology 95 226 230
    • (1988) Psychopharmacology , vol.95 , pp. 226-230
    • Verloes, R.1    Scotto, A.M.2    Gobert, J.3    Wülfert, E.4
  • 64
    • 0029131217 scopus 로고
    • Lesions of rat perirhinal cortex exacerbate the memory deficit observed following damage to the fimbria-fornix
    • KA Wiig DK Bilkey 1995 Lesions of rat perirhinal cortex exacerbate the memory deficit observed following damage to the fimbria-fornix Behav Neurosci 109 620 630
    • (1995) Behav Neurosci , vol.109 , pp. 620-630
    • Wiig, K.A.1    Bilkey, D.K.2
  • 65
    • 0027157935 scopus 로고
    • Impaired object recognition memory in rats following ischaemia-induced damage to the hippocampus
    • ER Wood DG Mumby JPJ Pinel AG Phillips 1993 Impaired object recognition memory in rats following ischaemia-induced damage to the hippocampus Behav Neurosci 107 51 62
    • (1993) Behav Neurosci , vol.107 , pp. 51-62
    • Wood, E.R.1    Mumby, D.G.2    Pinel, J.P.J.3    Phillips, A.G.4
  • 66
    • 0027064919 scopus 로고
    • Diazoxide blocks glutamate desensitization and prolongs excitatory postsynaptic currents in rat hippocampal neurons
    • KA Yamada SM Rothman 1992 Diazoxide blocks glutamate desensitization and prolongs excitatory postsynaptic currents in rat hippocampal neurons J Physiol 458 409 423
    • (1992) J Physiol , vol.458 , pp. 409-423
    • Yamada, K.A.1    Rothman, S.M.2


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