Isolation and structure of an antimitotic cyclic peptide, ustiloxin F: Chemical interrelation with a homologous peptide, ustiloxin B

Journal of Antibiotics

Volumn 51, Issue 4, 1998, Pages 418-422

  Koiso, Yukiko ^b   Morisaki, Naoko ^b   Yamashita, Yukiko ^b   Mitsui, Yukiko ^b   Shirai, Ryuichi ^b   Hashimoto, Yuichi ^b   Iwasaki, Shigeo ^a,b  

^a KITASATO INSTITUTE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMITOTIC AGENT; MICROTUBULE PROTEIN; UNCLASSIFIED DRUG; USTILOXIN B; USTILOXIN F;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DEPOLYMERIZATION; DRUG ISOLATION; DRUG POTENCY; FAST ATOM BOMBARDMENT MASS SPECTROMETRY; FUNGUS CULTURE; MICROTUBULE ASSEMBLY; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN POLYMERIZATION; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 0031980548     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.51.418     Document Type: Article

References (6)

1. KOISO, Y.; M. NATORI, S. IWASAKI, S. SATO, R. SONODA, Y. FUJITA, H. YAEGASHI & Z. SATO: Ustiloxin: A phytoloxin and a mycotoxin from false smut balls on rice panicles. Tetrahedron Letters 33: 4157-4160, 1992
2. KOISO, Y.; Y. LI, S. IWASAKI, K. HANAOKA, T. KOBAYASHI, R. SONODA, Y. FUJITA, H. YAEGASHI & Z. SATO: Ustiloxins, antimitotic cyclic peptides from false smut balls on rice panicles caused by Ustilaginoidea virens. J. Antibiotics 47: 765-773, 1994
3. LI, Y.; Y. KOISO, H. KOBAYASHI, Y. HASHIMOTO & S. IWASAKI: Ustiloxins, new antimitotic cyclic peptides: Interaction with porcine brain tubulin. Biochem. Pharmacol. 49: 1367-1372, 1995
4. Ustiloxin E was assumed to be a degradation product of 1. Its structure has not been determined (see ref. 2).
5. SCHWOEGLER, E. J. & H. ADKINS: Preparation of certain amines. J. Am. Chem. Soc. 61: 3499-3502, 1939
6. 2) were revised.