-
1
-
-
0031855642
-
Investigation of the Streptomyces clavuligerus cephamycin gene cluster and its regulation by the CcaR
-
D Alexander SE Jensen 1998 Investigation of the Streptomyces clavuligerus cephamycin gene cluster and its regulation by the CcaR J Bacteriol 180 4068 4079
-
(1998)
J Bacteriol
, vol.180
, pp. 4068-4079
-
-
Alexander, D.1
Jensen, S.E.2
-
2
-
-
0032766134
-
The cytoplasmic helical linker domain of receptor histidine kinase and methyl-accepting proteins is common to many prokaryotic signaling proteins
-
doi: 10.1016/S0378-1097(99)00197-4 ; doi: 10.1111/j.1574-6968.1999. tb13650.x
-
Aravind L, Ponting CP (1999) The cytoplasmic helical linker domain of receptor histidine kinase and methyl-accepting proteins is common to many prokaryotic signaling proteins. FEMS Microbiol Lett 176:111-116. doi: 10.1016/S0378-1097(99)00197-4 ; doi: 10.1111/j.1574-6968.1999.tb13650.x
-
(1999)
FEMS Microbiol Lett
, vol.176
, pp. 111-116
-
-
Aravind, L.1
Ponting, C.P.2
-
3
-
-
0037046560
-
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)
-
10.1038/417141a
-
SD Bentley KF Chater AM Cerdeño-Tárraga GL Challis NR Thomson KD James DE Harris MA Quail H Kieser D Harper A Bateman S Brown G Chandra CW Chen M Collins A Cronin A Fraser A Goble J Hidalgo T Hornsby S Howarth CH Huang T Kieser L Larke L Murphy K Oliver S O'Neil E Rabbinowitsch MA Rajandream K Rutherford S Rutter K Seeger D Saunders S Sharp R Squares S Squares K Taylor T Warren A Wietzorrek J Woodward BG Barrell J Parkhill DA Hopwood 2002 Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2) Nature 417 141 147 10.1038/417141a
-
(2002)
Nature
, vol.417
, pp. 141-147
-
-
Bentley, S.D.1
Chater, K.F.2
Cerdeño-Tárraga, A.M.3
Challis, G.L.4
Thomson, N.R.5
James, K.D.6
Harris, D.E.7
Quail, M.A.8
Kieser, H.9
Harper, D.10
Bateman, A.11
Brown, S.12
Chandra, G.13
Chen, C.W.14
Collins, M.15
Cronin, A.16
Fraser, A.17
Goble, A.18
Hidalgo, J.19
Hornsby, T.20
Howarth, S.21
Huang, C.H.22
Kieser, T.23
Larke, L.24
Murphy, L.25
Oliver, K.26
O'Neil, S.27
Rabbinowitsch, E.28
Rajandream, M.A.29
Rutherford, K.30
Rutter, S.31
Seeger, K.32
Saunders, D.33
Sharp, S.34
Squares, R.35
Squares, S.36
Taylor, K.37
Warren, T.38
Wietzorrek, A.39
Woodward, J.40
Barrell, B.G.41
Parkhill, J.42
Hopwood, D.A.43
more..
