Allergies and childhood leukemia

Blood Cells, Molecules, and Diseases

Volumn 42, Issue 2, 2009, Pages 99-104

  Chang, Jeffrey S ^a   Wiemels, Joseph L ^a   Buffler, Patricia A ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Allergy; Childhood leukemia; Immune function

Indexed keywords

CYTOKINE; TRANSCRIPTION FACTOR FOXP3;

ALLERGY; CHILDHOOD LEUKEMIA; CHROMOSOME TRANSLOCATION; ENVIRONMENTAL FACTOR; GENE MUTATION; GENETIC ANALYSIS; GENETIC POLYMORPHISM; HUMAN; HYGIENE; IMMUNITY; IMMUNOMODULATION; LYMPHATIC LEUKEMIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; REVIEW; TH1 CELL; TH17 CELL; TH2 CELL;

ADOLESCENT; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; CYTOKINES; ENVIRONMENTAL EXPOSURE; FEMALE; FETAL BLOOD; HUMANS; HYGIENE; HYPERSENSITIVITY; INFANT; INFANT, NEWBORN; INFECTION; LEUKEMIA; LYMPHOCYTE COUNT; MALE; MODELS, BIOLOGICAL; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; T-LYMPHOCYTE SUBSETS; TRANSLOCATION, GENETIC;

EID: 59449090713     PISSN: 10799796     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcmd.2008.10.003     Document Type: Review

References (81)

