AMPA receptor desensitization modulates synaptic responses induced by repetitive afferent stimulation in hippocampal slices

Brain Research

Volumn 799, Issue 2, 1998, Pages 235-242

  Arai, Amy ^a   Lynch, Gary ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

CA1; Cyclothiazide; Excised patch; Long term potentiation, LTP; Pyramidal neuron; Synaptic plasticity; Theta burst

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID B RECEPTOR; AMPA RECEPTOR; CYCLOTHIAZIDE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL TISSUE; ARTICLE; HIPPOCAMPUS; LONG TERM POTENTIATION; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; RECEPTOR DOWN REGULATION; SENSORY NERVE; SENSORY STIMULATION; SYNAPTIC TRANSMISSION;

ANIMALS; BENZOTHIADIAZINES; ELECTRIC STIMULATION; EXCITATORY POSTSYNAPTIC POTENTIALS; GLUTAMIC ACID; HIPPOCAMPUS; KINETICS; NEURONS, AFFERENT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, AMPA; SYNAPSES;

EID: 0032551573     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)00447-8     Document Type: Article

References (23)

1. A. Arai, G. Lynch, Factors regulating the magnitude of long-term potentiation induced by theta pattern stimulation, Brain Res. 598 (1992) 173-184.
2. A. Arai, G. Lynch, Response to repetitive stimulation of AMPA receptors in patches excised from fields CA1 and CA3 of the hippocampus, Brain Res. 716 (1996) 202-206.
3. A. Arai, G. Lynch, The waveform of synaptic transmission at hippocampal synapses is not determined by AMPA receptor desensitization, Brain. Res. 799 (1998) 230-234.
4. A. Arai, J. Black, G. Lynch, Origins of the variations in long-term potentiation between synapses in the basal versus apical dendrites of hippocampal neurons, Hippocampus 4 (1994) 1-10.
5. A. Arai, J. Silberg, M. Kessler, G. Lynch, Effect of thiocyanate on AMPA receptor mediated responses in excised patches and hippocampal slices, Neuroscience 66 (1995) 815-827.
6. A. Arai, M. Kessler, G. Rogers, G. Lynch, Effects of a memory enhancing drug on AMPA receptor currents and synaptic transmission in hippocampus, J. Pharmacol. Exp. Ther. 278 (1996) 627-638.
7. A. Arai, M. Kessler, J. Ambros-Ingerson, A. Quan, E. Yigiter, G. Rogers, G. Lynch, Effects of a centrally active benzoylpiperidine drug on AMPA receptor kinetics, Neuroscience 75 (1996) 573-585.
8. J.D. Clements, R.A. Lester, G. Tong, C.E. Jahr, G.L. Westbrook, The time course of glutamate in the synaptic cleft, Science 258 (1992) 1498-1501.
9. D. Colquhoun, P. Jonas, B. Sakmann, Action of brief pulses of glutamate on AMPA/kainate receptors in patches from different neurones of rat hippocampal slices, J. Physiol. 458 (1992) 261-287.
10. R. Creager, T. Dunwiddie, G. Lynch, Paired-pulse and frequency facilitation in the CA1 region of the in vivo rat hippocampus, J. Physiol. 299 (1980) 409-424.
11. J.S. Diamond, C.E. Jahr, Asynchronous release of synaptic vesicles determines the time course of the AMPA receptor-mediated EPSC, Neuron 15 (1995) 1097-1107.
12. R.A. Hall, M. Kessler, G. Lynch, Evidence that high and low affinity AMPA binding sites reflect membrane-dependent states of a single receptor, J. Neurochem. 59 (1992) 1997-2004.
13. J. Larson, T. Le, R.A. Hall, G. Lynch, Effects of cyclothiazide on synaptic responses in slices of adult and neonatal rat hippocampus, NeuroReport 5 (1994) 389-392.
14. H. Monyer, P.H. Seeburg, W. Wisden, Glutamate-operated channels: developmentally early and mature form arise by alternative splicing, Neuron 6 (1991) 799-810.
15. J. Mosbacher, R. Schoepfer, H. Monyer, N. Burnashev, P. Seeburg, J.P. Ruppersberg, A molecular determinant for submillisecond desensitization in glutamate receptors, Science 266 (1994) 1059-1062.
16. D. Muller, G. Lynch, Rate-limiting step for transmission at excitatory synapses in hippocampus, Synapse 3 (1989) 67-73.
17. T. Otis, S. Zhang, L.O. Trussell, Direct measurement of AMPA receptor desensitization induced by glutamatergic synaptic transmission, J. Neurosci. 16 (1996) 7496-7504.
18. B. Sommer, K. Keinanen, T.A. Verdoorn, W. Wisden, N. Burnashev, A. Herb, M. Kohler, T. Takagi, B. Sakmann, P.H. Seeburg, Flip and flop: a cell-specific functional switch in glutamate-operated channels of the CNS, Science 249 (1990) 1580-1585.
19. C.-M. Tang, Q.-Y. Shi, A. Katchman, G. Lynch, Modulation of the time course of fast EPSCs and glutamate channel kinetics by aniracetam, Science 254 (1991) 288-290.
20. C.-M. Tang, M. Margulis, Q.-Y. Shi, A. Fielding, Saturation of postsynaptic glutamate receptors after quantal release of transmitter, Neuron 13 (1994) 1385-1393.
21. C.H. Vanderwolf, Hippocampal electrical activity and voluntary movement in the rat, Electroencephalogr. Clin. Neurophysiol. 26 (1969) 407-418.
22. R.P. Vertes, Brainstem modulation of the hippocampus: anatomy, physiology, and significance, in: R.L. Isaacson, K.H. Pribram (Eds.), The Hippocampus, Vol. 3, Plenum, New York, 1986.
23. L. Vyklicky Jr., D.K. Patneau, M.L. Mayer, Modulation of excitatory synaptic transmission by drugs that reduce desensitization at AMPA/kainate receptors, Neuron 7 (1991) 971-984.