-
4
-
-
0029891143
-
Global negative regulation of Streptomyces coelicolor antibiotic synthesis mediated by an absA-encoded putative signal transduction system
-
P Brian PJ Riggle RA Santos WC Champness 1996 Global negative regulation of Streptomyces coelicolor antibiotic synthesis mediated by an absA-encoded putative signal transduction system J Bacteriol 178 3221 3231
-
(1996)
J Bacteriol
, vol.178
, pp. 3221-3231
-
-
Brian, P.1
Riggle, P.J.2
Santos, R.A.3
Champness, W.C.4
-
6
-
-
0036203066
-
Structure of the bacterial RNA polymerase promoter specificity sigma subunit
-
10.1016/S1097-2765(02)00470-7
-
EA Campbell O Muzzin M Chlenov JL Sun CA Olson O Weinman ML Trester-Zedlitz SA Darst 2002 Structure of the bacterial RNA polymerase promoter specificity sigma subunit Mol Cell 9 527 539 10.1016/S1097-2765(02)00470-7
-
(2002)
Mol Cell
, vol.9
, pp. 527-539
-
-
Campbell, E.A.1
Muzzin, O.2
Chlenov, M.3
Sun, J.L.4
Olson, C.A.5
Weinman, O.6
Trester-Zedlitz, M.L.7
Darst, S.A.8
-
7
-
-
0029821306
-
The cutRS signal transduction system of Streptomyces lividans represses the biosynthesis of the polyketide antibiotic actinorhodin
-
HM Chang MY Chen YT Shieh MJ Bibb CW Chen 1996 The cutRS signal transduction system of Streptomyces lividans represses the biosynthesis of the polyketide antibiotic actinorhodin Mol Microbiol 21 1075 1085
-
(1996)
Mol Microbiol
, vol.21
, pp. 1075-1085
-
-
Chang, H.M.1
Chen, M.Y.2
Shieh, Y.T.3
Bibb, M.J.4
Chen, C.W.5
-
9
-
-
0033985080
-
GHKL, an emergent ATPase/kinase superfamily
-
10.1016/S0968-0004(99)01503-0
-
R Dutta M Inouye 2000 GHKL, an emergent ATPase/kinase superfamily Trends Biochem Sci 25 24 28 10.1016/S0968-0004(99)01503-0
-
(2000)
Trends Biochem Sci
, vol.25
, pp. 24-28
-
-
Dutta, R.1
Inouye, M.2
-
10
-
-
0037452723
-
PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin
-
10.1073/pnas.0337542100
-
B Gust GL Challis K Fowler T Kieser KF Chater 2003 PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin Proc Natl Acad Sci USA 100 1541 1546 10.1073/pnas.0337542100
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 1541-1546
-
-
Gust, B.1
Challis, G.L.2
Fowler, K.3
Kieser, T.4
Chater, K.F.5
-
11
-
-
4844230017
-
Sensing and responding to diverse extracellular signals? Analysis of the sensor kinases and response regulators of Streptomyces coelicolor A3(2)
-
10.1099/mic.0.27181-0
-
MI Hutchings PA Hoskisson G Chandra MJ Buttner 2004 Sensing and responding to diverse extracellular signals? Analysis of the sensor kinases and response regulators of Streptomyces coelicolor A3(2) Microbiology 150 2795 2806 10.1099/mic.0.27181-0
-
(2004)
Microbiology
, vol.150
, pp. 2795-2806
-
-
Hutchings, M.I.1
Hoskisson, P.A.2
Chandra, G.3
Buttner, M.J.4
-
12
-
-
0026490160
-
A putative two-component regulatory system involved in secondary metabolism in Streptomyces spp
-
H Ishizuka S Horinouchi HM Kieser DA Hopwood T Beppu 1992 A putative two-component regulatory system involved in secondary metabolism in Streptomyces spp J Bacteriol 23 7585 7594
-
(1992)
J Bacteriol
, vol.23
, pp. 7585-7594
-
-
Ishizuka, H.1
Horinouchi, S.2
Kieser, H.M.3
Hopwood, D.A.4
Beppu, T.5
-
13
-
-
0034004958
-
Enzymes catalyzing the early steps of clavulanic acid biosynthesis are encoded by two sets of paralogous genes in Streptomyces clavuligerus
-
10.1128/AAC.44.3.720-726.2000
-
SE Jensen KJ Elder KA Aidoo AS Paradkar 2000 Enzymes catalyzing the early steps of clavulanic acid biosynthesis are encoded by two sets of paralogous genes in Streptomyces clavuligerus Antimicrob Agents Chemother 44 720 726 10.1128/AAC.44.3.720-726.2000
-
(2000)
Antimicrob Agents Chemother
, vol.44
, pp. 720-726