1. L.A.G. Ries, M.A. Smith, J.G. Gurney, M. Linet, T. Tamra, J.L. Young, and G.R. Bunin, (Eds.), Cancer Incidence and Survival among Children and Adolescents: United States SEER Program 1975-1995, National Cancer Institute, SEER Program. NIH Pub. No. 99-4649., Bethesda, MD, 1999.
2. In: Ries L.A.G., Eisner M.P., Kosary C.L., Hankey B.F., Miller B.A., Clegg L., Mariotto A., Feuer E.J., and Edwards B.K. (Eds). SEER Cancer Statistics Review, 1975-2002 (2005), National Cancer Institute, Bethesda, MD
3. Greaves M.F., and Alexander F.E. An infectious etiology for common acute lymphoblastic leukemia in childhood?. Leukemia 7 (1993) 349-360
4. Greaves M.F., and Wiemels J. Origins of chromosome translocations in childhood leukaemia. Nat. Rev. Cancer 3 (2003) 639-649
5. Mori H., Colman S.M., Xiao Z., Ford A.M., Healy L.E., Donaldson C., Hows J.M., Navarrete C., and Greaves M. Chromosome translocations and covert leukemic clones are generated during normal fetal development. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 8242-8247
6. Phares T.M., Morrow B., Lansky A., Barfield W.D., Prince C.B., Marchi K.S., Braveman P.A., Williams L.M., and Kinniburgh B. Surveillance for disparities in maternal health-related behaviors-selected states, pregnancy risk assessment monitoring system (PRAMS), 2000-2001. MMWR Surveill Summ. 53 (2004) 1-13
7. Higuchi M., O D., Brien, Kumaravelu P., Lenny N., Yeoh E.J., and Downing J.R. Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia. Cancer Cell 1 (2002) 63-74
8. Andreasson P., Schwaller J., Anastasiadou E., Aster J., and Gilliland D.G. The expression of ETV6/CBFA2 (TEL/AML1) is not sufficient for the transformation of hematopoietic cell lines in vitro or the induction of hematologic disease in vivo. Cancer Genet. Cytogenet. 130 (2001) 93-104
9. Rhoades K.L., Hetherington C.J., Harakawa N., Yergeau D.A., Zhou L., Liu L.Q., Little M.T., Tenen D.G., and Zhang D.E. Analysis of the role of AML1-ETO in leukemogenesis, using an inducible transgenic mouse model. Blood 96 (2000) 2108-2115
10. Bernardin F., Yang Y., Cleaves R., Zahurak M., Cheng L., Civin C.I., and Friedman A.D. TEL-AML1, expressed from t(12;21) in human acute lymphocytic leukemia, induces acute leukemia in mice. Cancer Res. 62 (2002) 3904-3908
11. Matsuno N., Osato M., Yamashita N., Yanagida M., Nanri T., Fukushima T., Motoji T., Kusumoto S., Towatari M., Suzuki R., Naoe T., Nishii K., Shigesada K., Ohno R., Mitsuya H., Ito Y., and Asou N. Dual mutations in the AML1 and FLT3 genes are associated with leukemogenesis in acute myeloblastic leukemia of the M0 subtype. Leukemia 17 (2003) 2492-2499
12. Yuan Y., Zhou L., Miyamoto T., Iwasaki H., Harakawa N., Hetherington C.J., Burel S.A., Lagasse E., Weissman I.L., Akashi K., and Zhang D.E. AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 10398-10403
13. Schessl C., Rawat V.P., Cusan M., Deshpande A., Kohl T.M., Rosten P.M., Spiekermann K., Humphries R.K., Schnittger S., Kern W., Hiddemann W., Quintanilla-Martinez L., Bohlander S.K., Feuring-Buske M., and Buske C. The AML1-ETO fusion gene and the FLT3 length mutation collaborate in inducing acute leukemia in mice. J. Clin. Invest. 115 (2005) 2159-2168
14. Greaves M. Infection, immune responses and the aetiology of childhood leukaemia. Nat. Rev. Cancer 6 (2006) 193-203
15. Kinlen L.J. Epidemiological evidence for an infective basis in childhood leukaemia. Br. J. Cancer 71 (1995) 1-5
16. Strachan D.P. Hay fever, hygiene, and household size. Bmj 299 (1989) 1259-1260
17. Westergaard T., Rostgaard K., Wohlfahrt J., Andersen P.K., Aaby P., and Melbye M. Sibship characteristics and risk of allergic rhinitis and asthma. Am. J. Epidemiol. 162 (2005) 125-132
18. Bernsen R.M., de Jongste J.C., and van der Wouden J.C. Birth order and sibship size as independent risk factors for asthma, allergy, and eczema. Pediatr. Allergy Immunol. 14 (2003) 464-469
19. Lewis S.A., and Britton J.R. Consistent effects of high socioeconomic status and low birth order, and the modifying effect of maternal smoking on the risk of allergic disease during childhood. Respir. Med. 92 (1998) 1237-1244
20. Matricardi P.M., Franzinelli F., Franco A., Caprio G., Murru F., Cioffi D., Ferrigno L., Palermo A., Ciccarelli N., and Rosmini F. Sibship size, birth order, and atopy in 11,371 Italian young men. J. Allergy Clin. Immunol. 101 (1998) 439-444
