Synthesis and biological evaluation of vinca alkaloids and phomopsin hybrids

Journal of Medicinal Chemistry

Volumn 52, Issue 1, 2009, Pages 134-142

  Ngo, Quoc Anh ^a   Roussi, Fanny ^a   Cormier, Anthony ^b   Thoret, Sylviane ^a   Knossow, Marcel ^b   Guenard, Daniel ^a   Gueritte, Frangoise ^a  

^a CNRS   (France)

^b LABORATOIRE D ENZYMOLOGIE ET BIOCHIMIE STRUCTURALES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TUBULIN; BETA TUBULIN; NAVELBINE; PHOMOPSIN A; TUBULIN; VINBLASTINE; VINCA ALKALOID; ANTIMITOTIC AGENT; DRUG DERIVATIVE; MYCOTOXIN; PHOMOPSIN; TUBULIN MODULATOR;

ARTICLE; BINDING SITE; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MICROTUBULE ASSEMBLY; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; STRUCTURE ANALYSIS; CELL DEATH; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; IC 50; METABOLISM; MICROTUBULE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SYNTHESIS;

ANTIMITOTIC AGENTS; CELL DEATH; CELL LINE; INHIBITORY CONCENTRATION 50; MAGNETIC RESONANCE SPECTROSCOPY; MICROTUBULES; MOLECULAR STRUCTURE; MYCOTOXINS; TUBULIN; TUBULIN MODULATORS; VINBLASTINE; VINCA ALKALOIDS;

EID: 59449089370     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm801064y     Document Type: Article

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