-
-
Jensen, S.E.1
Elder, K.J.2
Aidoo, K.A.3
Paradkar, A.S.4
-
14
-
-
0347361709
-
Five additional genes are involved in clavulanic acid biosynthesis in Streptomyces clavuligerus
-
10.1128/AAC.48.1.192-202.2004
-
SE Jensen AS Paradkar RH Mosher C Anders PH Beatty MJ Brumlik A Griffin B Barton 2004 Five additional genes are involved in clavulanic acid biosynthesis in Streptomyces clavuligerus Antimicrob Agents Chemother 48 192 202 10.1128/AAC.48.1.192-202.2004
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 192-202
-
-
Jensen, S.E.1
Paradkar, A.S.2
Mosher, R.H.3
Anders, C.4
Beatty, P.H.5
Brumlik, M.J.6
Griffin, A.7
Barton, B.8
-
15
-
-
4644349000
-
Cephamycin C production is regulated by relA and rsh genes in Streptomyces clavuligerus ATCC27064
-
10.1016/j.jbiotec.2004.06.010
-
W Jin HK Kim JY Kim SG Kang SH Lee KJ Lee 2004 Cephamycin C production is regulated by relA and rsh genes in Streptomyces clavuligerus ATCC27064 J Biotechnol 114 81 87 10.1016/j.jbiotec.2004.06.010
-
(2004)
J Biotechnol
, vol.114
, pp. 81-87
-
-
Jin, W.1
Kim, H.K.2
Kim, J.Y.3
Kang, S.G.4
Lee, S.H.5
Lee, K.J.6
-
16
-
-
0036214541
-
Structure/function relationships in OmpR and other winged-helix transcription factors
-
10.1016/S1369-5274(02)00310-7
-
LJ Kenney 2002 Structure/function relationships in OmpR and other winged-helix transcription factors Curr Opin Microbiol 5 135 141 10.1016/S1369-5274(02)00310-7
-
(2002)
Curr Opin Microbiol
, vol.5
, pp. 135-141
-
-
Kenney, L.J.1
-
17
-
-
0032877650
-
Origin of the β-lactam carbons in clavulanic acid from an unusual thiamine pyrophosphate-mediated reaction
-
10.1021/ja9923134
-
N Khaleeli R Li CA Townsend 1999 Origin of the β-lactam carbons in clavulanic acid from an unusual thiamine pyrophosphate-mediated reaction J Am Chem Soc 121 9223 9224 10.1021/ja9923134
-
(1999)
J Am Chem Soc
, vol.121
, pp. 9223-9224
-
-
Khaleeli, N.1
Li, R.2
Townsend, C.A.3
-
18
-
-
59449103969
-
-
The John Innes Foundation Norwich
-
Kieser T, Bibb MJ, Butter MJ, Chater KF, Hopwood DA (2000) Practical Streptomyces genetics. The John Innes Foundation, Norwich
-
(2000)
-
-
Kieser, T.1
Bibb, M.J.2
Butter, M.J.3
Chater, K.F.4
Hopwood, D.A.5
-
19
-
-
0033933826
-
Expansion of the clavulanic acid gene cluster: Identification and in vivo functional analysis of three new genes required for biosynthesis of clavulanic acid by Streptomyces clavuligerus
-
10.1128/JB.182.14.4087-4095.2000
-
R Li N Khaleeli CA Townsend 2000 Expansion of the clavulanic acid gene cluster: identification and in vivo functional analysis of three new genes required for biosynthesis of clavulanic acid by Streptomyces clavuligerus J Bacteriol 182 4087 4095 10.1128/JB.182.14.4087-4095.2000
-
(2000)
J Bacteriol
, vol.182
, pp. 4087-4095
-
-
Li, R.1
Khaleeli, N.2
Townsend, C.A.3
-
20
-
-
0027439293
-
Precusor flux control through targeted chromosomal insertion of the lysine ε-aminotransferase (lat) gene in cephamycin C biosynthesis
-
LH Malmberg WS Hu DH Sherman 1993 Precusor flux control through targeted chromosomal insertion of the lysine ε-aminotransferase (lat) gene in cephamycin C biosynthesis J Bacteriol 175 6916 6924
-
(1993)
J Bacteriol
, vol.175
, pp. 6916-6924
-
-
Malmberg, L.H.1
Hu, W.S.2
Sherman, D.H.3
-
21
-
-
0036260378
-
The clavulanic acid biosynthetic cluster of Streptomyces clavuligerus: Genetic organization of the region upstream of the car gene
-
E Mellado LM Lorenzana M Rodríguez-Sáiz B Díez P Liras JL Barredo 2002 The clavulanic acid biosynthetic cluster of Streptomyces clavuligerus: genetic organization of the region upstream of the car gene Microbiology 148 1427 1438
-
(2002)
Microbiology