21. Strachan D.P., Taylor E.M., and Carpenter R.G. Family structure, neonatal infection, and hay fever in adolescence. Arch. Dis. Child. 74 (1996) 422-426
22. Haby M.M., Marks G.B., Peat J.K., and Leeder S.R. Daycare attendance before the age of two protects against atopy in preschool age children. Pediatr. Pulmonol. 30 (2000) 377-384
23. Kramer U., Heinrich J., Wjst M., and Wichmann H.E. Age of entry to day nursery and allergy in later childhood. Lancet 353 (1999) 450-454
24. Dockerty J.D., Draper G., Vincent T., Rowan S.D., and Bunch K.J. Case-control study of parental age, parity and socioeconomic level in relation to childhood cancers. Int. J. Epidemiol. 30 (2001) 1428-1437
25. Westergaard T., Andersen P.K., Pedersen J.B., Olsen J.H., Frisch M., Sorensen H.T., Wohlfahrt J., and Melbye M. Birth characteristics, sibling patterns, and acute leukemia risk in childhood: a population-based cohort study. J. Natl. Cancer Inst. 89 (1997) 939-947
26. Ma X., Buffler P.A., Selvin S., Matthay K.K., Wiencke J.K., Wiemels J.L., and Reynolds P. Daycare attendance and risk of childhood acute lymphoblastic leukaemia. Br. J. Cancer 86 (2002) 1419-1424
27. Ma X., Buffler P.A., Wiemels J.L., Selvin S., Metayer C., Loh M., Does M.B., and Wiencke J.K. Ethnic difference in daycare attendance, early infections, and risk of childhood acute lymphoblastic leukemia. Cancer Epidemiol. Biomarkers Prev. 14 (2005) 1928-1934
28. Perrillat F., Clavel J., Auclerc M.F., Baruchel A., Leverger G., Nelken B., Philippe N., Schaison G., Sommelet D., Vilmer E., and Hemon D. Day-care, early common infections and childhood acute leukaemia: a multicentre French case-control study. Br. J. Cancer 86 (2002) 1064-1069
29. Gilham C., Peto J., Simpson J., Roman E., Eden T.O., Greaves M.F., and Alexander F.E. Day care in infancy and risk of childhood acute lymphoblastic leukaemia: findings from UK case-control study. Bmj 330 (2005) 1294
30. Jourdan-Da Silva N., Perel Y., Mechinaud F., Plouvier E., Gandemer V., Lutz P., Vannier J.P., Lamagnere J.L., Margueritte G., Boutard P., Robert A., Armari C., Munzer M., Millot F., De Lumley L., Berthou C., Rialland X., Pautard B., Hemon D., and Clavel J. Infectious diseases in the first year of life, perinatal characteristics and childhood acute leukaemia. Br. J. Cancer 90 (2004) 139-145
31. McKinney P.A., Juszczak E., Findlay E., Smith K., and Thomson C.S. Pre-and perinatal risk factors for childhood leukaemia and other malignancies: a Scottish case control study. Br. J. Cancer 80 (1999) 1844-1851
32. MacArthur A.C., McBride M.L., Spinelli J.J., Tamaro S., Gallagher R.P., and Theriault G.P. Risk of childhood leukemia associated with vaccination, infection, and medication use in childhood: the Cross-Canada Childhood Leukemia Study. Am. J. Epidemiol. 167 (2008) 598-606
33. Naumburg E., Bellocco R., Cnattingius S., Jonzon A., and Ekbom A. Perinatal exposure to infection and risk of childhood leukemia. Med. Pediatr. Oncol. 38 (2002) 391-397
34. Roman E., Simpson J., Ansell P., Kinsey S., Mitchell C.D., McKinney P.A., Birch J.M., Greaves M., and Eden T. Childhood acute lymphoblastic leukemia and infections in the first year of life: a report from the United Kingdom Childhood Cancer Study. Am. J. Epidemiol. 165 (2007) 496-504
35. Nishi M., and Miyake H. A case-control study of non-T cell acute lymphoblastic leukaemia of children in Hokkaido, Japan. J. Epidemiol. Community Health 43 (1989) 352-355
36. Petridou E., Trichopoulos D., Kalapothaki V., Pourtsidis A., Kogevinas M., Kalmanti M., Koliouskas D., Kosmidis H., Panagiotou J.P., Piperopoulou F., and Tzortzatou F. The risk profile of childhood leukaemia in Greece: a nationwide case-control study. Br. J. Cancer 76 (1997) 1241-1247
37. Schuz J., Kaletsch U., Meinert R., Kaatsch P., and Michaelis J. Association of childhood leukaemia with factors related to the immune system. Br. J. Cancer 80 (1999) 585-590
38. Wen W., Shu X.O., Linet M.S., Neglia J.P., Potter J.D., Trigg M.E., and Robison L.L. Allergic disorders and the risk of childhood acute lymphoblastic leukemia (United States). Cancer Causes Control 11 (2000) 303-307
