Orbital prefrontal cortex mediates reversal learning and not attentional set shifting in the rat

Behavioural Brain Research

Volumn 146, Issue 1-2, 2003, Pages 97-103

  McAlonan, Kerry ^a   Brown, Verity J ^a  

^a UNIVERSITY OF ST ANDREWS   (United Kingdom)

Author keywords

Amygdala; Goal directed; Habit; Orbitofrontal; Rule learning

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISSOCIATION; LEARNING; MALE; MONKEY; MOTOR DYSFUNCTION; NONHUMAN; ORBIT; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT; RAT STRAIN; TASK PERFORMANCE; TRAINING;

EID: 0344393796     PISSN: 01664328     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbr.2003.09.019     Document Type: Article

References (32)

1. Baxter M.G., Parker A., Lindner C.C., Izquierdo A.D., Murray E.A. Control of response selection by reinforcer value requires interaction of amygdala and orbital prefrontal cortex. J. Neurosci. 20:2000;4311-4319.
2. Bechara A., Damasio H., Damasio A.R. Emotion, decision making and the orbitofrontal cortex. Cereb. Cortex. 10:2000;295-307.
3. Bechara A., Damasio H., Tranel D., Damasio A.R. Deciding advantageously before knowing the advantageous strategy. Science. 275:1997;1293-1295.
4. Birrell J.M., Brown V.J. Medial frontal cortex mediates perceptual attentional set shifting in the rat. J. Neurosci. 20:2000;4320-4324.
5. Brown V.J., Bowman E.M. Rodent models of prefrontal cortical function. Trends Neurosci. 25:2002;340-343.
6. Cardinal R.N., Parkinson J.A., Hall J., Everitt B.J. Emotion and motivation: the role of the amygdala, ventral striatum, and prefrontal cortex. Neurosci. Biobehav. Rev. 26:2002;321-352.
7. Damasio AR. Descartes error. New York: G.P. Putman; 1994.
8. Dias R., Robbins T.W., Roberts A.C. Dissociation in prefrontal cortex of affective and attentional shifts. Nature. 380:1996;69-72.
9. Dias R., Robbins T.W., Roberts A.C. Primate analogue of the Wisconsin Card Sorting Test: effects of excitotoxic lesions of the prefrontal cortex in the marmoset. Behav. Neurosci. 110:1996;872-886.
10. Dias R., Robbins T.W., Roberts A.C. Dissociable forms of inhibitory control within prefrontal cortex with an analog of the Wisconsin Card Sort Test: restriction to novel situations and independence from "on-line" processing. J. Neurosci. 17:1997;9285-9297.
11. Downes J.J., Roberts A.C., Sahakian B.J., Evenden J.L., Morris R.G., Robbins T.W. Impaired extra-dimensional shift performance in medicated and unmedicated Parkinson's disease: evidence for a specific attentional dysfunction. Neuropsychologia. 27:1989;1329-1343.
12. Ferry A.T., Lu X.C., Price J.L. Effects of excitotoxic lesions in the ventral striatopallidal-thalamocortical pathway on odor reversal learning: inability to extinguish an incorrect response. Exp. Brain Res. 131:2000;320-335.
13. Gallagher M., McMahan R.W., Schoenbaum G. Orbitofrontal cortex and representation of incentive value in associative learning. J. Neurosci. 19:1999;6610-6614.
14. Iversen S.D., Mishkin M. Perseverative interference in monkeys following selective lesions of the inferior prefrontal convexity. Exp. Brain Res. 11:1970;376-386.
15. Lipton P.A., Alvarez P., Eichenbaum H. Crossmodal associative memory representations in rodent orbitofrontal cortex. Neuron. 22:1999;349-359.
16. Mcalonan K, Brown VJ. Lesions of rat orbital prefrontal cortex impair reversal learning but not attentional set-shifting, vol. 286.4. Washington, DC: Society for Neuroscience; 2002.
17. Nauta W.J. The problem of the frontal lobe: a reinterpretation. J. Psychiatr. Res. 8:1971;167-187.
18. Owen A.M., Roberts A.C., Polkey C.E., Sahakian B.J., Robbins T.W. Extra-dimensional versus intra-dimensional set shifting performance following frontal lobe excisions, temporal lobe excisions or amygdalo-hippocampectomy in man. Neuropsychologia. 29:1991;993-1006.
19. Paxinos GAWC. The rat brain in stereotaxic coordinates, 2nd ed. San Diego, CA: Academic Press; 1986.
20. Ramus S.J., Eichenbaum H. Neural correlates of olfactory recognition memory in the rat orbitofrontal cortex. J. Neurosci. 20:2000;8199-8208.
21. Roberts A.C., De Salvia M.A., Wilkinson L.S., Collins P., Muir J.L., Everitt B.J.et al. 6-Hydroxydopamine lesions of the prefrontal cortex in monkeys enhance performance on an analog of the Wisconsin Card Sort Test: possible interactions with subcortical dopamine. J. Neurosci. 14:1994;2531-2544.
22. Rolls ET. The orbitofrontal cortex. Philos Trans R Soc Lond B: Biol Sci 1996;351:1433-43; discussion 1443-4.
23. Rolls E.T., Critchley H.D., Browning A.S., Hernadi I., Lenard L. Responses to the sensory properties of fat of neurons in the primate orbitofrontal cortex. J. Neurosci. 19:1999;1532-1540.
24. Schoenbaum G., Chiba A.A., Gallagher M. Orbitofrontal cortex and basolateral amygdala encode expected outcomes during learning. Nat. Neurosci. 1:1998;155-159.
25. Schoenbaum G., Chiba A.A., Gallagher M. Neural encoding in orbitofrontal cortex and basolateral amygdala during olfactory discrimination learning. J. Neurosci. 19:1999;1876-1884.
26. Schoenbaum G., Eichenbaum H. Information coding in the rodent prefrontal cortex. I. Single-neuron activity in orbitofrontal cortex compared with that in pyriform cortex. J. Neurophysiol. 74:1995;733-750.
27. Schoenbaum G., Eichenbaum H. Information coding in the rodent prefrontal cortex. II. Ensemble activity in orbitofrontal cortex. J. Neurophysiol. 74:1995;751-762.
28. Schoenbaum G., Setlow B., Nugent S.L., Saddoris M.P., Gallagher M. Lesions of orbitofrontal cortex and basolateral amygdala complex disrupt acquisition of odor-guided discriminations and reversals. Learn. Mem. 10:2003;129-140.
29. Slamecka N.J. A methodological analysis of shift paradigms in human discrimination learning. Psychol. Bull. 69:1968;423-438.
30. Thorpe S.J., Rolls E.T., Maddison S. The orbitofrontal cortex: neuronal activity in the behaving monkey. Exp. Brain Res. 49:1983;93-115.
31. Tremblay L., Schultz W. Relative reward preference in primate orbitofrontal cortex. Nature. 398:1999;704-708.
32. Winer B. Statistical principles in experimental design, 2nd ed. New York: McGraw-Hill; 1971.