, vol.148
, pp. 1427-1438
-
-
Mellado, E.1
Lorenzana, L.M.2
Rodríguez-Sáiz, M.3
Díez, B.4
Liras, P.5
Barredo, J.L.6
-
22
-
-
0029135041
-
Giant linear plasmids of β-lactam antibiotic producing Streptomyces
-
10.1016/0378-1097(95)00230-3
-
DJ Netolitzky X Wu SE Jensen KL Roy 1995 Giant linear plasmids of β-lactam antibiotic producing Streptomyces FEMS Microbiol Lett 131 27 34 10.1016/0378-1097(95)00230-3
-
(1995)
FEMS Microbiol Lett
, vol.131
, pp. 27-34
-
-
Netolitzky, D.J.1
Wu, X.2
Jensen, S.E.3
Roy, K.L.4
-
24
-
-
0031891879
-
A pathway-specific transcriptional activator regulates late steps of clavulanic acid biosynthesis in Streptomyces clavuligerus
-
10.1046/j.1365-2958.1998.00731.x
-
AS Paradkar KA Aidoo SE Jensen 1998 A pathway-specific transcriptional activator regulates late steps of clavulanic acid biosynthesis in Streptomyces clavuligerus Mol Microbiol 27 831 843 10.1046/j.1365-2958.1998.00731.x
-
(1998)
Mol Microbiol
, vol.27
, pp. 831-843
-
-
Paradkar, A.S.1
Aidoo, K.A.2
Jensen, S.E.3
-
25
-
-
0035347174
-
Applications of gene replacement technology to Streptomyces clavuligerus strain development for clavulanic acid production
-
10.1128/AEM.67.5.2292-2297.2001
-
AS Paradkar RH Mosher C Anders A Griffin J Griffin C Hughes P Greaves B Barton SE Jensen 2001 Applications of gene replacement technology to Streptomyces clavuligerus strain development for clavulanic acid production Appl Environ Microbiol 67 2292 2297 10.1128/AEM.67.5.2292-2297.2001
-
(2001)
Appl Environ Microbiol
, vol.67
, pp. 2292-2297
-
-
Paradkar, A.S.1
Mosher, R.H.2
Anders, C.3
Griffin, A.4
Griffin, J.5
Hughes, C.6
Greaves, P.7
Barton, B.8
Jensen, S.E.9
-
26
-
-
0030954966
-
A regulatory gene (ccaR) required for cephamycin and clavulanic acid production in Streptomyces clavuligerus: Amplification results in overproduction of both β-lactam compounds
-
FJ Pérez-Llarena P Liras A Rodríguez-García JF Martín 1997 A regulatory gene (ccaR) required for cephamycin and clavulanic acid production in Streptomyces clavuligerus: amplification results in overproduction of both β-lactam compounds J Bacteriol 179 2053 2059
-
(1997)
J Bacteriol
, vol.179
, pp. 2053-2059
-
-
Pérez-Llarena, F.J.1
Liras, P.2
Rodríguez-García, A.3
Martín, J.F.4
-
27
-
-
0032510817
-
The claR gene of Streptomyces clavuligerus, encoding a LysR-type regulatory protein controlling clavulanic acid biosynthesis, is linked to the clavulanate-9-aldehyde reductase (car) gene
-
10.1016/S0378-1119(98)00106-1
-
R Pérez-Redondo A Rodríguez-García JF Martín P Liras 1998 The claR gene of Streptomyces clavuligerus, encoding a LysR-type regulatory protein controlling clavulanic acid biosynthesis, is linked to the clavulanate-9-aldehyde reductase (car) gene Gene 211 311 321 10.1016/S0378-1119(98)00106-1
-
(1998)
Gene
, vol.211
, pp. 311-321
-
-
Pérez-Redondo, R.1
Rodríguez-García, A.2
Martín, J.F.3
Liras, P.4
-
28
-
-
0345440126
-
Deletion of the pyc gene blocks clavulanic acid biosynthesis except in glycerol-containing medium: Evidence for two different genes in formation of the C3 unit
-
R Pérez-Redondo A Rodríguez-García JF Martín P Liras 1999 Deletion of the pyc gene blocks clavulanic acid biosynthesis except in glycerol-containing medium: evidence for two different genes in formation of the C3 unit J Bacteriol 181 6922 6928
-
(1999)
J Bacteriol
, vol.181
, pp. 6922-6928
-
-
Pérez-Redondo, R.1
Rodríguez-García, A.2
Martín, J.F.3
Liras, P.4
-
29
-
-
59449106433
-
-
2 Cold Spring Harbor Laboratory Cold Spring Harbor
-
Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning: a laboratory manual, 2nd edn. Cold Spring Harbor Laboratory, Cold Spring Harbor