39. Schuz J., Morgan G., Bohler E., Kaatsch P., and Michaelis J. Atopic disease and childhood acute lymphoblastic leukemia. Int. J. Cancer 105 (2003) 255-260
40. Spector L., Groves F., DeStefano F., Liff J., Klein M., Mullooly J., Black S., Shinefield H., Ward J., and Marcy M. Medically recorded allergies and the risk of childhood acute lymphoblastic leukaemia. Eur. J. Cancer 40 (2004) 579-584
41. Rosenbaum P.F., Buck G.M., and Brecher M.L. Allergy and infectious disease histories and the risk of childhood acute lymphoblastic leukaemia. Paediatr. Perinat. Epidemiol. 19 (2005) 152-164
42. Hughes A.M., Lightfoot T., Simpson J., Ansell P., McKinney P.A., Kinsey S.E., Mitchell C.D., Eden T.O., Greaves M., and Roman E. Allergy and risk of childhood leukaemia: results from the UKCCS. Int. J. Cancer 121 (2007) 819-824
43. Romagnani S. The increased prevalence of allergy and the hygiene hypothesis: missing immune deviation, reduced immune suppression, or both?. Immunology 112 (2004) 352-363
44. Prescott S.L., Macaubas C., Holt B.J., Smallacombe T.B., Loh R., Sly P.D., and Holt P.G. Transplacental priming of the human immune system to environmental allergens: universal skewing of initial T cell responses toward the Th2 cytokine profile. J. Immunol. 160 (1998) 4730-4737
45. Prescott S.L., Macaubas C., Smallacombe T., Holt B.J., Sly P.D., Loh R., and Holt P.G. Reciprocal age-related patterns of allergen-specific T-cell immunity in normal vs. atopic infants. Clin. Exp. Allergy 28 Suppl 5 (1998) 39-44 discussion 50-1
46. Bach J.F. The effect of infections on susceptibility to autoimmune and allergic diseases. N. Engl. J. Med. 347 (2002) 911-920
47. Yazdanbakhsh M., Kremsner P.G., and van Ree R. Allergy, parasites, and the hygiene hypothesis. Science 296 (2002) 490-494
48. Sakaguchi S., Sakaguchi N., Asano M., Itoh M., and Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol. 155 (1995) 1151-1164
49. Wing K., Fehervari Z., and Sakaguchi S. Emerging possibilities in the development and function of regulatory T cells. Int. Immunol. 18 (2006) 991-1000
50. Romagnani S. Coming back to a missing immune deviation as the main explanatory mechanism for the hygiene hypothesis. J. Allergy Clin. Immunol. 119 (2007) 1511-1513
51. Ichiyama K., Yoshida H., Wakabayashi Y., Chinen T., Saeki K., Nakaya M., Takaesu G., Hori S., Yoshimura A., and Kobayashi T. Foxp3 inhibits ROR{gamma}t-mediated IL-17A mRNA transcription through direct interaction with ROR{gamma}t. J. Biol. Chem. 283 (2008) 17003-17008
52. McGeachy M.J., and Cua D.J. Th17 cell differentiation: the long and winding road. Immunity 28 (2008) 445-453
53. Oboki K., Ohno T., Saito H., and Nakae S. Th17 and allergy. Allergol. Intern. 57 (2008) 121-134
54. Papamichail M., Perez S.A., Gritzapis A.D., and Baxevanis C.N. Natural killer lymphocytes: biology, development, and function. Cancer Immunol. Immunother. 53 (2004) 176-186
55. Johnson C.C., Ownby D.R., and Peterson E.L. Parental history of atopic disease and concentration of cord blood IgE. Clin. Exp. Allergy 26 (1996) 624-629
56. Liu C.A., Wang C.L., Chuang H., Ou C.Y., Hsu T.Y., and Yang K.D. Prenatal prediction of infant atopy by maternal but not paternal total IgE levels. J. Allergy Clin. Immunol. 112 (2003) 899-904
57. Karmaus W., and Eneli I. Maternal atopy and the number of offspring: is there an association?. Pediatr. Allergy Immunol. 14 (2003) 470-474
58. Forastiere F., Sunyer J., Farchi S., Corbo G., Pistelli R., Baldacci S., Simoni M., Agabiti N., Perucci C.A., and Viegi G. Number of offspring and maternal allergy. Allergy 60 (2005) 510-514
59. Karmaus W., Arshad S.H., Sadeghnejad A., and Twiselton R. Does maternal immunoglobulin E decrease with increasing order of live offspring? Investigation into maternal immune tolerance. Clin. Exp. Allergy 34 (2004) 853-859
60. van Gool C.J., Thijs C., Dagnelie P.C., Henquet C.J., van Houwelingen A.C., Schrander J., Menheere P.P., and van den Brandt P.A. Determinants of neonatal IgE level: parity, maternal age, birth season and perinatal essential fatty acid status in infants of atopic mothers. Allergy 59 (2004) 961-968
61. Marschan E., Honkanen J., Kukkonen K., Kuitunen M., Savilahti E., and Vaarala O. Increased activation of GATA-3, IL-2 and IL-5 of cord blood mononuclear cells in infants with IgE sensitization. Pediatr. Allergy Immunol. 19 (2008) 132-139
62. Amoudruz P., Holmlund U., Malmstrom V., Trollmo C., Bremme K., Scheynius A., and Sverremark-Ekstrom E. Neonatal immune responses to microbial stimuli: is there an influence of maternal allergy?. J. Allergy Clin. Immunol. 115 (2005) 1304-1310
63. Schaub B., Campo M., He H., Perkins D., Gillman M.W., Gold D.R., Weiss S., Lieberman E., and Finn P.W. Neonatal immune responses to TLR2 stimulation: influence of maternal atopy on Foxp3 and IL-10 expression. Respir. Res. 7 (2006) 40
64. Fontenot J.D., and Rudensky A.Y. A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3. Nat. Immunol. 6 (2005) 331-337
65. Battaglia M., Gregori S., Bacchetta R., and Roncarolo M.G. Tr1 cells: from discovery to their clinical application. Semin. Immunol. 18 (2006) 120-127
66. Duramad P., Harley K., Lipsett M., Bradman A., Eskenazi B., Holland N.T., and Tager I.B. Early environmental exposures and intracellular Th1/Th2 cytokine profiles in 24-month-old children living in an agricultural area. Environ. Health Perspect. 114 (2006) 1916-1922
67. Noakes P.S., Holt P.G., and Prescott S.L. Maternal smoking in pregnancy alters neonatal cytokine responses. Allergy 58 (2003) 1053-1058
68. Noakes P.S., Hale J., Thomas R., Lane C., Devadason S.G., and Prescott S.L. Maternal smoking is associated with impaired neonatal toll-like-receptor-mediated immune responses. Eur. Respir. J. 28 (2006) 721-729
69. Madura Larsen J., Benn C.S., Fillie Y., van der Kleij D., Aaby P., and Yazdanbakhsh M. BCG stimulated dendritic cells induce an interleukin-10 producing T-cell population with no T helper 1 or T helper 2 bias in vitro. Immunology 121 (2007) 276-282
70. Linehan M.F., Frank T.L., Hazell M.L., Francis H.C., Morris J.A., Baxter D.N., and Niven R.M. Is the prevalence of wheeze in children altered by neonatal BCG vaccination?. J. Allergy Clin. Immunol. 119 (2007) 1079-1085
71. Hertz-Picciotto I., Park H.Y., Dostal M., Kocan A., Trnovec T., and Sram R. Prenatal exposures to persistent and non-persistent organic compounds and effects on immune system development. Basic Clin. Pharmacol. Toxicol. 102 (2008) 146-154
72. Schwartzbaum J.A., Ahlbom A., Lonn S., Malmer B., Wigertz A., Auvinen A., Brookes A.J., Collatz Christensen H., Henriksson R., Johansen C., Salminen T., Schoemaker M.J., Swerdlow A.J., Debinski W., and Feychting M. An international case-control study of interleukin-4Ralpha, interleukin-13, and cyclooxygenase-2 polymorphisms and glioblastoma risk. Cancer Epidemiol. Biomarkers Prev. 16 (2007) 2448-2454
73. Wiemels J.L., Wiencke J.K., Kelsey K.T., Moghadassi M., Rice T., Urayama K.Y., Miike R., and Wrensch M. Allergy-related polymorphisms influence glioma status and serum IgE levels. Cancer Epidemiol. Biomarkers Prev. 16 (2007) 1229-1235
74. Olson S.H., Orlow I., Simon J., Tommasi D., Roy P., Bayuga S., Ludwig E., Zauber A.G., and Kurtz R.C. Allergies, variants in IL-4 and IL-4R alpha genes, and risk of pancreatic cancer. Cancer Detec. Prev. 31 (2007) 345-351
75. Akira S., Takeda K., and Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat. Immunol. 2 (2001) 675-680
76. Liu G., and Zhao Y. Toll-like receptors and immune regulation: their direct and indirect modulation on regulatory CD4+ CD25+ T cells. Immunology 122 (2007) 149-156
77. Phillips T.M. Assessing environmental exposure in children: immunotoxicology screening. J. Expo. Anal. Environ. Epidemiol. 10 (2000) 769-775
78. Phillips T.M., and Krum J.M. Recycling immunoaffinity chromatography for multiple analyte analysis in biological samples. J. Chromatogr. B Biomed. Sci. Appl. 715 (1998) 55-63
79. Skogstrand K., Thorsen P., Norgaard-Pedersen B., Schendel D.E., Sorensen L.C., and Hougaard D.M. Simultaneous measurement of 25 inflammatory markers and neurotrophins in neonatal dried blood spots by immunoassay with xMAP technology. Clin. Chem. 51 (2005) 1854-1866
80. Harding N.J., Birch J.M., Hepworth S.J., and McKinney P.A. Atopic dysfunction and risk of central nervous system tumours in children. Eur. J. Cancer 44 (2008) 92-99
81. Menegaux F., Olshan A.F., Neglia J.P., Pollock B.H., and Bondy M.L. Day care, childhood infections, and risk of neuroblastoma. Am. J. Epidemiol. 159 (2004) 843-851