-
(1989)
-
-
Sambrook, J.1
Fritsch, E.F.2
Maniatis, T.3
-
30
-
-
0038284769
-
The two component PhoR-PhoP system controls both primary metabolism and secondary metabolite biosynthesis in Streptomyces lividans
-
10.1073/pnas.0931429100
-
A Sola-Landa RS Moura JF Martín 2003 The two component PhoR-PhoP system controls both primary metabolism and secondary metabolite biosynthesis in Streptomyces lividans Proc Natl Acad Sci USA 100 6133 6138 10.1073/pnas. 0931429100
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 6133-6138
-
-
Sola-Landa, A.1
Moura, R.S.2
Martín, J.F.3
-
31
-
-
0344142378
-
Three-dimensional crystal structure of the transcription factor PhoB receiver domain
-
10.1006/jmbi.1998.2326
-
M Solá FX Gomis-Rüth L Serrano A González M Coll 1999 Three-dimensional crystal structure of the transcription factor PhoB receiver domain J Mol Biol 285 675 687 10.1006/jmbi.1998.2326
-
(1999)
J Mol Biol
, vol.285
, pp. 675-687
-
-
Solá, M.1
Gomis-Rüth, F.X.2
Serrano, L.3
González, A.4
Coll, M.5
-
32
-
-
46749104581
-
Functional effects of increased copy number of the gene encoding proclavaminate amidino hydrolase on clavulanic acid production in Streptomyces clavuligerus ATCC 27064
-
JY Song ES Kim DW Kim SE Jensen KJ Lee 2008 Functional effects of increased copy number of the gene encoding proclavaminate amidino hydrolase on clavulanic acid production in Streptomyces clavuligerus ATCC 27064 J Microbiol Biotechnol 3 417 426
-
(2008)
J Microbiol Biotechnol
, vol.3
, pp. 417-426
-
-
Song, J.Y.1
Kim, E.S.2
Kim, D.W.3
Jensen, S.E.4
Lee, K.J.5
-
33
-
-
11044239452
-
Three unlinked gene clusters are involved in clavam metabolite biosynthesis in Streptomyces clavuligerus
-
10.1139/w04-070
-
K Tahlan HU Park SE Jensen 2004 Three unlinked gene clusters are involved in clavam metabolite biosynthesis in Streptomyces clavuligerus Can J Microbiol 50 803 810 10.1139/w04-070
-
(2004)
Can J Microbiol
, vol.50
, pp. 803-810
-
-
Tahlan, K.1
Park, H.U.2
Jensen, S.E.3
-
34
-
-
1442300124
-
Two sets of paralogous genes encode the enzymes involved in the early stages of clavulanic acid and clavam biosynthesis in Streptomyces clavuligerus
-
10.1128/AAC.48.3.930-939.2004
-
K Tahlan HU Park A Wong PH Beatty SE Jensen 2004 Two sets of paralogous genes encode the enzymes involved in the early stages of clavulanic acid and clavam biosynthesis in Streptomyces clavuligerus Antimicrob Agents Chemother 48 930 939 10.1128/AAC.48.3.930-939.2004
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 930-939
-
-
Tahlan, K.1
Park, H.U.2
Wong, A.3
Beatty, P.H.4
Jensen, S.E.5
-
35
-
-
0032804404
-
Solution structure of the homodimeric core domain of Escherichia coli histidine kinase EnvZ
-
10.1038/11495
-
C Tomomori T Tanaka R Dutta H Park SK Saha Y Zhu R Ishima D Liu KI Tong H Kurokawa H Qian M Inouye M Ikura 1999 Solution structure of the homodimeric core domain of Escherichia coli histidine kinase EnvZ Nat Struct Biol 6 729 734 10.1038/11495
-
(1999)
Nat Struct Biol
, vol.6
, pp. 729-734
-
-
Tomomori, C.1
Tanaka, T.2
Dutta, R.3
Park, H.4
Saha, S.K.5
Zhu, Y.6
Ishima, R.7
Liu, D.8
Tong, K.I.9
Kurokawa, H.10
Qian, H.11
Inouye, M.12
Ikura, M.13
-
36
-
-
0027289141
-
The biosynthetic genes for clavulanic acid and cephamycin production occur as a 'supercluster' in three Streptomyces
-
10.1111/j.1574-6968.1993.tb06326.x
-
JM Ward JE Hodgson 1993 The biosynthetic genes for clavulanic acid and cephamycin production occur as a 'supercluster' in three Streptomyces FEMS Microbiol Lett 110 239 242 10.1111/j.1574-6968.1993.tb06326.x
-
(1993)
FEMS Microbiol Lett
, vol.110
, pp. 239-242
-
-
Ward, J.M.1
Hodgson, J.E.2
|